I-Finlepsin 400 retard ingumuthi ofakazelwe wentengo elinganiselayo osetshenziswa ekwelapheni ukubanjwa kokuqunjelwa, isifo sokuphazamiseka kwengqondo, isimo sokudangala kanye neuralgia.
Igama Lezwe elingafanele
Carbamazepine
Ukubuyiswa kwe-Finlepsin 400 kungumuthi ofakazelwe wentengo elinganiselayo osetshenziswa ekwelapheni ukubanjwa kokuqunjelwa, isifo sokuphazamiseka kwengqondo, isimo sokudangala kanye neuralgia.
Ath
I-N03AF01 Carbamazepine
Khipha amafomu nokwakheka
Kutholakala ngohlobo lwamaphilisi ayindilinga anemibala emhlophe noma amaphilisi okusebenza isikhathi eside egobolondweni.
Kwiphakheji elilodwa lamakhadibhodi ama-5 oswidi anamaphilisi ayi-10.
Kuqukethe into esetshenziswayo (i-carbamazepine) ngesilinganiso sama-400 mg, futhi kufaka phakathi ukubopha okwengeziwe, ukuncibilikisa nezinye izinto ezifanayo.
Kusebenza kanjani
Umphumela wemithi yesidakamizwa ukuqinisa ukuqina kwama-neurons ngokuvimba ama-calcium tubules. Lo mphumela uholela ekuqhubekeni okuphansi kwama-synapses we-neuron, kuyilapho kwakhiwa i-serial disc.
Umuthi ngukuphathisa anticonvulsant, antidiuretic, analgesic, ukuzinza kwemizwa kanye nomphumela we-diuresis-lowering.
I-Pharmacokinetics
Ukuphuza umuthi kuhamba kancane, kepha kucishe kuphelele. Cishe i-80% yento esebenzayo ebopha amaprotheni e-plasma, okusele kungashintshiwe. Idlulela ubisi lwebele futhi idlule kwi-placenta iye e-fetus.
Amazinga wegazi aphezulu kakhulu - amahora ambalwa ngemuva kokungena. Lapho usebenzisa amaphilisi anezinyathelo ezenzeka isikhathi eside, ukugxila kuphansi. Ibhalansi yokuhlushwa ifinyelelwa ngemuva kwezinsuku ezi-2-8 zokuphuza umuthi.
Ukungezelela umthamo ngaphezulu kokunconyiwe akunikezi umphumela omuhle futhi kuholela ekwandeni kwesimo.
Kukhishwa ikakhulu izinso ngesimo se-metabolite, kepha ingxenye yawo iyasuswa emzimbeni ngamalongwe futhi inani elithile aliguquki.
Okusizayo
Ithuluzi liyasebenza ekwelapheni kwale mibandela elandelayo:
- i-syndromes yesithuthwane ne-epileptic (isusa ukubonakaliswa koshintsho lobuntu ezigulini ezinesifo sokuwa, kunciphisa ukukhathazeka, ukungabinakho nolaka, kunomthelela wokuphikisana);
- isimo sokuhoxa (kunciphisa ubulukhuni bokuqhaqhazeka nokuxineka kwe-gait, kunciphisa ukukhathazeka, kukhulisa umkhawulo wokulungela ukweyisa);
- ukuphazamiseka kokulala;
- i-neuralgia: i-postherpetic, i-neongia yamuva ne-post-traumatic neuralgia, izilonda ze-glossopharyngeal nerve (isebenza njenge-analgesic);
- i-sclerosis eminingi;
- i-paresthesia yesikhumba;
- Izimo ezi-manic acute, i-affidal ye-bipolar, ukukhathazeka, ukuphazamiseka kwengqondo, ukucabanga ngemvelaphi yemvelo (isenzo ngokunciphisa ukukhiqizwa kwe-dopamine ne-norepinephrine)
- isifo sikashukela i-polyneuropathy, isifo sikashukela i-insipidus (ikhulula izinhlungu, sinxephezela ukulinganisela kwamanzi, sinciphise i-diuresis nokoma).
Ukusebenza kwesidakamizwa esithile kufanele kubhekwe maqondana nokuthathwa kokuwaxhuzula kanye neuralgia ye-trigeminal.
Kusetshenziswa zombili ngesimo se-monotherapy, futhi njengengxenye yezidakamizwa eziyinkimbinkimbi (ezimweni ezibandayo ze-manic, ukuphazamiseka kokuphefumula, njll.).
Contraindication
I-Finlepsin ayinqunyelwe emacaleni alandelayo:
- hypersensitivity kwento esebenzayo noma izinto ezifanayo ekwakhekeni kwamakhemikhali;
- nge-atrioventricular block;
- nge-hepatic porphyria;
- nokucindezelwa komongo.
Kwesinye isikhathi kuyabekelwa, kepha ngaphansi kokuqashwa njalo kukadokotela, esigulini esinomlando we-hypersecretion ye-antidiuretic hormone syndrome, sehlile ukukhiqizwa kwama-pituitary noma ama-thyroid, ama-hormone e-adrenal cortex, ngokucindezela okungaphezulu kwe-intraocular.
Isetshenziswe ngokucophelela i-alcoholic esigabeni esisebenzayo nasebekhulile.
Ungayithatha kanjani i-Finlepsin 400
I-Finlepsin ihanjiswa ngomlomo ngamanzi amaningi. Umthamo wansuku zonke akufanele udlule ku-1600 mg. Izingane nezinye iziguli ezinenkinga yokuphuza amaphilisi zingaqeda umuthi emanzini noma ujusi.
Njenge-antiepileptic, kuthathwa ngokuya ngohlelo olulandelayo:
- Abantu abadala nezingane ezingaphansi kweminyaka engu-15 yobudala ziqala ukwelashwa nge-200-400 mg, zanda kuze kube yilapho umphumela utholwa, kepha ungeqi isilinganiso esikhulu sansuku zonke. Ukwelashwa okuqhubekayo kuqukethe ekunqumeni kusuka ku-800 kuya ku-1200 mg wesidakamizwa ku-1 noma i-2 doses.
- Ezinganeni ezisukela eminyakeni eyisithupha, i-dosing iqala ngo-200 mg bese ikhuphuka kancane kancane nge-100 mg ngosuku kuze kube yilapho umphumela olindelekile utholakala. Ukwelashwa kwesondlo izikhathi ezi-2 ngosuku: kusuka eminyakeni engu-6 kuye kweyi-10 - 400-600 mg, kusuka eminyakeni engu-11 kuye kwengu-15 - u-600-1000 mg.
- Eminyakeni engu-6, lo muthi awuchaziwe.
Isikhathi sokwelashwa, kanye nokwehla noma ukwanda komthamo, sinqunywa ngudokotela.
Umuthi uyakhanselwa uma kungakapheli iminyaka eyi-2-3 kube kungekho ukuhlaselwa.
Nge-neuralgia (i-trigeminal, postherpetic, post-traumatic) kanye nezilonda ze-glossopharyngeal nerve, umthamo wokuqala wama-200 mg ngosuku ubekiwe ngokunyuka kancane kancane kuze kufike ku-800 mg ngosuku. Umthamo wokulondolozwa ungama-400 mg ngosuku, ngaphandle kwabadala nasezigulini ezinomlando we-hypersensitivity kwento esebenzayo (200 mg ngosuku).
Kwi-conculsive syndrome ezigulini ezine-sclerosis eminingi, umthamo wansuku zonke uqala kusuka kuma-200 mg ngokukhuphuka kuye ku-400 mg.
Ngokuhoxiswa kotshwala, ukwelashwa ngezidakamizwa kwenziwa kuphela esibhedlela kuhlangene nezinye izindlela. Umthamo - kusuka ku-600 kuya ku-1200 mg ngosuku ngethamo eliphindwe kabili.
I-Finlepsin ihanjiswa ngomlomo ngamanzi amaningi.
Ekwelashweni kwe-psychosis, isetshenziswa kumthamo ka-200 kuya ku-400 mg ngosuku ngokunyuka okungenzeka kube ngama-600 mg (ukuphazamiseka kwengqondo kanye nokuphazamiseka okubambekayo).
Nge-neuropathy yesifo sikashukela
Ukuze uthole izinhlungu, umthamo wansuku zonke unqunywe ekuseni - 200 mg, kusihlwa - 400 mg. Ukufeza umphumela omuhle, umthamo wansuku zonke ungangezelelwa ufike ku-600 mg. Ezimweni ze-manic zinika i-1600 mg ngosuku.
Kuthatha isikhathi esingakanani
Ukuqina kuvame ukudlula ngemuva kwamahora ambalwa futhi kuyeke ngokuphelele ezinsukwini ezimbalwa. Umphumela we-antipsychotic ubonakaliswa kakhulu ezinsukwini ezingama-7-10 ngemuva kokuqala kokuphatha.
Umphumela we-anesthetic utholakala ngemuva kwamahora we-8-72.
Khansela
Isheduli yokuhoxiswa kwezidakamizwa isayinwa ngudokotela obonayo futhi yenziwa kungakapheli iminyaka eyi-2-3 ngemuva kokuqala kokusetshenziswa. Umthamo uncishiswa kancane kancane ngaphezulu kweminyaka eyi-1-2 ngokuqapha okungapheli kwe-echoencephalogram.
Ngasikhathi sinye, izingane zinqunywa uhlelo lokukhanselwa, uma lunikezwa ushintsho kwesisindo somzimba ngokukhula.
Imiphumela emibi yeFinlepsin 400
Imiphumela emibi eyinhloko ibonakaliswa ekuphazamisweni kohlelo lwezinzwa oluphambili (isiyezi, ukozela, ukulahlekelwa umuzwa wangempela, ubunzima bokukhuluma, i-paresthesia, ukungabi namandla), i-psyche (ulaka, ukudangala, umbono), uhlelo lwe-musculoskeletal (izinhlungu ezihlangene, izinhlungu zemisipha kanye namaqhubu), izitho zomzimba imizwa (i-tinnitus, ukwenza buthaka ukunambitheka, ukuvuvukala kwe-conjunctiva), isikhumba (i-pigmentation, induna, i-Arrura, i-baldness), uhlelo lokuphefumula (i-pulmonary edema) kanye ne-allergies.
Amapheshana wesisu
Imiphumela emibi evela emgodini wesisu ivezwa isicanucanu, ukugabha, ukuphazamiseka kwesitulo, ipancreatitis, i-stomatitis ne-glossalgia.
Izitho zeHematopoietic
Ukuthatha umuthi kungakhuphula inani lamapuleti, ama-eosinophils, izinhlobo ezahlukahlukene ze-anemia, i- "intermittent" porphyria.
Kusuka ohlelweni lomchamo
Kwesinye isikhathi kuba khona i-oliguria kanye nokugcinwa komchamo.
Kusuka ohlelweni lwezinhliziyo
Ukuguquguquka okungenzeka kumfutho wegazi, ukuncipha kwenhliziyo, ukukhuphula kwesifo senhliziyo.
Kusuka ohlelweni lwe-endocrine kanye nemetabolism
Uhlelo lwe-endocrine kanye nemetabolism zingaphendula lesi sidakamizwa ngokuncipha kokuhlushwa kwe-L-thyroxine kanye nokwenyuka kwe-TSH, ukukhuphuka kwesisindo somzimba, kanye ne-cholesterol level.
Allergies
Ngokuvamile, ama-allergis aboniswa yi-urticaria, vasculitis, ukuqubuka kwesikhumba. Kwesinye isikhathi kungenzeka: i-angioedema, i-allergic pneumonitis, i-photosensitivity.
Umthelela ekhonweni lokulawula izindlela
Ngesikhathi sokuthatha i-Finlepsin, kuyadingeka ukwenqaba ukushayela imoto nokuxhumana ngokucophelela ngezinqubo eziyinkimbinkimbi, umsebenzi odinga isivinini sokuphendula kwe-psychomotor.
Imiyalo ekhethekile
Ukusetshenziswa kwalesi sidakamizwa kufanele kunqunyelwe kuphela ngaphansi kokuqashwa kwezokwelapha ngemuva kokuhlola inani lezinzuzo ezingcupheni ezingaba khona. Njengesimo - ukuqapha ngokucophelela iziguli ezinesifo senhliziyo, ukuphazamiseka kwesibindi noma izinso, ukusabela komzimba ngaphambili.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Kulokhu, i-reception ayinconywa. Uhlelo lokusebenza luvunyelwe ngemuva kokuqhathanisa izinkomba ezibalulekile nezingozi zengane kanye nosana olusanda kuzalwa. Abesifazane abathole ukwelashwa kwe-Finlepsin ngesikhathi sokukhulelwa bavame ukuzwa ukukhubazeka kwengane.
Sebenzisa ebudaleni
Iziguli esezikhulile zinqunywe kumthamo oncishisiwe futhi kungenzeka nemiphumela emibi ngendlela yokudideka iyabhekwa.
Ukuphathwa kwe-Finlepsin ezinganeni ezingama-400
Ukuqokwa kuvunyelwe kusukela eminyakeni eyisithupha.
Isicelo sokusebenza kokulimala kwezinso
Ukwamukela ngokuqapha.
Sebenzisa umsebenzi wesibindi okhubazekile
Kunqunywa ngokuqapha ngaphansi kokuqondisa kochwepheshe bezokwelapha nangokubheka izinkomba zomsebenzi wesibindi.
I-Overdose ye-Finlepsin 400
Uma uthatha umuthi omningi kakhulu, imvamisa kungahle kube nokwanda kwemiphumela emibi evela ohlelweni lwezinzwa oluphakathi (ukuvimbela ukusebenza, ukudideka, ukukhishwa kwethoni, ushintsho kuma-psychomotor indices), amasistimu wezinhliziyo (ukukhuphuka kwenhliziyo, ukuncipha kwegazi, ukuboshwa kwenhliziyo), ipheshana lesisu (isicanucanu) , ukuhlanza, ukungahambi kahle kwamathumbu amathumbu).
Ukuqeda imiphumela yokweqisa, ukufakwa kwesibhedlela esikhungweni sezokwelapha kuyenziwa, ukuhlaziya okusheshayo ukuthola inani lezinto egazini, ukugcwala kwesisu, kanye nokuqokwa komuntu ololayo.
Esikhathini esizayo, ukwelashwa okubonakalayo kuyenziwa.
Ukuxhumana nezinye izidakamizwa
Sebenzisa ukuqaphela uma kunesidingo sokuhlanganisa umuthi nezinye izinto.
Inhlanganisela ayinconywa
Ngokusetshenziswa ngasikhathi sinye, kwandisa umphumela onobuthi weparacetamol, izidakamizwa ze-anesthesia jikelele, isoniazid,
Ama-inhibitors ama-MAO akhulisa ingozi yokuthola izingxabano ezinamandla amakhulu, ukubanjwa kokushona nokufa.
Ngokunakekela
Kunganciphisa ukusebenza kwezindlela zokuvimbela inzalo ngomlomo, i-cyclosporine, i-doxycycline, i-haloperidol, i-theophylline, i-tricyclic antidepressants, dihydropyridones, proteinase inhibitors yokwelapha i-HIV.
Ukuhambisana notshwala
Ayihambisani notshwala.
Ama-Analog
IZagretol, Zeptol, Carbamazepine, Karbalin, Stazepin, Tegretol.
Imibandela yekhefu lekhemisi
Kuthengiswa ngokukhethekile ngomuthi.
Ngingakwazi ukuthenga ngaphandle kadokotela
Akukho okubhalwe phansi akusatshalwanga.
I-Finlepsin 400 Intengo
Intengo isukela kuma-ruble ayi-130 kuye kwangama-350. kuya ngomkhiqizi nendawo okuthengiswa kuyo.
Izimo zokugcina zomuthi
Gcina endaweni yokushisa engeqi ku-30 ° C lapho izingane zingafinyeleleki khona.
Gcina endaweni yokushisa engeqi ku-30 ° C lapho izingane zingafinyeleleki khona.
Isikhathi sokuphelelwa yisikhathi
Akukapheli iminyaka engu-3 kusuka ngosuku lokukhiqizwa. Ungasebenzisi ngemuva kokuphela kosuku.
Umkhiqizi
Ikhiqizwa yizinkampani ezahlukahlukene zemithi eJalimane nasePoland:
- Menarini-Von Hayden GmbH.
- IPliva Krakow, A.O. Isitshalo Sezitshalo
- Imisebenzi ye-Teva Poland Sp. z o.o.
Ukubuyekezwa kodokotela neziguli mayelana neFinlepsin 400
U-Anna Ivanovna, udokotela wezifo zemizwa, u-Omsk
Imvamisa, ekusebenzeni kwe-neurologist, isetshenziswa njenge-anticonvulsant noma i-antidepressant. Lapho unquma, kuyadingeka ukutadisha ngokucophelela ama-anamnesis nazo zonke izinkomba, ngoba imiphumela emibi enamandla yenzeka. Ngiyincoma njengesidakamizwa esisebenzayo nesingabizi.
UNatya Nikolaevna, udokotela womndeni, uSaransk
Ngiyincoma njengekhambi elisebenzayo le-neuralgia ye-trigeminal, ukuphazamiseka kokukhathazeka, isithuthwane, ubuhlungu besifo sikashukela, kanye nasezimweni zesifo sokuqina kwemithambo yesifo sikashukela i-mellitus.
UPavel, oneminyaka engama-40 ubudala, u-Ivanovo
Sekuphele iminyaka engu-3 ngithatha lo muthi ngenxa yesifo sokuwa. Ngalesi sikhathi, ngaba nokuzola, ukulala kwami kwaba ngcono nokubamba kwami amandla kwaba. Okubi ukuthi kukhona isiyezi esinzima ngezikhathi ezithile.
USvetlana, oneminyaka engama-34, uRyazan
Ukhethwe ngudokotela wengqondo wokucindezelwa. Amaphilisi asizile, bengiwaphuza unyaka manje, kepha isisu sami siqale ukuba buhlungu futhi nekhanda lami liyaqhuma ngezikhathi ezithile. Udokotela akeluleki ukukhanselwa kuze kube manje.
ULyudmila, oneminyaka engama-51 ubudala, iLipetsk
Kwasiza nge-neuralgia ye-trigeminal ngokushesha futhi ngaphandle kwemiphumela emibi. Ngaphambi kwalapho, ngase ngizinze izinyanga eziyisithupha nginezibhebhe ezahlukahlukene, kepha akubanga khonaomphumela. Angikwazanga ukumelana nayo futhi ngaphendukela kudokotela wezinzwa. I-Finlepsin yanqunywa, futhi manje azikho izinkinga nge-trigeminal nerve.