I-Tresiba yenzelwe ekwelapheni isifo sikashukela. Kusetshenziselwa ukuguqula amanani eglue. Inomphumela ophikelelayo ekulweni ne-hyperglycemia.
Igama Lezwe elingafanele
IsiLatini - iTresibum
I-Tresiba yenzelwe ekwelapheni isifo sikashukela.
I-ATX
A10AE06
Khipha amafomu nokwakheka
Kutholakala ngesimo sesixazululo somjovo - uketshezi olucacile, ngaphandle kokudaya kanye nanoma yikuphi ukungcola kwemishini. Into esemqoka esebenza yi-insulin degludec 100 IZITHOMBE. Izakhi ezingeziwe zethulwe: i-metacresol, i-glycerin, i-phenol, i-hydrochloric acid, i-zinc acetate, i-dihydrate, i-sodium hydroxide namanzi wokujova.
Kuyi-polypropylene syringe pen kukhona i-cartridge enesixazululo somjovo ku-3 ml, i.e. Ama-300 PIECES we-insulin degludec. Ingilazi isetshenziselwa ukwenza i-cartridge. Kukhona i-piston enjoloba ngakolunye uhlangothi lwe-cartridge ne-disc yerabha ngakolunye. Iphakethe lamakhadibhodi liqukethe amapeni ezinjinji ezinjenge-5.
Isenzo se-Pharmacological
I-insulin ye-Degludec inamandla okubamba indawo yonke ngokushesha ukubopha i-insulin yomuntu. Ngakho-ke, umphumela wokwelapha walezi zinhlobo ze-insulin ucishe ufane. Ama-insulin receptors abopha kuma-receptors athile asemafutheni amaseli wamafutha nemisipha. Ngasikhathi sinye, i-insulin ayigcini ngokuba nomphumela we-hypoglycemic, kodwa futhi ivimbela ukukhishwa kweglucose esibindini.
Kuyi-polypropylene syringe pen kukhona i-cartridge enesixazululo somjovo ku-3 ml, i.e. Ama-300 PIECES we-insulin degludec.
Umuthi uthathwa njenge-basal insulin. Ngemuva kokwethulwa kwayo, kwakhiwa i-multihexamer ethile. Ukusuka kwidepho eyakhiwe, i-insulin yamahhala ingena egazini. Amazinga kashukela wegazi ancipha kancane. Kepha isenzo sihlala isikhathi eside ngokwanele.
I-Pharmacokinetics
Ngemuva kokuphathwa ngqo kwesidakamizwa se-insulin, kudalwa idepho enobuhlakani. Ama-insulin monomers aqala ukuhlukana kancane kancane nama-multihexamers. Ngenxa yalokhu, i-insulin, yize ihamba kancane kodwa njalo, ingena egazini. Inani elikhulu kakhulu ku-plasma libonwa amahora ambalwa ngemuva komjovo. Umphumela uhlala izinsuku ezi-2.
Umuthi usatshalaliswa kahle futhi ucishe usatshalaliswa ngokulinganayo kuwo wonke izicubu nezitho zomzimba. I-Bioavailability kanye namandla okubopha ezinhlakeni zamaprotheni ziphakeme impela. Akukho neyodwa yama-metabolites aphumelelayo enezinto ezisebenzayo. Ukuphila kwesidakamizwa kuthatha cishe amahora angama-25.
Izinkomba zokusetshenziswa
Izinkomba zokusetshenziswa kwomuthi, njengoba kuboniswa ngumyalo, ukwelashwa kwesifo sikashukela kubantu abadala, intsha nasebantwaneni kusukela ngonyaka owodwa.
Izinkomba zokusebenzisa umuthi, njengoba kuboniswa ngumyalo, ukwelashwa kwesifo sikashukela.
Contraindication
Ukuphulwa okuqondile kokusetshenziswa kukhona:
- ukukhulelwa
- inkathi yokuhlanza;
- iminyaka yezingane kuze kube unyaka 1;
- hypersensitivity kuzakhi zomuthi.
Ungayithatha kanjani iTreshiba?
I-Treshiba FlexTouch isetshenziselwa injekishini engaphansi. Imijovo kufanele inikezwe kanye ngosuku, mhlawumbe nsuku zonke ngasikhathi sinye. Umthamo ukhethiwe ngokuhlukile. Kuyadingeka ukwengeza ukulawulwa kwe-glycemic ngokusekelwe kushukela we-glucose. Ipeni lesirinji likuvumela ukuthi ufake amayunithi we-1-80 wemithi isikhathi esingu-1.
Ungayisebenzisa kanjani ipeni yesirinji?
Ngaphambi kokusebenzisa, qiniseka ukuthi uhlola ipeni lesirinji ukuze lisebenze kahle. Kufanele uqiniseke ukuthi iqukethe uhlobo lwe-insulin kanye nenani elidingekayo lomjovo. I-cap yokuvikela isuswa kwisirinji. Ngemuva kwalokho thatha inaliti ususe ulwelwesi lwephepha lokuvikela.
I-Treshiba FlexTouch isetshenziselwa injekishini engaphansi.
Inalithi ihlephuke isibambo. Isigaxa sangaphandle sisuswa ngenalithi kepha singaphonswa sivale inalithi esetshenzisiwe ngemuva komjovo. Futhi ithumba elingaphakathi liyalahlwa. Izinaliti zidonswa ngemuva komjovo ngamunye. Ipeni lesirinji ligcinwa isikhathi eside, kepha isikhathi ngasinye lapho livaleka ngesicubu esivikela ukuvikela noma yikuphi ukutheleleka ekungeneni kulo.
Ukuthatha umuthi wesifo sikashukela
Kubantu abanohlobo lwe-2 pathology, lo muthi uphathwa ngokuhlukile noma ngokuhlanganiswa nezidakamizwa ezinciphisa ushukela ukuphathwa komlomo, noma i-bolus insulin.
Umthamo wokuqala ophakanyisiwe amayunithi ayi-10 ngosuku ngokulungiswa komthamo okwalandela. Iziguli ezithole i-insulin ngokweqile noma nge-basal-bolus insulin, kanye nalabo abaxube i-insulin, zishintshela kuTreshiba 1: 1 kudosi yangaphambilini ye-insulin.
Ezigulini ezinomdlavuza wesifo sikashukela sohlobo 1, umuthi kanyekanye une-insulin emfushane ukumboza isidingo sawo ngenkathi udla. Umuthi ufakwa kanye ngosuku kanye ne-insulin.
Ezigulini eziningi ezinesifo sikashukela sohlobo 1, ukuguquka kusuka ku-insal insulin kuya eTreshiba kwenzeka ngesilinganiso esingu-1: 1. Kubantu abathola i-insal insulin kabili ngosuku, umthamo wokuguqula ubalwa ngawodwana. Ukwehliswa kwedosi kubheka impendulo ye-glycemic.
Imiphumela emibi iTreshiba
Thuthukisa njengokweqisa umthamo noma ukwephula irejimeni lomjovo.
Uma kuthathwa, imiphumela yokungezwani komzimba ingenzeka.
Kusuka emasosheni omzimba
Uma kuthathwa, imiphumela yokungezwani komzimba ingenzeka. Ukuvezwa kwabo okunzima kuvame ukusongela impilo. Zingavezwa ngokuvuvukala kwezindebe nolimi, isifo sohudo, isicanucanu, ukulunywa, i-malaise ejwayelekile.
Engxenyeni ye-metabolism kanye nokudla okunempilo
I-Hypoglycemia ivame ukukhula. Kwenzeka lapho umthamo we-insulin utholiwe uphakeme kakhulu kunesidingo. Izimpawu ze-hypoglycemia zenzeka ngokuzumayo. Babonakaliswa izithukuthuku ezibandayo, isikhumba esimpunga, ukukhathazeka, ukuthuthumela, ubuthakathaka obujwayelekile, ukudideka, ukukhuluma okulimazayo nokuxineka, indlala eyandayo, ikhanda, umbono ophansi.
Engxenyeni yesikhumba
Ukusabela kwesikhumba okuvame kakhulu yi-lipodystrophy, engakhula endaweni yomjovo. Ingozi yokuqhamuka nemiphumela enjalo izokwehla uma isiza somjovo siguqulwa njalo.
Allergies
Ngokufakwa komuthi, ukuvela kungavela endaweni yomjovo. Ziyavela: i-hematomas, izinhlungu, ukulunywa, ukuvuvukala, ukubukeka kwamaqhubu kanye ne-erythema, ukuxinana kwabantu kule ndawo. Konke lokhu kwenzeka ngenxa yokuthi ama-antibodies athile akhiqizwa ukuphendula ukuphathwa komuthi. Ukusabela okunjalo kuguqukeleka emuva, ngokulingana, akudingi ukwelashwa okukhethekile futhi ekugcineni kudlule ngokwabo.
Ukusabela kwesikhumba okuvame kakhulu yi-lipodystrophy, engakhula endaweni yomjovo.
Umthelela ekhonweni lokulawula izindlela
Ngoba ngesikhathi sokwelashwa i-hypoglycemia ingaqhamuka, ukunakekelwa okukhethekile kumele kuthathwe lapho ushayela nezinye izindlela eziyinkimbinkimbi ezidinga ukunakwa okwandayo kokunakwa.
Imiyalo ekhethekile
Uma usebenzisa lesi sidakamizwa, udinga ukubhekisisa njalo amazinga kashukela egazini ukugwema ukuthuthukiswa kwezinkinga ezingakhona. Kulesi simo, ipeni lesirinji lisebenzisa kanye kuphela. Awukwazi ukuxuba izinhlobo eziningana ze-insulin ku-1 syringe.
Sebenzisa ebudaleni
Kubantu asebekhulile, ingozi yokwanda kwe-hypoglycemia iyanda. Ngakho-ke, ukusetshenziswa kwezidakamizwa kuleli qembu leziguli kudinga ukubhekwa njalo kwezinguquko emiphumeleni yokuhlola.
Kunquma uTreshiba ezinganeni
Ngokusho kosokhemisi, lesi sidakamizwa singasetshenziswa ebusheni nasebantwaneni kusukela ngonyaka owodwa.
Ngokusho kosokhemisi, lesi sidakamizwa singasetshenziswa ebusheni nasebantwaneni kusukela ngonyaka owodwa.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Leli thuluzi lingasetshenziswa ngesikhathi sokukhulelwa. Kepha kufanele ubheke njalo imiphumela yezinguquko ekugxambeni kwe-glucose egazini. Lokhu kuyiqiniso ikakhulukazi kwabesifazane abakhulelwe abanesifo sikashukela. Ekuqaleni kokukhulelwa, isidingo se-insulin sincishisiwe, kuthi ekugcineni kwethemu kukhuphuke. Ngakho-ke, kubalulekile ukuqapha ukuguquguquka kushukela wegazi ukuvimbela ukuthuthukiswa kwe-hypoglycemia.
Akukho zifundo zokuthi ingabe into esebenzayo idlulela ebisini lwebele. Kodwa ngokusho kweminye imibiko, azikho izehlakalo ezimbi eziqashelwa enganeni.
Isicelo sokusebenza kokulimala kwezinso
Konke kuncike ekuthini imvume ye-creatinine. Lapho iphakeme, yehlisa umthamo we-insulin okudingeka uyisebenzise.
Sebenzisa umsebenzi wesibindi okhubazekile
Kukhona ingozi enkulu yezinkinga ngesikhathi sokwelashwa ngezidakamizwa ze-insulin. Ngakho-ke, ukunakekelwa kufanele kuthathwe ukulawula amazinga kashukela.
Kukhona ingozi enkulu yokuthola izinkinga zesibindi ngesikhathi sokwelashwa ngezidakamizwa nge-insulin.
Ukweqisa kweTreshiba
Uma ufaka umthamo owandayo, kuvela i-hypoglycemia yamazinga ahlukahlukene. I-hypoglycemia emnene iphathwa nge-glucose noma ukudla okuqukethe ushukela kanye nama-carbohydrate asheshayo. Ezimweni ezibucayi, lapho isiguli siphelelwa amandla, i-glucagon ifakwa emsipha noma ngokunqenqema. Uma ngemuva kwemizuzu engama-20 isimo singashintshi, kufakwe isisombululo seglucose emthanjeni.
Ukuxhumana nezinye izidakamizwa
Ezinye izidakamizwa zinciphisa kakhulu isidingo somzimba se-insulin. Phakathi kwazo: izidakamizwa ezinciphisa ushukela ngomlomo, ama-inhibitors we-MAO, ama-beta-blockers, ama-inhibitors e-ACE, amanye ama-salicylates, ama-sulfonamides nama-anabolic steroid.
Ukwanda kwesilinganiso se-insulin kuyadingeka lapho kuthathwa ndawonye nama-thiazides, izidakamizwa ze-glucocorticosteroid, KULUNGILE, ama-sympathomimetics, i-thyroid kanye ne-hormone yokukhula, iDanazole.
Ukuhambisana notshwala
Awukwazi ukuhlanganisa ukuphuza umuthi notshwala. Lokhu kuholela ku-hypoglycemia enzima, engathinta isimo jikelele sesiguli.
Ama-Analog
Izidakamizwa ezithatha lezi:
- I-Aylar;
- I-Lantus Optiset;
- ILantus;
- ILantus Solostar;
- Tujeo;
- Tujeo Solostar;
- Levemir Penfill;
- Levemir Flekspen;
- I-Monodar;
- Solikva.
Imibandela yekhefu lekhemisi
Umuthi ungathengwa ekhemisi ngemithi.
Ngingakwazi ukuthenga ngaphandle kadokotela?
Kukhishwe.
Intengo yaseTreshiba
Izindleko ziphakeme futhi zifinyelela kuma-ruble angama-5900-7100. iphakethe ngalinye lama-cartridge angama-5.
Izimo zokugcina zomuthi
Ukuqandeka kufanelekile njengendawo yokugcina, inkomba yokushisa - + 2 ... + 8 ° C. Musa ukubanda. Ipeni lesirinji kufanele ligcinwe kuphela lapho isivalo sivaliwe. Ngemuva kokuvulwa kokuqala, ipeni lesirinji lingagcinwa emazingeni okushisa angeqi ku-30 ° C, asetshenziselwe amaviki ayi-8.
Isikhathi sokuphelelwa yisikhathi
Iminyaka engu-2,5.
Umkhiqizi
Inkampani yezokukhiqiza: A / S Novo Nordisk, eDenmark.
Ukubuyekezwa mayelana neTresib
Odokotela
UMoroz A.V., i-endocrinologist, iminyaka engama-39, uYaroslavl.
Manje saqala ukuqoka iTreshib hhayi kaningi, ngoba Intengo yayo iphakeme ngokweqile, akuzona zonke iziguli ezingakwazi ukuthenga lokho. Futhi ngakho-ke umuthi muhle futhi uyasebenza.
I-Kocherga V.I., i-endocrinologist, eneminyaka engama-42, uVladimir.
Naphezu kwezindleko eziphakeme, ngikweluleka iziguli zami ukuthi zikhethe lo muthi, ngoba kangcono kunesizukulwane esisha se-insulin, angikaze ngihlangane. Ugcina kahle ushukela kahle, ngomjovo owodwa ngosuku.
Isifo sikashukela
U-Igor, oneminyaka engama-37 ubudala, uCebokary.
Nginesifo sikashukela sohlobo 1. Ngokunconywa ngudokotela, ngilandela ukudla nokugwazwa kweziyunithi eziyi-8 zaseTreshiba ebusuku nangaphambi kokudla nge-Actrapid. Ngiyayithanda imiphumela. Ushukela uvamile usuku lonke, akukaze kube nokuhlaselwa kwe-hypoglycemia isikhathi eside.
UKarina, oneminyaka engama-43 ubudala, u-Astrakhan.
Bengihlala ngithatha iLevemir, ngeqa ushukela omncane, bese ngiyalwa ukuba ngishintshele eTresiba. Izinga likashukela libuyele kwelejwayelekile, ngigculisekile ngemiphumela yomuthi. Kepha kukhona okukodwa okukhulu - kuyabiza, futhi akuwona wonke umuntu ongakukhokhela.
UPavel, oneminyaka engama-62 ubudala, Khabarovsk.
Lesi sidakamizwa sathathwa unyaka. Manje udokotela wangidlulisela eLevemir, ngoba Kubiza kakhulu eshibhile. Kubi kakhulu, kuyadingeka ukunitha cishe ngaphambi kokudla ngakunye.
