I-Pentoxifylline NAS yisidakamizwa esinqunyelwe ukunciphisa imithambo yegazi kanye nokwenza ngcono ukuhamba kwegazi.
Igama Lezwe elingafanele
I-Pentoxifylline.
I-Pentoxifylline NAS yisidakamizwa esinqunyelwe ukunciphisa imithambo yegazi kanye nokwenza ngcono ukuhamba kwegazi.
I-ATX
Ikhodi ye-ATX yi-С04AD03.
Khipha amafomu nokwakheka
Amaphilisi
Umkhiqizo uyatholakala ngohlobo lwamathebulethi e-enteric-camera. Ithebhulethi ngayinye iqukethe u-100 mg wezithako ezisebenzayo. Into esebenzayo yesidakamizwa yi-pentoxifylline.
Uhlobo olungekho
Ngezinye izikhathi iziguli zibheka amaphilisi we-pentoxifylline. Leli fomu lesilinganiso alikho. Izibhebhe zalo muthi zinezakhiwo ezifanayo ngenxa yegobolondo elikhethekile elikuvumela ukuba ulethe into esebenzayo emathunjini. Lokhu kuqinisekisa ukumuncwa kahle kanye nokusatshalaliswa kwalo muthi.
IPentoxifylline-NAN itholakala kuphela kwifomu lethebhulethi.
Isenzo se-Pharmacological
Into esebenzayo yesidakamizwa i-methylxanthine derivative. Inomphumela we-vasodilating kwimithambo ye-peripheral, ikhulisa i-lumen yabo futhi igqugquzela ukuhamba kwegazi okulula.
Umphumela wesidakamizwa unikezwa ukuvimbela kwe-enosme phosphodiesterase. Kulokhu, i-cyclic adenosine monophosphate (cAMP) inqwabelana kuma-myocyte aqukethe ezindongeni zemithambo.
Ithuluzi lithinta ngqo izakhiwo zokuphamba kwegazi. I-Pentoxifylline ibambezela inqubo yamaplathiging gluing, inciphisa ukubonwa kwe-plasma, yehlise izinga le-fibrinogen embhedeni we-vascular.
Ngaphansi kwethonya lomuthi, ukumelana okuphelele kwemithambo yegazi kuyancipha. Ukwenza ngcono ukujikeleza kwegazi kunomthelela ekunikezelweni kwezicubu ezisebenza ngokwengeziwe ne-oksijini nezinto ezibalulekile empilweni. I-Pentoxifylline inomphumela ongcono kakhulu emikhunjini yamaphethelo nobuchopho. Ukuncipha okuncane kwemikhumbi ye-coronary nakho kuyenzeka.
I-Pharmacokinetics
Ngemuva kokungena egazini, isakhi esisebenzayo sibhekana nokuguqulwa kwe-metabolic. Ukuhlushwa kwe-metabolite ephumela ku-plasma kudlula ukuqoqwa kokuqala kwento esebenzayo izikhathi ezi-2. I-Pentoxifylline uqobo nesenzo sayo se-metabolite ezitsheni zomzimba.
Umuthi ucishe uguqulwe ngokuphelele. Igcotshwa ikakhulu ngomchamo. Ukuqedwa kwesigamu sempilo kungamahora ayi-1.5. Kufika ku-5% wesidakamizwa esikhishwa ngamathumbu.
Igcotshwa ikakhulu ngomchamo. Ukuqedwa kwesigamu sempilo kungamahora ayi-1.5.
Yini esiza iPentoxifylline NAS?
Umuthi ukhonjiswa kulezi zimo ezilandelayo:
- i-arrososososis ebucayi;
- i-arterial hypertension;
- ukuphazamiseka kokugeleza kwegazi emithanjeni yangaphandle;
- ischemic stroke;
- ukwehluleka kokujikeleza;
- ama-trophic pathologies ahlotshaniswa nokuphazamiseka kokujikeleza (izilonda ezindexekile, ukuqina kwesithwathwa, ushintsho lobugebengu);
- isifo sikashukela i-angiopathy;
- ukwehlukanisa endarteritis;
- ama-neuropathies wemvelaphi ye-vascular;
- izinkinga zokujikeleza endlebeni yangaphakathi.
Contraindication
Ukuxhumana kokusebenzisa umuthi yilezi:
- hypersensitivity yomuntu ngamunye kwinto esebenzayo nezinye izinto ezakha ukwakheka;
- ukuntuleka kwe-lactase;
- ukopha okukhulu;
- isikhathi esibuhlungu ngemuva kokuqothuka kwe-myocardial;
- ukonakala kwesilonda se-mucous membranes sethambo lesisu;
- profiles hemorrhages ekuxhumaneni kwamehlo;
- i-hemorrhagic diathesis;
- ukuzwela komuntu kokunye okususelwa ku-methylxanthine.
Ngokunakekela
Ukuqaphelisisa ikakhulukazi lapho usebenzisa lo muthi kufanele kuqashelwe kubantu abanokwehluleka kwesibindi, ngoba le ndlela yokuthambekela ithinta ama-pharmacokinetics e-pentoxifylline.
Ukulawulwa ngudokotela kuzodingeka futhi lapho:
- ukwehla njalo komfutho wegazi;
- isiguli sinezindlela ezinzima ze-arrhythmia;
- ukungasebenzi kahle kwe-hepatic;
- ukusetshenziswa okufanayo kwama-anticoagulants;
- ukuthambekela kokopha;
- inhlanganisela yomuthi nezidakamizwa ze-antidiabetes.
Ungayithatha kanjani iPentoxifylline NAS?
Umthamo wesidakamizwa ukhethiwe ngokuhlukile ngokuya kobunzima besifo. Umthamo owodwa ojwayelekile ngu-200-400 mg. Amacwecwe athathwe izikhathi ezi-2 noma ezi-3 ngosuku. Ukutholwa okungcono, udinga ukubaphuza ngemuva kokudla, ukuphuza nenani lamanzi elidingekayo. Umthamo omkhulu wezinsuku zonke we-pentoxifylline ngu-1200 mg.
Ngoshukela
I-Pentoxifylline iyindlela yokuvimbela ukuphazamiseka kwe-trophic okubangelwa ukungalingani ekutholakaleni kwesifo sikashukela i-mellitus. Umuthi usiza ukuhlinzeka izitho ngenani elanele lezakhi zomzimba, ukuvimbela ukukhula kwe-neuropathy, nephropathy, retinopathy.
I-Pentoxifylline-NAN ithathwa amahlandla ama-2 noma ama-3 ngosuku ngemuva kokudla, igezwe phansi ngenani lamanzi elidingekayo.
Umthamo womuthi ezigulini ezinesifo sikashukela ukhethiwe ngamunye. Udokotela kufanele acabangele ubungozi kanye nokuhlangana okungenzeka kwe-pentoxifylline ngemithi ethathwe yisiguli. Ezimweni eziningi, abantu abanesifo sikashukela bathola umthamo ojwayelekile.
Isicelo sokwakha umzimba
Umuthi usetshenziswa ngabasubathi ukwenza ngcono ukujikeleza kwe-peripheral, okunikeza izicubu umoya-mpilo owanele ngesikhathi sokuqeqeshwa.
Imithamo yokuqala yabasubathi yizingcwecwe ezi-2 izikhathi ezi-2 ngosuku. Kuyadingeka ukunamathela kule regimen isikhashana ukuze uqiniseke ukuthi ayikho imiphumela emibi. Kancane kancane, umthamo ungangezelelwa kumathebhulethi angama-3-4 umthamo ngamunye.
Kunconywa ukuthi ubonane nodokotela ngaphambi kokuthenga iPentoxifylline ngezinhloso zezemidlalo. Ukuzelapha kungaba nomthelela omubi esimweni somzimba.
Imiphumela emibi yePentoxifylline NAS
Ukuthatha lesi sidakamizwa kungahambisana nokuvela kwemiphumela ethile engafuneki. Engxenyeni yesistimu yenhliziyo, ukuphazamiseka kwesigqi senhliziyo, ukwehla okuqhubekayo komfutho wegazi, ukuwohloka kwamathambo, i-edema yezicubu zomzimba kungavela.
Amapheshana wesisu
Ukuvela okungenzeka:
- ukuphazamiseka kwesitulo;
- ukuqhakaza;
- isicanucanu
- ukuhlanza
- ukwanda kwesisulu.
Izitho zeHematopoietic
Ukusuka ohlelweni lwe-hemopoietic, lokhu kusabela okulandelayo okungathandeki kungenzeka:
- i-thrombocytopenia;
- i-anemia
- i-pancytopenia;
- i-leukemia, neutropenia;
- thrombocytopenic purpura.
Isistimu yezinzwa ephakathi
Kwangathi kungaphendulwa ekwelashweni ngokubonakala kwe:
- vertigo;
- ikhanda;
- ukungaboni kahle
- i-hallucinatory syndrome;
- i-paresthesia;
- i-meningitis;
- ukubanjwa
- ukuthuthumela
- dissomnia;
- ukukhuphula okukhulu;
- ukubuyiselwa emthanjeni.
Allergies
Kungenzeka:
- ukusabela kwe-anaphylactoid;
- i-necrolysis enobuthi;
- spasm yemisipha ebushelelezi ye-bronchi;
- i-angioedema.
Imiyalo ekhethekile
Ukunakekelwa kumele kuthathwe lapho kuthathwa umkhiqizo okokuqala. Uma kwenzeka ukusabela kwe-anaphylactic, yeka ukwelashwa futhi ufune usizo lodokotela.
Ukuqapha kumele kusetshenziswe lapho kuthathwa okokuqala iPentoxifylline-NAN okokuqala.
Uma i-Pentoxifylline ibekelwe isiguli esinokwehluleka kwenhliziyo okungapheli, kuyadingeka ukuthi kuqala sinikeze isinxephezelo sokuphazamiseka kokujikeleza kwegazi.
Ukusetshenziswa isikhathi eside kwesidakamizwa kudinga ukuqashwa kwesimo segazi esijikelezayo. Ukuhlaziywa kumele kuthathwe maqondana nokuthi kungenzeka ukwakheka kwegazi okungalimazi.
Iziguli ezinenkinga yokusebenza kwe-renal kufanele zihlolwe ngezikhathi ezithile ukubheka isimo sezinso lapho zithatha umuthi. Ukwehla kwe-pentoxifylline kukhubazeka uma imvume ye-creatinine incishiswa yaba ngu-30 ml / min.
Umthamo ekugugeni
Umthamo wansuku zonke wabantu asebekhulile ukhethiwe kucatshangelwa izici zesiguli ngasinye. Udokotela kufanele akhumbule ukuthi ngobudala, ukusebenza kwe-renal kuyancipha, okungaba yisizathu sokunqunyelwa kokuqedwa komuthi. Kulokhu, kuyadingeka ukunquma umthamo omncane we-pentoxifylline.
Imithamo yansuku zonke yePentoxifylline-NAN yabantu asebekhulile ikhethiwe kucatshangelwa izici zesiguli ngasinye.
Isabelo sezingane
Ayikho imininingwane ngokusetshenziswa kwezidakamizwa ekwelapheni iziguli ezikuleli qembu.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Ukuqokwa komuthi ngesikhathi sokukhulelwa akunconywa ngenxa yokuntuleka kwedatha. Uma kunesidingo, udinga ukubonana nochwepheshe ozohlola ubungozi obungahle bube khona ku-fetus.
Uma kunesidingo sokusebenzisa i-pentoxifylline ngesikhathi sokuncelisa ibele, ukunakekelwa kufanele kuthathwe ukuze kudluliselwe ingane ekuondleni okungelona iqiniso. Into esebenzayo yesidakamizwa ingadlula ubisi lwebele.
Ukweqisa
Uma uphinda ngokweqile umthamo ophakanyisiwe, isicanucanu, ukuhlanza, isiyezi, i-hypotension kungenzeka. Ngesinye isikhathi, ukubonakala kokushisa komzimba okukhuphukile, i-tachycardia, i-arrhythmias yenhliziyo, ukopha kwangaphakathi.
Izimpawu ezingenhla kufanele zimiswe ngaphansi kokuqashwa kwabasebenzi bezokwelapha. Ukwelashwa okubonakalayo kuyasetshenziswa, kuya ngesimo sesiguli.
Uma umthamo ophakanyisiwe wePentoxifylline-NAS udlulwa kaningi, kungaba sengathi kunesicanucanu nokuhlanza.
Ukuxhumana nezinye izidakamizwa
Ithuluzi lingathuthukisa umsebenzi wezidakamizwa ze-antiglycemic. Ngenxa yalokhu, kungadingeka ukulungiswa komthamo.
Ngokuhambisana nabaphikisi be-Vitamin K, i-pentoxifylline yehlisa amandla okubamba kwegazi. Ukusetshenziswa kwesikhathi eside okuhlangene kungaholela ekwakhiweni kokuphuma kwegazi nezinye izinkinga.
Into esebenzayo ingakhuphula i-theophylline egazini negazi elihlanganisiwe.
Ukuqunjelwa umuthi kungakhuphuka lapho kuhlangene ne-ciprofloxacin.
Ukuhambisana notshwala
Ukuphuza ngesikhathi sekwelashwa akukanconywa. Utshwala bunganciphisa ukusebenza kwelashwa.
Ama-Analog
Ama-analoggs aleli thuluzi yilawa:
- I-Agapurin;
- I-Flowerpot;
- I-Latren;
- Pentilin;
- I-Pentoxypharm;
- I-Pentotren;
- Trental.
Imibandela yekhefu lekhemisi
Ngokuya ngomuthi kadokotela.
Ngingakwazi ukuthenga ngaphandle kadokotela
Cha.
Intengo ye-Pentoxifylline NAS
Kuya ngendawo yokuthenga.
Izimo zokugcina zomuthi
Kuyadingeka ukugcina kumazinga okushisa angabi ngaphezu kwe- + 25ºС.
Isikhathi sokuphelelwa yisikhathi
Ngokuya ngaphansi kwezimo zokugcina, umuthi ulungele ukusetshenziswa kungakapheli iminyaka emi-3 kusukela ngosuku lokukhishwa.
Umkhiqizi
Kwenziwa yinkampani ye-Academpharm.
Kwenziwa yinkampani ye-Academpharm.
Ukubuyekezwa kwePentoxifylline NAS
Odokotela
UGalina Mironyuk, udokotela wezokwelapha, eSt
I-Pentoxifylline iyisidakamizwa esisebenzayo sokwenza ngcono ukuhamba kwegazi. Inomthelela ekwandeni kwemithambo yegazi esikhunjeni, ulwelwesi lwama-mucous. Ithuluzi elibalulekile kubantu abanesifo sikashukela esibi. Isiza ukugwema ukuthuthukiswa kwama-pathologies amaningi.
Mina uqobo ngiyithatha kaningana ngonyaka ngenxa yezinkinga ezinomfutho wegazi ophakeme. Umuthi uphephile ngokuphelele uma usetshenziswa ngokuya ngemiyalo. Kodwa angikucebisi ukuthi uzithenge ngokwakho, qala uthintane nochwepheshe.
U-Andrey Shornikov, udokotela wezifo zenhliziyo, eMoscow
Leli thuluzi liyaziwa kubantu abanenkinga yokujikeleza kokujikeleza kwegazi. Ibekelwe imivimbo kanye namanye ama-pathologies lapho kudingekile ukubuyisela ukuhamba kwegazi okujwayelekile. Ngisho nabasubathi bazithokozisile zonke izinzuzo zako futhi basebenzisa umuthi ukuze ubuyisele masisha izicubu ngemuva kokuqeqeshwa kanzima.
I-Pentoxifylline ayibizi futhi iyasebenza, kepha udinga ukubona udokotela ngaphambi kokuyithatha. Kwezinye izimo, kungadala imiphumela emibi evela ezithweni zezinzwa, njengokulahleka kwezindlebe noma ukubanjwa komzimba. Ukwelapha kudinga ukubhekwa nguchwepheshe. Ukuqapha njalo isimo somzimba kuzosiza ekugcineni impilo yakho.
Iziguli
U-Antonina, oneminyaka engama-57, u-Ufa
Ngiye kudokotela ezinyangeni ezimbalwa ezedlule ephathelene nekhanda. Ngemuva kokungihlola, waphetha ngokuthi kungenxa yomfutho wegazi ophakeme. Amanani lawo ayengaphakeme kakhulu, kepha impilo yami yonke nganginomqondo oguqukayo, ngakho-ke ukushintshashintsha okunjalo kwathinta umzimba.
Udokotela uthe kusesekuseni kakhulu ukunquma izidakamizwa ezijwayelekile zokwelashwa kwe-hypertension, futhi zinemiphumela emibi emningi. Ululeke ukuthi athathe iPentoxifylline. Uthe wehlisa umfutho futhi uthuthuka nokugeleza kwegazi. Ngaphambi kokuqala ukwelashwa, wadlula zonke izivivinyo ukubheka isimo sezinso nesibindi.
Ngiphuza amaphilisi nsuku zonke ngaphandle kokuphuza idosi elilodwa. Ubuhlungu bekhanda abusekho, ngizwa kahle. Manje ngaluleka wonke umuntu ojwayelene nezinkinga ezifanayo.
UDenis, oneminyaka engama-45, uSamara
Sekuphele iminyaka engu-15 ngigula nginesifo sikashukela. Ekuqaleni, ukudla nemidlalo kwasiza ukugcina amazinga ashukela ajwayelekile, kodwa-ke kwadingeka ngiye ekhemisi. Lesi sifo siyaqhubeka yize ngithola imithamo ephezulu yemishanguzo yokuhlaselwa kwezifo nsuku zonke.
Kancane kancane, izimpawu zomonakalo ezithweni ezahlukahlukene zaqala ukuvela. Udokotela utuse ukuthi bathenge iPentoxifylline ukumisa ukuqhubeka kwabo. Sekuphele izinyanga eziyisithupha ngiphuza umuthi. Ngalesi sikhathi, ngaba nomuzwa wokuthi isimo sami sasesingcono. Ukubuyisela ukujikeleza kwegazi, ngasiza umzimba wami ukulwa nalesi sifo. Ngisho nekhanda selibe licocekile, ngoba umuthi ubuye uthuthukise nokugeleza kwegazi okuphathelene nokuqina. Ngincoma kuwo wonke umuntu.
UKrisitina, oneminyaka engama-62, eMoscow
Udokotela unqume uPentoxifylline ngemuva kokushaywa unhlangothi. Ngasikhathi sinye ezinye izidakamizwa. Angazi ukuthi ngingambonga ini, kepha ngemuva kwezinyanga ezimbalwa zokwelashwa isimo sami saba ngcono. Ngemuva kokushaywa unhlangothi, ngacishe angangishukumisi isandla, manje sengingathatha izinto ezincane, okungenani ngizinikele ngandlela thile.
Ngiyabonga ngalo muthi nakudokotela okhethe ukwelashwa okufanele.
