I-Flemoklav Solutab 875 iyi-antibiotic yochungechunge lwe-penicillin. Inobubanzi besenzo maqondana nama-microorganisms we-pathogenic. Kuqukethe i-beta-lactamase inhibitor, enomthelela ekwandeni komphumela we-antimicrobial.
Igama Lezwe elingafanele
INN - Flemoklav Solutab: amoxicillin + clavulanic acid.
I-Flemoklav Solutab 875 iyi-antibiotic yochungechunge lwe-penicillin.
I-ATX
Ikhodi ye-ATX: J01CR02.
Khipha amafomu nokwakheka
I-Flemoklav Solutab iyatholakala ngesimo samathebulethi a-allong ahlakazeka umbala ophuzi noma omhlophe anama-inclusions ansundu, ngaphandle komugqa ohlukanisayo. Kuthebhulethi ngayinye kukhona okumaka "421", "422", "424" noma "425" ne-logo yenkampani. Ukwelashwa kwezingane, amaphilisi angahlakazwa kuketshezi ukuze kwakheke ukumiswa okungahambi kahle.
Izinto eziyinhloko ezisebenzayo: i-amoxicillin ne-clavulanic acid, ngesimo se-amoxicillin trihydrate ne-potasium clavulanate. Amathebhulethi ayi-875 kanye ne-125 mg atholakala abhalwe "425". Amakhompiyutha angeziwe: i-crospovidone, ukunambitheka kwe-apricot, i-microcrystalline cellulose, i-magnesium stearate, vanillin, saccharin.
Kuthengiswe ngamabhisikidi ama-7 ama-pcs., Kwiphakethe lamakhadibhodi kukhona ama-2 blims anjalo.
Isenzo se-Pharmacological
Umuthi olwa namagciwane usasebenza ngokulwa namagciwane amaningi angenawo i-gram-negative ne-gram. Kepha njengoba i-amooticillin ibhujiswa yi-lactamases, ayibonisi umsebenzi kumagciwane angakhiqiza le enzyme.
Umuthi olwa namagciwane usasebenza ngokulwa namagciwane amaningi angenawo i-gram-negative ne-gram.
I-Clavulanic acid inhibits-beta-lactamases enolaka, ngesakhiwo sayo iyafana nama-penicillin amaningi. Ngakho-ke, i-spectrum yesenzo somuthi ifinyelela kuma-lactamases we-chromosomal.
Ngenxa yemiphumela ehlanganisiwe yezinto ezisebenzayo, izakhiwo ze-antibacterial zomuthi ziyanda.
I-Pharmacokinetics
Izinto ezisebenzayo zimunwa kahle zivela emgodini wokugaya ukudla. I-Absorption ithuthuka ngomuthi ngaphambi kokudla. Okuqukethwe kwe-plasma ephezulu kakhulu kugcinwa ihora nesigamu ngemuva kokuthatha umuthi. Metabolism kwenzeka esibindini. Umuthi udotshwa ngokuhlunga kwe-renal ngendlela yama-metabolites amakhulu. Isikhathi sokuhoxisa asidluli amahora angama-6.
Izinkomba zokusetshenziswa
Izinkomba eziqondile zokusetshenziswa kweFlemoklav Solutab yilezi:
- izifo zokuphefumula eziphezulu;
- inyumoniya
- ukwanda kwe-bronchitis engapheli;
- izifo ezingama-pulmonary ezingapheli;
- ukutheleleka kwesikhumba nezicubu ezithambile;
- ukutheleleka okuhlanganayo kanye nethambo;
- cystitis
- i-pyelonephritis;
- ukutheleleka kwezinso nezitho zomchamo.
Umuthi okulinganiselwa ku-875/125 mg ubekelwa ekwelapheni i-osteomyelitis, ukutheleleka kwe-gynecological, kuvame ukusetshenziswa kuma-obstetrics.
Contraindication
Kunezimo eziningana lapho ukuthatha i-antibiotic kuphikiswe ngokuphelele:
- jaundice
- ukungasebenzi kwesibindi;
- i-mononucleosis esithathelwanayo;
- i-lymphocytic leukemia;
- i-hypersensitivity kuma-penicillin nama-cephalosporins;
- hypersensitivity kuzakhi zomuthi;
- umsebenzi wezinso ongonakalisiwe;
- iminyaka efinyelela eminyakeni eyi-12;
- isisindo somzimba kuze kufike ku-40 kg.
Ngokunakekela
Ngokuqapha, umuthi ubekelwe abantu abanokuhluleka kakhulu kwezinhlungu ze-hepatic futhi ezingamahlalakhona, ngaphezu kwalokho, ezigulini ezinokulimala kokusebenza kwesisu. Kwi-trimester yokuqala yokukhulelwa, i-Flemoklav ingathathwa kuphela ngokuya ngenkomba eqinile.
Kwi-trimester yokuqala yokukhulelwa, i-Flemoklav ingathathwa kuphela ngokuya ngenkomba eqinile.
Ungayithatha kanjani iFlemoklav Solutab 875
Izibhebhe zithathwa ngomlomo ngaphambi kokudla main. Sebenzisa wonke noma uncibilike emanzini. Phuza uketshezi oluningi. Kubantu abadala, umthamo ungu-1000 mg kabili ngosuku njalo emahoreni ayi-12. Ukwelashwa kwezifo ezingalapheki noma ezinzima, i-625 mg yesidakamizwa ichazwa kathathu ngosuku njalo ngamahora ayi-8. Uma kunesidingo, ungayiphinda kabili idosi ebekiwe ekuqaleni.
Ngabe isifo sikashukela siyenzeka?
Izithako ezisebenzayo azithinti izinguquko ekugxileni kweglue glucose. Ngakho-ke, ukuthatha umuthi wesifo sikashukela kungenzeka. Kepha kulokhu, ukusebenza kwomuthi kuncishiswa kancane, ngakho-ke inkambo yokwelashwa izoba yinde.
Imiphumela emibi
Ngokusebenzisa isikhathi eside noma izifundo eziphindaphindwe kaningi zokwelapha, izimpawu ezingemnandi zingavela ezithweni ezithile nasezinhlelweni ezithile. Mhlawumbe ukuthuthukiswa kwe-fungal kanye ne-bacterial superinitness.
I-Flemoklav Solutab 875 ingadala ubuhlungu besisu.
Amapheshana wesisu
Ukugaya ukudla kuthinteka kakhulu. Imiphumela emibi ibonakaliswa ngendlela: isicanucanu, kwesinye isikhathi ukugabha, ukuthamba, Ubuhlungu besisu, uhudo, i-pseudomembranous colitis, ezimweni ezingatheni, i-matumbo candidiasis kanye nokuvela kokuxubha kwensimbi enamel.
Izitho zeHematopoietic
Ukusuka ohlelweni lokujikeleza, ukuvela kwenzeka ngokuqabukela kakhulu: i-hemolytic anemia, i-thrombocytosis, i-leukopenia, i-granulocytopenia, ukwanda kwesikhathi se-prothrombin, kanye nokwenza kwegazi.
Isistimu yezinzwa ephakathi
Isistimu yezinzwa nayo ihlushwa ukuthatha i-antibiotic. Kungabonakala: ikhanda, isiyezi, ukuhlaselwa okukhokhisayo, ukuqwasha, ukukhathazeka, ukuhlukunyezwa, ukungazi kahle.
Kusuka ohlelweni lomchamo
Kwesinye isikhathi izinqubo zokuvuvukala ziyabonakala.
Umuthi okukhulunywa ngawo ungavusa ukubonakala kokuqhuma kwesikhumba, kuhambisane nokulunywa kanzima.
Allergies
Ukusabela kwe-allergic kuvamile: ukuqubuka kwesikhumba okuhambisana nokulunywa kanzima, i-urticaria, umkhuhlane wezidakamizwa, isifo sokuqina kwesikhumba, isifo seStevens-Johnson, i-erythema multiforme, i-eosinophilia, i-edema ye-laryngeal edema, nephritis, vasculitis.
Imiyalo ekhethekile
Ngaphambi kokuqala ukulwa nalesi sifo, kufanele kubhekwe ngaphambi komlando wokuvela kwezakhi zomuthi. Ukunciphisa umphumela onobuthi, kungcono ukuphuza umuthi ngaphambi kokudla. Lapho ufinyelela amandla amakhulu, kufanele ukhansele ukwamukela umuthi. Lapho kulwelwa izifo ezingamahlalakhona, umthamo uphindwe kabili, kepha lonke ushintsho ekusebenzeni kwezinso nesibindi kumele lubhekwe.
Ukuhambisana notshwala
Ungahlanganisi notshwala. Ukusebenza kokusetshenziswa kwe-antibiotic kuncishisiwe, futhi umthelela wazo ogayweni wokugaya ukudla kanye nohlelo lwezinzwa oluphakathi luyanda kuphela.
Umthelela ekhonweni lokulawula izindlela
Njengoba umuthi unomphumela oqondile ohlelweni lwezinzwa oluphakathi, kungcono ukuyeka ukushayela. Ukunakwa kungathikamezeka futhi ijubane lokuphendula kwe-psychomotor okudingekile ezimweni eziphuthumayo lingashintsha.
Njengoba umuthi unomphumela oqondile ohlelweni lwezinzwa oluphakathi, kungcono ukuyeka ukushayela.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Ucwaningo luye lwabonisa ukuthi umuthi awunawo umphumela we-teratogenic ku-fetus. Kepha esimweni sokuzalwa ngaphambi kwesikhathi, i-necrotic enterocolitis kosanda kuzalwa ingakhula. Ngakho-ke, akufanelekile ukuphuza umuthi ngesikhathi sokukhulelwa.
Izinto ezisebenzayo zingena kubisi lwebele, okucasulayo ukuqunjelwa kanye nokuvela kwe-candidiasis yomgodi womlomo enganeni. Ngakho-ke, ngesikhathi sokwelashwa, kuyalulekwa ukwenqaba ukuncelisa ibele.
Ungazinikeza kanjani izingane iFlemoklav Solutab eziyi-875
Umthamo wezingane kusuka ezinyangeni ezi-3 kuya eminyakeni emi-2 uyithebulethi eyi-125 mg izikhathi ezi-2 ngosuku. Ezinganeni kusuka eminyakeni emi-2 kuya kwengama-7, umthamo onjalo ubekwa kathathu ngosuku. Ezinganeni ezisukela eminyakeni eyisikhombisa kuya kwengu-12, umthamo uphindwe kabili futhi umuthi nawo uphuzwa kathathu ngosuku.
Umthamo ekugugeni
Ukulungiswa komthamo akudingekile futhi kusuka ku-625 kuya ku-100 mg wesidakamizwa ngosuku.
Ukulungiswa komthamo wesidakamizwa ekugugeni akudingekile futhi kusuka ku-625 kuya ku-100 mg wesidakamizwa ngosuku.
Isicelo sokusebenza kokulimala kwezinso
Konke kuzoncika ekuthini imvume ye-creatinine. Lapho iphakama, yehlisa umthamo we-antibiotic obekelwe isiguli.
Sebenzisa umsebenzi wesibindi okhubazekile
Ukwephulwa okukhulu komsebenzi wesibindi, ukusetshenziswa kwalesi sidakamizwa akunconywa. Ngokwezinga eliphansi lokwehluleka kwesibindi, kunconywa umthamo omncane osebenza kahle.
Ukweqisa
I-overdose ye-Flemoklav Solutab ibonakaliswa ukwephula ipheshana esiswini nokulinganisela kwe-electrolyte yamanzi. Kwesinye isikhathi, ngokumelene nesizinda sokusetshenziswa isikhathi eside, i-crystalluria ingakhula, okungavusa ukwehluleka kwezinso. Ezigulini ezinoshintsho ekusebenzeni kwezinso, kungenzeka ukwanda kwe-convulsive syndrome.
Ukwelashwa kuzoba uphawu futhi kuhloswe ngalo ukubuyisa ibhalansi elenziwa ngamanzi-electrolyte. Umuthi udlulwa yi-hemodialysis.
Uma kwenzeka okweqile kweFlemoklav Solutab 875, i-hemodialysis iyadingeka.
Ukuxhumana nezinye izidakamizwa
Ngokuphatha kanyekanye nge-sulfonamides, ukuphikisana kuyaphawulwa. Kwenqatshelwe ukusebenzisa umuthi ngokuhlangana ne-disulfiram. I-Excretion yento esebenzayo iyancipha lapho isetshenziswa nge-phenylbutazone, i-phenenecid, i-indomethacin ne-acetylsalicylic acid. Ngasikhathi sinye, ukuqina kwayo emzimbeni kukhuphuka kakhulu.
Ama-aminoglycosides, ama-glucosamines, ama-antacid nama-laxatives anciphisa izinga lokufakwa kwezakhi ezisebenzayo. I-Ascorbic acid ithuthukisa ukumuncwa kwe-amoxicillin. Uma isetshenziswa nge-Allopurinol, kungenzeka ukuthi kuqhamuke isikhumba. Ukucaciswa kwangempela kwe-methotrexate kuyancipha, umphumela wayo onobuthi uyanda. Ukufakwa kwe-Digoxin kuyanda. Lapho isetshenziswa ngama-anticoagulants angaqondile, ingozi yokopha iyanda. Ukusebenza kwezindlela zokuvimbela inzalo kuncishiswa.
Ama-Analog
Kunezinhlobo eziningi ze-Flemoklav Solutab analogues ezifana ngayo ngokuya ngezinto ezisebenzayo nomphumela wokwelapha. Okuvame kakhulu phakathi kwabo yilezi:
- I-Trifamox IBL;
- I-Amoxiclav 2X;
- Phinda;
- Augmentin;
- Panklav;
- I-Baktoklav;
- I-Medoclave;
- Klava;
- Arlet
- I-Ecoclave;
- ISultasin;
- I-Oxamp;
- I-Oxamp Sodium;
- I-Ampiside.
Izimo zeholide Flemoklava Solutab 875 kusuka kumakhemisi
Ungathenga incwadi kadokotela ekhemisi.
Ngingakwazi ukuthenga ngaphandle kadokotela
Kuphela uma unikezwa incwadi kadokotela ekhethekile evela kudokotela wakho.
Intengo
Izindleko zokupakisha amaphilisi ayi-14 cishe ngama-ruble angama-430-500.
Izimo zokugcina zomuthi
Gcina endaweni eyomile futhi emnyama, kude nezingane nezilwane ezifuywayo, kumazinga okushisa angaphansi kwe- + 25ºС.
Isikhathi sokuphelelwa yisikhathi
Iminyaka engu-2, ungasebenzisi ngemuva kwalesi sikhathi.
Gcina endaweni eyomile futhi emnyama, kude nezingane nezilwane ezifuywayo, kumazinga okushisa angaphansi kwe- + 25ºС.
Umkhiqizi uFlemoklava Solutab 875
Inkampani ekhiqiza: i-Astellas Pharma Europe, B.V., Netherlands.
Ukubuyekezwa Flemoklava Solutab 875
U-Irina, oneminyaka engama-38, eMoscow: "Ngasebenzisa umuthi wokubulala amagciwane ngenkathi ngiphatha i-bronchitis enzima. Ngabona ukuthuthuka osekwenziwe ngosuku 2. Bengidinga nje ukuphuza ama-enzyme amathumbu, nganginobuhlungu obukhulu nokukhungatheka."
UMikhail, oneminyaka engama-42, eSt. Petersburg: "UFlemoklav Solyutab wanqunywa ngemuva kokulimala umlenze wami. Isilonda besisikhulu futhi sivulekile. I-antibiotic isizile. Emiphumeleni emibi, ngikwazi nje ukubona isicanucanu."
UMargarita, oneminyaka engama-25, uYaroslavl: "Ngabona uFlemoklav lapho elapha inyumoniya. Ngaso leso sikhathi ngathatha eminye imishanguzo ukuze ngilinganisele i-microflora yamathumbu nemithi ye-antifungal. I-antibiotic isize ngezinsuku ezingama-3-4. Ngayiphuza izinsuku eziyisikhombisa. Ngigculisekile ngomphumela, imiphumela emibi emningi kuphela. "Isisu sami sibuhlungu, ikhanda lami beligula kakhulu."
U-Andrei, oneminyaka engu-27 ubudala, uNizhny Novgorod: "Ngithathe umphimbo obuhlungu besifo. Ngakho-ke, udokotela wangiyalela ukuthi ngithathe le-antibacteria isonto lonke. Impilo yami yaqala ukuba ngcono ngolwesihlanu: umphimbo wami oqala ukuthamba, i-plaque ihambile, izinga lokushisa lehla. Ngokuhambisana nomuthi, ezinye izidakamizwa zachazelwa ukwenza amathumbu ajwayelekile microflora, ngakho-ke akubanga nazimpawu ezibonakalayo ezimbi ngendlela yokucasulwa yisisu. "
