I-Tujeo isidakamizwa se-hypoglycemic. Kusetshenziswa ekwelapheni zombili izinhlobo zesifo sikashukela. Umuthi uthathwa njenge-insulin onomphumela wesikhathi eside, ngakho-ke kulula ukusebenzisa.
Igama Lezwe elingafanele
INN: Insulin Glargine.
I-Tujeo isidakamizwa se-hypoglycemic. Kusetshenziswa ekwelapheni zombili izinhlobo zesifo sikashukela.
I-ATX
Ikhodi ATX A10AE04.
Khipha amafomu nokwakheka
Umuthi uyatholakala ngesimo sesisombululo esikhanyayo sokulimala kumthamo we-1.5 ml.
Into esemqoka esebenza yi-300 PIECES ye-insulin glargine. Kufakwe futhi: i-meta-cresol, i-zinc chloride, i-glycerin, i-sodium hydroxide, i-hydrochloric acid, amanzi ahlanziwe ngokukhethekile ngomjovo.
Isenzo se-Pharmacological
Kubhekiswa kuma-ejenti we-hypoglycemic. Ngenxa yomsebenzi we-insulin, izinqubo ze-metabolic ze-glucose zilawulwa. I-glucose egazini incishisiwe ngenxa yokufakwa kwayo kangcono emithanjeni yamathambo kanye nezicubu ze-adipose. Kulokhu, ukwakheka kwama-polysaccharide complexes esibindini akuvinjelwe, futhi ukwakheka kwezakhi zamaprotheni kuyanda.
Umuthi uyatholakala ngesimo sesisombululo esikhanyayo sokulimala kumthamo we-1.5 ml.
I-Pharmacokinetics
Uma kuqhathaniswa ne-insulin esebenza ngokufushane, ngemuva komjovo walesi sidakamizwa, into esebenzayo idonswa kusuka ezicutshini ezingaphansi. Ukuhlushwa okuphezulu kakhulu kwento esebenzayo egazini kuqashelwa amahora ama-2 ngemuva komjovo. It is metabolized ikakhulukazi esibindini. Kukhishwa ngendlela yama-metabolites ayisisekelo. Isigamu sempilo singamahora ayi-19.
I-insulin ende noma emfushane
Isenzo eside.
Izinkomba zokusetshenziswa
Ukusetshenziswa kwalo muthi kunconyelwa ekwelashweni kwazo zonke izinhlobo zikashukela kubantu abadala.
Ukusetshenziswa kwalo muthi kunconyelwa ekwelashweni kwazo zonke izinhlobo zikashukela kubantu abadala.
Contraindication
I-Hypersensitivity yomuntu ngamunye ezingxenyeni ngazinye zomuthi.
Ngokunakekela
Ngokuqapha, lo muthi ubekelwe abantu abanezinkinga zezinso nezinso, abahlushwa yizifo zohlelo lwezinhliziyo nabantu abadala.
Ungayithatha kanjani iTujeo?
Kuyelulekwa ukujova ngasikhathi sinye 1 ngosuku. Uma kudingeka umjovo owodwa, khona-ke imijovo ingenziwa nganoma yisiphi isikhathi sosuku. Uma kungenakwenzeka ukubeka imijovo ngasikhathi sinye, kunconywa ukwenza inqubo kungakapheli amahora ama-3 ngaphambi noma ngemuva kwesikhathi esibekiwe. Isenzo somuthi kufanele sanele usuku lonke.
Ungabala kanjani umthamo?
Ekwelapheni isifo sikashukela sohlobo 1, imijovo iyanconywa ngokudla. Kufanele kukhunjulwe ukuthi umthamo ukhethiwe esigulini ngasinye ngawodwana, kodwa akumele wedlule amayunithi ayi-100 ngosuku. Ngomphumela omuhle kakhulu, umuthi uhlanganiswa namanye ama-insulin asebenza ngokufushane.
Kuyelulekwa ukujova ngasikhathi sinye 1 ngosuku. Uma kudingeka umjovo owodwa, khona-ke imijovo ingenziwa nganoma yisiphi isikhathi sosuku.
Ukwelashwa kwesifo sikashukela sohlobo 2, umthamo wansuku zonke ungafinyelela kumayunithi angama-200. Uma isiguli singanele, singakwazi ukuhlanganiswa namanye ama-ejenti anomthelela we-hypoglycemic.
Ungayisebenzisa kanjani ipeni yesirinji?
Awukwazi ukufaka umuthi ngegazi. Lokhu kungaholela ekungcoleni kwe-insulin nezinye izidakamizwa futhi kubangele i-hypoglycemia enkulu. Imijovo yenziwa kuphela kumanoni angama-subcutaneous.
Ipeni lesirinji ligcwaliswa ngaphambili ngesisombululo futhi amayunithi angama-1 kuya kwayi-80 womuthi ayabhalwa. Ngaphezu kwalokho, ukukhuphuka akufanele kudlule iyunithi eli-1. Ipeni lesirinji eligcwalisiwe lenzelwe ngokukhethekile ukwethulwa kweToujeo SoloStar, ngakho-ke akukho sibalo sethamo esingeziwe esenziwa.
Umuthi akufanele udluliselwe epeni lesirinji uye kwesinye isirinji le-insulin. Lokhu kungaholela ekweqisweni ngokweqile. Izinaliti zomjovo ngamunye zifakwa zintsha. Kumele angabinayo inzalo.
Ngaphambi kokuqala ukusebenzisa ipeni lesirinji, udinga ukutadisha ngokucophelela imiyalo yokusebenzisa, okufanele ifakwe kwiphakheji yangempela. Ukuphepha okuthe xaxa ngomjovo akufanele kuguqule inalithi ngaso sonke isikhathi. Qiniseka ukuthi umuntu oyedwa kuphela osebenzisa isirinji.
Imiphumela emibi
Mhlawumbe ukuthuthukiswa kwe-hypoglycemia.
Engxenyeni ye-metabolism kanye nokudla okunempilo
Ukwanda okukhulu kwesifiso sokudla, isiguli sihlala sizizwa silambile. Lesi simo singakubangela ukukhuluphala. Ngenxa yokuhlakulela i-hypoglycemia, i-metabolism iyanda, okuholela ekunciphiseni koshukela wegazi ngenxa yokulimala kwe-glucose metabolism. I-carbohydrate kanye ne-fat metabolism nayo ingaphazamiseka.
Kusuka ezicutshini zemisipha
Amacala wokuthuthukiswa kwe-myalgia ayivelakancane. Ayikho idatha yomtholampilo kolunye ushintsho kwezicubu zemisipha.
Kusuka emasosheni omzimba
Ukusetshenziswa isikhathi eside kwe-insulin kuholela ekwakhekeni kwama-antibodies kuyo. Ngaphezu kwalokho, lapho usebenzisa izinhlobo ezahlukene ze-insulin, ama-antibodies akhiwa ngokulinganayo. Ukuphendula okunjalo kudinga ukulungiswa kwamthamo we-insulin.
Engxenyeni yesitho sombono
Imvamisa kukhona ukwephulwa kwe-turgor kanye ne-angle of refraction of the light by the lens. Lokhu kuholela ekuwohlokeni ku-visual acuity.
Engxenyeni yesikhumba
Ukuphendula kwasendaweni kwenzeka ezindaweni zokujova. Ubuhlungu, ukuqina, ubomvu besikhumba nokushiswa kuyaphawulwa.
Allergies
Imvamisa ukusetshenziswa kwe-insulin esebenza isikhathi eside, kuvela ukungalingani. Zibonakaliswa ngemisipha ethile yesikhumba, ukulunywa nokushiswa kwayo. I-Urticaria ne-Quincke's edema ingahle ikhule.
Imiyalo ekhethekile
Isikhathi esithathwayo sokuba izimpawu ze-hypoglycemia zikhule kuncike esikhathini sokusetshenziswa kwe-insulin kanye noshintsho kwirejimeni yokwelashwa.
Kufanele kuqashelwe ekwelashweni kweziguli lapho ukwehla kakhulu ushukela wegazi kubaluleke kakhulu emtholampilo. Lokhu kusebenza ezigulini ezinesifo sokuqina kwemithambo yegazi kanye nemithambo yokuqwasha, njengoba ubungozi bezinkinga zokuzala kanye nenhliziyo ezikhulayo ze-hypoglycemia ziyanda. Ukuqapha kufanele futhi kulandelwe ngabantu abane-retinopathy ekhulayo, okusongela ukulahleka kombono kancane kancane.
Ukuhambisana notshwala
I-Ethanol ingakhulisa futhi yenze buthaka umphumela we-hypoglycemic wokuthatha umuthi. Ngakho-ke, awukwazi ukuhlanganisa ukuthatha umuthi neziphuzo zotshwala.
Umthelela ekhonweni lokulawula izindlela
I-insulin ayithinti ijubane lokuphendula nokuqina kwe-psychomotor, ngakho-ke ukushayela okuzimele kungenzeka. Kubalulekile ukuvimbela ukuvela kwe-hypoglycemia, okuthinta impilo jikelele yesiguli.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Kuvunyelwe ukusebenzisa ngesikhathi sokukhulelwa. Ezifundweni, akubanga namiphumela emibi yezakhi ezisebenzayo zomuthi ku-fetus. Isidingo se-insulin sincipha ekuqaleni kokukhulelwa, futhi ekugcineni, ngakolunye uhlangothi, kuyanda. Ngakho-ke, ukuze uvikele ukukhula kwe-hyperglycemia, kuyadingeka ukuthi ngaso sonke isikhathi kuqashwe izinga le-glucose egazini lowesifazane okhulelwe.
Ngemuva kokubeletha ngesikhathi sokubeletha, isidingo se-insulin sincishisiwe, ngakho-ke, ukulungiswa komthamo kuyadingeka.
Ukuqokwa kukaTujeo ezinganeni
Akuvunyelwe ukuphatha izingane ngomuthi onjalo.
Sebenzisa ebudaleni
Ezigulini ezineminyaka yobudala engama-65, imithamo yokuqala nokunakekela kufanele isebenze kancane. Ingozi yokukhula kwe-hypently hypemlycemia iyanda. Ngaphezu kwalokho, okunye ukusabela kwe-hypoglycemic okuhambisana nokubanjwa njalo kwe-insulin kuvame ukuthuthuka. Ngakho-ke, ukulungiswa komthamo kufanele kwenziwe esigulini ngasinye ngamunye.
Isicelo sokusebenza kokulimala kwezinso
Kuyadingeka ukubheka njalo ukugcwala kwe-glucose kwiplasma yegazi. Umthamo we-insulin ukhethwa ngawodwa esigulini ngasinye. Ukwehluleka kwezinso, i-insulin metabolism yehlisa ijubane, futhi ngenxa yalokho isidingo somzimba sehlisiwe.
Sebenzisa umsebenzi wesibindi okhubazekile
I-metabolism yomuthi kanye nenqubo ye-gluconeogeneis kuleli cala yehla, okuholela ekuncipheni komthamo we-insulin, ngoba ushukela wegazi wehla ngokushesha okukhulu.
Ukweqisa
Izinga elikhulu le-hypoglycemia landa ngokushesha okukhulu. Ezimweni zobulukhuni obulinganiselayo, lesi simo singabhalwa ngokujwayelekile ngokuthatha inani elanele lama-carbohydrate. Ezimweni ezimbi kakhulu, lapho ikhephu likhula, isifo sokuqina okukholekayo kanye nokuphazamiseka okuthile kwemizwa, ukuhlaselwa kuyamiswa ngokufakwa kwekhambi le-dextrose noma i-glucagon.
Ukuxhumana nezinye izidakamizwa
Uma usebenzisa izidakamizwa ezithile, kungadingeka ukuthi ulungise umthamo we-insulin, ngoba amazinga eglucose wegazi angawa kakhulu, okuholela ekuthuthukisweni kwe-hypoglycemia.
Ama-Hypoglycemic agents, ama-salicylates, ama-inhibitors e-ACE, ama-antibiotic namanye ama-sulfonamides anciphisa umphumela we-hypoglycemic wale insulin. Ukulungiswa kwe-Beta-blockers ne-lithium kunganciphisa futhi kwandise umphumela wokwelapha wokuthatha i-insulin.
Ama-diuretics, i-salbutamol, i-adrenaline, i-glucagon, ama-hormone we-thyroid, ama-estrogens, amanye ama-hormone okuvimbela inzalo, i-isoniazid, ama-antipsychotic kanye nama-inhibitors e-prosthetic ngenkathi ethatha lo muthi anciphisa umphumela wawo we-hypoglycemic.
Ama-Analog
Ama-ejenti afanayo anokwakheka okufanayo nomphumela wokwelapha:
- I-Aylar;
- I-Lantus Optiset;
- ILantus SoloStar.
Izimo zeholide iTujeo evela emakhemisi
Leli thuluzi lisatshalaliswa kuphela ngumbhalo.
Ngingakwazi ukuthenga ngaphandle kadokotela?
Cha.
Intengo
Kuya ngomugqa wekhemisi nenombolo yama-cartridgeges kwiphakheji. Izindleko ezijwayelekile ngama-ruble angama-5,000. ukupakisha.
Izimo zokugcina zomuthi
Ukuvikelwa okukhulu elangeni eliqondile. Ungafriji, kepha gcina esiqandisini ngamazinga okushisa angeqi ku + 8 ° C.
Isikhathi sokuphelelwa yisikhathi
Ukufakwa okungavulwanga kugcinwa izinyanga ezingekho ngaphezulu kwe-30. Ngemuva kokusetshenziswa kokuqala, ipeni lesirinji ligcinwa isikhathi esingadluli kwezinsuku ezingama-28 ekushiseni kwegumbi.
Umkhiqizi uTujeo
Inkampani yezokukhiqiza: Sanofi Aventis Deutschland GmbH, Germany.
Ukuvikelwa okukhulu elangeni eliqondile. Ungafriji, kepha gcina esiqandisini ngamazinga okushisa angeqi ku + 8 ° C.
Ukubuyekezwa kweTujeo
Ukubuyekezwa okuningi kodokotela neziguli kulungile.
Odokotela
UMikhailov AS, i-endocrinologist, eMoscow: "Abantu abaningi manje bakhala ngokushintshwa kwalesi sidakamizwa. I-insulin uqobo ilungile, kepha kubaluleke kakhulu ukubala umthamo ngokunembile. Kulesi simo, kuzobekezelelwa kahle ngaphandle kokuvela kwezimpawu eziseceleni."
ISamoilova VV, i-endocrinologist, uNizhny Novgorod: "Umamezala wami ubephethwe yisifo sikashukela iminyaka eminingi. Mina, njengodokotela, sayidlulisa eLantus, esingasayitholi, Toujeo. Izinkomba zayo sezithuthukile. Ngingayincoma ukuthi isetshenziswe, ngoba ngizifundele mathupha imiphumela yalesi se-insulin. Ushukela ngeke "ukhule" kuwo uma umthamo ukhishwe ngokufanele. "
Isifo sikashukela
UKarina, oneminyaka engu-27 ubudala, eKiev: "Ngiyithanda kakhulu kunayo yonke insulin, ngoba igxiliwe kakhulu, futhi udinga ukuyifaka isikhathi esisodwa ngosuku. Kuyinto elula, isebenza futhi ayiphazamisi emisebenzini yansuku zonke. Ushukela ugcinwa ezingeni ngaso sonke isikhathi, azikho gxuma, hlola njalo. "
UVictor, oneminyaka engama-36, uVoronezh: "Sekuphele inyanga ngiphuza le-insulin. Ngaphambi kwalokho bekukhona nezinye izidakamizwa ezingasebenzi kahle. Ngaze ngakhohlwa nangamazwidi."
U-Andrei oneminyaka engama-44, eMoscow: "Bengihlala ngisebenzisa uLantus. Manje abambhali. Kuzofanele nginqume iToujeo, okuyinto engajabule ngayo. KuLantus, ushukela wokuzila wawusondele ku-10, manje sewu-20-25."
