Kunezinto eziningi ezikhiqizwa ngomuthi i-Glucofage. E-Russia, isibonelo nguFomuetin noMetformin. Ngamandla esenzo bayefana.
Le mishanguzo yenzelwe abanesifo sikashukela. Zinokwakheka okufanayo futhi zihlobene nemithi yohlobo olwehlisa ushukela. Zingathengwa kuphela ngokubhaliwe. Yikuphi okungcono kusuka kuzidakamizwa, udokotela oholayo uyanquma, agxile esimweni, imiphumela yokuhlolwa nokuhlaziywa.
I-Metformin
Inefomu lethebhulethi lokukhishwa. Into esemqoka esetshenziswayo ekwakhiweni yindawo yokwakheka kwegama elifanayo. Kutholakala kwimithamo ye-500 ne-850 mg.
I-Metformin iqukethe into esemqoka esebenzayo yegama elifanayo.
Umuthi ungowesigaba sama-biguanides. Umphumela wemithi yesidakamizwa ubonakaliswa ngokuvimbela ukukhiqizwa kwe-glucose esibindini kanye nokunciphisa ukungena kwayo emathunjini. Umuthi awuthinti inqubo yokukhiqizwa kwe-insulini kuma-pancreas, ngakho-ke akukho bungozi bokusabela kwe-hypoglycemic.
Umuthi unomphumela omuhle ohlelweni lwezinhliziyo, uvimbela ukuthuthukiswa kwe-angiopathy kushukela.
Ngokuphathwa komlomo umuthi, ukuqoqwa okuphezulu kwesithako esikhulu esisebenza egazini kwenzeka ngemuva kwamahora ayi-2,5. Ukufakwa kwekhompiyutha kuyeka amahora ayi-6 ngemuva kokuthatha iphilisi. Ukuphila kwengxenye kwento kungamahora ayisikhombisa. I-Bioavailability ifinyelela ku-60%. Kuyakhishwa emchameni.
Izinkomba zokusetshenziswa kweMetformin - isifo sikashukela sezinhlobo zokuqala nezesibili. Umuthi ubekwe njenge-adjuvant yokwelapha nge-insulin kanye nokusetshenziswa kweminye imishanguzo, ngoba ukusebenzisana kwezidakamizwa kukhombisile imiphumela emihle. I-Metformin nayo ibekiwe njengethuluzi eliphambili ngesikhathi sokwelapha.
Umuthi usetshenziselwa ukukhuluphala, uma ufuna ukulawula amazinga kashukela egazini, inqobo nje uma ukudla kunganikezi umphumela omuhle. Omunye umuthi ungabekelwa ukutholakala kwe-ovary polycystic, kepha kulokhu, umuthi usetshenziswa kuphela ngaphansi kokuqokwa udokotela.
IFethethine
Umuthi uyatholakala ngesimo samaphilisi amhlophe okweqanda. Isithako esikhulu esisebenzayo yi-metformin.
Ithebhulethi eyi-1 iqukethe 500, 850 no-1000 mg wento. Umuthi wenzelwe ukusetshenziswa komlomo.
Umuthi ubekelwe abantu abanesifo sikashukela sohlobo 2 lapho ukudla kungasizi. Umuthi futhi usetshenziselwa ukunciphisa umzimba. Kuhlanganiswe ngempumelelo nokwelashwa kwe-insulin.
Ukuqhathaniswa kweMetformin neFormetin
I-Metformin ne-formin akuwona umuthi ofanayo. Ukunquma ukuthi iyiphi inketho engcono, kuyadingeka ukuqhathanisa imithi futhi unqume umehluko wawo, ukufana.
Ukufana
Akuwenzi mqondo ukukhetha ukuthi yisiphi isidakamizwa esingcono ngokuya ngezinkomba. Yomibili le mishanguzo inento efanayo esebenzayo ekwakhiweni nasekubonisweni kokusetshenziswa.
I-Metformin ne-formin zithathwa ngemithamo efanayo.
Amathebulethi akufanele ahlafunwe. Zidliwa zigcwele futhi zigezwa ngamanzi amaningi. Lokhu kwenziwa kangcono ngokudla nangemva kokudla. Inani lokwamukelwa ngosuku kuncike ekujuleni kwesimo sesiguli.
Ekuqaleni kokwelashwa, kubalwa i-1000-1500 mg ngosuku, ukuhlukanisa leli nani emgomeni ama-3. Ngemuva kwamaviki angu-1-2, umthamo ungashintshwa kuya ngokuthi kudingeka malini ukuze kubuyiswe izinga lokuhlungwa koshukela.
Kungenzeka ushintshele kwiMetformin noma iFomumetin kusuka kweminye imikhiqizo ye-analogue ngosuku 1 nje, ngoba akudingeki ukunciphisa umthamo obushelelezi.
Uma umthamo unyuswa kancane, khona-ke ukubekezelela umuthi kuzoba ngaphezulu, ngoba amathuba emiphumela emgudwini wokugaya ukudla ancipha. Umthamo ojwayelekile ngosuku ngu-2000 mg, kepha ngaphezu kwe-3000 mg kwenqatshelwe ukuthatha.
Kungenzeka ushintshele kwiMetformin noma iFomumetin kusuka kweminye imikhiqizo ye-analogue ngosuku 1 nje, ngoba akudingeki ukunciphisa umthamo obushelelezi. Kepha qiniseka ukuthi udla kahle.
Izidakamizwa zingathathwa ngesikhathi sokwelashwa kwe-insulin.
Kulokhu, umthamo wokuqala uzoba ngu-500-850 mg ngosuku. Hlukanisa konke ngezikhathi ezi-3. Umthamo we-insulin ukhethwa eselulekeni odokotela, ngokuya ngemiphumela yokuhlolwa kwegazi.
Ezinganeni, zombili lezi zinhlobo zemithi zivunyelwe ukusuka eminyakeni eyi-10. Ekuqaleni, umthamo ungama-500 mg ngosuku. Ungayithatha kanye ngosuku ngokudla kusihlwa. Ngemuva kwamaviki ama-2, umthamo uguqulwa.
Njengoba iMetformin neFormetin zinesithako esifanayo esisebenzayo, imiphumela yaso emibi iyafana. Vuka:
- izinkinga ngesistimu yokugaya ukudla, ehambisana nobuhlungu besisu, uhudo, isicanucanu, ukugabha, ukunambitheka kwensimbi emlonyeni, ukuthopha;
- ukusweleka kwamavithamini, ikakhulukazi i-B12 (maqondana nalokhu, iziguli zihlelwe ngokungeziwe ukulungiselela kwama-vithamini);
- ukusabela okwenziwa yizakhi zomuthi (kubonakaliswa ukuqhuma kwesikhumba, ubomvu, ukulunywa, ukucasuka);
- i-anemia
- i-lactic acidosis;
- kwehlisa ushukela wegazi ngezansi okujwayelekile.
Contraindication for Metformin neFormetin kufaka lokhu okulandelayo:
- okungamahlalakhona kanye nokuqina kwe-metabolic acidosis;
- i-glycemic coma noma isimo esiphambi kwaso;
- ukuphazamiseka kwesibindi;
- ukomisa kakhulu;
- umsebenzi wokuphazamiseka kwezinso;
- ukwehluleka kwenhliziyo kanye ne-myocardial infarction;
- izifo ezithathelwanayo;
- izinkinga ngemisele yokuphefumula;
- utshwala.
Ezinganeni, zombili lezi zinhlobo zemithi zivunyelwe ukusuka eminyakeni eyi-10.
Zombili lezi zidakamizwa azivunyelwe ukusetshenziswa ngaphambi kokuhlinzwa. Kuyadingeka ukulinda izinsuku ezi-2 ngaphambi nangemva kokuhlinzwa.
Uyini umehluko
Umehluko phakathi kweMetformin neFommetin kuphela kokutholakala ekwakhekeni kwamathebulethi. Yomibili le mikhiqizo iqukethe i-povidone, i-magnesium stearate, i-croscarmellose sodium, amanzi. Kepha iMetformin nayo iqukethe isitashi se-gelatinized ne-microcrystalline cellulose.
Izibhebhe zinegobolondo lefilimu, eliqukethe i-talc, i-sodium fumarate, udayi.
Lapho uthenga umuthi, kuyadingeka ukuthi unake okuqukethwe yizithako ezisizayo: lapho bezoba yincani, ngcono.
Yikuphi okushibhile
Kuzo zombili izidakamizwa, abakhiqizi yizinkampani ezifana neCanon, iRichter, iTeva ne-Ozone.
Umthamo wesithako esisebenzayo kwithebhulethi eyodwa ngu-500, 850 no-1000 mg lilinye. Ngentengo, bobabili iMetformin neFormetin cishe zisesigabeni esifanayo: eyokuqala ingathengwa eRussia ngentengo engaba ngama-ruble angama-105 ngephakeji lamathebhulethi angama-60, kuthi okwesibili, inani lizoba cishe ama-ruble angama-95.
Yini i-metformin noma i-formin engcono
Kuzo zombili izidakamizwa, isithako esiyisisekelo esisebenzayo yinto efanayo - metformin. Kulokhu, imiphumela yemithi iyefana. Ngaphezu kwalokho, lezi zimali ziyaguquguquka.
Udokotela ohlanganyelayo kuphela onganquma ukuthi yisiphi isidakamizwa esisebenza kahle esigulini ngasinye, kuye ngesimo.
Kulesi simo, ubudala, izici zomzimba ngamunye, isimo esivamile sesiguli, indlela nobukhali be-pathology ziyabhekwa.
Ngoshukela
Esikhathini sikashukela sohlobo lokuqala, lapho kukhona ukwephulwa okuphelele noma okuyingxenye ekwakhekeni kwe-insulin, iMetformin neFomumetin zisetshenziselwa ukunciphisa umthamo wokugcina, ukwengezelela ukwelashwa kwe-hormonal, ukushintshela ezinhlotsheni ezintsha ze-insulin (ukuze uphephe ngalesi sikhathi), futhi kuvikele nokukhuluphala.
Esikhathini sikashukela sohlobo lwesibili, izidakamizwa kumele ziphuzwe kaningi kakhulu. Bathuthukisa isimo esivamile sesiguli esisengozini yokulimala kakhulu kwe-insulin. Ngenxa yamathuluzi anjalo, amathuba okuthuthuka kwezinkinga zesifo sikashukela ancishisiwe.
Lapho wehlisa isisindo
IMetformin neFomuethine azithinti kuphela ushukela, kodwa futhi zehlisa izinga lama-lipoprotein, cholesterol ne-triglycerides egazini. Ngenxa yalokhu, asetshenziswa njengesengezo ngesikhathi sokudla. Konke ku-tata kunomthelela ekunciphiseni isisindo.
Ukubuyekezwa kweziguli
USergey, oneminyaka engu-38, eMoscow: "Kutholakale ukuthi isifo sikashukela sohlobo 2 sikashukela. Sekuphele unyaka ngithatha iMetformin ngifana nemijovo ye-insulin. Kuyasiza ukunciphisa ushukela wegazi kahle. Ngijabule ngomuthi, awuzange ube nemiphumela emibi."
U-Irina, oneminyaka engama-40, uKaluga: "IFomuethine etholwe njengokuyalelwa ngudokotela. Ushukela uvamile, kepha kunenkinga yokuthi ukukhuluphala. Ngaso leso sikhathi, ngaphendukela ekudleni okuphansi kwe-carb. Kusukela ngiqale ukwelashwa okuyinkimbinkimbi sengivele ngikwazi ukulahlekelwa ama-kg ayi-11. Isimo sami sesikhumba sesingcono."
Ngohlobo 2 sikashukela, izidakamizwa okukhulunywa ngazo kufanele ziphuzwe kaningi kakhulu.
Ukubuyekezwa kodokotela mayelana neMetformin neFommetin
UMaxim, i-endocrinologist, oneminyaka engama-38 ubudala, uSt. Petersburg: "Ngicabanga ukuthi iMetformin iyisidakamizwa esisebenzayo ekwelapheni i-endocrine system pathologies (isifo sikashukela i-mellitus, i-carbohydrate metabolism) .Kodwa ngasikhathi sinye, ngihlala ngixwayisa iziguli zami ngemiphumela emibi ejwayelekile. Lesi sidakamizwa singasetshenziswa njenge ngokuzimela nangokwelapha okuhlanganayo. "
U-Irina, udokotela we-endorinologist, oneminyaka engama-49, uKostroma: "IFormetin iyasebenza, futhi uma zonke izindlela zokuphepha zilandelwa, nayo iyisidakamizwa esiphephile. Ngaphandle kwalokho, ukuphazamiseka kwengqondo kwe-dyspeptic, kuvela uhudo. Lesi sidakamizwa esidala kakhulu sokwelapha isifo sikashukela."
