Ukulawula ushukela wegazi yisimo esiyisisekelo sokulwa ngempumelelo nesifo sikashukela.
Uma kungenakwenzeka ukugcina izinkomba ezijwayelekile ngosizo lokudla nokuzivocavoca umzimba, ama-hypoglycemic agents kufanele asetshenziswe. Phakathi kwazo kungabizwa umuthi iGlycvidon, owaziwa nangokuthi ngaphansi kwegama lokuhweba iGlyurenorm.
Imininingwane ejwayelekile
Umuthi ususelwa entweni enegama elifanayo. Inezindawo eziyindalo ze-hypoglycemic. Umuthi uhloselwe ukulwa ne-mellitus engavunyelwe yi-insulin.
Ingxenye yayo eyinhloko inefomu lempuphu emhlophe, encibilikiswa kancane otshwaleni futhi ayincibiliki emanzini.
Njengoba leli khambi lithinta okuqukethwe ushukela egazini, ukusetshenziswa kwalo ngokungalawulwa kungadala ukuphazamiseka emsebenzini womzimba ohambisana ne-hypoglycemia. Ngakho-ke, iziguli kufanele zilandele imiyalo evela kuchwepheshe.
Ukwakheka, ifomu lokukhulula
Ngaphezu kwe-glycidone yento, eyisithako esiyinhloko somuthi, iqukethe izinto ezinjengalezi:
- isitashi sommbila;
- i-lactose monohydrate;
- i-magnesium stereate, njll.
Umuthi ukhiqizwa ngendlela yamathebulethi wokuphatha kwangaphakathi. Ngamunye wabo uqukethe ama-30 mg we-glycidone. Amathebhulethi ayindilinga futhi amhlophe ngombala. Izingcezu eziyi-10 zithengiswa emabhulashini. Iphakethe lingaqukatha ama-3, 6 noma angu-12.
I-Pharmacology ne-pharmacokinetics
Umuthi usiza ukwehlisa amazinga kashukela. Lo mphumela kungenxa yesenzo se-glycidone kumaseli we-pancreatic beta. Ngenxa yalokhu, i-insulin iqala ukukhiqizwa ngentshiseko, okunomthelela ekujwayekeni kwephrofayili ye-glycemic.
Ukufakwa kwezakhi zezidakamizwa kwenzeka emgodini wokugaya ukudla. Isenzo somuthi siqala ngemuva kwamahora angu-1-1,5, umsebenzi omkhulu kakhulu ubonakala ngemuva kwamahora ama-2-3 ngemuva kokuphatha. Isikhathi sokudalulwa cishe singamahora ayi-8. Izinso namathumbu ziwususa emzimbeni.
Izinkomba kanye ne-contraindication
Kufanele sisebenzise lesi sidakamizwa kuphela uma kunokuxilongwa okufanele. Kunoma yikuphi okunye, umuthi ungalimaza isiguli. IGlycvidone kufanele isetshenziselwe uhlobo 2 sikashukela. Kubekwa njengengxenye yokwelapha okuyinkimbinkimbi noma njengethuluzi elihlukile.
Kwenqatshelwe ukusebenzisa umuthi lapho kukhona ama-contraindication.
Lokhu kufaka phakathi:
- ukungabekezeleli ekwakhekeni;
- isifo sikashukela sikashukela kanye ne-prekom;
- i-acidosis;
- ketoacidosis;
- Uhlobo 1 isifo sikashukela;
- ukukhulelwa
- ukondla kwemvelo;
- iminyaka yezingane.
Ezimweni ezinjalo, odokotela banquma izidakamizwa ngethonya elifanayo, kepha alinqatshelwe ngenxa yezici ezifakiwe.
Ividiyo evela kusazi:
Imiyalo yokusebenzisa
Ukusetshenziswa kwesidakamizwa kwenziwa ngokuya ngemiyalo. I-Glycvidone iphathwa ngomlomo, mhlawumbe ngokudla.
Inani lemithi linqunywa uchwepheshe ngokuya ngesithombe somtholampilo, izici eziqondene nesiguli, i-concomitant pathologies, njll. Kunzima ukunquma ngokuzimela umthamo ophelele, ngoba ungahluka kusuka ku-15 kuye ku-120 mg ngosuku.
Umthamo onqunywe udokotela ungathathwa ngesikhathi noma uhlukaniswe ngemithamo eminingana - lokhu kuya ngokuthandwa yisiguli.
Umthamo omkhulu akufanele udlule, ngoba kuyingozi ngokuvela kwesimo se-hypoglycemic noma ukwanda kwezimpawu eziseceleni.
Iziguli Ezikhethekile Nezinkomba
Iziguli ezisebenza imithetho ethile zibandakanya:
- Abesifazane abakhulelwe. Ekuqhubekeni kwezifundo, akuzange kusungulwe ukuthi ingxenye esebenzayo ingena kwi-placenta, ngenxa yalokho, akwaziwa ukuthi i-glycidone ingayithinta yini inkathi yokukhulelwa. Mayelana nalokhu, lezi zibhebhe azinqunyelwe omama abakhulelwe.
- Omama abahlengikazi. Imininingwane ngemiphumela yento esetshenziswayo yekhwalithi yobisi lwebele nayo ayikho. Lokhu kusho ukuthi akufanele usebenzise umuthi ngesikhathi sokukhulelwa.
- Izingane nentsha. Ukusebenza nokuphepha komuthi kwalesi sigaba seziguli akuzange kusaphenywa. Ukuvimbela ubunzima obunokwenzeka, ochwepheshe abayinqumeli uGlycvidon kwabanesifo sikashukela esingaphansi kweminyaka yobuningi.
- Abantu abadala. Uma kungekho ukugula okungathí sina, ukusetshenziswa komuthi kuvunyelwe. Uma isiguli sinezinkinga ngesibindi, inhliziyo noma izinso, khona-ke kungadingeka ushintsho ohlelweni lokwelapha.
- Iziguli ezinesifo sezinso. Iningi lezidakamizwa ze-hypoglycemic zivezwa yizinso, ngakho-ke, uma wephula umthetho ekusebenzeni kwawo, kuncishiswa umthamo. IGlycvidone ikhishwa amathumbu, izinso cishe azithinteki kule nqubo, ngakho-ke asikho isidingo sokushintsha umthamo.
- Abantu abanesibindi sokusebenza kwesibindi. Umuthi lo uthinta isibindi. Futhi kulo mzimba umzimba wezinto ezisebenzayo. Kulokhu, ukuba khona kwe-pathologies yesibindi kudinga ukuqaphela lapho usebenzisa i-Glycvidon. Kwezinye izimo, ukusetshenziswa kwayo kwenqatshelwe, yize uvame kakhulu ukunciphisa ingxenye yomuthi.
Ungakhuphula ukusebenza kwesidakamizwa ngosizo lokudla nokuzivocavoca umzimba. Kokubili lokho, nokunye kukhuthaza ukusetshenziswa okusheshayo kwe-glucose yisitho, ngenxa yokuthi kungenzeka ukuthi ungasebenzisi imithamo emikhulu kakhulu yomuthi.
Imiphumela emibi, ukweqisa
Ukuvela kwemiphumela emibi kuvame ukubangelwa ukwephulwa kwemiyalo - ukwandisa umthamo noma ukuphuza amaphilisi, naphezu kokuphambana.
Imvamisa, iziguli zikhononda ngalokhu kuphambuka okulandelayo:
- i-hypoglycemia;
- isicanucanu
- ikhanda
- ukwehla kwesifiso sokudla;
- ukuluma esikhunjeni;
- imishayo.
Ukwelashwa kwezimpawu kusiza ukuqeda ukubonakaliswa kwe-pathological. Ezinye zazo ziqedwa ngokwazo ngemuva kokuhoxiswa kwezidakamizwa. Ngakho-ke, uma zitholakala, kuyadingeka ukubonisana nodokotela wakho.
Ukudlula umthamo kungadala isimo se-hypoglycemic. Umgomo wokuqedwa kwawo kuncike ebukhali bawo. Kwesinye isikhathi kwanele ukudla umkhiqizo oqukethe i-carbohydrate. Kwezinye izimo, kudingeka usizo lochwepheshe oluphuthumayo.
Ukuxhumana neminye imithi
Ukusetshenziswa kanyekanye kweGlycvidone kanye nezinye izidakamizwa kungaholela ekuphambukeni kwesenzo sayo. Kwesinye isikhathi ithonya lawo liyanda, ngenxa yokuthi kukhona ubungozi be-hypoglycemia. Kwezinye izimo, kwenzeka okuphambene, bese ukwelashwa nomuthi kungasebenzi.
Yehlisa umthamo we-glycidone kufanele lapho usetshenziswe ngokuhambisana:
- ama-sulfonamides;
- okokugcobisa;
- ama-salicylates;
- Mao inhibitors.
Ukwenza buthaka umphumela womuthi unga:
- ama-corticosteroids;
- i-nicotinic acid;
- izidakamizwa ze-hormonal.
Ukuze ugweme imiphumela emibi, kubalulekile ukuthi unake yonke imishanguzo ethathwa yisiguli bese ulungisa umthamo ngokufanele. Isiguli kufanele siqiniseke ukwazisa udokotela nganoma imuphi umuthi osetshenzisiwe.
Ama-Analog
Ukusetshenziswa kwamathebulethi okukhulunywa ngawo kwesinye isikhathi kuyenqatshelwe ngenxa ye-contraindication. Ngenxa yalokhu, isiguli kuzodingeka sisebenzise umuthi we-analog.
Ingakhethwa kokulandelayo, okufanayo nesenzo seGlycvidon, izidakamizwa:
- I-Glucophage;
- I-Metformin;
- I-Glurenorm;
- Siofor;
- Amaril.
Isiguli akufanele sibuyisele umuthi obekelwe yena, ngoba zonke izidakamizwa zinezimpawu zazo.
Lokhu kungaholela ezinkingeni uma kukhona ama-contraindication. Ngaphezu kwalokho, ngaphandle kochwepheshe kunzima ukunquma umthamo ofanele. Uma kunesidingo esinjalo, kufanele ubone udokotela.
I-Glycvidone ingathengwa cishe kunoma iyiphi ikhemisi usebenzisa incwadi kadokotela. Izindleko zayo ziyahlukahluka ngokuya ngesifunda esithengiswayo nenani lamathebulethi amaphakethe. Intengo ye-Glycvidone incike kumthamo wento esebenzayo futhi isukela kuma-ruble angama-350 kuye kwangama-700.