I-insulin ye-hormone ihlanganiswe futhi ithunyelwe ngamanyikwe. Lapho amaseli awo ehluleka ukuhlanganisa kahle i-insulin ngokwanele, kuvela isifo esifana nohlobo lwesifo sikashukela. Ushukela omningi, onqwabelana egazini, uyingozi emzimbeni. Enye yezidakamizwa ezisetshenziselwa ukunxenxa ukushoda kwe-insulin yi-Insugen R.
Igama Lezwe elingafanele
I-Insulin (yomuntu) (Insulin (yomuntu)).
Enye yezidakamizwa ezisetshenziselwa ukunxenxa ukushoda kwe-insulin yi-Insugen R.
I-ATX
I-A10AB - I-Insulin kanye nezimpawu zomjovo, ukuthatha isinyathelo ngokushesha.
Khipha amafomu nokwakheka
Ukumiswa komjovo, 40 MO / ml, ngo-10 ml emabhodleleni uNo, 10, no-20, Cha. 50, No. 100.
Ukumiswa komjovo, i-100 MO / ml, ngo-10 ml emabhodleleni uNo. 10, Cha. 20, Cha. 50, No. 100, 3 ml kumabhokisi wemoto No. 100.
Isenzo se-Pharmacological
Isixazululo se-insulin somuntu omfushane.
I-insulin ilawula umsoco we-glucose emzimbeni. Le-hormone yehlisa inani le-glucose egazini ngokuvusa ukuthathwa kwe-glucose amaseli omzimba (ikakhulukazi izicubu zomzimba kanye namafutha izicubu) futhi ivimbe ne-gluconeogeneis (synthesis glucose esibindini).
Ezigulini ezinesifo sikashukela i-mellitus, umuthi unesandla enkambweni efanele yazo zonke izinqubo, wehlisa ubungozi bezinkinga ezenzeka ngalesi sifo.
Lapho usebenzisa umuthi, kufanele ubheke njalo amazinga kashukela egazini.
I-Pharmacokinetics
Umuthi uqala ukusebenza kungakapheli imizuzu engama-30. Umphumela omkhulu ubonwa ngemuva kwamahora we-2-4. Isikhathi sokusebenza: kusuka emahoreni amane kuya kwayi-6.
Isikhathi sokuphila se-insulin egazini siyimizuzu eminingana. Lokhu kuthonywa yizici eziningi: umthamo we-insulin, indawo yomjovo.
Izinkomba zokusetshenziswa
Ukwelashwa kwesifo sikashukela mellitus uhlobo 1 no-2.
Umuthi usetshenziselwa uhlobo 1 lwesifo sikashukela.
Contraindication
Isimo se-hypoglycemia. I-Hypersensitivity yesiguli kuya ku-insulin noma kwesinye isakhi somuthi.
Ngokunakekela
Ukuqapha kuyadingeka lapho usebenzisa umuthi kwabesifazane abakhulelwe (idatha eyanele ekusetshenzisweni ngesikhathi sokukhulelwa).
Akukaziwa ukuthi i-insulin ikhishwa ubisi lukamama. Lapho ukuncelisa ibele, ukulungisa imithamo yomuthi nokudla kwesinye isikhathi kuyadingeka.
Ungayithatha kanjani i-Insugen R
Kufakelwa ngaphansi kwesikhumba ezicutshini ze-adipose zesisu, ethangeni noma ehlombe. Ukuze i-lipodystrophy ingakhuli, isayithi lomjovo kufanele liguqulwe emjovo ngamunye.
Uma kuqhathaniswa nemijovo kwezinye izingxenye zomzimba, umuthi udonswa ngokushesha lapho kungeniswa izicubu zesisu se-adipose.
Umuthi ufakwa ngaphansi kwesikhumba ungene kwezicubu ze-adipose zesisu, ithanga noma ehlombe.
Umuthi awuvunyelwe ukungena emthanjeni.
Ngoshukela
Umthamo wesidakamizwa uyahluka phakathi kwe-0.5-1 IU / kg ngosuku futhi ubalwa ngawodwana, ucabanga ngezinga le-glucose egazini lesiguli ngasinye.
Umuthi uphathwa izikhathi ezi-1-2 ngosuku, isigamu sehora ngaphambi kwesidlo esinokuqukethwe kwe-carbohydrate ephezulu.
Ukushisa kwekhambi elifakiwe kufanele kube + 18 ... + 25 ° C.
Ngaphambi kokujova, udinga:
- Qinisekisa ukuthi iziqu ezikhonjiswe kwisirinji zilingana ne-insulin eprintiwe ku-vial: 40 IU / ml noma i-100 IU / ml.
- Sebenzisa i-syringe kuphela nge-graduation elingana ne-insulin ye-vulin.
- Sebenzisa uboya bekotoni ofakwe utshwala bezokwelapha ukuze ukhubaza i-vial.
- Ukuze uqiniseke ukuthi isixazululo esisebhodleleni siyabonakala futhi akukho okunye ukungcola kuso, udinga ukusinyakazisa kancane. Uma ukungcola kukhona, umuthi awulungele ukusetshenziswa.
- Qoqa umoya omningi ku-syringe njengoba uhambelana nomthamo ophethwe we-insulin.
- Ngenisa umoya kwi-vial yomuthi.
- Nyakazisa ibhodlela bese udonsa inani elifanele le-insulin esitokisini.
- Bheka umoya ku-syringe kanye nethamo elifanele.
Oda kwesingeniso:
- udinga ukusebenzisa iminwe emibili ukudonsa isikhumba, ufake inaliti ngaphansi kwawo bese ufaka umuthi;
- gcina inaliti ngaphansi kwesikhumba imizuzwana eyi-6 futhi uqiniseke ukuthi okuqukethwe isirinji kufakiwe ngaphandle kokusalayo, kuhoxise;
- lapho wabela igazi kusuka endaweni yomjovo ngemuva komjovo, cindezela le ndawo ngocezu loboya bekotini.
Uma i-insulin ikwelamabhange, lapho-ke kufanele usebenzise ipeni lesirinji elikhethekile ngokuya ngemiyalo yalo yokusebenzisa. Ukusetshenziswa kabusha kwekhabethe kuyenqatshelwe. Ipeni elilodwa lesirinji kufanele lisetshenziswe ngumuntu oyedwa kuphela. Kuyadingeka ukulandela ngokucophelela imiyalo yokusebenzisa ipeni lesirinji.
Imiphumela emibi ye-Insugen R
Lapho usebenzisa umuthi, imiphumela emibi eminingana ingavela:
- ezihambisana ne-carbohydrate metabolism: i-hypoglycemia (ukumamatheka ngokweqile, ukukhubazeka ngokweqile kwesikhumba noma ukwethuka, ukuncipha kokuxineka, ukukhathazeka, ukukhathala noma ubuthakathaka, isiyezi, indlala enkulu, isicanucanu, ukukhuphuka kwenhliziyo; ukwazi;
- izinkinga ze-allergic: kaningi - i-urticaria, ukuqubuka esikhunjeni, kuyaqabukela - i-anaphylaxis;
- ukusabela kwendawo ngesimo sokungezwani komzimba (ubomvu kwesikhumba, ukuvuvukala, ukulunywa endaweni yomjovo), imvamisa phakathi nesikhathi sokwelashwa bayazivimba, i-lipodystrophy ivame ukuvela;
- abanye: ekuqaleni kokwelashwa, kuyaqabukela - i-edema ehlukahlukene, kwenzeka iphutha elingajwayelekile.
Lapho usebenzisa i-insulin, imiphumela emibi ikhula ngokuya ngethamo futhi kungenxa yesenzo se-insulin.
Umthelela ekhonweni lokulawula izindlela
I-hypoglycemia eholelwayo ingaholela ekuwohlokeni kwekhono lokushayela imoto futhi iphazamise eminye imisebenzi emibi emisebenzini eyingozi, edinga ukunakwa okwengeziwe nokuphendula okusheshayo kwengqondo nemoto.
Imiyalo ekhethekile
Ezinye iziguli zidinga ukulandela imithetho ethile ethile yokwelashwa kwe-insulin.
Sebenzisa ebudaleni
Ezigulini esezikhulile, umthamo womuthi kufanele ulungiswe.
Isabelo sezingane
Umthamo we-insulin ubekelwe ingane ngayinye ngokuya ngezinkomba zeglucose yegazi, kucatshangelwa izidingo zomzimba wayo.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Ngenxa yokuthi i-insulin ayidluleli kwi-placenta, akukho okubangisana nemikhawulo yokusetshenziswa kwayo ngabesifazane abakhulelwe.
Ngaphambi kokukhulelwa okungenzeka futhi kukho konke kufanele kubhekelwe isimo sempilo yowesifazane otholakala ukuthi unesifo sikashukela, kubandakanya nokuqapha ushukela egazini.
Isidingo sowesifazane okhulelwe se-insulin sincipha ku-1st trimester, nakuma-2nd kanye no-3, ama-hormone kufanele ukuthi aqalwe. Ngesikhathi sokudlula kwabasebenzi futhi ngokushesha emva kwabo, isidingo sowesifazane okhulelwe se-insulin singancipha ngokuzumayo. Ngemuva kokubeletha, umzimba womuntu wesifazane ngaleli hormone uyefana njengoba wawunjalo ngaphambi kokukhulelwa. Ngesikhathi sokuncelisa, i-insulin isetshenziswa ngaphandle kwemikhawulo (i-insulin kamama oncelisayo ayilimazi ingane). Kodwa kwesinye isikhathi ukulungiswa komthamo kuyadingeka.
Umuthi awudluleli ubisi lwebele.
Isicelo sokusebenza kokulimala kwezinso
Ezimweni zomsebenzi okhubazekile walezi zitho, kungavela i-insulin ngokweqile. Njengoba ichitheka ezinso, ngokusebenza kwayo, ayinakukwazi ukufaka insulin. Ihlala egazini isikhathi eside, kanti amaseli amunca kakhulu ushukela. Ngakho-ke, ukulungiswa komthamo kuyadingeka.
Sebenzisa umsebenzi wesibindi okhubazekile
Njengezinso, isibindi sibhubhisa i-insulin. Ngakho-ke, ngokungasebenzi kwayo, ukulungiswa komthamo kuyadingeka.
Ukweqisa kwe-Insugen P
Izimpawu zokweqisa ngokweqile yimiphumela ye-hypoglycemia (ukujuluka ngokweqile, ukukhathazeka, ukukhathazeka kwesikhumba, ukwethuka noma injabulo ngokweqile yezinzwa, umuzwa wokukhathala noma ubuthakathaka, isiyezi, ukuncipha kokuxineka, umuzwa okhulayo wendlala, isicanucanu, kanye nesilinganiso senhliziyo esikhulayo).
Ukwelashwa ngokweqile: isiguli singabhekana ne-Hypoglycemia encane ngokudla okuthile okunokuqukethwe kwe-glucose: ushukela noma okunye ukudla okuphezulu kuma-carbohydrate (kunconyelwa ukuba njalo noshukela noma amanye amaswidi nawe). Kwi-hypoglycemia ebukhali, lapho isiguli siphelelwa amandla, isisombululo se-40% dextrose ne-glucagon ye-hormone (0.5-1 mg) sifakwa emthanjeni. Ngemuva kokuthi isiguli siphinde siqaphele ukuze i-hypoglycemia ingaphinde yenzeke, kunconywa ukuthi idle ukudla okune-carb ephezulu.
Ukuxhumana nezinye izidakamizwa
I-Fenfluramine, i-cyclophosphamide, i-clofibrate, ama-mao inhibitors, ama-tetracyclines, amalungiselelo we-anabolic steroid, ama-sulfonamides, ama-beta-blockers angakhethi, aqukethe i-ethyl alcohol, aholela ekwandeni komphumela we-hypoglycemic (umphumela wokwehlisa ushukela) we-insulin.
I-Thiazide diuretics, i-heparin, ama-antidepressants ama-tricyclic, amalungiselelo we-lithium, ama-hormone e-thyroid, ama-glucocorticoids, izindlela zokuvimbela inzalo zomlomo ziholela ekwenzeni buthaka umphumela we-hypoglycemic.
Ngokusetshenziswa okuhlangene kwama-salicylates noma i-reserpine ene-insulin, umphumela wawo ungakhuphuka futhi unciphe.
Ama-Analog
Okufanayo esenzweni izidakamizwa ezifana
- I-Actrapid NM;
- I-Protafan NM;
- Yeqa;
- Humulin Njalo.
Ukuhambisana notshwala
I-ethyl alcohol kanye nenqwaba yama-disinfectants aqukethe kungaholela ekwandeni kwe-insulin.
Imibandela yekhefu lekhemisi
Ithuluzi lingathengwa kuphela ngokubhaliwe.
Ngingakwazi ukuthenga ngaphandle kadokotela
Lesi sidakamizwa sehomoni, ngakho-ke asisatshalaliswa ngaphandle kokuthola umuthi.
Intengo ye-Insugen R
Izindleko ziyahlukahluka phakathi kwama-ruble angama-211-1105. Kusuka ku-7 kuye ku-601 UAH. - e-Ukraine.
Izimo zokugcina zomuthi
Umkhiqizo kufanele ugcinwe emazingeni okushisa we- + 2 ... + 8 ° C, kugwema ukuqandelwa iqhwa. Izingane akufanele zithole umuthi.
Umkhiqizo kufanele ugcinwe emazingeni okushisa we- + 2 ... + 8 ° C, kugwema ukuqandelwa iqhwa. Izingane akufanele zithole umuthi.
Isikhathi sokuphelelwa yisikhathi
Impilo yeshelf iyinyanga ezingama-24.
Umuthi kufanele usetshenziswe emavikini ayisithupha ngemuva kokuqala kokusetshenziswa kwebhodlela lapho ligcinwa endaweni yokushisa engeqi ku + 25 ° C.
Uma usuku lokuphelelwa isikhathi oluboniswe kwiphakheji lidlulisiwe, umuthi wenqatshelwe ukusebenzisa. Uma ngemuva kokuhlikihla isixazululo ku-vial kuba ngamafu noma kukhona ukungcola okukhona, umuthi uvinjelwe.
Umkhiqizi
Biocon Limited, India.
Ukubuyekezwa mayelana ne-Insugen R
UVenus, oneminyaka engama-32 ubudala, iLipetsk
Odokotela banquma amaphilisi kagogo amatafula aphezulu kashukela, futhi umalume uhlala ezinikeza imijovo ebekwe udokotela. Omunye wale mijovo yi-Insugen.
Lokhu kusho ukuthi umalume uzigwaza amahlandla ama-4 ngosuku, ngokulandelana, isenzo asihlali isikhathi eside. Kepha uyawuncoma umuthi. Ngaphezu kwalokho, uthatha ezinye izinhlobo eziningi zezidakamizwa.
Umphumela wesidakamizwa muhle, kepha badinga ukwelashwa kuphela ngemuva kokubonisana nochwepheshe noxilongo.
U-Elizabeth, oneminyaka engama-28, uBryansk
Ugogo wami ube nesifo sikashukela iminyaka eminingi. Ngo-2004, wanikezwa insulin. Uzame izidakamizwa eziningi ezahlukene. Odokotela sebekhathele ukukhetha okuyiyona. Ngemuva kwalokho balanda i-Insugen.
Imithamo edingekayo ngayinye ineyabo. Ugogo wakhetha umthamo kadokotela. Sidinga lo muthi. Ngincoma lesi sidakamizwa kuwo wonke umuntu, kithina uhlobo olufanele kunazo zonke lwe-insulin. Kepha kungcono ukubonana nochwepheshe kuqala. Leli yithuluzi elinamandla kangangokuthi ngaphandle kokugadwa udokotela kufanele ungaqali ukwelashwa ngokwakho.
U-Olga, oneminyaka engama-56, Yekaterinburg
Umuthi omuhle, ofanele ukugxuma okuqinile nokubukhali kushukela wegazi. Umuthi usebenza imizuzu engama-30 ngemuva kokuba umjovo wenziwe. Umphumela wazo uhlala cishe amahora angama-8. Odokotela bathi lolu hlobo olufanele kunazo zonke lwe-insulin. Kepha kungaba ngcono kakhulu uma kungafanele ukuthi kukhishwe, kepha kuthathwe ezibhebheni.
UTimofey, oneminyaka engama-56, uSaratov
Sengibe nesifo sikashukela cishe iminyaka engamashumi amathathu. Ngisebenzisa inani elifanayo le-insulin. Ekuqaleni, wamjova uHumulin R nezinye izifaniso. Kodwa-ke, wazizwa engathandeki. Noma kubhekwa ukuthi ushukela bekuyinto ejwayelekile.
Okusanda kuzanywa i-Insugen. Ngiyisebenzisa izinsuku eziningana, ngabona ukuthi impilo yami ibingcono kakhulu. Umuzwa wokukhathala nokudangala wanyamalala.
Angigcizeleli nanganoma iyiphi indlela, kodwa ngicabanga ukuthi lesi sidakamizwa siyikhwalithi ephezulu kakhulu.
