IGalvus 500 kwifomu lethebhulethi ikhonjiswa ezigulini ezinezimpawu ezinzima zesifo sikashukela. Umuthi ezimweni ezingandile ubangela imiphumela emibi, kepha akufanele usebenzise umuthi noma kumthamo omncane ngaphandle kokuyalelwa ngudokotela ukuze ugweme izinkinga.
Igama Lezwe elingafanele
IVildagliptin + metformin - amagama ezinto ezisebenzayo zomuthi.
IGalvus 500 kwifomu lethebhulethi ikhonjiswa ezigulini ezinezimpawu ezinzima zesifo sikashukela.
I-ATX
I-A10BH02 - ikhodi yokuhlukaniswa kwamakhemikhali okwelashwa nokwelashwa.
Khipha amafomu nokwakheka
IGalvus Met iyatholakala ngesimo samathebhulethi ama-7 noma ama-14 ama-PC. ekufakweni kweseli.
Ithuluzi elisetshenziselwa ukusetshenziswa komlomo.
Okuqukethwe kwe-vildagliptin kuthebhulethi engu-1 ngu-50 mg, kuthi i-metformin ingu-500 mg.
Isenzo se-Pharmacological
Umuthi ungowenombolo yama-hypoglycemic agents, afaka izingxenye ezi-2 ezisebenzayo ezinamasu ahlukile wokusebenza kokulashwa. Ngaphezu kwalokho, i-vildagliptin iyi-inhibitor ye-dipeptidyl peptidase-4 (DPP-4), futhi i-metformin hydrochloride ingeqembu le-Biguanides. Ekwelashweni okuhlanganisiwe, lezi zinto ziqapha izinga le-glucose yegciwane ezigulini ezinesifo sikashukela esingavikelekile i-insulin (uhlobo 2) amahora angama-24.
Ukuphuza amaphilisi kunomthelela ekunciphiseni kancane kancane kokuhlushwa ushukela wegazi, futhi naphikisana nesizinda sezimpawu ezinhle zeklinikhi, akunqabile ukuthi kwenzeke izimo zokuthuthuka kwesimo se-pathological esibonakaliswa izinga le-glucose engaphansi kuka-3.5 mmol / l, igazi le-peripheral under tloaelehileng (3.3 mmol / l) .
I-Pharmacokinetics
Ukudla ngezinga elincane kuthinta ukumuncwa kwezingxenye ezisebenzayo, kepha ukuqoqwa kwezinto ezisebenzayo akufinyeleli esikalini sazo. Uma uphuza amaphilisi esiswini esingenalutho, khona-ke ngemuva kwehora kunokuqukethwe okuphezulu kwezinto ezisebenzayo ku-plasma yegazi.
Uma uphuza amaphilisi esiswini esingenalutho, khona-ke ngemuva kwehora kunokuqukethwe okuphezulu kwezinto ezisebenzayo ku-plasma yegazi.
Imikhiqizo yokuwohloka iyadedelwa umchamo nenani elincane lokungcwaba. I-bioavailability (ikhono lesidakamizwa ukutholwa) yezinto okungenani i-80%.
Izinkomba zokusetshenziswa
Umuthi unqunywe ezimweni ezinjalo:
- i-monotherapy ene-vildagliptin noma i-metmorphine ayizange iholele kumphumela oyifunayo wokwelapha;
- ukungasebenzi kahle kokulashwa kokudla kuqhathaniswa nesizinda sokulahlekelwa isisindo;
- Ukwehluleka lapho uzama ukulawula ushukela wegazi ngezinye izindlela zokwelashwa.
Nge-Type 1 sikashukela mellitus, umuthi awusetshenziswa.
Contraindication
Awukwazi ukusebenzisa umuthi ezimweni:
- ukungabekezelelani ngakunye kwezinto ezisebenzayo;
- ukomisa komzimba;
- izinqubo zokutheleleka nokuvuvukala kwama-etiologies ahlukahlukene;
- umkhuhlane
- okuqukethwe okungaphansi komoya-mpilo emzimbeni noma izitho zomuntu ngamunye nezicubu;
- uhlobo olungamahlobo lokudakwa kanye nefomu elibi lokudakwa komzimba ngotshwala;
- ukunamathela ekudleni okuphansi kwekhalori.
Indlela engalapheki yotshwala iwukuphikisana nokusetshenziswa kwomuthi.
Ungamthatha kanjani uGalvus 500
Kubalulekile ukulandela imiyalo esetshenzisiwe.
Ngoshukela
Kunezici eziningi ezinjalo:
- Umthamo womuthi usethwa ngudokotela ngokwahlukana, kuyilapho inani le-vildagliptin elisetshenzisiwe akufanele lidlule i-0,1 g.
- Ukuze ugweme imiphumela emibi, umuthi uphuzwa kangcono ngokudla.
- Baqala ukwelashwa ngethebhulethi eyi-1 kabili ngosuku, khona-ke umthamo ungandiswa.
Imiphumela emibi yeGalvus 500
Engxenyeni yesitho sombono
Mhlawumbe ukwehla kwamandla okubuka kanye nokunye ukungaboni kahle.
Kusuka ezicutshini zemisipha
Ubuhlungu emalungeni buyaqapheleka.
Amapheshana wesisu
Ngesinye isikhathi, i-stool disorder ivela, futhi iziguli zikhononda ngokuhlanza.
Izitho zeHematopoietic
Ukuphendula okungathandeki akuvamile ukubonwa.
Isistimu yezinzwa ephakathi
Imvamisa kuba khona isiyezi nokuthuthumela kwemilenze ephezulu.
Kusuka ohlelweni lomchamo
Mhlawumbe ukuchama okusheshayo, okuhambisana nokuzwa kobuhlungu.
Kusuka ohlelweni lokuphefumula
Ukudangala okuphefumulayo akuzange kubhalwe phansi.
Engxenyeni yesikhumba
Ukuqhuma kungenzeka.
Ngesinye isikhathi, ngenkathi uphuza umuthi, ukungabi namandla kocansi kuyabonakala.
Kusuka ohlelweni lwezitho zofuzo
Ngesinye isikhathi, ukungabi namandla kuyabhekwa.
Kusuka ohlelweni lwezinhliziyo
Kwesinye isikhathi kuba nokushaya kwenhliziyo okusheshayo.
Allergies
Ukushaqeka kwe-Anaphylactic kuyinto ebonakalayo ezigulini ezine-hypersensitivity kuzakhi ezisebenzayo.
Umthelela ekhonweni lokulawula izindlela
Kufanele wenqabe ukushayela imoto nemisebenzi yobungcweti ehlotshaniswa nokunakwa okuninginingi kokunakwa.
Imiyalo ekhethekile
Kubalulekile ukucabanga ngezici eziningi lapho usebenzisa lo muthi.
Sebenzisa ebudaleni
Akunconyelwe ukunquma umuthi ezigulini ezineminyaka engaphezu kwengu-60 uma zizikhandla ngokomsebenzi emsebenzini, njengoba kuba khona njalo kwe-lactic acidosis.
Lesi sidakamizwa sifakwa kubantu abangaphansi kweminyaka engu-18 ubudala.
Isabelo sezingane
Ungasebenzisi umuthi weziguli ezingaphansi kweminyaka yobuningi.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Ezifundweni zokuhlola, lapho zisetshenziswa kumthamo ophindwe izikhathi ezingama-200 kunokunconywa, umuthi awuzange ubangele ukuzala okungasebenzi kahle kanye nokukhula kokuqala kwe-umbungu futhi awuzange ube nemiphumela emibi ye-teratogenic.
Ngesikhathi sokuncelisa, kungcono ukwenqaba ukwelashwa nge-Galvus.
Isicelo sokusebenza kokulimala kwezinso
Sebenzisa ngokuqapha uma wehluleka wezinso.
Sebenzisa umsebenzi wesibindi okhubazekile
Ukulungiswa komthamo kuyadingeka.
Ukweqile kweGalvus 500
Uma umthamo we-vildagliptin udluliwe, ubuhlungu bemisipha nomkhuhlane kuyabonakala.
Nge-overdose ye-metformin, ukwanda kokushisa komzimba kungenzeka.
Nge-overdose ye-metformin, isicanucanu, isisu, kanye nokwehla kwezinga lokushisa lomzimba kungenzeka. Ukwelashwa okubonakalayo kuyadingeka.
Ukuxhumana nezinye izidakamizwa
Kubalulekile ukucubungula okulandelayo:
- Ngokusebenzisa kanyekanye i-insulin, imvamisa yokuhoxiswa kweGalvus ngenxa yokuqhamuka nemiphumela emibi yayingaphansi kuka-0.5% eqenjini le-vildagliptin, ngenkathi eqenjini le-placebo bezingekho amacala okuhoxiswa kwempatho.
- Ngokusetshenziswa okuhlanganisiwe kweGalvus nezinye izidakamizwa ekwelapheni isifo sikashukela sohlobo 2, akukho ukusebenzisana okwashiwo ngokomtholampilo.
- Ukusetshenziswa kwe-furosemide kusheshisa ukumuncwa kwe-metformin.
- Ama-diuretics nezindlela zokuvimbela inzalo ngomlomo anciphisa ukusebenza komphumela wokwelapha womenzeli we-hypoglycemic.
- Ukwelashwa nge-antipsychotic kudinga ukulungiswa kwamthamo kanye nokulawulwa kokuhlushwa kashukela egazini.
- Ukuhlanganiswa kwezidakamizwa ezine-iodine equkethe i-iodineque kukhuthaza i-lactic acidosis kanye nokuqhubekela phambili kokungasebenzi kahle kwezinso.
- I-β2-sympathomimetics engangeneki inyusa ushukela wegazi ngenxa yokuvuswa kwama-receptors we-β2.
Ukuhambisana notshwala
Ukusetshenziswa kotshwala kuyaphikiswa ukuze kugwenywe ukwanda kwemiphumela emibi.
Ukusetshenziswa kotshwala kuyaphikiswa ukuze kugwenywe ukwanda kwemiphumela emibi.
Ama-Analog
Ukusebenza kahle nokuphepha kokusetshenziswa nakho kuyimpawu yeGlibomet ne-Gluconorm.
Imibandela yekhefu lekhemisi
Ngingakwazi ukuthenga ngaphandle kadokotela
Kuvunyelwe ukuthengisa umuthi ngaphandle kadokotela.
Intengo
Izindleko zomkhiqizo okungenani ngama-ruble ayi-1200.
Izimo zokugcina zomuthi
Ungasigcina isidakamizwa emazingeni okushisa asekamelweni.
Isikhathi sokuphelelwa yisikhathi
Umuthi ugcina izindawo zawo zokuphulukisa iminyaka emi-2.
Umkhiqizi
Lo mkhiqizo ukhiqizwa yinkampani yaseJalimane iNovartis Pharma Production GmbH.
Ukubuyekezwa
Odokotela
UYuri, oneminyaka engama-43 ubudala, eMoscow
Ngokuphikisana nesizinda sokusetshenziswa kweGalvus, ukwehla kwezinga le-lipids egazini kuyaphawulwa. Ezimweni eziningi, ngibeka umuthi wokwelapha iziguli ezine-pathology ezisanda kutholwa, noma ngabe sikhuluma ngabesifazane abakhulelwe. Umuthi uyasiza ukwenza impilo ibe njalo ngaphakathi kwamasonto amabili.
U-Oleg, oneminyaka engama-50 ubudala, eSt
Kufanele sinikeze ama-analogues ashibhile, ngoba Izindleko zikaGalvus ziphezulu, yize isebenza kahle. Ngincamela ukwelashwa okugcwele kwalesi sifo, okubandakanya ukunamathela ezimisweni zokudla okunempilo.
Kuvunyelwe ukuthengisa umuthi ngaphandle kadokotela.
Isifo sikashukela
U-Alla, oneminyaka engama-25, u-Omsk
Ngikuthandile ukusetshenziswa kalula kwamathebulethi. Kepha ngahlangabezana nesiyezi nokuhlanza kanzima ngosuku lwesithathu ngiphuza umuthi. Udokotela uphakamise ukuthi uthathe ikhefu, bese eqala ukwelashwa. Umphumela wokwelashwa waneliswa.
UMaxim, oneminyaka engama-40 ubudala, uPm
Ngaphuza amaphilisi inyanga yonke. Amazinga kashukela wegazi ajwayelekile, futhi futhi waphawula ukwehla kwesisindo somzimba. Udokotela ukhansele i-insulin ngesikhathi sokwelashwa noGalvus. Intengo yamaphilisi kuphela engahambanga, kepha ayincomanga ukuthatha i-analogue.
