I-Amoxicillin 875 yi-ejenti ebanzi ye-antimicrobial ejenti esetshenziselwa izifo ezithathelwanayo zezitho ezahlukahlukene. Kungokweqembu lama-beta-lactam antibiotics (penicillins, cephalosporins).
Igama Lezwe elingafanele
I-Amoxicillin (ngesiLatin Amoxicillin).
I-Amoxicillin 875 yi-ejenti ebanzi ye-antimicrobial ejenti esetshenziselwa izifo ezithathelwanayo zezitho ezahlukahlukene.
I-ATX
J01CA04.
Khipha amafomu nokwakheka
Amathebulethi embozwe ngefilimu aqukethe i-amoxicillin trihydrate 875 mg nosawoti we-potassium we-clavulanic acid 125 mg.
Isenzo se-Pharmacological
I-beta-lactam antibiotic eqenjini le-penicillin lihlanganiswe ne-beta-lactamase inhibitor.
I-Pharmacokinetics
Umphumela we-antimicrobial wesidakamizwa wenziwa ngokuvimba ukwakheka kwe-peptidoglycan - isakhi sokuhlanganiswa kwesitho se-cell membrane, okuholela ekufeni kwama-microorganisms. Amanye ama-bacteria secrete beta-lactamase enzymes, anikezela ukumelana ekwelashweni.
Umuthi uyasebenza uma uqhathaniswa ne-streptococci.
I-Clavulanic acid inactivates beta-lactamases, okuholela esenzweni esisebenzayo somuthi kumabhaktheriya amelana nokwanda kobubanzi bawo bomsebenzi.
Umuthi uyasebenza ngokulwa neStaphylococcus aureus golide ne-epidermal, i-streptococci, i-pneumococcus, i-enterobacteria, i-Escherichia coli, Klebsiella, Corynebacteria, Clostridia, Peptococcus, Neisseria, Legionella, Salmonella, Chlamydia, Treponema.
Izinkomba zokusetshenziswa
Ipheshana lokuphefumula: ukuvuvukala okunamandla kwendlebe ephakathi, ama-craneal sinus, i-tonsillitis, i-pharyngitis, inyumoniya, i-bronchitis.
Ipheshana lesisu: i-typhoid fever, i-enteritis kanye nezinye izifo ze-salmonella, isifo sohudo, isifo sohudo se-etiology yamagciwane, i-peritonitis, i-cholecystitis, i-cholangitis, izilonda ezigugayo nezilonda (njengengxenye yokwelashwa kokuqeda).
Isikhumba: ama-erysipelas, ama-impetigo, ama-dermatoses omsuka wegciwane.
Isistimu ye-genitourinary: i-urethritis, i-cystitis, izifo ezithathelwanayo zezitho zangasese zowesifazane, ukutheleleka nge-gonococcal, chlamydia.
Okunye: i-leptospirosis, i-listeriosis, i-septicemia, i-bacterial meningitis, isifo seLyme, ukutheleleka kokulimala kwe-postoperative, izinkinga ze-odontogenic.
Contraindication
Ukusetshenziswa kwomuthi akunconyelwe kulezi zimo ezilandelayo:
- i-hypersensitivity yomuntu ngamunye ezingxenyeni zomuthi, ezinye izidakamizwa ze-antibacterial ezivela eqenjini le-beta-lactam;
- cholestasis, ukungasebenzi kwesibindi ngomlando wokuthatha umuthi;
- mononucleosis esithathelwanayo.
Ngokuqapha, kungenzeka ukusebenzisa nge-pseudomembranous colitis ngokumelene nesizinda sokwelashwa kwe-antimicrobial ku-anamnesis, ukungasebenzi kahle kwe-renal kanye ne-hepatic, ngesikhathi sokukhulelwa nokuqunjelwa.
Ungayithatha kanjani i-Amoxicillin 875
Umthamo, uhlelo kanye nemvamisa yokuphatha kusethwa ngokuhlukile. Ngaphambi kokusebenzisa, kufanele ubonane nodokotela futhi ufunde imiyalo.
Abantu abadala nezingane ezinesisindo esingaphezu kwamakhilogremu angama-40: i-1 ithebhulethi izikhathi ezi-2 ngosuku ekuqaleni kokudla kwezinsuku ezingama-5-14.
Izingane ezinesisindo esingaphansi kwama-40 kg: 40 mg / kg / ngosuku, zihlukaniswe ngemithamo emithathu.
Ngoshukela
I-Amoxicillin ayithinti ushukela wegazi, ngakho-ke kungaba umuthi wokukhetha ezigulini ezinesifo sikashukela.
Ngaphambi kokuqala ukusetshenziswa, kubalulekile ukuhlola isinxephezelo se-carbohydrate metabolism, isilinganiso se-glomerular filtration rate.
Imiphumela emibi
Isistimu yezinzwa esembusweni: isasasa, ukuphazamiseka kokulala, ukwazi okwenziwe ngombala, izinguquko ekushintsheni kokuziphatha, ikhanda, isiyezi, ukwehluleka.
Kusuka kwizitho ze-hematopoietic: i-anemia, ukwehla kwenani lamaplatelet, amaseli amhlophe egazi, ama-neutrophils, ama-granulocytes, ukwanda kwenani lama-eosinophils.
Amapheshana wesisu
Ukwehla kwesisindo, ukuphazamiseka komzimba, ubuhlungu be-epigastric, ukugcwala kolwelwesi kanye nolimi, ukuvela kwe-enamel yezinyo, i-enterocolitis, i-pseudomembranous colitis, ukungasebenzi kahle kwe-hepatic ngomsebenzi owengeziwe we-enzyme yesibindi ne-bilirubin, jaundice, ne-dysbiosis.
Kusuka ohlelweni lwezinhliziyo
I-Vasculitis, i-palpitations, i-tachycardia.
Engxenyeni yesistimu yenhliziyo, ukuthatha i-Amoxicillin kungadala i-tachycardia.
Allergies
Ukusabela kwe-Hypersensitivity, ukulunywa kwesikhumba, ukuqubha njenge-urticaria ne-erythema, i-edema kaQuincke, ukwethuka kwe-anaphylactic, isifo sikaLyell.
Umthelela ekhonweni lokulawula izindlela
Ayikho imininingwane ngomthelela wokushayela. Ngesikhathi sokwelashwa, umuntu kufanele ayeke imisebenzi edinga ukunakwa okwengeziwe.
Imiyalo ekhethekile
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Kubekiwe uma inzuzo engaba khona kumama idlula ubungozi obungahle bube nomphumela ongemuhle kuzingane.
Kusetshenziswa ngokucophelela ngesikhathi sokuncelisa ibele.
Ungayinikeza kanjani i-Amoxicillin ezinganeni ezingama-875
Ezinganeni, kungenzeka ukusebenzisa umuthi ngendlela yokumiswa noma i-powder izikhathi ezi-3-4 ngosuku.
Umthamo omkhulu wansuku zonke ubalwa ngokuhambisana nesisindo sengane: 40 mg / kg / ngosuku.
Sebenzisa ebudaleni
Sebenzisa ngokuqapha ekwelapheni iziguli ezingaphezulu kweminyaka engama-80.
Ekwelashweni kweziguli ezingaphezu kweminyaka engama-80 ubudala, i-amoxicillin kufanele isetshenziswe ngokuqapha.
Isicelo sokusebenza kokulimala kwezinso
Ngokuthola imvume kwe-creatinine enkulu kune-30 ml / min, ukulungiswa kwamthamo akudingeki.
Ukwehluleka kwezinso nge-glomerular filtration rate ye-10-30 ml / min, umthamo wehla ufike kuma-500 + 125 mg izikhathi ezi-2 ngosuku, ngaphansi kuka-10 ml / min - isikhathi esingu-1 ngosuku.
Nge-hemodialysis, umuthi uthathwa ngesikhathi senqubo.
Ukweqisa
Isimo somtholampilo: i-dyspepsia, Ubuhlungu besisu, ukuqaqanjelwa, ukuphazamiseka kokulala, izidumbu, ikhanda.
Amaqhinga okwelapha ngokweqile: ukugcwala kwesisu, ukuqashwa kwama-adsorbents.
Ukuxhumana nezinye izidakamizwa
Ama-antacid, i-glucosamine, i-chondroitin, ama-laxatives, ama-antibiotics avela eqenjini le-aminoglycoside anciphisa izinga lokufakwa, ivithamini C isheshisa ukufakwa kwe-amoxicillin.
Ama-diuretics, i-allopurinol, izidakamizwa ezingezona ze-steroidal ezilwa nokuvuvukala zandisa amazinga e-plasma egazi.
Ngokusetshenziswa kanyekanye, ubuthi be-methotrexate buyanda.
Vitamin C isheshisa ukumuncwa kwe-amoxicillin.
Ukuhambisana nama-anticoagulants (warfarin, dicumarin) kudinga ukuqapha ngokucophelela i-INR (ingozi eyengeziwe yokopha).
Akufanele ihlanganiswe ne-rifampicin, i-macrolides, i-tetracycline, ama-sulfonamides ngenxa yokwehla kwamandla ekusebenzeni.
Yehlisa umphumela wokuvimbela inzalo ngomlomo.
Ukuhambisana notshwala
Ukuphuza utshwala ngesikhathi sokwelashwa kunganciphisa ukusebenza kwe-antimicrobial therapy.
Ama-Analog
Amagama okuhweba: Flemoxin Solutab, Hiconcil, Amosin, Ecobol, Grunomok, Gonoform, Danemoks, Ospamox.
Abanye: i-Azithromycin, i-Erythromycin, i-Gentamicin, i-Tetracycline.
Izimo zeholide Amoxicillin 875 kusuka ekhemisi
Ikhishwa embhalweni kadokotela obhalwe ngesiLatini ngesiginesha yomuntu siqu nangophawu lukadokotela.
Ngingakwazi ukuthenga ngaphandle kadokotela
Umuthi kadokotela.
Intengo ye-Amoxicillin 875
Ithebhulethi 875 + 125 mg 14 ama-PC. kubiza kusuka kuma-ruble angama-393 kuya kwangama-444. ukupakisha.
Izimo zokugcina zomuthi
Endaweni eyomile engenakufinyeleleka ezinganeni emazingeni okushisa asekamelweni.
Isikhathi sokuphelelwa yisikhathi
Iminyaka engu-2 kusukela ngosuku lokukhiqizwa.
Umkhiqizi Amoxicillin 875
Lek dd IVerovshkova 57, iLjubljana, iSlovenia.
Ukubuyekezwa kwe-Amoxicillin 875
Kurbanismailov R.G., Therapist, Krasnoyarsk
Umuthi omuhle kakhulu wokulwa namagciwane, osetshenziswa odokotela abaningi e-Russian Federation, unezakhi eziningi zofuzo. Umuthi usetshenziswa kabanzi kwezokulolonga izibeletho.
I-Pigareva A.V., i-Therapist, iKrasnodar
Ibanga lesenzo lilinganiselwe, ngakho-ke angikhethi kaningi. Kulula ukuyisebenzisa, ivunyelwe ukusetshenziswa ezinganeni.
USvetlana, oneminyaka engama-34 ubudala, u-Irkutsk
Udokotela wethu wezingane wasendaweni uvame ukunquma le antibiotic. Ilungele izingane zami, ayikho imiphumela emibi. Isicanucanu, ukuhlanza nokuhudula akuzange kubonwe ngemuva kokusebenzisa lesi sidakamizwa.
U-Ivan, oneminyaka engama-29, uSamara
Ngiphuza umuthi kaningi, ngoba Ngihlushwa ukuvuvukala okungapheli kwama-tonsils. Ngingasho ukuthi anginayo imiphumela emibi evela kumaphilisi, ngiyawabekezelela ngokujwayelekile, cishe nawo awanawo umthelela ku-microflora yamathumbu, futhi iyasiza ngokushesha nangendlela efanele. Intengo iyamukeleka futhi, akunangqondo ukuthenga uhlobo olubiza kakhulu lwama-antibiotics.
