Ukuqhathanisa kweTrental ne-Actovegin

Ukwephulwa kokujikeleza kwegazi emithanjeni yobuchopho, izitho zangaphakathi nezingalo kuholela ekuphazamisweni kwemizwa okuhlukahlukene, okuphathelene nenhliziyo, izifo zamehlo kanye nethrophic. Ukwelashwa kwalezi zi-pathologies, kusetshenziswa ama-ejenti athuthukisa ama-microcirculation, izidakamizwa ze-vasodilator, ama-anticoagulants, okusetshenziswa kwegazi neminye imithi.

Izidakamizwa ezidume kakhulu ezisetshenziselwa ukuphazamiseka kwemizwa ne-vascular zihlanganisa i-Trental ne-Actovegin, kanye nama-analogues ale mishanguzo.

Isici seTrental

Into esebenzayo yesidakamizwa Trental yi-pentoxifylline. Yehlisa ukuqina kwe-calcium ngaphakathi kwamangqamuzana, iqinise i-cyclic adesin monophosphate (AMP) futhi inyuse inani lamangqamuzana wamandla (i-ATP) kumaseli abomvu egazi. Umphumela we-antihypoxic (ukuhanjiswa komoya-mpilo oya kumaseli enhliziyo) kungenxa yokwanda kwemithambo yegazi. Ukwanda kwe-lumen yemithambo ye-pulmonary kanye nokwenyuka kwethoni yezicubu zokuphefumula kukhuthaza i-oxygenation yegazi.

Into esebenzayo yesidakamizwa Trental yi-pentoxifylline.

IPentoxifylline nayo inemiphumela elandelayo:

• kuthuthukisa ukuhamba kwegazi, kunciphisa ukuvela kwegazi nokuhlangana kweplatelet;
• kunciphisa ubungozi bokushintshwa kweseli elibomvu;
• kwenyusa umzuzu nomthamo wegazi elimpushwe, ngaphandle kokuthinta isilinganiso senhliziyo;
• umphumela onenzuzo emsebenzini we-bioelectric wohlelo lwezinzwa;
• kususa imvuthuluka nobuhlungu nge-peripheral vascular stenosis.

Izinkomba zokusetshenziswa kweTrental yilezi:

• ischemic stroke;
• ukuvimbela ukuphazamiseka kwe-microcirculation ebuchosheni be-ischemia kanye neuroinfections yegciwane;
• i-encephalopathy;
• ukuphazamiseka kokuhamba kwegazi kwisifo senhliziyo ne-myocardial infarction;
• isifo sokuqina kwemizwa;
• i-neuropathy ye-opic nerve, ukuphazamiseka kwe-retinal trophism kanye ne-microcirculation emikhunjini encane yamehlo ngokumelene nesifo sikashukela i-mellitus;
• izinqubo eziwohlokayo nesifo sokuqina kwendlebe ephakathi nendawo ngemuva kokuphazamiseka kwemithambo endlebeni engaphakathi;
• ukuphazamiseka kokujikeleza emikhunjini yamaphethelo aphansi (kufaka phakathi ukukhalinyana okwenzeka ngezikhathi ezithile);
• ukucindezelwa kwezinzwa zepherishi ngemuva kokulimala komgogodla kanye ne-hernia yama-disc e-intervertebral discs;
• izifo ezingama-pulmonary ezingama-chronic, i-asthma;
• ukuphazamiseka kwe-potency ye-vascular etiology.

I-Trental isetshenziselwa ukwelapha i-ischemic stroke.

Umuthi usetshenziselwa i-atherosclerosis yobuchopho.

Umuthi uthuthukisa ukugeleza kwegazi ngokunciphisa ukubukeka kwegazi nokuhlangana kweplatelet.

Umuthi uyatholakala ngezindlela zokuphatha ngomlomo nangabazali. Umthamo we-pentoxifylline kumathebhulethi yi-100 mg, kanti nesixazululo sokufakwa - 20 mg / ml (100 mg ku-1 ampoule). I-Trental ithathwa ngomlomo, i-intramuscularly, i-intravenly and intraarterically (idonsa, kaningi - ngejethi).

Ukuxhumana kokusebenzisa umuthi yilezi:

• hypersensitivity to an organised analogue of pentoxifylline nezinye izinto zokwakheka;
• ukuphazamiseka kokujikeleza kwezifo obukhulu besicubu senhliziyo nesistimu yezinzwa ephakathi (infyoction myocardial, stroke hemorrhagic);
• isifo se-porphyrin;
• ukulahleka kwegazi okukhulu;
• ukukhulelwa
• ukuncelisa;
• i-retinal hemorrhage;
• ukuphathwa kwabazali kuphela: izinzwa zenhliziyo, izilonda ezinzima ze-atherosulinotic ze-corbrary and coronary artery, hypotension ephikelelayo.

Ngokuthambekela kwe-hypotension, izilonda zesisu kanye ne-duodenal ulcer, ukuhluleka kwesitho esingamahlalakhona, ngesikhathi sokuvuselelwa ngemuva kokuhlinzwa neziguli ezingaphansi kweminyaka engu-18 ubudala, iTrental inqunywa ngokuqapha.

Imiphumela emibi engaba khona yokwelashwa ngezidakamizwa ifaka:

• isiyezi, ikhanda, ukugoba;
• ukungaboni kahle
• ukukhathazeka, ukudangala;
• ukudumba;
• ukuqina kwezipikili;
• ukufiphala kobuso nesifuba;
• ukwehla kwesifiso sokudla;
• ukungasebenzi komthambo, isibindi namathumbu;
• ukukhuphuka kwenhliziyo, i-arrhythmia, i-angina pectoris, kwehle umfutho wegazi;
• ukopha ngaphakathi nangaphandle;
• ukungahambi kahle komzimba;
• ukukhuphuka komphumela we-anticoagulant wama-NSAIDs kanye ne-hypoglycemic isenzo se-insulin.

Imiphumela emibi engaba khona yokwelashwa kweTrental ifaka phakathi ukungaboni kahle.

Izici Actovegin

Umphumela we-pharmacological we-Actovegin ususelwa kwimiphumela ye-antihypoxic ne-metabolic yesakhi sayo esisebenzayo - okukhishwa (okuphuma) egazini lamathole.

I-hemoderivative ikhiqizwa yi-dialysis nokuhlunga kwezinhlayiya ezinesisindo samangqamuzana angama-dalton angaphezu kwezi-5.

Umuthi unemiphumela elandelayo emzimbeni:

• kushukumisa ukuhanjiswa komoya-mpilo kumaseli wesistimu yezinzwa, inhliziyo nezicubu zomzimba;
• kukhuthaza ukuthuthwa nokusetshenziswa ngokuphelele kwama-carbohydrate, kunciphisa ukugcwala kwemikhiqizo ye-oxidation engaphelele ye-glucose (lactates);
• iqinisa ulwelwesi lwe-cytoplasmic ezimweni ze-hypoxia;
• kwandisa ukugcwala kwama-macroergs kanye nokuphuma kwe-glutamic, aspartic ne-gamma-aminobutyric acid.

I-Actovegin imiselwe i-pathologies elandelayo:

• ukwephulwa kohlelo lokujikeleza kohlelo lwezinzwa oluyinhloko ngemuva kokulimala kobuchopho noma ukufakelwa kwamakhemikhali;
• i-thrombosis yemithambo ye-peripheral and coronary, imiphumela yokuvezwa kwamathambo nemithambo (kufaka phakathi izilonda ze-trophic);
• ukwephula ukuhanjiswa kwegazi emithanjeni yezinzwa ezifweni zomgogodla;
• ukwelashwa isikhathi eside kwamanxeba, izilonda, izilonda zokucindezela, ukusha kanye nokunye ukulimala kwezifo ze-vascular, metabolic and endocrine;
• ukulimala kwemisebe yezitho zangaphakathi, ulwelwesi lwama-mucous nesikhumba.

I-Actovegin ivuselela ukuthuthwa komoya-mpilo kumaseli wesistimu yezinzwa, inhliziyo nezicubu eziziwayo.

Umuthi usetshenziselwa i-thrombosis yemithambo ye-peripheral and coronary.

Futhi, umuthi usetshenziselwa ukwephula ukuhanjiswa kwegazi emithanjeni yezinzwa ezifweni zomgogodla.

Kwezinye izimo, ama-infusions we-hemoderivative asetshenziselwa ama-pathologies okukhulelwa (ukuphazamiseka kwegazi okuya ocansini naku-placenta).

I-Actovegin iyatholakala ngezindlela eziningi ze-pharmacological:

• ukugcoba (50 mg / g);
• ijeli (200 mg / g);
• isixazululo sokufakwa (4 mg noma i-8 mg ku-1 ml);
• isixazululo somjovo (4 mg, 8 mg, 20 mg noma 40 mg ku-1 ml);
• amaphilisi (200 mg).

Umuthi ubonakala ngokuhambisana okuhle nezinye izidakamizwa ze-antihypoxic nama-metabolites, kepha akunqwenelekile ukuwuxuba ku-dropper eyodwa.

Ukuxhumana kokusebenzisa umuthi yilezi:

• hypersensitivity kokuphuma kwegazi;
• ukuhluleka kwenhliziyo okungafakwanga;
• i-pulmonary edema;
• ukuphazamiseka kwe-fluid excretion.

I-Actovegin kufanele isetshenziswe ngokuqapha kushukela.

Ngokuqapha, umuthi kufanele usetshenziselwe isifo sikashukela (ngenxa yokuqukethwe kwe-dextrose kuzixazululo ze-derivative), ukugcwala ngokweqile kwe-chlorine nesodium.

Ukwelashwa kungahle kuhambisane nemiphumela yokungezwani komzimba (ukuqunjelwa isikhumba, umkhuhlane, ubomvu kwesikhumba, njll.) Kanye nokugcinwa kwamanzi emzimbeni.

Ukuqhathanisa kweTrental ne-Actovegin

Ama-Actovegin neTrental asetshenziselwa izinkomba ezifanayo. Umphumela ofanayo we-antihypoxic unikezwa izinqubo ezahlukahlukene ze-pharmacodynamic.

Ukufana

Ukufana kwalezi zidakamizwa zombili kuyabonakala kulezi zici ezilandelayo:

• ukusetshenziswa kwezinkinga zokujikeleza kwegazi nezimpawu eziwohlozayo zegazi eziwohlokayo;
• umphumela onenzuzo ezinqubweni ze-metabolic kumaseli, ukuthuthwa komoya-mpilo kanye nokuqongelela i-ATP;
• ingozi enkulu ye-edema ngesikhathi sokwelashwa;
• ukuba khona kwamafomu wokukhishwa komlomo nangabazali.

I-Actovegin neTrental zinomphumela omuhle ezenzweni ze-metabolic kumaseli.

Uyini umehluko?

Umehluko phakathi kwe-Actovegin neTrental uyaphawulwa ezicini ezifana:

• umsuka wento esebenzayo;
• ukusebenza kwezidakamizwa;
• inani le-contraindication nemiphumela emibi;
• ukuphepha kweziguli ezikhulelwe nezikhonkotha.

Yikuphi okushibhile?

Izindleko ze-Actovegin zisuka kuma-ruble angama-361. zama-ampoules amahlanu wesisombululo, kusuka kuma-ruble ayi-1374. amaphilisi angu-50 kanye nama-ruble ayi-190. ngama-20 g wamafutha. Intengo yeTrental iqala kusuka kuma-ruble ayi-146. ama-ampoules ama-5 nama-ruble angama-450. amaphilisi angama-60.

Yini engcono: Trental noma Actovegin?

Inzuzo yeTrental ukusebenza kwayo okufakazelwe. I-pharmacodynamics ne-pharmacokinetics yalesi sidakamizwa icwaningisisiwe kahle, okuvumela ukuthi ukhethe umthamo ngokunemba ngangokunokwenzeka ngokuya ngokuxilongwa kanye ne-pathologies ehlobene nayo.

Ukwelashwa nge-Actovegin akufakiwe kumaphrothokhthi wokwelashwa kwamanye amazwe athuthukile, kepha ama-neurologists amaningi aqaphela umphumela onenzuzo wesidakamizwa kwi-microcirculation kanye nokwehliswa kwezilonda zezicubu ze-hypoxic. Izisombululo namacwecwe weHemoderivative ziphephile futhi zingasetshenziswa ekukhulelweni, ekuqunjweni, izifo zohlelo lwe-hematopoietic, ukuphazamiseka kokujikeleza kwezifo okunempilo, njll.

Uma kukhona ukungqubuzana kokuthatha i-Trental, iMexidol, i-Mildronate nezinye izidakamizwa ezikhuthaza ukugeleza kwegazi emithanjeni yobuchopho, inhliziyo nezinsimbi zokuphefumula kungabekwa kanyekanye nge-Actovegin.

Ukubuyekezwa kweziguli

U-Elena, oneminyaka engama-49, eMoscow

Kusukela ehleli isikhathi eside phambi kwesikrini sekhompyutha kwavela isiyezi, izinhlungu ekhanda nasentanyeni. Udokotela oyi-neurologist wahlonza i-osteochondrosis yomlomo wesibeletho futhi wachaza nemithi eminingana, phakathi kwayo kwakunguTrental. Ngemuva kwenkambo yokuqala, izimpawu zavele zanyamalala, kepha ukwanda kwenzeka ngezikhathi ezithile. Iminyaka emi-3 eyedlule, ngokuvela kwezimpawu zokuqala zokuxhamazela (ama-migraines, ingcindezi yokuqothuka), bengilokhu ngithatha inkambo yokudonsa ama-10 nge-Trental, bese ngiphuza amaphilisi izinyanga ezi-1-2. Ngemuva kwale nkambo, izimpawu ziyanyamalala izinyanga eziyi-6-9.

Ukuntuleka kwemithi - ngesingeniso esisheshayo (ngisho ne-Drip), ingcindezi yehla kakhulu futhi iqala ukuzizwa iyizinyanga.

USvetlana, oneminyaka engama-34, uKerch

Ngemuva kokulimala kobuchopho obuhlukumezanayo, udokotela wanquma i-Actovegin. Ngithatha imijovo njalo ezinyangeni ezingama-6 (izikhathi ezi-2 ngonyaka noma njengoba zidingeka). Sekuvele ngosuku 2 - 3 lwesithathu lokwelashwa, izinhlungu zesisi nesiyezi kuyahamba, amandla okusebenza enyuka, nokukhathala okungamahlalakhona kuyanyamalala. Ukungezwa okungeziwe - phakathi nemijovo, ukuphulukiswa kwamanxeba okusha kuyasheshiswa. Ukuvimbela ukuqhekeka, kungcono ukusebenzisa amafutha. Okuwukuphela kwendlela isidakamizwa esibuhlungu ngayo umjovo, kunzima ukubekezelela ukwethulwa kwekhambi elingu-5.

Ukubuyekezwa kodokotela mayelana neTrental ne-Actovegin

I-Tikushin EA, i-neurosurgeon, i-Volgograd

I-Trental iyithuluzi elisebenzayo elisetshenziswa kabanzi kwi-neurology, inhliziyo, neurosurgery, angiology nakweminye imikhakha. Ama-Neurosurgeon anquma wona ezigulini ezinesilonda sohlelo lwezinzwa oluyingozi, i-craniocerebral trauma kanye ne-compression radiculopathy ngokumelene nesizinda somonakalo kuma-disc we-intervertebral disc.

Umuthi uyatholakala ngezindlela eziningi, ezilungele isiguli, ngoba inkambo emfushane yabantu abelahla kungaqhubeka ngokuthatha amaphilisi.

UBirin M.S., udokotela wezifo zemizwa, u-Ulyanovsk

I-Actovegin umuthi ongabizi futhi odumile wama-pathologies we-vascular ahlukahlukene. Inzuzo yayo phezu kwezidakamizwa zokwenziwa ukuphepha kwayo okuphezulu nemvamisa ephansi yokuphendula okungathandeki. Ukusebenza kanye nokuntuleka kwemiphumela yesikhathi eside yokuphatha kungabaza, ngoba umenzi akakuqinisekisanga ukusebenza ngempumelelo kwezidakamizwa ezifundweni zemitholampilo. Ngaphezu kwalokho, izinga lokuhlanzwa kwendawo yomthombo ngesikhathi sokukhiqiza nakho kuyakhathaza.