Umuthi Kefsepim: imiyalelo yokusetshenziswa

I-Kefsepim yenzelwe ukwelashwa kwezifo ezibangelwa izifo. Isetshenziselwa ukuphathwa kwe-intravenous and intramuscular.

Igama Lezwe elingafanele

Isikhathi sasekuseni.

I-Kefsepim yenzelwe ukwelashwa kwezifo ezibangelwa izifo.

I-ATX

J01DE01.

Khipha amafomu nokwakheka

Kukhululwa njengempuphu ukuthola isisombululo sokuphathwa kwe-intravenous and intramuscular. Isithako esisebenzayo yi-cefepime (500 noma 1000 mg kwibhodlela elingu-1).

Isenzo se-Pharmacological

Le yi-ejenti elwa namagciwane eqenjini lama-cephalosporins. Inomsebenzi obanzi maqondana nezinhlobo ezahlukahlukene zamagciwane amelana nemithi ejwayelekile ye-antibacterial. Unqabe ekonakalisweni yi-beta-lactamases. Ingena kalula kumaseli wamagciwane.

Isebenza ngokulwa nama-anaerobes, izingqinamba zeSrerecccus pyogene, i-enterobacteria, i-Escherichia, iKlebsiella, iProteus mirabilis, i-pseudomonas.

Izinhlobo ezinhlobonhlobo zama-enterococci, ama-staphylococci amelana ne-methicillin, ama-clostridia awazweli ku-antibiotic.

I-Pharmacokinetics

Ukuqoqwa okuphezulu kakhulu kwengxenye yokwelapha ku-plasma kutholakala ngemuva kwengxenye yehora futhi kuhlale amahora ayi-12. Ukuqedwa kwesigamu sempilo kwenzeka kusuka emahoreni amathathu kuya kwayi-9.

Kuqhuma umchamo, i-bile, umakhenikha we-bronchial, i-prostate.

I-Kefsepim isetshenziselwa ukwelapha i-pathologies yesibeleko sesisu esibangelwa amagciwane.

I-Kefsepim isetshenziselwa ukwelapha i-pyelonephritis.

I-Kefsepim ikhonjiswa ngokulinganisela kuya kubunyeni obukhulu be-pneumonia.

Umuthi usetshenziselwa ukwelapha ukutheleleka kwezifo zomgudu womchamo obangelwa amagciwane.

Izinkomba zokusetshenziswa

Kuboniswa ezimweni ezinjalo:

1. Uhlobo oluphakathi nolubucayi bezinduna olubangelwa izingqinamba ze-Streptococcus streptococcus pneumoniae, Pseudomonas aeruginosa, Klebsiella noma izinhlobo ezahlukahlukene ze-Enterobacteria.
2. I-Febrile neutropenia (njengokwelapha okunamandla).
3. Ukutheleleka kwezifo ze-urinary (ngokwehlukahluka kwamazinga enkimbinkimbi) okubangelwa amagciwane i-Staphylococcus aureus ne-Streptococcus pyogene.
4. I-Pyelonephritis.
5. I-Pathologies ye-patity esiswini ebangelwa amagciwane - i-Escherichia, Klebsiella, pseudomonads futhi ikakhulukazi i-Enterobacter spp.
6. Ukuvimbela ukutheleleka ngesikhathi sokuhlinzwa okuhlukahlukene ezithweni zesisu.

Contraindication

Lo muthi uphethwe ku-:

1. I-Hypersensitivity yomzimba kuya ku-cefazolin, ama-cephalosporin antibiotic, amalungiselelo e-penicillin, izidakamizwa ze-beta-lactam, i-L-arginine.
2. Ubudala bengane bufika ezinyangeni ezi-2 (uma kunesidingo, ukuphathwa okuphathelene nomuthi). Amandla wokwethula i-Kefsepim kulesi sigaba seziguli awafundwanga.

Kwenqatshelwe ukwenza imijovo ye-intramuscular kuze kufike eminyakeni eyi-12.

Ngokunakekela

Ngokucophelela enikezwe abantu abathole i-pathology yegaya yokugaya, ukuthambekela kokungezwani nemithi. Uma kukhona ukungahambi kahle, isidakamizwa sikhanseliwe.

I-Kefsepim ilawulwa ngaphakathi kwegazi njenge-infusion.

Kwenqatshelwe ukwenza imijovo ye-intramuscular ezinganeni ezingaphansi kweminyaka eyi-12.

I-Kefsepim kufanele igxunyekwe kanye ne-lidocaine hydrochloride.

Ungayithatha kanjani iKefsepim

Ihanjiswa ngaphakathi kwethambo njenge-infusion. Isikhathi senqubo asikho ngaphansi kwengxenye yehora. Ukuphathwa kwe-intramuscular of the drug kuvunyelwe izinhlobo ezithambile noma ezilinganiselayo zezifo zokuhambisa umchamo. Imithamo incike ohlotsheni lwegciwane, ubukhulu benkambiso yokutheleleka nomsebenzi wezinso.

Umuthi kufanele uhlanganiswe kanye ne-lidocaine hydrochloride.

Kwi-pneumonia: i-1-2 g yesisombululo ifakwa emithanjeni kabili ngosuku ngemvamisa yamahora ayi-12. Isikhathi sokwelashwa siyizinsuku eziyi-10.

Uma kwenzeka ungenwa yigciwane lomchamo: ungene injekweni noma ungumzali ku-500-1000 mg ngemuva kwamahora ayi-12 ngezinsuku eziyi-7-10.

Uma kwenzeka izifo ezithambile zesikhumba nezicubu ezithambile: 2 g yemithi ifakwa emthanjeni imvamisa yamahora ayi-12. Isikhathi sokwelashwa siyizinsuku eziyi-10. Umthamo ofanayo kanye nesikhathi sokuphatha umuthi sisetshenziselwa izifo ezithinta isisu.

Ukuvimbela ukutheleleka ngesikhathi sokuhlinzwa esiswini, i-iv inikezwa ihora ngaphambi kokungenelela. Inani lomuthi liyi-2 g. Isixazululo senqatshelwe ukuthi singasetshenziswa ngasikhathi sinye ne-metronidazole. Uma kunesidingo sokwethula i-metronidazole, khona-ke udinga ukuthatha enye isirinji noma uhlelo lokufaka.

Ezinganeni, umthamo ukhethiwe ngokuya ngesilinganiso sama-50 mg ngekhilogremu ngayinye yesisindo somzimba. Imvamisa yemijovo amahora angama-12, futhi nokwehla kwenani lama-neutrophils - amahora angama-8.

Ekuhlulekeni kwe-renal okungapheli, inani lemithi liyancipha.

Ekuhlulekeni kwe-renal okungapheli, inani lemithi liyancipha.

Kwezinye iziguli, ngemuva kokusebenzisa umuthi, umphimbo obuhlungu ungavela.

I-Kefsepim ingadala ukungaboni kahle kokunambitheka.

Ngemuva kokusebenzisa umuthi, kungavela uhlelo lwe-lupus erythematosus.

Ukuthatha umuthi kungahle kuhambisane ne-rheumatism.

Lapho usebenzisa umuthi, ungahlangabezana nokubonakaliswa okubi okunjengobuhlungu emuva.

Umuthi ungadala ushintsho kumamoya wegazi elebhu.

Ngoshukela

Ukwanda koshukela akuyona inkomba yokwehliswa komthamo.

Imiphumela emibi yeKefsepim

Kungadala imiphumela emibi ehlukahlukene, ikakhulukazi ezigulini ezizwela imishanguzo.

Ezinye iziguli zingathola umphimbo obuhlungu, emuva, indawo yomjovo, ukubona ukunambitheka okulimazayo, nokuqina okubukhali. Ngomjovo we-iv, i-phlebitis ivame ukukhula. Njengomphumela wokuphathwa kwe-i / m, kubuhlungu kakhulu. Akukona ukuthuthuka kweqiniso.

Kusuka ezicutshini zemisipha

Akuvamile: ukubukeka kwe-lupus erythematosus e-systemic, i-rheumatism, ukuvuvukala kwamalunga.

Amapheshana wesisu

Ukuphazamiseka kwendlela yokugaya ukudla kungenzeka, kuboniswe ngesicanucanu, ukuhlanza, ukuqunjelwa noma isifo sohudo. Imvamisa iziguli zikhathazeka ngobuhlungu besisu.

Izimpawu ze-dyspeptic zisuswa kalula ngosizo lwama-probiotic.

Izitho zeHematopoietic

Umuthi ungadala ushintsho kumamoya wegazi welebhu kanye ne-vasodilation.

Isistimu yezinzwa ephakathi

Izilonda ze-CNS ezingaba khona:

• ubuhlungu endaweni yekhanda;
• isiyezi esinzima;
• ukuphazamiseka kokulala ngesimo sokuqwasha ebusuku nobuthongo besikhathi sasemini;
• ukuphazamiseka kwemizwa;
• umuzwa wokukhathazeka okukhulu;
• ukudideka okukhulu;
• ukunakwa okungahambi kahle, inkumbulo nokuhlushwa;
• imisipha yokuqina.

Ngemuva kokusebenzisa umuthi, kuvame ukuvela ikhanda, okuwuphawu lomphumela wecala.

Ukusetshenziswa kwomuthi kungahle kuhambisane nesiyezi.

Umuthi ungadala ukuphazamiseka kokulala ngendlela yokuqwasha ebusuku.

Ngokuphikisana nesizinda sokusetshenziswa kwomuthi, ukuhlaselwa isicanucanu nokuhlanza kungenzeka.

Ngesikhathi sokusebenzisa umuthi, ukuvela okungahambi kahle njengokuqunjelwa noma isifo sohudo kungenzeka.

Imvamisa ngemuva kokusebenzisa i-Kefsepim, iziguli zikhathazeka ngobuhlungu besisu.

I-Kefsepim ingadala imemori ekhubazekile.

Ngokulashwa isikhathi eside ezigulini ezine-pathologies yezinso, ukulimala kobuchopho obukhulu kungenzeka.

Kusuka ohlelweni lomchamo

Kwesinye isikhathi kuholela kumonakalo omkhulu ohlelweni lwe-excretory. Ingabonakala ngokuncipha kwenani lomchamo (kuze kufike ku-anuria).

Kusuka ohlelweni lokuphefumula

Ukulimala ohlelweni lokuphefumula kungenzeka. Iziguli zikhathazekile ngokukhwehlela, umuzwa wokuqina esifubeni kanye nokuphefumula.

Kusuka ohlelweni lwezitho zofuzo

Abesifazane bavame ukuphazanyiswa ukuphuma komzimba kowesifazane kanye nokulunywa kwe-perineum.

Kusuka ohlelweni lwezinhliziyo

Mhlawumbe ukuthuthukiswa kwe-tachycardia, edema.

Allergies

Imiphumela yokungezwani komzimba ibonakala ngesimo se:

• ukuqunjelwa, ikakhulukazi i-erythema;
• umkhuhlane;
• i-anaphylactoid phenomena;
• i-eosinophilia;
• erythema multiforme exudative;
• USteven Johnson syndrome.

Ukusabela okwenziwa isidakamizwa kuziveza ngesimo sokuqhuma.

Umuthi ungadala i-tachycardia.

Ngemuva kokusebenzisa i-Kefsepim, abesifazane bangaphazanyiswa ukukhipha i-vaginal kanye nokulunywa kwe-perineum.

Ngenkathi uphuza umuthi, ukukhwehlela kungenzeka.

Odokotela batusa ukuthi ungashayeli imoto ngesikhathi sokwelashwa kukaKefsepim.

Uma isiguli sakha i-pseudomembranous colitis, ukuphathwa kweKefsepim kuyayeka.

Ngemuva kokusebenzisa umuthi, isiguli singaphazanyiswa ukuphefumula komoya.

Umthelela ekhonweni lokulawula izindlela

Kwezinye izimo, umuthi ungadala ukungaboni kahle, unciphise ukugxila. Ngakho-ke, odokotela batusa ukuthi ungashayeli imoto futhi ungasebenzi ngamasu ayinkimbinkimbi ngesikhathi sokwelashwa.

Imiyalo ekhethekile

Uma isiguli sakha i-pseudomembranous noma i-antipatitis ehambisana ne-antipatitis, isifo sohudo isikhathi eside, khona-ke ukuphathwa kwalo muthi kuyayeka. IVancomycin noma i-metronidazole ihanjiswa ngomlomo.

Sebenzisa ebudaleni

Ngokulimazeka okukhulu kwezinso, ukuncipha komthamo noma ukufakwa kwezidakamizwa kuyadingeka.

Isabelo sezingane

Ayibekelwe izingane ezingaphansi kwezinyanga ezimbili ubudala.

Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba

Sebenzisa isikhathi sokutholwa kuphela lapho umphumela oyifunayo kuwo ungaphezulu kwengozi engaba khona. Kwi-trimester yokuqala ayiqokwa.

I-Kefsepim isetshenziswa ngesikhathi sokukhulelwa lapho umphumela oyifunayo udlula ubungozi obukhona.

Ngesikhathi sokulashwa ngeKefsepim ngesikhathi sokuqunjelwa, ingane idluliselwa ekuondleni okungelona iqiniso.

Ukuphazamiseka kwesibindi okukhulu - okubonisa ukwehlisa umthamo weKefsepim.

I-Kefsepim ayinqunyelwe izingane ezingaphansi kwezinyanga ezimbili ubudala.

Uma kudingekile ukwenza ukwelashwa ngesikhathi sokuncelisa, khona-ke ingane kufanele idluliselwe okwesikhashana ekunikezelweni kokufakelwa okwenziwe ngobuciko.

Isicelo sokusebenza kokulimala kwezinso

Nge-pathology ye-renal, ukuncishiswa komthamo kuyadingeka uma kubhekwa izinga le-creatinine. Kuyadingeka ukubhekisisa njalo okuqukethwe kwento esebenzayo egazini.

Sebenzisa umsebenzi wesibindi okhubazekile

Ukuphazamiseka kwesibindi okukhulu - isibonakaliso sokunciphisa umthamo noma ukulungisa ukwelashwa uma kwenzeka kuguqulwa ushintsho esithombeni segazi.

I-Kefsepim Overdose

Ngokunyuka komthamo, isiguli singase sizwe ukugcwala, ukulimala kobuchopho, ukuvusa imizwa okubucayi kanye nemisipha. Kaningi, lezi zibonakaliso zivela kubantu abanesifo sezinso esinzima.

Ukwelashwa kwe-overdose ezigulini kuhambisana nenqubo ye-hemodialysis kanye nokwelashwa kokulondolozwa kwezimpawu. Ukuthuthukiswa kokuvela okukhulu kokuzwela okungajwayelekile kuyinkomba yokuqokwa kwe-adrenaline.

Ukuxhumana nezinye izidakamizwa

Umuthi awuhlanganisi ne-heparin analogues, amanye ama-antibiotic.

Ama-diuretics akhulisa inani lomuthi egazini futhi abangele nomphumela walo onobuthi ezinsweni. Ukuthatha izidakamizwa ezingezona ze-steroidal ezilwa nokuvuvukala kwandisa ingozi yokopha kakhulu.

I-Kefsipim ayivunyelwe ukuthi isetshenziswe ngokubambisana nezidakamizwa ezingezona ze-steroidal ezilwa nokuvuvukala.

Isixazululo akufanele siphathwe kwisipaki esifanayo nalezi zidakamizwa:

• IVancomycin;
• I-Gentamicin;
• ITobramycin;
• I-Netilmicin.

Yonke imishanguzo ebekwe nge-Kefsepim kufanele iphathwe ngokuhlukile.

Ukuhambisana notshwala

Akuhambisani notshwala.

Ama-Analog

Njengokusetshenziswa kwezidakamizwa esikhundleni:

• Abipimi;
• I-Agicef;
• I-Excipim;
• I-extentsef;
• UMaxinort;
• Maksipim;
• ISeptipim.

Imibandela yekhefu lekhemisi

Ikhishwe ngumbhalo.

Ngingakwazi ukuthenga ngaphandle kadokotela?

Imithi ayitholakali ngaphandle kokuthola umuthi.

Intengo

Izindleko ze-1 g zokwakheka ukuthola isisombululo cishe ngama-ruble angama-170.

Izimo zokugcina zomuthi

Gcina kude nokukhanya nomswakama, kude nezingane.

Isikhathi sokuphelelwa yisikhathi

Ivumelekile iminyaka emi-3 kusukela ngosuku lokukhiqizwa.

Umkhiqizi

I-Oxford Laboratories Pvt. , ENdiya.

Esikhundleni somuthi kungenzeka kube yi-Abipim.

Izikhwanyana ezinendlela efanayo yokwenza izinto zifaka isidakamizwa iMakisipim.

Faka umuthi esikhundleni somuthi onjenge-Extentsef.

Ukubuyekezwa

U-Irina, oneminyaka engu-35, eMoscow: "Ngosizo lweKefsepim, ngelapha i-pneumonia enzima. Ukwelashwa kwenzeke esibhedlela izinsuku eziyi-10. Ngakubekezelela kahle imijovo leyo, yize yayinobuhlungu. Kwakungekho miphumela emibi."

U-Olga, oneminyaka engama-40, u-Ob: "Lesi sidakamizwa sisize ekwelapheni isifo esibuhlungu sohlelo lwe-urinal, olwaluhambisana nobuhlungu nobuhlungu ngesikhathi sokuchama. Ukwelashwa kwakubekezelelwa kahle, kwakungekho miphumela emibi. Ngilandela ukudla kanye nerejimeni yansuku zonke ukuvimbela ukubuyela esimeni."

U-Oleg, oneminyaka engama-32, eSt. Petersburg: Umuthi omuhle owasiza ukubhekana nokuvuvukala kwe-bronchial. Ngenxa yokulimala kwamathambo engapheli, ngibe nokukhwehlela kanzima, okuhamba ngemuva kokudilizwa yiKefsepim. "