I-Glurenorm isetshenziswa kaningi ezimweni lapho ukudla kungahambelani khona nokulungiswa kwe-glycemia. Le pathology yenzeka ku-90% yeziguli ezinesifo sikashukela, futhi idatha ye-static ikhombisa ukuthi inani leziguli ezinjalo liyanda.
Igama Lezwe elingafanele
Glycidone. (NgesiLatin - Gliquidone).
I-Glurenorm isetshenziswa kaningi ezimweni lapho ukudla kungahambelani khona nokulungiswa kwe-glycemia.
I-ATX
A10BB08.
Khipha amafomu nokwakheka
Amathebhulethi ayindilinga anendawo ebushelelezi engu-30 mg ye-glycidone, okuyisakhi esiyinhloko esisebenzayo sezidakamizwa.
Ezinye izinto:
- isitashi esinganyibiliki nesomisiwe esitholakala kummbila;
- i-monohydrogenated lactose;
- i-magnesium stearate.
Isenzo se-Pharmacological
I-Glycvidone ibonakala ngomphumela we-pancreatic / pancreatic. Umuthi uthuthukisa ukukhiqizwa kwe-insulin ngokunciphisa umphumela we-glucose kumaseli we-pancreatic beta. Ngaphezu kwalokho, umuthi ukwandisa ukutholakala kwe-insulin nokuxhuma kwawo namaseli okuhlosiwe, kwandisa umphumela wawo ukufakwa kwe-glucose yizakhi zesibindi nemicu yemisipha, futhi kwehlise izinqubo ze-lipolytic kuma-tishu e-adipose.
Inomsebenzi we-hypolipidemic, wehlisa izici ze-thrombogenic ze-plasma yegazi. Umphumela we-hypoglycemic utholakala ngemuva kwamahora angu-1-1,5.
Umuthi uthuthukisa ukukhiqizwa kwe-insulin ngokunciphisa umphumela we-glucose kumaseli we-pancreatic beta.
I-Pharmacokinetics
Into esebenzayo icishe icwenge ngokuphelele izindonga zesisu. I-Cmax yesithako ifakwa kumahora ayi-2-3. I-Glycvidone metabolism yenziwa isibindi. Ukuqedwa kwesigamu sempilo cishe imizuzu engama-80. Ama-metabolites amaningi akhishwa emzimbeni ngamathumbu kanye ne-bile. Izinso zibiza cishe u-10% wesidakamizwa.
Izinkomba zokusetshenziswa
Umyalo uthi i-MP ihloselwe ukwelashwa kwe-Type 2 sikashukela mellitus, uma ukwelashwa kokudla kunganikeli imiphumela emihle.
Contraindication
- ukuvuselelwa emuva kokuqalwa kabusha kwamanyikwe;
- hypersensitivity to sulfonamides, sulfonylurea kanye ne-coumarin derivatives;
- isifo sikashukela / ukukhohlisa kwesifo sikashukela, i-ketoacidosis;
- thayipha i-1 isifo sikashukela;
Ngokunakekela
- uphuzo oludakayo;
- ukulimala kwezinso nesibindi;
- ukwanda kwezifo ze-yegilo.
Ungayithatha kanjani i-glurenorm
Ngaphakathi, ngokuya ngemiyalo kadokotela maqondana nemithamo, isikhathi sokwelashwa kanye nokubambelela ekudleni okukhethiwe.
Ekuqaleni kokwelashwa, kuthathwa imithamo yamathebulethi ayi-0,5 ngesikhathi sokudla kwasekuseni. Uma kungekho ngcono, umthamo uyandiswa kancane kancane.
Uma umthamo wansuku zonke udlula amaphilisi ama-2, khona-ke kufanele uhlukaniswe ngamaphilisi ama-2-3, kepha kuyelulekwa ukuthatha ingxenye enkulu yomuthi ekuseni. Ngosuku olungu-1 kwenqatshelwe ukuthatha amaphilisi angaphezu kwama-4.
Uma kungekho isenzo ngesikhathi se-monotherapy nomuthi, ukwelashwa okuhlangene kunqunywa kanye ne-metformin.
Ngoshukela
Abantu abanesifo sikashukela kufanele balandele imiyalo kadokotela, ngaphandle kwalokho kungenzeka banciphise izinga le-glucose ye-plasma kuze kube yilapho belahlekelwa ukwazi.
Isifo sikashukela kufanele silandele imiyalo kadokotela.
Imiphumela emibi Glyurenorma
- metabolism: hypoglycemia;
- izicubu ezithambile nezikhumba: i-photosensitivity, ukuqubuka, ukuvuvukala;
- Umbono: izinkinga ngendawo yokuhlala;
- Ipheshana lesisu: ukungakhululeki emgodini wesisu, i-cholestasis, ukugabha, isifo sohudo, ukuqunjelwa, ukulahleka kwesifiso sokudla;
- I-CVS: i-hypotension, ukungakwaneli kwemithambo yegazi nenhliziyo, i-angina pectoris, extrasystole;
- I-CNS: i-vertigo, ukukhathala, i-migraine, i-lethargy;
- uhlelo lwe-hematopoietic: i-agranulocytosis, i-leukopenia.
Umthelela ekhonweni lokulawula izindlela
Iziguli ezithola i-MP kufanele zaziswe ngobungozi besiyezi nesihlungu sekhanda ngalesi sikhathi. Ngakho-ke, kufanele baphaphame lapho beshayela imoto futhi benza umsebenzi wokugxilisa ingqondo.
Iziguli ezithola i-MP kufanele zaziswe ngobungozi besiyezi nesihlungu sekhanda ngalesi sikhathi.
Imiyalo ekhethekile
Izidakamizwa ze-Oral hypoglycemic aziyona indawo yokudla ezisiza ukuqapha isisindo somzimba.
Uma uphuza amaphilisi ngaphambi kokudla, ingozi ye-hypoglycemia iyanda. Uma kunezimpawu, khona-ke kufanele udle ngokushesha uswidi noma omunye umkhiqizo, oqukethe ushukela.
Ukuzivocavoca umzimba kungakhulisa umsebenzi we-hypoglycemic we-MP.
Sebenzisa ebudaleni
Izici ze-pharmacokinetic zomuthi ezigulini esezikhulile azishintshi.
Ukunquma iGlenrenorm ezinganeni
Ezinganeni ezingaphansi kweminyaka engu-18 ubudala kufakwa umthetho wokuthi zivunyelwe.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Akunalo ulwazi mayelana nokusetshenziswa kwe-glycidone kwabesifazane abakhulelwe / abakhipha i-lactating, ngakho-ke i-MP ayisetshenziswa ngalesi sikhathi.
Ehlelweni lokuhlela ukukhulelwa, kungakuhle ukuthi ukhansele umuthi futhi usebenzise i-insulin ukulungisa ushukela.
Kungama-5% kuphela we-MP adalulwa ezinso, ngakho-ke akukho okuphambene nalokho kulokhu.
Isicelo sokusebenza kokulimala kwezinso
Kungama-5% kuphela we-MP adalulwa ezinso, ngakho-ke akukho okuphambene nalokho kulokhu.
Sebenzisa umsebenzi wesibindi okhubazekile
Ezimweni ezinamandla zokuhluleka kwesibindi ne-porphyria, umuthi awusetshenziswa. Lokhu kungenxa yokuthi iningi le-MP liyahlukana kulesi sitho.
I-Glenormorm overdose
Umphumela onokwenzeka kakhulu yi-hypoglycemia, engahle ihambisane nokujuluka ngokweqile, i-tachycardia, ikhanda, ukulala, ukuphazamiseka kombono nokukhuluma, ukulahleka kwengqondo nokukhubazeka kwezimoto.
Ukuqeda izimpawu ezingezinhle, kunconywa ukubiza i-ambulensi futhi udle i-dextrose noma ukudla okuqukethe ama-carbohydrate amaningi. Ezimweni ezimbi kakhulu, i-dextrose ilawulwa ngaphakathi. Ngezinhloso zokuvimbela, kukhonjiswa ama-carbohydrate angaphakathi.
Ukujuluka okwandayo kungenye yezimpawu zokusetshenziswa ngokweqile komuthi.
Ukuxhumana nezinye izidakamizwa
Ama-Sympatholytic agents, i-guanethidine, i-reserpine ne-beta-blockers, ama-cyclophosphamide nama-hormone egilo akhulisa umphumela we-hypoglycemic womuthi futhi afihle nezimpawu ze-hypoglycemia.
I-Phenytoin, i-rifampicin ne-barbiturates yehlisa izindawo ze-hypoglycemic glycidone.
Ukuhambisana notshwala
Akunconywa ukuhlanganisa.
Ama-Analog
- I-Glibetic;
- IGlairie
- Lungisa;
- IGlllada;
- Glianov.
IGliclada ingelinye lamagama afanayo.
Imibandela yekhefu lekhemisi
Ngingakwazi ukuthenga ngaphandle kadokotela
Kumakhemisi, kunqunywa amaphilisi.
Intengo Glyurenorm
Ebangeni lama-ruble angama-379-580. iphakethe ngalinye lama-60 ama-PC.
Izimo zokugcina zomuthi
Izimo ezifanele: izinga lokushisa lamakamelo, umswakama olinganiselayo, ukuntuleka kokukhanya.
Isikhathi sokuphelelwa yisikhathi
Ayidluli iminyaka emi-5.
Umkhiqizi
Inkampani yamaGrikhi "Boehringer Ingelheim Ellas".
Ukubuyekezwa mayelana neGlyurenorm
Odokotela
UDarina Bezrukova (owelaphi), oneminyaka engama-38 ubudala, i-Arkhangelsk
Lesi sidakamizwa sinqunyelwe ngokuhambisana nokwelapha uhlobo lwe-2 yesifo sikashukela. Kulokhu, isiguli kufanele sinamathele ekudleni okukhethekile. Ushukela ulawula ngokuqinile nangendlela efanele.
U-Andrey Tyurin (owelaphi), oneminyaka engama-43 ubudala, eMoscow
Ngibhalela isifo sikashukela. Amaphilisi awabizi kakhulu, athuthukisa isimo sawo ngokushesha. Ngasikhathi sinye, akunqweneleki ukuthi abesifazane abakhulelwe basebenzise umuthi. Ngibanikeza imijovo ye-insulin.
Kumakhemisi, kunqunywa amaphilisi.
Isifo sikashukela
UValeria Starozhilova, oneminyaka engama-41, uVladimir
Ngiyagula nginesifo sikashukela, lo muthi utholwa mahhala. Udokotela ungene endaweni kaDiabeteson, engaqala ukungezwani nayo. Kubonwa inyanga. Ushukela ugcinwa ngezinga elijwayelekile, kepha ukusabela okubi kusangifikele. Kwabonakala umlomo owomile ongabekezeleleki, ubuthongo baphazamiseka, nekhanda laqala ukuzizwa linesiyezi. Wabe esengena ezinkingeni zokugaya. Izimpawu ezingezinhle zanyamalala ngemuva kwamasonto ayi-1.5 ngemuva kokuqala kokuthatha amaphilisi. Izinkomba zibuyele kokujwayelekile, isimo sathuthuka.
U-Alexey Barinov, oneminyaka engama-38, eMoscow
Ngiseyinsizwa, angikaze ngidle ukudla okulinganiselayo futhi ngisebenzise kabi utshwala. Manje ngiyavuma ukuthi isifo sikashukela saziphazamisa. Ngazama ukwelashwa ngezindlela ezahlukahlukene. Muva nje, udokotela ubeke la maphilisi. Ukuhlaselwa ekuqaleni kwaqala ukuvela kancane, kwathi ngemuva kwamasonto angama-2-2,5 emva kokuphathwa, anyamalala ngokuphelele. Iphupho libuyele kwelejwayelekile, imizwa yavuka, umjuluko wanyamalala. Udokotela wathi izinkomba zami zokwelashwa sezithuthukile. Umuthi uyasebenza!
