I-Tio-Lipon Novofarm ibhekisela kwizimali eziguqula izinqubo ze-metabolic. Umuthi uthinta i-metabolism, ubuyisela i-lipid ne-carbohydrate metabolism. Isiza ukunciphisa i-cholesterol yegazi.
Igama Lezwe elingafanele
INN: I-Thioctic acid.
I-Tio-Lipon Novofarm ibhekisela kwizimali eziguqula izinqubo ze-metabolic.
I-ATX
Ikhodi ye-ATX: A16AX01
Khipha amafomu nokwakheka
Kutholakala ngesimo sokugxiliswa okuhloswe ngaso ukuxazulula ikhambi lokuphatha okulandelayo kwe-intravenous. Ukugxila kuyabonakala, kune-hue eluhlaza okotshani. Into esemqoka esebenza yi-thioctic noma i-lipoic acid. Izingxenye ezengeziwe: i-propylene glycol, i-ethylene diamine namanzi omjovo. Gxila emabhodleleni kukhiqizwa. Izingcezu eziyi-10 kwiphakethe noma emaphaketheni amaseli ama-2 kwikhadibhodi enezinto eziyisi-5 inye
Awekho amaphilisi akhiqizwayo.
Isenzo se-Pharmacological
I-Thioctic acid iyi-antioxidant yemvelaphi yendabuko. Kuthuthukisa ukubopha kwama-radicals mahhala. Le nto yakhiwa ngesikhathi kwe-decarboxylation ye-alpha-keto acid.
Umuthi une-hypolipidemic, hypoglycemic, hypocholesterolemic kanye nemiphumela ye-hepatoprotective.
Umuthi osebenzayo yi-coenzyme yezakhiwo zama-multenzyme ze-mitochondria, futhi ubandakanyeka ngqo ezinqubweni ze-oxidation ze-pyruvic acid. Isiza ukwandisa ukugcwala kwe-glycogen, eyenziwe ngoqoqweni esibindini. Kulokhu, izinga loshukela egazini liyancipha. Lokhu kuholela ekunqobeni ukumelana ne-insulin.
I-Lipoic acid esenzweni sayo ifana namavithamini we-B. Ithatha iqhaza kuma-carbohydrate kanye ne-lipid metabolism, ivuselela i-cholesterol metabolism efanelekile, ithuthukise umsoco we-neurons futhi isize ukusebenza kwesibindi kwezejwayelekile.
Umuthi une-hypolipidemic, hypoglycemic, hypocholesterolemic kanye nemiphumela ye-hepatoprotective.
I-Pharmacokinetics
Ngokuphathwa kwe-intravenous, inani eliphezulu lezinto ezisebenzayo egazini libonakala ngemuva kwemizuzu eyi-10. I-Bioavailability kanye namandla okubopha ezinhlakeni zamaprotheni egazi ziphansi impela. Umuthi udlulwa yizinso ngendlela yama-metabolites amakhulu. Isigamu sempilo sicishe sibe ihora.
Izinkomba zokusetshenziswa
Izinkomba eziqondile zokusebenzisa umuthi yilezi:
- ukuvimbela noma ukwelashwa kwe-polyneuropathy yesifo sikashukela;
- i-alcohol polyneuropathy therapy;
- izifo ezahlukahlukene zesibindi.
Zisetshenziswa ekwelapheni kwezimo zokuphuza umzimba obukhulu komzimba, ngokwesibonelo, ubuthi ngamakhowe, utshwala obusezingeni eliphansi, usawoti wezinsimbi ezisindayo, amakhemikhali.
Contraindication
Ama-contraindication aphelele aqondiswa yimiyalo yile:
- ukungabekezelelani kwe-lactose;
- i-glucose galactose malabsorption;
- ukukhulelwa
- ukuncelisa;
- iminyaka efinyelela eminyakeni eyi-18;
- hypersensitivity kuzakhi zomuthi.
Ngokunakekela
Ngokuqapha nangaphansi kokuqashwa ngudokotela okuqinile, umuthi unqunyelwe ukuthi:
- isifo sikashukela mellitus;
- uphuzo oludakayo.
Umuthi uthathwa ngokucophelela okukhulu uma kwenzeka ukungasebenzi kahle kwezinso nesibindi, njengoba into esebenzayo inamandla okuqongelela esibindini. Uma kukhona ukuwohloka emiphumeleni yokuhlola, ukwelashwa kuyamiswa masinyane. Ukuqapha kuyadingeka nakwabadala basengozini enkulu kakhulu yokuba nezinkinga zenhliziyo.
Umuthi uthathwa ngokucophelela okukhulu uma kungasebenzi kahle izinso nesibindi.
Ungayithatha kanjani iTio-Lipon Novofarm?
Isixazululo siphathwa ngokuhlinzwa. Ngaphambi kokuphatha, ukugxila kufanele kuhlanjululwe kwisisombululo se-isotonic sodium chloride. Kuyadingeka ukufaka umuthi kancane. Ukwelashwa kokungenela kufanele kuhlale okungenani isigamu sehora. Isixazululo sisetshenziswa masisha ngemuva kokulungiswa, kumele sivikelwe elangeni ngangokunokwenzeka.
Ngama-neuropathy ophuzo oludakayo, umuthi uphathwa ngaphakathi kwamasonto ama-2. Kamuva, baphendukela ezidakamizweni kwifomu lethebhulethi ngomphumela ofanayo wokwelapha.
Ngezinjongo ze-prophylactic, i-10 ml yesisombululo esifakwe ku-250 ml we-sodium chloride ibhaliswa izinsuku eziyi-10. Uma kunesidingo, umthamo ungandiswa.
Ngoshukela
Ama-infravenous drip infusions aphathwa ku-250 ml noma ku-300-600 mg kanye ngosuku. Ukwelashwa okunjalo kwenziwa ngenyanga. Ngemuva kokuthi umjovo uqediwe, isiguli sidluliselwa ezinhlotsheni zezidakamizwa zomlomo. Ukuphathwa okunjalo kungasetjenziswa kwabesilisa nabesifazane.
Imiphumela emibi yeTio-Lipona Novofarm
Ukusabela okuvame kakhulu yi-hypoglycemia. Ukungezwani komzimba ngendlela ye-urticaria nakho kungavela kaningi. Ukusetshenziswa isikhathi eside kwesidakamizwa kungadala isicanucanu kanye ukushisa kwenhliziyo. Uma isixazululo siphethwe isikhathi eside, ukuvela, ukuqunjelwa kwezitho zomzimba ngaphansi kwesikhumba kanye nolwelwesi lwama-mucous kungavela. Ukwanda kwengcindezi ye-intracranial kanye nokuphefumula kungabonakala lapho isixazululo sifakwa ngokushesha okukhulu.
Umthelela ekhonweni lokulawula izindlela
Ngoba kukhona ubungozi bokuthuthukisa i-hypoglycemia, iziguli kufanele zaziswe ngalokhu ngaphambi kokushayela. Ukunakekelwa okukhethekile kumele kuthathwe lapho kusetshenzelwa izindlela eziyinkimbinkimbi.
Imiyalo ekhethekile
Iziguli ezinomlando we-mellitus yesifo sikashukela kudingeka ziqaphele njalo amazinga azo kashukela. Ukugwema ukuqala kwezimpawu ze-hypoglycemia, kuyadingeka ukunciphisa umthamo we-insulin osetshenzisiwe. Ama-Ampoules anesixazululo asuswa kusuka ekuhlanganisweni ngokushesha ngaphambi komjovo. Izilwane ezihamba nesixazululo kufanele zivikeleke elangeni.
Sebenzisa ebudaleni
Ukulungiswa komthamo kuyadingeka ngenxa yengozi ye-hypoglycemia. Uma isimo esivamile siba sibi, umthamo wehliselwa ukusebenza okungenani.
Isabelo sezingane
Lesi sidakamizwa asisetshenziswa ekuziphatheni kwezingane.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Ngoba Njengoba into esebenzayo ingena ekuvinjelweni kokuvikela kwe-placenta, ingaba nomthelela we-teratogenic ne-mutagenic kwi-fetus. Ngakho-ke, ukusetshenziswa komuthi ngesikhathi sokukhulelwa kwenqatshelwe.
I-Lipoic acid nayo idlulela obisini lwebele. Ngakho-ke, ngesikhathi sokwelashwa, kungcono ukuyeka ukuncelisa ibele.
Isicelo sokusebenza kokulimala kwezinso
Inhloso yesidakamizwa incike ekuthini imvume ye-creatinine. Lapho ephakeme, yehlisa umthamo wemithi enqunyelwe.
Sebenzisa umsebenzi wesibindi okhubazekile
Ukuthatha umuthi ngokwehluleka kwesibindi okunamandla akukanconywa.
Ukuthatha umuthi ngokwehluleka kwesibindi okunamandla akukanconywa.
Ukweqisa kweTio-Lipona Novofarm
Umuthi ubekezelelwa kahle yiziguli, kanti nezimpawu zokweqisa ngokweqile cishe azenzeki. Uma ngephutha uthatha umthamo omkhulu womuthi, izimpawu zingavela njengokucanuzelelwa kwenhliziyo, ukuhlanza kanye nekhanda elinzima, ukubonakaliswa kwe-hypoxia yobuchopho.
Ukwelapha kuleli cala kuyimpawu. Uma izimpawu zokudakwa zinamandla kakhulu, yenza owengeziwe we-detoxification therapy.
Ukuxhumana nezinye izidakamizwa
Isiza ukwenza buthaka umphumela ngemuva kokuthatha iCisplatin. Kuyelulekwa ukuyithatha ngemuva kwesidlo sakusihlwa noma kusihlwa. Umsebenzi uyancipha esimweni sokuphathwa kanyekanye ngokulungiswa kwe-calcium ne-iron, imikhiqizo yobisi.
U-Ethanol unciphisa kakhulu umphumela wokwelapha wokuthatha umuthi. I-insulin nezinye izidakamizwa ze-hypoglycemic zifaka isandla ekwandiseni umphumela wezokwelapha wokuthatha i-thioctic acid.
Ukuhambisana notshwala
Umyalo wesidakamizwa uphakamisa ukuthi awunakuhlanganiswa notshwala. Lokhu kuholela ekwandeni kwezimpawu zokudakwa futhi kwenziwe buthaka imiphumela ye-thioctic acid.
Ama-Analog
Kukhona ama-analogues atholakala ngohlobo lwe-30 mg amaphilisi, i-film-camera, nezisombululo:
- I-Berlition 300;
- I-Berlition 600;
- I-Lipoic acid;
- I-Thiogma;
- Ipolitiki;
- I-Thioctic acid;
- Tiolepta;
- I-Thioctic acid-Vial;
- Neuroleipone;
- I-Oktolipen;
- I-Lipothioxone;
- Espa Lipon.
Imibandela yekhefu lekhemisi
Ngokusebenzisa umuthi.
Ngingakwazi ukuthenga ngaphandle kadokotela?
Cha.
Intengo yeTio-Lipon Novofarm
Izindleko zivela kuma-ruble angama-400 ngokugxila ngakunye ukuthola isixazululo samabhodlela ayi-10.
Izimo zokugcina zomuthi
Indawo yokubekelwa kukhethiwe mnyama futhi yomile, izinga lokushisa + 25 ° C. Ngoba I-thioctic acid ithinta kakhulu ukukhanya, amabhodlela kufanele agcinwe ebhokisini lekhadibhodi kuze kube yilapho esetshenziswa ngqo.
Isikhathi sokuphelelwa yisikhathi
Hhayi ngaphezulu kweminyaka engu-2.
Umkhiqizi
Inkampani ye-LLC "i-Novopharm-Biosynthesis", i-Novograd-Volynsky, Ukraine.
Ukubuyekezwa mayelana ne-Tio Lipone Novofarm
UMarina, oneminyaka engama-34
I-Tio-Lyon Novofarm infusions yanqunyelwa isifo sikashukela se-polyneuropathy. Thatha umuthi kuphela njengoba uyalelwe udokotela wakho. Inkambo yokwelashwa yayiyizinyanga ezintathu. Ekuqaleni kwenkambo yokwelapha, umuthi wawunqunywe ukuthi ufakwe emithanjeni, bese udluliselwa kumathebulethi afanayo ukuze uwulondoloze. Ukuhlaziywa sekuthuthukile. I-metabolism emzimbeni wami ibuyele kwesejwayelekile. Umuthi muhle kakhulu ngobuncane bemiphumela emibi.
UPavel, oneminyaka engama-28 ubudala
Okuwukuphela kokubi kwalesi sidakamizwa ukuthi akuvamile ukuba usithenge ekhemisi ngokushesha. Udinga kuphela uku-oda kwangaphambili. Inezakhiwo ezinhle ze-antioxidant. Kwaba lula ngemuva kwenkambo yokwelashwa, isimo esejwayelekile saba ngcono kakhulu. Intengo yinhle, akukho nhlobo umphumela omubi. Ekuqaleni kokwelashwa, ikhanda lami lalinesiyezi, kodwa-ke konke kwahamba. Ngeluleka umuthi.
UPavlova M.P.
Ngudokotela wezinzwa. Ngibeka lesi sidakamizwa kaningi, ngoba Inomphumela omuhle we-antioxidant uma kwenzeka kune-polyneuropathy. Ekusebenziseni, ngisebenzisa lo muthi ukwelapha isibindi, kanye nokwelashwa okuyinkimbinkimbi kwe-neuritis kanye ne-radiculopathy. Umuthi unobuncane bemiphumela emibi kanye nentengo engabizi.
