I-Diabefarm MV ibhekisela kuma-ejenti anamandla we-hypoglycemic, okuhloswe ngawo ukusetshenziswa komlomo kuphela. Amacwecwe asetshenziswa ekwelapheni isifo sikashukela sohlobo 2.
Igama Lezwe elingafanele
I-Diabefarm MV ibhekisela kuma-ejenti anamandla we-hypoglycemic, okuhloswe ngawo ukusetshenziswa komlomo kuphela.
INN: IGlyclazide.
I-ATX
Ikhodi ye-ATX: A10BB09.
Khipha amafomu nokwakheka
Umuthi uyatholakala ngesimo samathebulethi ngokukhishwa okuguquliwe. Banesimo esicwebezelayo, kuthebhulethi ngayinye umugqa wokuhlukanisa owenziwe ngophawu. Umbala omhlophe noma ukhilimu.
Into esemqoka esebenza yi-gliclazide. Ithebhulethi eyi-1 iqukethe ama-30 mg noma ama-80 mg. Izinto ezengeziwe: i-povidone, ushukela wobisi, i-magnesium stearate.
Umuthi lo ukhiqizwa emaphaketheni amaqabunga amathebula ayi-10 lilinye (amatheshisi ayi-6 asepakethe lamakhadibhodi) kanye namaphilisi angama-20 kwiphakethe, ama-3 ama-blacks asekhabhathini lekhadibhodi. Futhi, umuthi uyatholakala emabhodleleni epulasitiki wezingcezu ezingama-60 noma ezingama-240 lilinye.
Isenzo se-Pharmacological
Amathebulethi angasho ukuthi avela esizukulwaneni sesibili se-sulfonylurea. Ngokusebenzisa kwabo, kukhona ukukhuthaza okusebenzayo kokuvikelwa kwe-insulin ngamaseli we-beta wamanyikwe. Kulesi simo, ukuzwela kwezicubu ezixakile ku-insulin kuyanda. Umsebenzi wama-enzyme ngaphakathi kwamaseli nawo uyakhuphuka. Isikhathi esiphakathi kokudla nokuqala i-insulin secretion sincishiswa kakhulu.
Amathebulethi aphazamisa ukuthuthukiswa kwe-atherosulinosis kanye nokuvela kwe-micothrombi.
I-Gliclazide inciphisa ukunamathela kweplatelet kanye nokuhlangana. Ukuthuthukiswa kweziqeshana zegazi le-parietal kuyayeka, futhi umsebenzi we-fibrinolytic wemikhumbi uyakhuphuka. Ukuvuleka kwezindonga ze-vascular kubuyela kokujwayelekile. Iqoqo le-cholesterol egazini liyancipha. Izinga lama-radicals mahhala nalo liyancishiswa. Amathebulethi aphazamisa ukuthuthukiswa kwe-atherosulinosis kanye nokuvela kwe-micothrombi. I-microcirculation iyathuthuka. Ukuzwela kwemithambo yegazi ku-adrenaline kuncishisiwe.
Lapho i-nephropathy yesifo sikashukela kwenzeka ngenxa yokusetshenziswa isikhathi eside kwalo muthi, i-proteinuria iyancipha.
I-Pharmacokinetics
Ngemuva kokuphathwa ngomlomo kwalesi simeli se-hypoglycemic, into esebenzayo idonswa ngokushesha kwizitho zepheshana lesisu. Ukugxiliswa okuphezulu kakhulu egazini kuqashelwa amahora ama-4 emva kokuba into ingene emzimbeni. I-Bioavailability kanye namandla okubopha ezinhlakeni zamaprotheni ziphakeme impela.
Metabolism kwenzeka esibindini. Ama-metabolites aphambili awunawo umphumela we-hypoglycemic, kodwa anomthelela omuhle kwi-microcirculation. Isigamu sempilo singamahora ayi-12. Kuthululwa emzimbeni wezinso ngendlela yama-metabolites amakhulu.
Metabolism kwenzeka esibindini.
Izinkomba zokusetshenziswa kwe-Diabefarma MV
Isidakamizwa sinconyelwa ukuvikela isifo sikashukela sohlobo 2. Kuyasiza ukuvimbela i-microvascular (ngendlela ye-retinopathy nephropathy) kanye nezinkinga ze-macrovascular, ezifana ne-myocardial infarction.
Ngaphezu kwalokho, umuthi ukhonjiswa isifo sikashukela sohlobo 2, uma ukudla, ukuvivinya umzimba kanye nokunciphisa umzimba kunganikeli imiphumela. Yisebenzise futhi nokwephulwa kwe-microcirculation ebuchosheni.
Contraindication
Kunezindlela eziningi zokuphikisana ngokuphelele nokusetshenziswa kwe-Diabefarma MV. Phakathi kwazo kukhona:
- thayipha i-1 isifo sikashukela;
- i-precoma;
- ukwehluleka kwezinso kanye nesibindi;
- ukulimala okubanzi noma ukulimala kwesikhumba okufuna ukwelashwa kwe-insulin;
- ukuvinjwa kwamathumbu;
- i-hypoglycemia;
- ukwephulwa emsebenzini wohlelo lwe-hematopoietic;
- isikhathi sokukhulelwa nokukhulelwa;
- iminyaka efinyelela eminyakeni eyi-18;
- ukungabekezelelani komuntu ngamunye ezingxenyeni zomuthi.
Ukuhlukumeza okuhlobene kuboniswe kwimiyalo esetshenziswayo yile: umkhuhlane, ukungasebenzi kahle kwe-yegilo gland kanye nokusebenzisa kabi utshwala.
Ungayithatha kanjani iDiabefarm MV?
Amacwecwe enzelwe ukuphathwa ngomlomo kuphela. Thatha umuthi ihora elilodwa ngaphambi kokudla. Kunconywa ukuphuza amaphilisi kabili ngosuku, ekuseni nakusihlwa. Imithamo ihlala ibekelwa umuntu ngamunye, okubangelwa ubudala nobulili besiguli, ubukhulu besifo, izinkomba zokuzila ushukela wegazi kanye namahora ama-2 ngemuva kokudla.
Umthamo wokuqala awudluli kuma-80 mg ngosuku. Ngokwezinkomba zomtholampilo, umthamo ungandiswa ube ngu-160 mg. Umthamo omkhulu wansuku zonke akufanele udlule kuma-320 mg ngosuku.
Imiphumela emibi ye-Diabefarma MV
Uma umthamo ungalungile noma ukudla kungalandelwa, i-hypoglycemia ingaqhamuka. Isimo esifanayo sihambisana: nokuqaqamba kwekhanda, isiyezi, ukukhathala okujwayelekile, ukukhathazeka, ukusabela kancane, ukungakhathaleli, ukubuka okuphansi, i-bradycardia, ukwehluleka.
Ukusabela okuvela kwezinye izitho nezinhlelo nakho kungenzeka. Phakathi kwazo kukhona:
- i-anemia
- i-thrombocytopenia;
- umuzwa wobunzima esiswini;
- umsebenzi owengeziwe wama-enzyme wesibindi;
- i-cholestatic jaundice;
- i-urticaria;
- ku-gynecology: ukulunywa kwe-mucosa;
- ukuqubuka kwesikhumba okuhambisana nokulunywa.
Ukususa i-hypoglycemia, umuntu unikezwa ushukela. Uma isiguli singazi lutho, isixazululo se-glucose esingu-40% sifakwa ngaphakathi noma emzimbeni ngendlela eyi-1-2 mg ye-glucagon. Ngemuva kokuthi umuntu abuyele ukwazi, udinga ukumondla ngokudla okugcwele ama-carbohydrate. Uma i-edema yamakhemikhali ivela, kusetshenziswa i-dexamethasone.
Phakathi kokusabela okungekuhle komzimba kulo muthi, ukuqunjelwa kwesikhumba kuyaphawulwa, kuhambisane nokulunywa.
Umthelela ekhonweni lokulawula izindlela
Ngoba ukuthatha umuthi kungaholela ku-hypoglycemia, ngokulandelana, kwehlise izinga lokuphendula, kungcono ukunciphisa umkhawulo wokushayela imoto nokulawula ezinye izindlela ezidinga ukunakwa okwandayo kokunakwa.
Imiyalo ekhethekile
Kanye nokuthatha umuthi wokudla, ukudla okunempilo okusekelwe ekudleni okune-khalori ongama-carbohydrate kanye nokuhlanzeka kuyadingeka. Kulokhu, ukuqapha okungapheli kwamazinga kashukela (ngaphambi nangemva kokudla) kuyadingeka. Kufanele njalo ucabangele ukuthi kungenzeka ukuthi kusetshenziswe i-insulin ngokwengeziwe ku-mellitus ebunjiwe nangaphambi kwezinqubo zokuhlinzwa.
Uma ushesha, i-hypoglycemia enkudlwana ingakhula. Umphumela ofanayo ubonwa ngokusetshenziswa isikhathi eside kwezidakamizwa ezingezona ezingama-antiidal kanye ne-ethanol. Ukulungiswa kwedosi kuyadingeka ezimweni zezinguquko ekudleni nasekuqineni ngokweqile komzimba nangokomzwelo.
Ngokunganeleki kwe-pituitary-adrenal futhi kubantu asebekhulile, ukuthambekela kokuthola usizo kuma-hypoglycemic agents kuyanda.
Sebenzisa ebudaleni
Abantu abadala bayelulekwa ukuthatha lesi sidakamizwa ngokucophelela okukhulu, ngoba lesi sigaba sabantu sisengozini enkulu yokuthuthuka kwe-hypoglycemia. Kubantu asebekhulile, ukusabela okungekuhle kwenzeka kaningi kakhulu. Badinga ukubhekisisa amazinga abo kashukela njalo.
Abantu abadala bayelulekwa ukuthatha lesi sidakamizwa ngokucophelela okukhulu, ngoba lesi sigaba sabantu sisengozini enkulu yokuthuthuka kwe-hypoglycemia.
Isabelo sezingane
Ayibekelwe izingane ezingaphansi kweminyaka engu-18.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Ukusetshenziswa kwesidakamizwa ngesikhathi sokukhulelwa nokuqunjelwa kuyaphulwa, njengoba I-gliclazide inempahla yokungena ekuvinjelweni kwe-placental kanye nobisi lwebele, olungalimaza umntwana osakhula nosanda kuzalwa.
Isicelo sokusebenza kokulimala kwezinso
Ayinqunyelwe izinhlobo ezinzima zokwehluleka kwezinso.
Sebenzisa umsebenzi wesibindi okhubazekile
Ngokuphulwa okukhulu kwesibindi, lesi sidakamizwa asinqunyelwe.
Ukweqisa
Ngomthamo ofanele, amacala e-overdose awenzeki. Uma ngephutha uthatha umthamo omkhulu kakhulu womuthi, ungathola izimpawu ezinjengokuthi: ubuthakathaka obujwayelekile, ukulahlekelwa ukwazi, ukujuluka okubandayo, umoya omubi. Ukwelashwa kwenziwa ngokudla ama-carbohydrate noma ukuxubha izindebe noju. Kulesi simo, isiguli kufanele siyiswe esibhedlela ngokushesha.
Uma ngephutha uthatha umthamo omkhulu kakhulu womuthi, ungahle ulahlekelwe ukwazi.
Ukuxhumana nezinye izidakamizwa
Umphumela we-Hypoglycemic ukhuphuka ngokusetshenziswa kanyekanye kwamathebulethi aqukethe i-pyrazolone, amanye ama-salicylates, ama-sulfonamides, ama-phenylbutazone, i-caffeine, i-theophylline ne-MAO inhibitors.
Ama-block adrenergic block angakhethi ukwandisa ubungozi be-hypoglycemia. Kulokhu, ukwethuka, i-tachycardia kuvame ukuvela, ukujuluka kuyanda.
Lapho kuhlanganiswa ne-acarbose, umphumela wokufakwayo we-hypoglycemic uyaphawulwa. I-Cimetidine inyusa into esebenzayo egazini, okuholela ekuvinjelweni kohlelo lwezinzwa oluphakathi nendawo kanye nokwazi ukungalungiseki.
Uma uphuza ngesikhathi esifanayo i-diuretics, izithasiselo zokudla, ama-estrogens, ama-barbiturates, ama-rifampicin, umphumela we-hypoglycemic womuthi uyancishiswa.
Ukuhambisana notshwala
Ungathathi umuthi ngasikhathi sinye notshwala. Lokhu kungaholela ekutheni kube nezimpawu ezengeziwe zokuphuza, okukhonjiswa ngobuhlungu besisu, isicanucanu, ukuhlanza kanye nekhanda elinzima.
Ama-Analog
I-Diabefarm inezinhlobo eziningi zezifaniso ezifanayo nayo ngokuya ngezinto ezisebenzayo nomphumela wokwelapha. Okuvame kakhulu phakathi kwabo yilezi:
- IGlllada;
- UGlidiab;
- Glyclazide Canon;
- Glyclazide-AKOS;
- Isifo sikashukela;
- Diabetesalong;
- UDiabinax.
Imibandela yekhefu lekhemisi
Lo muthi ungathengwa emakhemisi ngencazelo kadokotela.
Ngingakwazi ukuthenga ngaphandle kadokotela?
Cha.
Intengo
Izindleko eRussia zisukela kuma-ruble ayi-120 kuya kwangama-150. iphakheji ngayinye futhi kuya ngomthamo, ukupakishwa, umakhi, isifunda sokuthengiswa kanye nezinsuku zemithi yasokhemisi.
Izimo zokugcina zomuthi
Gcina endaweni eyomile futhi emnyama lapho izingane zingafinyeleleki khona, esimweni sokushisa esingeqile ku-25 ° C. Gcina kuphela kwephakeji yangempela.
Isikhathi sokuphelelwa yisikhathi
Hhayi iminyaka engaphezu kwemi-2 kusuka ngosuku lokukhipha olukhonjiswe kwiphakheji yangempela.
Umkhiqizi
Inkampani yezokukhiqiza: Farmakor, Russia.
Ukusetshenziswa kwesidakamizwa ngesikhathi sokuqunjelwa kuyaphulwa.
Ukubuyekezwa
Iningi labodokotela, njengeziguli, baphendula kahle ngalo muthi.
Isifo sikashukela
UMarina, oneminyaka engama-28 ubudala, Perm
Amathebhulethi e-Diabefarma MV ashintshwa evela ku-Diabeteson. Ngingasho ukuthi ukusebenza kokuqala kuphakeme. Akukho kusabela okuhlukile okwenzekile; kubekezelelwa kahle. Ngiyayincoma.
UPavel, oneminyaka engama-43 ubudala, uSimferopol
Angincomi umuthi. Ngaphezu kokuyithatha njalo, ngangicasulwa kakhulu, ngaba nesiyezi njalo, futhi ngaso sonke isikhathi ngangibulala. Ushukela wegazi uphansi kakhulu. Kufanele uthathe omunye umuthi.
UKsenia, oneminyaka engama-35, eSt
Umuthi ushibhile futhi awunampilo emibi kunama-analogues abizayo. Izinga le-glucose libuyele kwelejwayelekile, ngazizwa ngingcono futhi ngiqaphile. Ukudla okusajwayelekile kusamele, kepha hhayi kaningi. Ngesikhathi sekwamukelwa, bekungekho miphumela emibi futhi cha.
Odokotela
Mikhailov V.A., endocrinologist, eMoscow
Amaphilisi we-Diabefarma MV avame ukubekelwa abantu abanesifo sikashukela sohlobo 2. Baqale ukuyikhipha muva nje, kodwa usevele wakwazi ukuzibonakalisa ohlangothini oluhle. Iningi leziguli, liqala ukulithatha, lizizwe lihle, alikhalazi ngokuphendula okungahambi kahle. Kuyabiza, okubuye kube yisiqinisekiso esichazayo.
ISoroka L.I., i-endocrinologist, i-Irkutstk
Kumkhuba wami, ngivame ukusebenzisa lesi sidakamizwa. Kwakunecala elilodwa kuphela le-hypoglycemia elinobunzima bokukhathazeka kwesifo sikashukela. Lesi yisibalo esihle. Iziguli ezizisebenzisayo zihlala ziphawula ukwanda kwamaglue kashukela.
