Ungayisebenzisa kanjani i-Cyfran 1000 yesifo sikashukela

Ekwelapheni izifo eziningi ezibangelwa amagciwane, umuthi i-Cifran uvame ukusetshenziswa kwezokwelapha. Ukusebenza kahle kakhulu, ukubonwa okuningana kokusebenza nokubekezelela okuhle kuchaza ukusetshenziswa kwomuthi ku-urology, i-gynecology, i-otolaryngology, ukuhlinzwa, i-ophthalmology nezinye izindawo zemithi.

Igama Lezwe elingafanele

Igama elingabambeki emhlabeni jikelele yi-ciprofloxacin.

Ekwelapheni izifo eziningi ezibangelwa amagciwane, i-Cifran (Ciprofloxacin) ijwayele ukusetshenziswa kwezokwelapha.

I-ATX

Ikhodi ye-ATX J01MA02.

Khipha amafomu nokwakheka

IDigran 1000 iyatholakala ngefomu lethebhulethi, elihlanganiswe ngokuhlanganiswa kwefilimu. Zinesimo esisezingeni eliphakeme futhi zipendwe ngombala omhlophe noma o-milky. Kwifilimu yokunamathela kukhona umbhalo othi "Cifran OD 1000 mg", owenziwe ngoyinki omnyama odliwayo.

Amacwecwe ahlanganiswe emabhulini ezincezu ezi-5. Ukupakisha - ibhokisi lekhadibhodi eliqukethe amaphilisi ayi-5 noma ayi-10.

Isenzo se-Pharmacological

I-Cifran yi-ejenti elumelayo futhi ingeyoqembu le-fluoroquinolones. Isenzo saso sihloselwe ekubhujisweni kwe-bacterial enzyme topoisomerase II, ebandakanyeka ekwakhiweni kwe-bacterial DNA. Ngenxa yalokhu, i-pathogenic microorganism ilahlekelwa amandla ayo okuqhubeka nokuthuthukisa nokukhiqiza kabusha.

Amagciwane amaningi azwela i-ciprofloxacin:

1. Ama -organices wegram-positive aerobic. Phakathi kwazo kukhona i-Enterococci, i-staphylococci, i-streptococci, i-listeria kanye ne-ejenti yokubulala i-anthrax.
2. Amagciwane angama-aerobic we-Gram-negative. Leli qembu lifaka ama-cytrobacter, uShigella, uSalmonella, u-E. coli kanye ne-Haemophilus influenzae, iNeiseria, i-Enterobacteriaceae, amagciwane e-genus Campylobacter, Moraxella, Serratia, Providencia.

Ama -organices we-pathogenic alandelayo anokungazethembi umuthi:

• izinhlobo eziningi zohlobo lwe-Burkholderia cepacia;
• Clostridium Hardile;
• ezinye izingqinamba zeStenotrophomonas maltophilia.

I-Pharmacokinetics

I-Ciprofloxacin ibonakala ngokufakwa ngokushesha okuvela emgodini wesisu. Kulokhu, ukukhishwa kwento esebenzayo kwenzeka ngokulinganayo, ngenxa yokuthi umphumela wokwelapha ugcinwa lapho usebenzisa iTsifran njalo emahoreni angama-24.

Ukuhlungwa kwe-plasma okuphezulu kufinyelelwa emahoreni ayi-6 ngemuva kokuphatha. Le nkomba ilingana no-0.0024 mg / ml. Izifundo zemitholampilo zikuqinisekisile ikhono le-ciprofloxacin ukungena kuwo wonke uketshezi lomzimba. Ukuba khona kwalesi sidakamizwa kutholakele ku-lymph, mate, fluid peritoneal, bronchial secretion fluid, secretion of mucosa nasal, kanye secretion secretion kanye nobudoda.

I-metabolism engxenye yenzeka esibindini. Isigamu sempilo amahora angama-3.5-4,5. Ukuhoxiswa kwenzeka ngezinso (cishe ama-50%). Kulesi simo, i-15% isuswe ngendlela yama-metabolites asebenzayo.

Ukuqedwa kwesigamu sempilo kaTsifran 1000 silingana namahora angama-3.5-4,5; ukuhoxa kwenzeka ngezinso.

Okusizayo

I-Ciprofloxacin iyasebenza ezifweni ezibangelwe ngamagciwane alalela izidakamizwa. Uhlu lokuxilongwa okutholwe kulo i-Digital:

• sinusitis oyingozi;
• ukwanda kwe-bronchitis engapheli;
• inyumoniya
• Izinkinga ze-cystic fibrosis, enesimo esithathelwanayo;
• i-pyelonephritis;
• i-cystitis nezinye izifo ezithinta umchamo;
• i-bacterial prostatitis engapheli;
• i-gonorrhea;
• izifo zesikhumba;
• umfutho we-gallbladder;
• cholangitis;
• amathumba
• i-peritonitis;
• i-anthrax;
• ukutheleleka ngegciwane kwamehlo;
• sepsis
• i-osteomyelitis (i-acute and chronic) nezinye izifo zamathambo namajoyinti;
• umkhuhlane we-typhoid;
• isifo sohudo esithathelwanayo.

Contraindication

Ngaphambi kokusebenzisa umuthi, kubalulekile ukuba uzijwayeze ama-contraindication. Phakathi kwazo kukhona:

• ukungabekezelelani komuntu ngamunye kwe-ciprofloxacin noma ama-antiinakilasi eklasi we-quinolone
• hypersensitivity kuzakhi zeCyfran;
• izingane ezingaphansi kweminyaka engu-18;
• ukuntuleka kwe-glucose-6-phosphate dehydrogenase;
• isikhathi sokukhulelwa nokukhulelwa;
• umlando wokuhlaselwa;
• i-pseudomembranous colitis;
• ukulimala kobuchopho.

Idijithali ihlukaniswe ezinganeni ezingaphansi kweminyaka engu-18.

Idijithali i-contraindicated ngesikhathi sokukhulelwa.

Idijithali ihlukaniswe ku-pseudomembranous colitis.

Idijithali ichazwe ngokonakala kokulimala kobuchopho.

Ngokunakekela

Imiyalo futhi ikhombisa izimo eziningana ze-pathological lapho kulungiswa khona irekhodi lokwelashwa neTsifran. Lokhu:

• ukwehluleka kwezinso nge-creatinine clearance level ye-35-50 ml / min;
• ukusakazeka kwengcindezi yomgogodla;
• i-arrososososis yobuchopho;
• ukugula kwengqondo;
• isithuthwane
• ukwehluleka kwesibindi;
• izilonda ze-tendon ezibangelwa ukusetshenziswa kwama-fluoroquinolones.

Ungayithatha kanjani i-Digital 1000

Izibhebhe kufanele zigwenywe zigcwele futhi zigezwe ngamanzi amaningi. Ukwahlukanisa nokuhlafuna akukhuthazwa. Udokotela ukhetha umthamo osuselwa ekuxilongeni nasosigulini isimo sakhe.

Njengomthamo ojwayelekile wezifo ezingelula, ithebhulethi eyi-1 yeCyfran isebenza kanye ngosuku (njalo ngamahora angama-24).

Ngefomu lesifo esinzima, umthamo wansuku zonke ungangezelelwa ube ngu-1500 mg. Ukwelashwa kwe-gonorrhea elula, umthamo owodwa we-1000 mg wesidakamizwa unele.

Isikhathi sokwelapha siyahlukahluka kusuka kwezinsuku ezintathu kuya kwezingu-14.

Nge-anthrax, kunconywa ukuthatha ithebhulethi eyi-1 yeCyfran ngosuku izinsuku ezingama-60.

Ukuthatha umuthi wesifo sikashukela

Lapho usebenzisa umuthi ukwelapha izifo ezigulini ezinesifo sikashukela, kudingeka ukuthi kuqashelwe ukwelashwa njalo.

Ukwelashwa kwezifo ezigulini ezinesifo sikashukela, kudingeka ukuthi kuqashelwe ukwelashwa njalo.

Imiphumela emibi

Imiphumela emibi ejwayelekile eyenzeka ngesikhathi sokwelashwa nge-ciprofloxacin yilena:

• ubuthakathaka obujwayelekile;
• i-photosensitivity;
• i-pseudomembranous colitis;
• ukujuluka ngokweqile;
• candidiasis.

Kunobufakazi bemiphumela emibi evela ohlelweni lwe-musculoskeletal. Kulokhu, i-tendovaginitis, isifo samathambo, ukuqhuma kwe-tendon, i-arthralgia noma i-myalgia.

Amapheshana wesisu

Kaningi kunabanye, isicanucanu, ubuhlungu besisu, ukuthamba, ukuhlanza. Isifo sohudo, i-anorexia, i-cholestatic jaundice, i-hepatitis, i-hepatonecrosis ayivamile.

Izitho zeHematopoietic

Ukusuka ohlelweni lwe-hematopoietic, lokhu okulandelayo kungenzeka: i-granulocytopenia, i-leukopenia, i-hemolytic anemia, i-thrombocytopenia, i-thrombocytosis, i-leukocytosis ne-eosinophilia.

Isistimu yezinzwa ephakathi

Ezinye iziguli zikhononda ngokuqwasha, isiyezi, ikhanda, ukuqaqamba nokukhathala. Kukhona nobufakazi bemiphumela emibi njengokudideka, ukweqisa kwamaphethelo, ukulahleka kwengqondo, ukubona izinto ezingekho emthethweni, ukuba khona kokuphathelene ne-psychotic kanye nengozi yokuba ne-cerebral artery thrombosis.

Lapho uthatha iTsifran 1000, ezinye iziguli zikhononda ngokuqwasha.

Kusuka ohlelweni lomchamo

Ngesikhathi sokulashwa ngeCifran, i-hematuria, ukubambezeleka komchamo, i-polyuria, i-crystalluria kungenzeka. Okungaphansi kakhulu okuvame ukubonwa yi-albhamuinuria, i-nephritis eyingozi kakhulu ye-interstitial, ukwehluleka kwezinso okulimazekayo, nokopha kwe-urethral.

Kusuka ohlelweni lwezinhliziyo

Ezinye iziguli zinomfutho wegazi ophansi, ukushaya kwenhliziyo okuphazamisekile, ukushiswa ebusweni njalo ne-tachycardia.

Allergies

Uma isiguli sine-hypersensitivity kuma-fluoroquinolones noma izakhi zezidakamizwa, kusabela okungezwani nalokho. Kuhambisana nokulunywa kwesikhumba, okhalweni, umkhuhlane wezidakamizwa, ukwakheka kwamablawu, ukufushane komoya. Ezimweni ezingavamile, imiphumela emibi kakhulu yenzeka. Phakathi kwazo kukhona i-necrolysis enobuthi, i-vasculitis, i-erythema multiforme exudative, ne-Stevens-Johnson syndrome.

Imiyalo ekhethekile

Ukuze unciphise ubungozi be-photosensitivity, iziguli kufanele zigweme imisebe ye-ultraviolet. Kubaluleke kakhulu ukungavumeli ukukhanya kwelanga ngqo esikhunjeni. Lapho kuzwela ukukhanya kukhanya, umuthi uyamiswa.

Enye yezindlela zokuphendula ezingezinhle yi-crystalluria. Ukuyivimbela, udinga ukusebenzisa amanzi anele.

Udokotela kufanele axwayise iziguli ngokubukeka okungenzeka kobuhlungu kuma-tendon. Ngalesi simpawu, iCiphran ikhanseliwe ngenxa yengozi enkulu yokuqhekeka kwe-tendon.

Ukuhambisana notshwala

Ukuhlanganisa ukwelashwa ngama-antibiotic nokuphuza utshwala akuvunyelwe ngokuphelele. Kukhona ingozi enkulu yemiphumela emibi kakhulu.

Ukuhlanganisa ukwelashwa ne-Tsifran 1000 nokuphuza utshwala akuvunyelwe ngokuphelele.

Umthelela ekhonweni lokulawula izindlela

Ngesikhathi sokulashwa, kufanele wenqabe ukushayela futhi uhlanganyele emisebenzini ehlukahlukene engaba yingozi, kubandakanya nezemidlalo ethile.

Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba

Odokotela abaluniki umuthi kwabesifazane ngesikhathi sokukhulelwa. Ngesikhathi sokuqunjelwa, ingxenye encane ye-ciprofloxacin idlula ubisi lwebele. Ngenxa yalesi sizathu, ukunqamuka kufanele kuphazanyiswe.

Inhloso yeTsifran ezinganeni ezi-1000

Ezinganeni, ukwakheka okusebenzayo kwesikhumba. Ukuze ugweme ukuthuthukiswa kwe-pathologies, i-Tsifran icutshwe ezinganeni ezingaphansi kweminyaka engu-18 ubudala.

Sebenzisa ebudaleni

Lapho kunqunywa lesi sidakamizwa, abantu asebekhulile kufanele bacabangele ukusebenza kwezinso okulimazekile. Ngokusekelwe kulesi sici, udokotela kufanele alungise umthamo.

Lapho unquma i-Cyfran kwabadala, umthamo kufanele uguqulwe ngudokotela.

Isicelo sokusebenza kokulimala kwezinso

Ezigulini ezihluleka kakhulu yizinso, kwehla ukuhoxiswa kwe-ejenti elwa namagciwane. Ukuvimbela ukweqisa, ivolumu yomuthi kufanele iguqulwe ngokunaka imvume ye-creatinine.

Ukweqisa

Ukudlula umthamo onconyiwe kungadala imiphumela enobuthi ezinso. Kulokhu, kutholakala izimpawu ezinjengesiyezi, isicanucanu, ukubekezela, ukozela, ukugabha, ukudideka.

Ayikho i-antidote ethile, ngakho odokotela bathatha lezi zinyathelo ezilandelayo:

• ukuhanjiswa kwesisu;
• ukudonswa kwekhabhoni ocushiwe nenani elikhulu loketshezi;
• ukuthatha imishanguzo equkethe i-calcium ne-magnesium;
• hemodialysis.

Uma kwenzeka okweqa ngokweqile kweCyfran, amalahle ocushiwe ngenani elikhulu loketshezi kufanele athathwe.

Ukuxhumana nezinye izidakamizwa

1. Ngama-metronidazole, aminoglycosides, clindamycin. Uma kuthathwa ndawonye, ​​kukhona ingozi yokuthuthukisa ama-synergies.
2. Nge-tizanidine. Mhlawumbe ukwehla okubukhali kwengcindezi yegazi, ukubonakala kwesimba.
3. Nge-theophylline. Umphumela wesidakamizwa uyanda, ngakho-ke, ukulungiswa komthamo kuyadingeka.
4. Ngemithi evimba ukugcinwa kwe-tubular secretion (kufaka phakathi i-probenecid). I-antimicrobial reso excretion iyancishiswa.
5. Ngama-antacid, aqukethe i-magnesium noma i-aluminium hydroxide. Le nhlanganisela ayinconywa, ngoba ukufakwa kweCyfran kuncishisiwe.
6. Ngama-analgesics. Lapho isetshenziswa ndawonye, ​​imiphumela emibi evela ohlelweni lwezinzwa oluyinhloko ivame ukuvela.
7. Nge-cyclosporine. Umphumela we-Nephrotoxic uyanda. Kulezi zimo, ukuqapha i-serum creatinine kabili ngesonto kuyadingeka.
8. Ngamalungiselelo e-uricosuric. Kunokwehla kokukhishwa kwe-antibiotic ngo-50%.
9. Ngama-warfarin namanye ama-anticoagulants omlomo. Umphumela wale mishanguzo uyathuthukiswa, mhlawumbe othinta ukuminyana kwegazi.
10. Nge-glyburide. Ukuhlanganiswa kungaholela ekukhuleni kwe-hypoglycemia.

Ama-Analog

Izibhebhe ze-Tsifran zinama-analogu amaningi. Phakathi kwazo kufanele kubizwe:

• I-Tsifran OD;
• I-Tsifran ST;
• I-Ciprofloxacin;
• I-Basidzhen;
• I-Vero-Ciprofloxacin;
• I-Procipro
• I-Quintor;
• Ififpro;
• UNarzip
• I-Ciprinol.

Akunconywa ukuthi ungene esikhundleni somuthi nge-analogue ngokwakho. Ukuze wenze lokhu, thintana nodokotela wakho, njengoba kungadingeka ukulungiswa komthamo.

Izimo zeholide le-Tsifran 1000 kusuka kumakhemisi

Umuthi usatshalaliswa ngugqirha.

Ngingakwazi ukuthenga ngaphandle kadokotela

Imithi ethengiswa ngaphezulu kuleli qembu ayithengiswa.

Intengo

Izindleko zeCifran ngomthamo we-1000 mg ziyehluka kusuka kuma-ruble angama-350 kuya kwangama-390 kwithebhulethi eyi-10.

Izimo zokugcina zomuthi

Udinga ukugcina umuthi endaweni yokushisa ka- + 15 ... + 25 ° C endaweni evikelwe umswakama nokukhanya kwelanga okuqondile.

Isikhathi sokuphelelwa yisikhathi

Isikhathi sokugcina - iminyaka emi-2 kusukela ngosuku lokukhishwa.

Umkhiqizi Tsifran 1000

Umuthi ukhiqizwa yinkampani iSan Pharmaceutical Industrial Ltd. (India).

I-Digital Pharmaceuticals San Industries Co Ltd. ikhiqiza iDijithali. (India).

Ukubuyekezwa kwe-Tsifran 1000

Odokotela baphawula ukusebenza okuphezulu kweCyfran nokubekezelelana okuhle. Lokhu kungahlulelwa kusuka kuzibuyekezo eziningi.

Odokotela

U-Eugene, udokotela wezifo zabesifazane, isipiliyoni kwezindlela zokwelapha - iminyaka engama-21

Ngezifo ze-gynecological zemvelaphi yamagciwane, iTsifran ingesinye sezidakamizwa esisebenza ngempumelelo. Umthamo we-1000 mg unomphumela ohlala njalo, ngakho-ke ukuyithatha kanye ngosuku kwanele.

UKonstantin, udokotela ohlinzayo, isipiliyoni kwezokwelapha - iminyaka engama-27

Inkambo yokwelashwa yesikhashana inqunyelwe esikhathini se-postoperative ukuvimbela izinkinga. Umuthi uyasebenza. Emsebenzini, kube nezimo eziningana nemiphumela emibi. Iziguli zithole ukusabela komzimba ngendlela yokuqhuma.

Iziguli

UPolina, oneminyaka engama-45 ubudala, uNovokuznetsk

Ngiye emtholampilo nge-ARVI egijimayo. Isikhathi esithile wazama ukwelashwa ekhaya ngethemba lokuthi uzozizwa engcono. Ekupheleni kosuku lwesibili lokwelashwa neTsifran kwaba lula kakhulu. Izinga lokushisa lehla, ukukhwehlela kancipha.

UValery, oneminyaka engama-38, uVladivostok

Udokotela unikeze la maphilisi ukuthi afake amanye awasizanga (angikhumbuli igama). Ukuxilongwa i-bacterial prostatitis. Isibalo sisizile. Welashwa isikhathi eside, cishe amasonto amathathu.