Umuthi ugcina umfutho wegazi ojwayelekile futhi uvimbela i-vasoconstriction. Inomphumela we-hypotensive futhi mnene we-diuretic. Kusetshenziswa ekwelapheni umfutho wegazi ophakeme. Ngokusetshenziswa isikhathi eside, kuvimbela ukwanda kwesisindo se-myocardial kubantu abadala nasezigulini esezikhulile.
I-ATX
C09CA07
Umuthi ugcina umfutho wegazi ojwayelekile futhi uvimbela i-vasoconstriction.
Khipha amafomu nokwakheka
Umenzi ukhipha umkhiqizo ngesimo samathebulethi okusaqanda. Into esebenzayo yi-telmisartan enanini lama-40 mg. Iphakheji liqukethe amaphilisi ayi-14 noma angama-28.
Isenzo se-Pharmacological
Into esebenzayo ivimba umphumela we-vasoconstrictor we-angiotensin. Isiza ukwehla kwegazi.
I-Pharmacokinetics
Ingeniswa ngokushesha, ingena ekujuleni kwegazi futhi ihlangana namaprotheni e-plasma. It is metabolized in the isibindi ukwakha izingxenye ezingasebenzi. Igcotshwe emgodini futhi ingcosana nomchamo.
Izinkomba zokusetshenziswa
Umuthi usetshenziswa ekwelapheni umfutho wegazi ophakeme. Ingabekwa ukuvikela izingqinamba zenhliziyo ngokumelene nesizinda somfutho wegazi ophezulu.
Contraindication
Kuphikisiwe ukuthatha imali kwezinye izimo:
- ukuvaleka kwemidumba ye-bile;
- imfundo eyandisiwe emzimbeni we-aldosterone;
- ukungezwani komzimba ezakhiweni zomuthi;
- ukungasebenzi kahle kwesibindi nezinso;
- isikhathi sokukhulelwa nokuncelisa;
- ukuphazamiseka okunamafa kwe-metabolism ye-fructose.
Iziguli ezingaphansi kweminyaka engu-18 ubudala azinqunyelwe lesi sidakamizwa.
Ungayithatha kanjani iMikardis 40
Kuyadingeka ukuthatha umkhiqizo ngokuya ngemiyalo yokusetshenziswa.
Kwabadala
Kuyadingeka ukuqala ukuthatha nge-20 mg ngosuku. Ukufeza umphumela ophinyiselwe ngokwengeziwe, ezinye iziguli zandisa umthamo ukuya kuma-40-80 mg ngosuku. Ezimweni ezinzima, umthamo ungakhushulelwa ku-160 mg ngosuku. Uma ukusebenza kwesibindi kukhubazekile, awukwazi ukuthatha ngaphezu kwe-1 ithebhulethi ngosuku. Iziguli zeHemodialysis ezinokulimazeka kwe-renal function azidingi ukulungisa umthamo. Yamukelwe ngasikhathi sinye ngokudla noma ngemuva. Isikhathi sokwelashwa sisuka ezinyangeni ezi-1 kuye kwezingu-2.
Okwezingane
Ukuphepha kokwamukelwa ezinganeni ezingaphansi kweminyaka engu-18 akufundwanga.
Kungenzeka yini ukuthi uphuze umuthi onesifo sikashukela
Umuthi ungasetshenziselwa isifo sikashukela sohlobo 2. Umuthi unomphumela omuhle ku-nephropathy yesifo sikashukela kanye ne-arterial hypertension.
Umuthi ungasetshenziselwa isifo sikashukela sohlobo 2.
Imiphumela emibi
Ithuluzi lingadala ukusabela okuhlukahlukene okungathandeki kusuka kuzitho nezinhlelo. Izibhebhe ziyeka ukuthatha uma imiphumela emibi ibonwa.
Amapheshana wesisu
Ukudla okucasulayo, isicanucanu, izinhlungu ze-epigastric kanye nezinguquko kuphrofayili yesibindi.
Izitho zeHematopoietic
I-anemia, hypercreatininemia, i-orthostatic hypotension kungenzeka. Ezimweni ezingavamile, ukwamukelwa kuholela ekwandeni kwe-creatinine egazini.
Isistimu yezinzwa ephakathi
Kukhona ukungasebenzi kwemisipha okungahleliwe, ukukhathala, ikhanda, ukudangala nesiyezi.
Eminye yemiphumela emibi yesipheshana emathunjini yi-nausea.
Kusuka ohlelweni lomchamo
Izifo ezithathelwanayo, i-edema.
Kusuka ohlelweni lokuphefumula
Ukukhwehlela kungavela okubonisa ukutheleleka kokuphefumula.
Kusuka ohlelweni lwe-musculoskeletal
Ukulimala kwemisipha nobuhlungu emuva.
Allergies
Ukungezwani komzimba kwenzeka ngendlela yokuvuvukala kwezicubu, i-urticaria, ukuqubuka kwesikhumba.
Imiyalo ekhethekile
Uma ukwelashwa nge-diuretics kwenziwa, kuhudulwa isisu noma ukugabha, umthamo uyancishiswa. Nge-unilateral noma i-artery stenosis ye-unilateral noma eyodwa, isidakamizwa sibekwa ngokuqapha. Ubungozi bokwandisa ukugcwala kwe-potassium esegazini banda uma kwenzeka izifo ezinzima zesibindi, izinso noma inhliziyo. Ngakho-ke, udinga ukulawula izinga le-creatinine ne-potassium egazini.
Ukuhambisana notshwala
Kwenqatshelwe ukuhlanganisa ukuthatha lo muthi nokusebenzisa iziphuzo eziqukethe i-ethanol.
Kwenqatshelwe ukuhlanganisa ukuthatha lo muthi nokusebenzisa iziphuzo eziqukethe i-ethanol.
Umthelela ekhonweni lokulawula izindlela
Kumele kuthathwe ukunakekelwa uma ushayela imoto, ngoba umuthi ungadala isiyezi nokukhathala. Ithuluzi lithinta ukunakwa kokunakwa.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Kuyenqatshelwa ukusebenzisa ngesikhathi sokukhulelwa. Ngaphambi kokuthatha umuthi, kufanele uyeke ukuncelisa ibele.
Ukweqisa
Nge-overdose, ingcindezi ihlehlela emazingeni abucayi. Isiyezi, izinhlungu emathempelini, ukujuluka nobuthakathaka kungavela. Ukwelashwa okubonakalayo kunqunyelwe, umuthi uyamiswa.
Ukuxhumana nezinye izidakamizwa
Ngaphambi kokusebenzisa, kubalulekile ukutadisha ukuxhumana nezinye izidakamizwa. Ithuluzi linyusa umphumela wokuthatha izidakamizwa ze-antihypertensive futhi lenyusa ukugcwala kwe-digoxin ku-plasma. Ngokwelashwa kwe-NSAID, ubungozi bokuthi umsebenzi wezinso ungasebenzi. Kuyadingeka ukulawula ukuqoqwa kwe-potassium nokusetshenziswa okuhlanganisiwe kwezithasiselo namalungiselelo aqukethe i-potassium (heparin). Ngokusetshenziswa kanyekanye nokulungiswa kwe-lithium, umphumela onobuthi emzimbeni uyanda.
Nge-overdose yesidakamizwa, isiyezi singabonakala.
Analogs of Mikardis 40
Eminye imishanguzo kadokotela esisiza ngomfutho wegazi ophezulu isatshalaliswa ekhemisi. Ungathenga ama-analogu wokukhiqiza wasekhaya nowangaphandle:
- Ikhadi
- Atacand
- UDiovan;
- I-Valz;
- IValsartan.
- Angiakand;
- I-blocktran;
- Aprovel;
- I-Candesartan;
- I-Losartan;
- I-Telpres (Spain);
- ITelsartan (India);
- I-Telmista (iPoland / iSlovenia);
- Teseo (Poland);
- I-Prirator (Germany);
- I-Tsart (India);
- I-Hipotel (i-Ukraine);
- Twinsta (Slovenia);
- I-Telmisartan-Teva (IHungary).
Le mithi ingaba ne-contraindication futhi ibangele imiphumela emibi. Ngaphambi kokuthatha umuthi kanye nama-analogues awo, kuyadingeka ukubonana nochwepheshe.
Imibandela yekhefu lekhemisi
I-Prescript Micardis iyatholakala ekhemisi.
Intengo
Izindleko ekhemisi zivela kuma-ruble angama-400. kufika ku-1100 rub.
Izimo zokugcina zeMikardis 40
Gcina amaphilisi ekhompyutheni emazingeni okushisa aze afike ku-+30 ° C.
Isikhathi sokuphelelwa yisikhathi
Impilo yeshalofu yesidakamizwa yiminyaka emi-4. Ngemuva kosuku lokuphela, umuthi uvunyelwe.
Ukubuyekezwa mayelana neMikardis 40
UMikardis 40 - isidakamizwa esivela kumkhiqizi uBeringer Ingelheim Pharma GmbH kanye ne-Co. KG, eJalimane. Ibekezelelwe kahle iziguli, ngokushesha iqala ukwenza isenzo. Emavikini okuqala angama-2-3 okwelashwa, imiphumela emibi ingahle ivele inyamalale ngokwayo.
Odokotela
U-Andrey Savin, udokotela wezifo zenhliziyo
I-Telmisartan ngumphikisi we-angiotensin II receptor. Into esebenzayo ivimbela ukuncipha kwe-lumen yemithambo yegazi. Umfutho wegazi uyancipha futhi ukuhla kwe-aldosterone ku-plasma yegazi kuyehla. Umuthi usiza ukuqeda uketshezi emzimbeni, ukwandise ukuphuma kwegazi le-renal.
UKirill Efimenko
Nginikeza ithebhulethi engu-1 ngosuku ezigulini. Ngokuya kobunzima besifo, ungangezelela umthamo. Ezimweni ezinzima, zingahlanganiswa ne-hydrochlorothiazide ngesilinganiso esifinyelela ku-25 mg ngosuku. Ukwelapha kungaholela ekwandeni kwama-enzyme wesibindi. Uma ukukhulelwa kumisiwe, ukwamukela kuyamiswa ukuze kungalimazi ingane. Lapho uhlela ukukhulelwa, umuthi awudli.
Iziguli
U-Ana, oneminyaka engama-38
Kwesinye isikhathi ingcindezi iyakhuphuka bese ikhanda libuhlungu. Isimo sithuthuka ngemuva kokuthatha i-ejenti ye-antihypertensive. Akuqali ukwenza isenzo ngokushesha, kepha umphumela uthatha amahora angama-24. Umuzwa omuhle lapho ikhanda lami lingalimali nengcindezelo ingaphansi kwemingcele ejwayelekile.
U-Elena, oneminyaka engama-45
Ngemuva kokuphuza umuthi, ukozela, ukuvuvukala kwemilenze kuvela futhi isilinganiso senhliziyo siyashesha. Angikukhuthazi ukuthatha ngaphezu kwama-20 mg ngosuku. Izimpawu zanyamalala ngemuva kwamasonto angama-2-3, futhi nganquma ukungayeki ukuzithatha. Imizwa ihamba kahle futhi ingcindezi ibuyele kwesejwayelekile. Ngihlela ukuthatha izinyanga ezingama-2-3.
U-Eugene, oneminyaka engama-32
Abazali bathenga leli thuluzi. Ukusebenza ngempumelelo, kwehlisa ingcindezi isikhathi eside. Sisebenzisa ekwelapheni umfutho wegazi ophakeme. Ngesikhathi sokulashwa, ubaba wathenga isifutho somphimbo ngenxa yokukhwehlela. Kwavela ukuthi lokhu kungumphumela wecala osanyamalala ngemuva kwezinsuku ezingama-6-7. Kuyabiza, kusiza ngokushesha. Wanelisekile ngomphumela.
