I-Reduxin ilawula isifiso sokudla futhi sinomphumela wobuthi, yingakho isetshenziswa ekwelashweni okuyinkimbinkimbi kokukhuluphala. Amathebhulethi e-Reduxine ayindlela engatholakali; umuthi uyatholakala ngesimo samaphilisi we-gelatin.
Ifomu nokukhululwa okukhona
Into esebenzayo enjengempuphu ifakwe kumakhompiyutha aqinile. Zitholakala ngemibala emi-2 - luhlaza okwesibhakabhaka. Lokhu kwenziwa ngokukhethekile ukuhlukanisa phakathi kwemithamo ye-10 ne-15 mg.
I-Reduxin ilawula isifiso sokudla futhi sinomphumela wobuthi, yingakho isetshenziswa ekwelashweni okuyinkimbinkimbi kokukhuluphala.
Umuthi uhlanganisiwe, uqukethe izinto ezi-2 eziphambili - i-sibutramine ne-cellulose. Izakhi ezisizayo ziyi-calcium stearate kanye ne-capsule ye-gelatin.
Igama Lezwe elingafanele
ISibutramine + [Microcrystalline Cellulose].
Amaresiphi ngesiLatin aqukethe igama esimweni sofuzo uSibutramini + [Cellulosi microcrystallici].
I-ATX
Izidakamizwa ze-A08A zokwelapha ukukhuluphala (ngaphandle kwemikhiqizo yokudla).
Isenzo se-Pharmacological
Inhlanganisela yezidakamizwa inemiphumela emi-2 eyinhloko - ukulahlekelwa kwesifiso sokudla kanye nokukhipha izidakamizwa.
I-Sibutramine, uma idliwe, isetshenziswa kumamayini, evimbela ukuqalwa kabusha kwe-dopamine, i-serotonin ne-norepinephrine. Ngenxa yalokhu, isiguli sibona ukwehla kwesifiso sokudla futhi sizizwe sigcwele inani elincane lokudla. Futhi, umzimba ukhulisa ukukhiqizwa kokushisa ngenxa yomphumela ongaqondile we-brown adipose izicubu.
Ngesikhathi sokulashwa, isiguli sihlela ukuthi umzimba we-lipid metabolism, ubhekwe udokotela ukuze ahlaziye. Ku-plasma yegazi, inani le-cholesterol ye-HDL ("enhle") liyenyuka futhi izinga le-cholesterol ephelele, kufaka phakathi "okubi" (LDL), lehla.
Inhlanganisela yezidakamizwa inemiphumela emi-2 eyinhloko - ukulahlekelwa kwesifiso sokudla kanye nokukhipha izidakamizwa.
I-cellulose isebenza njenge-enterosorbent, ekuvumela ukuthi ususe ubuthi bangaphandle nobungaphandle bomzimba.
I-Pharmacokinetics
Lapho uthathwa ngomlomo, ugxilwa ngokushesha ungene egazini, bioavailability - 77%. Ukwakheka kwama-metabolites asebenzayo kwenzeka esibindini. Ukuthatha amaphilisi wokudla ngokudla kuholela ekunciphiseni kwenani eliphezulu lama-metabolites cishe ingxenye yesithathu.
Isikhathi sokuphila se-sibutramine yihora eli-1 imizuzu eyi-10, ama-metabolites aso - aze afike emahoreni ayi-16. Njengomphumela we-conjugation kanye ne-hydroxylation, ama-metabolites angasebenzi ayakhiwa, adalulwa ikakhulukazi kumchamo.
Kubekelwe ini?
Umuthi ukhonjiswa njengengxenye yokwelashwa okuyinkimbinkimbi kokulahlekelwa kwesisindo kwiziguli ezinokukhuluphala kwe-degree yokuqala nangaphezulu (inkomba yesisindo somzimba ngaphezulu kwama-30 kg / m²). I-Reduxin inqunyelwe izizathu zokudla okunempilo ukuze uzuze isisindo, isb. ukukhuluphala okuhambisana nokudla ukudla ngokweqile.
Uma isiguli sinokukhuluphala okuhlanganiswe nohlobo 2 sikashukela ne-hyperlipidemia, khona-ke amaphilisi angabekelwa i-BMI efinyelela kuma-27 kg / m².
I-Reduxin inqunyelwe izizathu zokudla okunempilo ukuze uzuze isisindo, isb. ukukhuluphala okuhambisana nokudla ukudla ngokweqile.
Ngaphambi kokuchaza umuthi, udokotela kufanele aqiniseke ukuthi ukudla nokudla okwenziwe ngomzimba akuzange kube nomphumela obonakalayo, futhi isiguli asikwazi ukulawula inkanuko yaso ngokwaso.
Contraindication
Ekukhathaleni okubangelwa yizifo ze-endocrine ne-bulimia amanosa, umuthi ubekiwe. Ungasebenzisi iReduxine nge:
- hypersensitivity kuzakhi zomuthi;
- ukugula kwengqondo;
- Isifo sikaTourette's;
- izifo zenhliziyo nemithambo yegazi, kufaka phakathi kuma-anamnesis;
- i-cerebrovascular pathologies;
- i-thyrotooticosis;
- ukwephulwa okukhulu kwesibindi nezinso;
- isimila se-Prostate;
- pheochromocytoma;
- umlutha wezidakamizwa noma wotshwala.
Kwabesifazane ngesikhathi sokukhulelwa nangesikhathi sokukhulelwa, lesi sidakamizwa asinqunyelwe. ISibutramine icutshaniswe nezingane nasezigulini esezikhulile (ngaphezulu kweminyaka engama-65).
Ngezifo ezihlangana zidinga ukusetshenziswa kwama-monoamine oxidase inhibitors, ama-antidepressant, amaphilisi okulala nama-antipsychotic, i-Reduxine angeke isetshenziswe.
Ungayithatha kanjani i-Reduxine?
Amakhompiyutha athathwa ngomlomo (wonke amanzi amaningi) kanye ngosuku ekuseni, angaba esiswini esingenalutho noma ngesikhathi sokudla kwasekuseni.
Udokotela unquma umthamo, kunconywa ukuqala nge-10 mg ngosuku, uma umuthi ungabekezelelwa kahle, kuvunyelwe ukuwuhlisela ku-5 mg. Uma kwenzeka kunemiphumela engagculisi yokwelashwa, lapho ngemuva kwenyanga isiguli sesilahlekelwe ngaphansi kwesisindo esingama-2 kg, udokotela angabeka amaphilisi angama-15 mg. Uma kungamaviki ayi-12 ukulahleka kwesisindo kungafikanga i-5% yesisindo somzimba sokuqala, umuthi ukhanseliwe.
Isikhathi sonke sokwelashwa akufanele sibe ngaphezu kwezinyanga eziyi-12, ngoba akukho datha yokuphepha ethatha isikhathi eside.
Ukwelashwa kwe-Reduxine kufanele kuhambisane nokudla kanye nokuzivocavoca okwanele komzimba.
Mangaki amaphilisi engingawaphuza ngosuku?
Kuyadingeka ukuthi ungathathi ngaphezu kwe-1 capsule ngosuku. Uma weqa ukungena ngakusasa ngqa, awudingi ukuphinda umthamo ophindwe kabili.
Ngoshukela
Ukusetshenziswa kweziguli ezinesifo sikashukela kufanelekile, ngoba ivumela ukwenza ngokwejwayelekile i-lipid metabolism, inciphise ingozi yokufa kusuka ekuphazamisweni kwenhliziyo futhi ikhuphule izinga lokuphila lesiguli. Umthamo wansuku zonke yi-10-15 mg, irekhodi lilawulwa ngudokotela.
I-Reduxine akumele ithathwe ngaphezulu kwe-1 capsule ngosuku. Uma weqa ukungena ngakusasa ngqa, awudingi ukuphinda umthamo ophindwe kabili.
Imiphumela emibi yeReduxine
Imvamisa, imiphumela emibi iphawulwa ngenyanga yokuqala yokwelashwa; ngokuhamba kwesikhathi, inganciphisa noma inyamalale.
Engxenyeni yesitho sombono
Ukucaciswa okubonakalayo okwehlisiwe, umuzwa weveli phambi kwamehlo.
Amapheshana wesisu
Ukwehla ngokweqile kokudla kokudla kuze kufike ekulahlekelweni kwesifiso sokudla. Ukuqunjelwa okungenzeka kanye nokwanda kwama-hemorrhoids. Ucwaningo lwentengiso lwangemuva lwembula imiphumela emibi ngendlela yokuba nesicanucanu, ukugabha, nohudo. Amacala ahlukaniswe nodwa woshintsho olwanele ekuziphatheni kokudla alotshwa lapho isifiso sokudla sesiguli sanda futhi nomuzwa ongapheli wokoma uvela.
Izitho zeHematopoietic
Esikhathini sokumaketha ngemuva, kwavela amacala okwehla kwenani lamapuleti egazini, okuholele ekutheni kwandiswe isikhathi sokuqina.
Imvamisa, imiphumela emibi iphawulwa ngenyanga yokuqala yokwelashwa; ngokuhamba kwesikhathi, inganciphisa noma inyamalale.
Isistimu yezinzwa ephakathi
Iziguli zivame ukukhononda ngomlomo owomile kanye noshintsho ekunambithekeni. Okwakungasabhekwa kangako ukuqwasha, ikhanda, nokukhathazeka. Ukuphazamiseka kwengqondo kungenzeka: ukudangala, i-psychosis, i-mania, ukuthambekela kokuzibulala. Kulezi zimo, umuthi ukhanseliwe.
Okunye ukusabela okungekuhle kwarekhodwa: ukulahleka kwenkumbulo, ukozela, ukungabekezeleleki, ukungazinzi ngokomzwelo.
Engxenyeni yesikhumba
Ukuthatha amaphilisi wesikhova kungadala ukukhuphuka izithukuthuku, ukulunywa, ukuphuma kwesikhunta ku-dermis kanye ne-alopecia.
Kusuka ohlelweni lwezitho zofuzo
Abesifazane bangaba ne-dysmenorrhea kanye nokuphuma kwe-uterine, amadoda - izinkinga nge-ejaculation kanye ne-potency.
Kusuka ohlelweni lwezinhliziyo
Ukwanda kwesilinganiso senhliziyo kanye nengcindezi ekhuphukayo, i-palpitations, i-fibrillation ye-atrial.
Kusuka ezinso nasegunjini lokuchama
Ukuchithwa kwe-urinary kanye nephritis eyingozi ye-tubulointerstitial.
Ngasohlangothini lwe-metabolism
I-Edema, ukukhuphuka kwe-hepatic transaminases.
Ukuthatha ama-Reduxine Capsule kungadala ukukhuphuka kokujuluka.
Imiyalo ekhethekile
Ezinyangeni zokuqala zokwelashwa, kanye njalo emavikini ama-2, umfutho wegazi kanye nokushaya kwenhliziyo kufanele kubhekwe. Ukunakwa ikakhulukazi kwalezi zinkomba ezigulini ezinomfutho wegazi ophakeme ne-apnea.
Naphezu kweqiniso lokuthi akukho datha emtholampilo ngokulutha kweReduxin, udokotela kufanele anake noma yiziphi izimpawu zokuncika ekhemisi.
Umuthi ungadala ukozela, unciphise ukugxila futhi uthinte ijubane lokuphendula kwe-psychomotor, ngakho-ke, lapho ulawula imishini, udinga ukuqaphela kakhulu.
Uma kwenzeka ukungasebenzi kahle kwezinso
ISibutramine ikhishwa yizinso futhi ingadala ukugcinwa komchamo, ngakho-ke ngokwehluleka kwezinso, umuthi ubekiwe ngokuqapha.
Ngokungasebenzi kahle kwesibindi
I-Biotransformation yento esebenzayo ibe ngama-metabolites iyenzeka esibindini, ngakho-ke, uma imisebenzi yayo iphazamiseka, udokotela angalungisa umthamo noma akhansele umuthi.
Ezinyangeni zokuqala zokwelashwa kweReduxine, umfutho wegazi kufanele ubhekelwe ezigulini njalo emavikini ama-2.
Ukweqisa kweReduxin
Ukweqisa umthamo ovumelekile kungadala ukwanda kokunye okungahambi kahle. Imvamisa, izimpawu zezinhlelo zenzwa nezenhliziyo ziyaphawulwa: ikhanda kanye nesiyezi, tachycardia, umfutho wegazi ophakeme.
ISibutramine ayinayo i-antidote ethile, udokotela kufanele aziswe nge-overdose engaba khona. Ama-sorbents athathwe ngesikhathi noma i-gastric lavage kuzonciphisa ukufakwa kwento egazini. Ngezinguquko ezimenyezelwe ekucindezelweni noma ekuweni kwenhliziyo, udokotela unquma ukwelashwa ngezimpawu zomuthi.
Ukuxhumana nezinye izidakamizwa
Ukuphathwa kanyekanye kweReduxine ngezinye izindlela zokulungisa isisindo, okuthinta isistimu yezinzwa ephakathi, kuyaphikiswa.
I-Rifampicin, i-macrolides, iPhenobarbital ingakhuphula izinga le-metabolic ye-sibutramine.
Ukusetshenziswa kweReduxine ngokuhlangana nezidakamizwa ekwelapheni ukuphazamiseka kwengqondo kuyaphulwa. Ezimweni ezingavamile, ukuhlanganiswa nemithi yokudangala, i-migraine nokukhwehlela kungadala i-serotonin syndrome.
Umuthi awuthinti umphumela wezindlela zokuvimbela inzalo ze-hormonal.
Izifundo eziphathelene nokuhambisana notshwala zibonisa ukuthi iReduxin ayithuthukisi imiphumela yayo emibi emzimbeni. Kepha ukudla okudliwayo ngesikhathi sokwelashwa akufaki ukusetshenziswa kotshwala.
Ukudla okunqunyelwe ekwelashweni kweReduxin akufaki ukusetshenziswa kotshwala.
Ama-Analog
Ezinye izidakamizwa zisetshenziswa ekwelapheni ukukhuluphala:
- IGoldline.
- I-Goldline plus.
- Lindax.
- I-Zimulti.
- I-Dietetress.
- Slimia.
- I-Reduxin Met.
- I-Orsotin Slim.
I-Reduxin Light, esatshalaliswa ngaphandle kadokotela, iyisengezo sokudla, yize kufana amagama, izinto ezisebenzayo zikuhlukile.
Imibandela yekhefu lekhemisi
Umuthi kadokotela.
Ngingakwazi ukuthenga ngaphandle kadokotela?
Ukuthengisa izidakamizwa okubhaliwe ngaphandle kwemithi kadokotela kuphambene nomthetho.
Kubiza malini?
Ngokuya kumthamo nenani lamaphilisi, intengo yesidakamizwa emakhemisi ingahluka kusuka kuma-ruble ayi-1050 kuya kuma-6300.
Izimo zokugcina zomuthi
Endaweni emnyama, epholile.
Isikhathi sokuphelelwa yisikhathi
Iminyaka engu-3 ukusuka ngosuku oluboniswe ku-blister.
Umkhiqizi
E-Russia, lo muthi ukhiqizwa abakhiqizi abangu-2: i-Ozon LLC kanye ne-FSUE Moscow Endocrine Plant.
Ukubuyekezwa
Odokotela
USvetlana, umondli wezempilo, uPm.
I-Reduxin ifakazele isebenza kahle ekusebenzeni. Kepha ngikubeka kuphela uma isiguli singakwazi ukunciphisa umzimba ngokwaso, silandela uhlelo lokudla okunempilo nokudlala imidlalo.
UNatalia, udokotela wenhliziyo, u-Ufa.
Anginiki umuthi, kepha ngihlala ngihlangana neziguli ezisebenzayo futhi ezithola izinkinga ngohlelo lwenhliziyo ngenxa yalokho.
Iziguli
U-Olga, oneminyaka engama-35, eSt.
Ngemuva kwemizamo engaphumeleli yokunciphisa isisindo eyedwa, waguqukela kudokotela obekhiphe uReduxin. Ngenxa yalokhu, ngilahlekelwe ngama-9 kg ngekhosi ngalinye.
UZarina, oneminyaka engama-50, eTatarstan
Ubengaphansi kokuqashwa kwe-endocrinologist kanye ne-wezempilo. Phakathi kwezinye izidakamizwa, uReduxine wabekwa. Kwavela ukuthi kwehle isisindo kungakapheli izinyanga eziyisithupha ngamakhilogremu ayi-12, akubanga namiphumela emibi.
Ukulahlekelwa isisindo
U-Elena, oneminyaka engama-41 ubudala, eYekaterinburg.
Ezinyangeni ezintathu alahlekelwe ama-5 kg, kepha ama-3 kg awo abuyela emuva. Umuthi ungcono kulabo abadinga ukuqeda ama-20-30 kg.
UMaxim, oneminyaka engama-29 ubudala, uKaliningrad.
Umuthi awuzange umlingane nonkosikazi wakhe, yize iphango lakhe lehla, nesisindo saqala ukushiya. Kepha wacasuka kakhulu wakhala.
