Isifo sikashukela i-mellitus singenye yezifo eziyingozi kakhulu ezingadala inani eliphezulu lezinkinga.
Ngenxa yezinga likashukela elanda njalo nokuxineka ngokweqile kwe-glucose egazini, ukubhujiswa kwezicubu cishe kuzo zonke izitho kwenzeka.
Ngakho-ke, kubalulekile ukukwazi ukulawula lezi zinkomba futhi uzigcine zisezingeni “eliphilile”. Ngale njongo, iziguli zingabekelwa izidakamizwa okuhloswe ngazo ukunciphisa nokuqinisa izinkomba zoshukela kanye noshukela, ezibandakanya i-Glucofage neMetformin.
Ukwakheka
I-Glucophage imakethwa ngendlela yethebhulethi. Uhlobo ngalunye lwesidakamizwa luqukethe inani elihlukile lezinto eziphambili ezisebenzayo, ukuze kukhethwe umuthi kungenzeka ngokuya ngezinga lokunganakwa kwalesi sifo.
Isithako esiyinhloko ekwakhekeni kwamacwecwe, anesibopho sokuqinisekisa izakhiwo ze-hypoglycemic, yi-metformin hydrochloride equkethwe kumathebhulethi we-Glucofage ngamanani alandelayo:
- IGlucophage 500 iqukethe into esebenzayo ngenani lama-500 mg;
- I-Glucofage 850 iqukethe ama-850 mg wesithako sesisekelo;
- I-Glucophage 1000 iqukethe i-1000 mg yento esemqoka, enikeza umphumela wokwehlisa ushukela;
- I-Glucophage XR ifaka i-500 mg yento esemqoka.
IMetformin iyaqhubeka nokuthengiswa ngohlobo lwezibhebhe, isithako esikhulu esisebenzayo ekuyiMetformin.
Iziguli zingathenga amaphilisi aqukethe ama-500 mg noma ama-850 mg wesithako esiyinhloko.
Isenzo sezidakamizwa
IGlucophage yisidakamizwa esenzelwe ukuphathwa komlomo kanye nezakhiwo ze-hypoglycemic. Ukwakheka kwalesi sidakamizwa kuqukethe into "ehlakaniphile" - i-metformin.
Izibhebhe ze-Glucofage 1000 mg
Isici esihlukile sale ngxenye yikhono lokuphendula imvelo futhi likhiphe umphumela ofanele ngokuhambisana nezimo. Okusho ukuthi, into iba nomphumela we-hypoglycemic kuphela uma izinga le-glucose ku-plasma yegazi lidlulwa. Kubantu abanamazinga ajwayelekile, umuthi awubangeli ukwehla kwamazinga kashukela.
Ukuthatha umuthi kukhulisa ukuzwela kwezicubu ukungena ku-insulin futhi kuvimbela ukumuncwa kwe-glucose ngohlelo lokugaya ukudla, ngenxa yokuthi ukuhlushwa kwalo egazini kuncipha. Umuthi unomphumela osheshayo emzimbeni, ngoba umunwa izicubu ngesikhathi esifushane.
Metformin 850 mg
I-Metformin ingesinye isidakamizwa esilwa nesifo sikashukela sokusetshenziswa kwangaphakathi esinezakhiwo ze-hypoglycemic. Umuthi awunagalelo ekukhiqizweni kwe-insulin, ngakho-ke, lapho uthathwa, ukwehla ngokweqile kwezinga le-glucose akufakiwe.
Umuthi osebenzayo oqukethwe umuthi uvimbela i-gluconeogeneis, okuholela ekuncipheni kwamazinga kashukela wonke, kanye nokwehla kwenani le-glucose ekhona egazini ngemuva kokudla. Ngenxa yalomphumela, isimo sesiguli senziwa ngendlela ejwayelekile, futhi ukuqala kwesifo sikashukela kukhishwe ngaphandle.
Uyini umehluko?
Ngaphezu kwento esemqoka esebenzayo, indlela yokusebenza emzimbeni, iGlucophage ihlukile kuneMetformin ohlwini lwezinkomba ezisetshenziswayo.
I-Metformin inqunyelwe iziguli ezindala ezitholwe isifo sikashukela sohlobo 1 nohlobo 2.
Umuthi ungasetshenziswa ekwelapheni okuyinkimbinkimbi kwe-antidiabetic kuhlanganiswe ne-insulin nezinye izidakamizwa ezifakiwe kwinqubo yokwelashwa, kanye nomuthi owodwa (ngokwesibonelo, onesifo sikashukela sohlobo 1, iMetformin isetshenziswa, uyihlanganisa kuphela ne-insulin).
Futhi, umuthi uyanconywa ukuthi usetshenziswe ezimweni lapho isiguli sinokukhuluphala okukhona okuphazamisa ukujwayelekile kwamazinga kashukela ngokuzivocavoca nangokudla.
I-Metformin yiso kuphela isidakamizwa esinezimpawu zokulwa nesifo sikashukela futhi sisize ukuvikela ukuthuthukiswa kwezinkinga kanye nengozi yesifo senhliziyo.
IGlucophage ibekelwe iziguli ezinesifo sikashukela sohlobo 2, lapho ukudla nokudla kungazange kunikeze umphumela ofunekayo.
Umuthi lo ungasetjenziswa njengesidakamizwa esisodwa nanyana uhlanganiswe nezinye izidakamizwa ezokwehlisa izinga le-glucose.
IGlucophage ibekelwe izingane ezingaphezulu kweminyaka engu-10 ubudala, uyixube namanye ama-hypoglycemic agents noma njenge-monotherapy.
I-Metformin, iSiofor noma iGlucofage: yini engcono?
Kuyafaneleka ukusho ngaso leso sikhathi ukuthi ukukhethwa komuthi esimweni ngasinye somtholampilo ngamunye kufanele kwenziwe udokotela. IGlucophage neSiofor yizifanekiselo zomunye nomunye. Ukwakheka kwabo, izakhiwo zamakhemikhali, into esemqoka esebenzayo nomphumela wohlelo lokusebenza kuzofana. Umehluko omncane ungaba ngentengo.
Amacwecwe eSiofor 850 mg
Kuzo zonke ezinye izindlela, amalungiselelo afana kakhulu, futhi izici zokuzikhethela kwazo zincike ezicini zenkambo yesifo kanye nezinga lokunganakwa kwayo. Ngalesi sizathu, ukukhethwa kwemithi kufanele kwenziwe ngudokotela ohambele kuye ngemiphumela yokuhlolwa nokuhlolwa kwezokwelashwa.
IGlucophage ihlukile kuSiofor kulezi zici ezilandelayo:
- IGlucophage inenombolo ecatshangelwayo yemiphumela emibi, ngakho-ke inani lokubuyekezwa lelo muthi elalingalingani lizoba likhulu maqondana nalo muthi kunokuhlobene neSiofor noma iMetformin;
- IGlucophage inezindleko eziphakeme kuneSiofor. Ngakho-ke, uma umbuzo uyintengo yesidakamizwa, isiguli singakhetha inketho ehambelana namandla wezezimali;
- kufanele unake iqiniso lokuthi esimweni sokwelashwa isikhathi eside, kuzodingeka uthenge umuthi obhalwe ukuthi "Isikhathi Eside". Ukuqanjwa kwayo kulungele ukusetshenziswa kwesikhathi eside, kepha izindleko zamaphilisi zizokwenyuka.
Ngaphandle kokungafani, ukusebenza ngempumelelo kwale mishanguzo engenhla kungahluka. Konke kuzoncika ezimweni zomzimba ngazinye, nasendleleni, uhlobo lwesifo kanye nokugula okuhambisana nakho okubangelwa ushukela.
Contraindication
Lapho ukhetha umuthi, kufanele unake ngokuphelele ama-contraindication umuthi onawo. Kulokhu, kungenzeka ukuletha inzuzo ephezulu yomzimba, ususe imiphumela emibi.
Phakathi kokuphikiswa ukuthi iGlucophage inakho kufaka phakathi:
- ukusabela komzimba ngamunye ezingxenyeni zomuthi;
- isifo sikashukela sikashukela, ikoma noma i-precom;
- umsebenzi wezinso ongonakalisiwe;
- ukugula kwesimo esibi nesingamahlalakhona, esihambisana ne-hypoxia, ukushaya kwenhliziyo, ukwehluleka kwenhliziyo;
- ukungenelela kokuhlinzwa okuzayo;
- ukwephulwa kwesibindi;
- ezinye izimo ezithile.
Phakathi kwezimo lapho ukuthatha i-Metformin kungafuneki kufaka phakathi:
- iminyaka engaphansi kweminyaka eyi-15;
- isifo sikashukela noma i-ketoacidosis;
- gangren
- unyawo lwesifo sikashukela;
- ukushaya kwenhliziyo okukhulu;
- ukwehluleka kwesibindi;
- ukucaphuna noma ukukhulelwa;
- ezinye izimo ezithile.
Amavidiyo ahlobene
Ezintweni ezingezinhle zokusebenzisa izidakamizwa iMetformin, iSiofor, neGlucofage kuvidiyo:
Ngokukhetha okufanele kwezidakamizwa, ukuthuthuka okusheshayo nokuqina kwesimo sesiguli kungenzeka. Ukufeza umphumela onjalo, ungazenzisi futhi ungasebenzisi izeluleko zabangani njengesisekelo. Uma kwenzeka uthola izimpawu ezethusayo, thintana nodokotela ngokushesha futhi uhlolwe ngokuphelele.
