Uma amalungiselelo weMetformin neDiabetes ayabhekwa, kuyadingeka ukuwaqhathanisa ekwakhekeni, indlela yokwenza, izinkomba kanye nokuphikisana. Lezi zimali zingokweqembu lezidakamizwa ze-hypoglycemic. Isetshenziselwa ukuvimbela kanye nokwelashwa kwezinkinga zesifo sikashukela.
Izici zeMetformin
Umkhiqizi - Ozone (Russia). Umsebenzi we-Hypoglycemic uboniswa yi-metformin hydrochloride. Umuthi ukhiqizwa ezibhebheni. Ku-1 pc iqukethe ama-500, 850 noma ama-1000 mg wezinto ezisebenzayo.
I-Metformin iyatholakala ngesimo sethebulethi.
Ukuqanjwa kubandakanya izakhi ezisizayo:
- Copovidone;
- i-polyvidone;
- i-microcrystalline cellulose;
- i-colloidal silicon dioxide (aerosil);
- i-magnesium stearate;
- I-Opadry II.
Iphakheji liqukethe amaphilisi angama-30 noma angama-60. Indlela yokusebenza yesidakamizwa isuselwa ekuvinjelweni kwenqubo yokukhiqiza ushukela esibindini.
Umuthi wehlisela ukuqina kokufakwa kweglucous yizitho zomzimba zamathumbu. Ngasikhathi sinye, ukusetshenziswa kwe-glucose okuphathelene nokushesha kuyasheshiswa, okunciphisa ukugxila kwayo ku-plasma. Futhi kwandisa ukuzwela kwe-insulin.
Ngaphezu kwalokho, iMetformin ineqhaza ekwandeni kokubekezelela i-glucose. Lokhu kungenxa yokubuyiselwa komzimba wayo we-metabolism kanye ne-digestibility. Ngaphezu kwalokho, umuthi awuthinti ukucasulwa kwe-insulin yi-pancreas. Kodwa-ke, ukwakheka kwegazi kwenziwa njengokujwayelekile. Kulokhu, i-metformin hydrochloride ithinta i-lipid metabolism, ngenxa yokuthi kukhona ukwehla kwezinga le-cholesterol ephelele, i-triglycerides, i-lipensrensins ephansi. Umuthi awuchaphazeli ama-lipoprotein aphezulu.
Ngenxa yezinqubo ezichaziwe, isisindo somzimba sehlisiwe. Umkhawulo omkhulu wokusebenza kwomuthi ufinyelelwa emahoreni ama-2 ngemuva kokuthatha umthamo wokuqala womuthi. Ukudla kusiza ekunciphiseni ukumuncwa kwe-metformin hydrochloride kusuka emathunjini, okusho ukuthi amazinga e-plasma glucose awanciphi ngokushesha okukhulu.
Omunye umsebenzi wesidakamizwa ukucindezela inqubo yokukhula kwezicubu, okwenzeka ngenxa yokuqhekeka okukhulu kweseli. Ngenxa yalokhu, ukwakheka kwezakhi zemisipha ebushelelezi bezindonga ze-vascular akuguquki. Ngenxa yalokho, ingozi yokuthola izifo zenhliziyo iyancishiswa.
Umuthi unesikali esincane. Kubekelwe ushukela wegazi ophakeme. Ithuluzi lisetshenziselwa ukunciphisa isisindo somzimba emafutheni. Kulokhu, iMetformin ikhonjiswa ukusetshenziswa ezigulini ezitholakala zinesifo sikashukela sohlobo 2. Ingasetjenziswa njengesilinganiso esikhulu sokwelapha ekwelapheni abantwana abavela eminyakeni eyi-10 abanesifo sikashukela. Ngaphezu kwalokho, umuthi ubekwe njengengxenye yokwelapha okuyinkimbinkimbi. Kusetshenziswa kanye ne-insulin. Contraindication:
- isikhathi sokukhulelwa nokuncelisa;
- hypersensitivity engxenyeni esebenzayo;
- i-hypoglycemia;
- izifo ezinzima zesibindi;
- ukudla okuqukethe okuqukethwe kwekhalori okuncishisiwe (ngaphansi kuka-kcal we-1000 ngosuku);
- ukusetshenziswa kanyekanye nezinto ezinama-iodine ezisetshenziswa ngesikhathi sokuhlolwa;
- ubuthi botshwala;
- i-hypoglycemia;
- coma, inqobo nje uma imbangela yalesi simo se-pathological isifo sikashukela;
- i-precoma;
- ukungasebenzi kwe-renal (isimo se-pathological esihambisana nokushintshwa kwezinga le-proteinuria);
- ukulimala okukhulu, ukungenelela kokuhlinzwa;
- izifo ezinomthelela ekuthuthukiseni izicubu ze-izicubu;
- i-lactic acidosis;
- ukwephulwa okukhulu kohlelo lwezinhliziyo;
- ukungasebenzi kahle kwe-adrenal.
Imiphumela emibi:
- uhlelo lokugaya luyaphazamiseka: isicanucanu, uhudo, izinhlungu esiswini ziyavela, isifiso sokudla siyancipha;
- kukhona ukunambitheka kwensimbi emlonyeni;
- ukungahambi kahle komzimba, kuvame ukubonakalisa i-erythema.
Ukwelashwa kwe-Metformin kudinga ukunakwa okwengeziwe kusuka kwabanesifo sikashukela, ngoba kunengozi yokwehla okukhulu kwamazinga kashukela we-plasma. Ukugwema ukuthuthukiswa kwezinkinga, ukubhekwa kwesilinganiso se-glycemic kwenziwa njalo.
Isici sikashukela
Umkhiqizi - uServer (eFrance). I-Gliclazide isebenza njengengxenye esebenzayo. Ukukhishwa ifomu - amaphilisi. Ukuqoqwa kwento esebenzayo ku-1 pc. ngu-60 mg.
Izingxenye ezisizayo ze:
- i-calcium hydrogen phosphate dihydrate;
- i-hypromellose 100 cP;
- I-hypromellose 4000 cp;
- i-magnesium stearate;
- maltodextrin;
- abicah dioxide colloidal i-anhydrous.
Umuthi uyatholakala emaphaketheni aqukethe amaphilisi angama-30 no-60. Indlela yokusebenza yesidakamizwa isuselwa ekunciphiseni kwe-glucose ye-plasma. Ngesikhathi esifanayo, ukukhiqizwa kwe-insulin kuyathuthukiswa. Into esebenzayo ekwakhiweni iyi-sulfanylurea. I-insulin iyanda ngenkathi uthatha izidakamizwa eziqukethe ushukela nalapho udla. Ngenxa yalokhu, amazinga kashukela egazi enza ngokwejwayelekile.
I-Diabeteson iyatholakala ngesimo sethebhulethi.
Ukuzwela kwethishu ekwandeni kwe-insulin. Kodwa-ke, izinga lokukhiqizwa koshukela esibindini liyancipha. Ngaphezu kwalokho, umuthi unomphumela esimweni semithambo yegazi. Ngenxa yokucindezelwa kokuhlanganiswa nokwenqatshelwa komsebenzi we-platelet, kuyehla ukwehla kwamandla e-thrombosis. Ngenxa yalokhu, i-microcirculation yegazi iyabuyiselwa, ubungozi bokuthola izifo zohlelo lwethambo luyancishiswa.
Ingxenye esebenzayo ekwakhiweni kweDiabetes iyazibonakalisa njenge-antioxidant. Ngenxa yalokho, okuqukethwe kwe-lipid peroxides esegazini kuyancipha ngesikhathi sokwelashwa. Kanye nalokhu, umsebenzi we-erythrocyte superoxide dismutase uyanda.
Inkomba yokusetshenziswa uhlobo 2 sikashukela. Ngasikhathi sinye, isifo sikashukela singasetshenziswa ukuvikela izinkinga zalesi simo se-pathological. Kubekiwe ukuze kwehliswe isisindo somzimba, uma ukudla kanye nokuzivocavoca komzimba kungabi nomphumela ofanele. Ngaphezu kwalokho, umenzeli okukhulunywa ngaye angasetshenziswa ukuvikela ukuthuthukiswa kwezifo zenhliziyo.
Contraindication:
- ukusabela okungekuhle komuntu ngamunye kunoma iyiphi ingxenye ekwakhiweni kwesifo sikashukela;
- thayipha i-1 isifo sikashukela;
- i-ketoacidosis, ikhesa, i-precoma, inqobo nje uma lezi zimo ze-pathological zakhiwa ngesisekelo sikashukela i-mellitus;
- iminyaka efinyelela eminyakeni eyi-18;
- ukungasebenzi kwesibindi nezinso.
Ezigulini esezikhulile futhi uma kwenzeka zingondleki kahle, umuthi okukhulunywa ngawo unqunyelwe, inqobo nje uma ukwelashwa kuzobe kungaphansi kokuqondisa kukadokotela. Imiphumela emibi engaba khona:
- i-hypoglycemia, izimpawu zalesi simo se-pathological: ukwazi ukungasebenzi kahle, ukusikeka, ukulamba okungapheli, ukungabekezeleleki, ukukhathazeka, isicanucanu, ikhanda;
- i-hyperhidrosis;
- ushintsho ekushweni kwenhliziyo.
Ukuqhathanisa kweMetformin neDiabetes
Ukufana
Zombili lezi zidakamizwa zitholakala ngendlela yepilisi. Izakhi ezisebenzayo eziqukethwe ukwakheka kwazo zisebenza ngomgomo ofanayo. Lezi zimali zingeqembu elilodwa lezidakamizwa. Izinkomba zokusetshenziswa kwazo ziyefana. Ngakho-ke, izidakamizwa ziyashintshana. Azinqunyelwe ngesikhathi sokukhulelwa nokuqunjelwa.
Uyini umehluko?
I-Diabeteson neMetformin aqukethe izinto ezahlukahlukene ezisebenzayo. Owesibili wezidakamizwa ungasetshenziswa ukwelapha izingane ezingaphezu kweminyaka eyi-10. UDiabeteson futhi unemikhawulo eminingi yobudala obuqinile futhi ayinqunyelwe iziguli ezingaphansi kweminyaka engu-18. Umthamo wezinto ezisebenzayo nawo uhlukile. Ngalesi sizathu, kungahle kudingekile ukuphinda ulandise umthamo womuthi uma uhlelelwe ukufaka omunye umuthi kwesinye.
Yikuphi okushibhile?
IMetformin ibiza ama-ruble ayi-150-200. I-Diabeteson ingathengwa ngama-ruble angama-310-330. Ukuqonda ukuthi yisiphi isidakamizwa esishibhile, udinga ukuqhathanisa intengo yamaphakeji nokuqukethwe kwethebhulethi efanayo. IMetformin ibiza ama-ruble angama-185. (Ama-30 ama-pcs.). Intengo yesifo sikashukela ngama-ruble angama-330 (ama-30 ama-pcs.).
Yini engcono: Metformin noma Diabeteson?
Mayelana nokusebenza kahle, le mithi iyalingana. Zisebenza ngomgomo ofanayo. Kodwa-ke, umsebenzi ophakeme we-Diabeteson ufinyelelwa isikhathi eside - phakathi namahora we-6 okuqala ngemuva kokuthatha umthamo womuthi. Ijubane lokusebenza kweMetformin liphezulu: inani eliphakeme lokusebenza lisebenza ngemuva kwamahora ama-2. Ngakho-ke, izinguquko ezinhle ngesikhathi sokwelashwa nalesi sidakamizwa zenzeka ngokushesha.
Ukubuyekezwa kweziguli
UValentina, oneminyaka engama-38, uStary Oskol
Nginesifo sikashukela sohlobo 2, ukukhuluphala, izinkinga zenhliziyo. Ngiyayemukela iMetformin. Ngigculisekile ngomphumela, ngoba umkhiqizo usebenza ngokushesha kunama-analogues.
UMarina, oneminyaka engama-42, u-Omsk
Udokotela unqume uDiabeteson. Esigabeni sokuqala sale nkathi yokwelashwa, kwavela imiphumela emibi: isicanucanu, ikhanda. Imiyalo ithi kancane kancane inyamalala, kodwa kimi lokhu akwenzekanga. Kwadingeka ngishintshe umuthi ngiwuse elinye ikhambi.
Ukubuyekezwa kodokotela mayelana neMetformin neDiabeteson
I-Tereshchenko E.V., i-endocrinologist, iminyaka engama-52, iKhabarovsk
IMetformin ingumuthi omkhulu. Ngiyabela iziguli isikhathi eside. Emiphumeleni emibi, isifo sohudo sivame ukwenzeka. Leli thuluzi lifana nokwejwayelekile kwe-lipid metabolism. Ngokuselapha, isisindo somzimba siyancipha.
UShishkina E.I., i-endocrinologist, iminyaka engama-57, uNizhny Novgorod
Isifo sikashukela ezimweni eziningi sinconywa esigabeni sokuqala sikashukela. Siyabonga kuye, ezigulini ezinalokhu kutholwa, izinkinga zitholakala kaningi. Umuthi unomphumela oyinkimbinkimbi: akagcini nje ngokunciphisa izinga le-glucose, kodwa futhi uthinta ukwakheka kwegazi, ukwakheka kwezindonga zemithambo yegazi, kuvamisa izinqubo ze-metabolic.
