Ukunquma ukuthi yikuphi okungcono - iMildronate noma iMexidol, kunconyelwa ukuthi kuhlolwe isilinganiso sokusebenza kwesidakamizwa ngasinye, okufundelwa kuyo imibono yabathengi nabachwepheshe. Lapho ukhetha, izakhiwo eziyinhloko zezidakamizwa, indlela yokusebenza, izinkomba kanye ne-contraindication iyabhekwa.
Isimilo seMildronate
Umkhiqizi - Grindeks (Latvia). Uhlobo lokukhululwa komuthi: amakhompiyutha, isixazululo somjovo (okuhloswe ngalo ukubekezela, ukujoina, umjovo we-intramuscular). Into esebenzayo yi-meldonium dihydrate. Ukuhlushwa kwayo ku-1 capsule: 250 no-500 mg. Ku-1 ml wesisombululo, umthamo wengxenye esebenzayo ngu-100 mg. IMeldonium iyi-analogue yesakhiwo sokuhlanganiswa se-gamma-butyrobetaine, esibandakanyeka kumetabolism ezingeni lamaselula.
Imisebenzi eyinhloko yesidakamizwa: i-normalization of metabolism, ikhulisa ukuqina kwezinqubo zokuhlinzekwa kwezicubu kwezicubu. Ngenxa yobukhona be-meldonium ekwakhiweni kwayo, ukwehla kokuwohloka ngokweqile komzimba kuyaphawulwa. Izimpawu zokuhlukunyezwa kwengqondo ziyaqedwa: ukungasebenzi ngokweqile, ukukhathazeka. Ngesikhathi esifanayo, umthamo wokusebenza (ngokwengqondo nangokomzimba) uyanda, kuyilapho ukukhuthazela kuyanda. Ngesikhathi sokwelashwa, kunokuthuthuka okujwayelekile esimweni somzimba, okukhona ngenxa yokwanda kokungazinzi kwama-unit we-humoral and cellular.
IMeldonium iyi-analogue yesakhiwo sokuhlanganiswa se-gamma-butyrobetaine, esibandakanyeka kumetabolism ezingeni lamaselula.
Ngaphansi kwethonya le-Mildronate, ama-acid aqukethe i-asidi aqhamuka emangqamuzaneni, izinga lokukhiqizwa kwe-carnitine liyancipha, umsebenzi we-gamma-butyrobetaine hydro oxygenase uvinjelwe. Umuthi ubuye uveze umphumela we-cardioprotective. Lokhu kungenxa yokujwayelekile kwenqubo yokulethwa komoya-mpilo kumaseli. Ngaso leso sikhathi, isilinganiso saso sokusetshenziswa siyancipha. Ngasikhathi sinye, ukusebenza kwe-myocardial kukalwa ngokujwayelekile: ngokumelene nesizinda sokuthola isifo se-ischemic, indawo yezicubu ethambekele kwi-necrosis iyancipha.
Ngenxa ye-Mildronate, ukuvuselelwa ngemuva kokukhanyiswa kwezifo zesistimu yenhliziyo kuhamba ngokushesha okukhulu. Uma kutholakala ukuhluleka kwenhliziyo, imvamisa yokuhlaselwa kwe-angina iyancipha, amandla e-myocardium enkontilekeni ayabuyiselwa.
Ngosizo lweMildronate, imiphumela yokuphazamiseka kobuchopho iyaqedwa, ngoba ngaphansi kwethonya layo ukujikeleza kwegazi ezicutshini zobuchopho kuyabonakala njengokujwayelekile. Umuthi uyasebenza ku-pathologies yemikhumbi ye-fundus, unomphumela omuhle ohlelweni lwezinzwa.
Umsebenzi wethamo lomuthi utholakala ngemuva kwemizuzu engama-60-120. Umuthi osebenzayo kanye nama-metabolites awo ayakhululwa emahoreni angama-3-6 alandelayo ngemuva kokuthatha umuthi womuthi. Izinkomba ezisetshenziswayo:
- isifo senhliziyo;
- ukwehluleka kwenhliziyo;
- i-cardiomyopathy, ethuthukiswe ngenxa yokungalingani kwe-hormonal;
- ukungasebenzi kahle kwe-cerebrovascular;
- ischemic stroke ngemuva kwengozi ye-cerebrovascular;
- ukwehla kokusebenza;
- izifo zamaphaphu
- ukuvimbela izinkinga zesifo sikashukela sohlobo 2;
- ukweqisa (izicubu zomzimba, izinzwa, ingqondo);
- ukudakwa kotshwala, kuyilapho umuthi ubekwe njengengxenye yokwelashwa okuyinkimbinkimbi, ngoba akuqedi imbangela yobuthi, kepha kunciphisa isimo, kukhuthaza ukululama.
Umuthi awunqunyelwe kwezinye izimo:
- ukusabela komzimba ngakunye kunoma iyiphi ingxenye yeMildronate;
- ukukhulelwa
- ukucaphuka
- ukwanda kwengcindezi ye-intracranial, engahle ibangelwe yizizathu ezahlukahlukene: isimila sobuchopho, ukuphazamiseka kokujikeleza kwegazi, njll.
Inkambo yokwelashwa ihlala isonto eli-1 iye ezinyangeni ezimbalwa, kuya esigabeni sokuthuthuka kwalesi sifo, ukuba khona kwezinye izinto ezingezinhle. Imiphumela emibi:
- ushintsho ekushweni kwenhliziyo;
- ukwephulwa kohlelo lokugaya ukudla, izimpawu: isicanucanu, ukushisa kwenhliziyo, ukugabha, ukubopha, ukubukeka umuzwa wokugcwala kwesisu, kungakhathalekile imvamisa yokudla kanye nosayizi wengxenye;
- ukwehlisa umfutho wegazi;
- ukukhuphuka kokukhathazeka kohlelo lwezinzwa.
Isimo seMexidol
Umkhiqizi - Farmasoft (Russia). Umuthi ungathengwa ngesimo samaphilisi, umjovo. Ukuqanjwa kufaka phakathi into esebenzayo - i-ethylmethylhydroxypyridine. Ukuhlushwa kwayo ku-1 ml yesisombululo kungama-50 mg, kwithebhulethi elilodwa lingu-125 mg. UMexidol ungoweqembu lezidakamizwa ze-antioxidant. Izakhiwo eziyinhloko:
- i-antihypoxic;
- ukuvikela ulwelwesi;
- okhathazayo;
- i-nootropic;
- anticonvulsant.
UMexidol ungoweqembu lezidakamizwa ze-antioxidant.
Umuthi uvimbela umsebenzi wama-radicals wamahhala, ukhulisa ukubekezelelana komzimba lapho kuvezwa izinto ezahlukahlukene ezingezinhle, kufaka phakathi ukushaqeka, ukushoda kwe-oxygen, ubuthi be-ethanol nezidakamizwa. UMexidol usheshisa ukululama komzimba, okuvela ngenxa yokujwayelekile kwe-metabolism. Indlela yokusebenza yayo isuselwa ekunciphiseni kwesilinganiso sokubola kwezinto ezinenzuzo ngenxa yokuvinjwa kwenqubo yemvelo ye-oxidation.
Ngaphansi kwethonya lalesi sidakamizwa, ukwephulwa kwesakhiwo se-membrane yamaseli kuyasuswa, okusiza ukubuyisela ukuhamba kwegazi endaweni ethintekile. Ngenxa yalokhu, amandla okusebenza asejwayelekile (ngokomzimba, ngokwengqondo). Kunokwanda kwekhono lokufunda lezingane. IMexidol ithinta nemingcele yegazi yokuhlwaya, ikakhulukazi, ijwayeza izinga le-cholesterol, i-lipoproteins ephansi. Ngenxa yalokhu, isisindo sincishisiwe, umsebenzi wohlelo lwezinhliziyo uyabuyiselwa.
Ngesikhathi sokwelashwa, i-metabolism in izicubu ze-myocardial ezithambekele kuyi-ischemia yenziwa yenziwa yajwayelekile. Ngaso leso sikhathi, indawo yendawo embozwe yi-necrosis iyancipha. Ukuqina kwezicubu zenhliziyo kuyabuyiselwa. IMexidol isetshenziswa ku-ophthalmology. Ngenxa yesidakamizwa, umthelela omubi kumaseli we-retina ne-opic nerve uyancishiswa ngokumelene nesizinda sokuthuthuka kwe-ischemia, ukuntuleka kwe-oksijini okungapheli.
Umsebenzi wethisthi wento eyisisekelo ufinyelelwa ngemuva kwemizuzu engama-50. Uma ufaya umuthi nge-intramuscularly, le nqubo incipha. Ngenxa yalokhu, umsebenzi omkhulu utholakala ngemuva kwamahora ama-4. Umuthi osebenzayo uMexidol wenzelwe amandla. Iyakhishwa ngesikhathi sokuchama. Ngaphezu kwalokho, ubuningi bento bususwa ngendlela efakiwe.
Leli thuluzi libekwe emacaleni amaningi, yilezi:
- i-vegetovascular dystonia;
- ingozi ye-cerebrovascular;
- i-encephalopathy;
- ukuhlaselwa okukhokhisayo;
- izinguquko ze-atherosulinotic emikhunjini yokudla okunebele;
- i-neurosis;
- ukubonakaliswa njalo kwengcindezi;
- ubuthi be-ethanol;
- ukulimala kwengqondo.
Umuthi awuvunyelwe ukusetshenziswa uma kwenzeka ku-hypersensitivity engxenyeni esebenzayo, izifo ezinzima zesibindi nezinso. Njengoba kunikezwe imininingwane enganele mayelana nethonya lemiphumela emibi yesidakamizwa emzimbeni ngesikhathi sokukhulelwa, ukunconywa kanye nasebuntwaneni, akunconywa ukuyisebenzisa.
Ngesikhathi sokulashwa, kuvela imiphumela emincane emincane: ukungezwani komzimba, umlomo owomile, isicanucanu. Ukuhambisana nezinye izidakamizwa: kukhona ukwanda kokusebenza kokusebenza kokulwa nezifo, izidakamizwa ze-anticonvulsant antiparkinsonian.
Ukuqhathanisa kweMildronate neMexidol
Izidakamizwa zikhombisa izakhiwo ezifanayo. Lokhu kuqinisekisa umphumela ofanayo ekwelashweni.
Ukufana
I-Mildronate neMexidol ayisetshenziswa ngesikhathi sokukhulelwa, ukukhipha isisu, ebuntwaneni. Izimali zikhiqizwa ngezindlela ezifanayo zokukhishwa. Izinkomba zokusetshenziswa ziyefana.
Uyini umehluko?
Ukulungiselela kuqukethe izakhi ezahlukahlukene ezisebenzayo nezisizayo. Omunye umehluko indlela ehlukile yokusebenza: I-Mildronate - i-ejenti ye-metabolic, iMexidol - i-antioxidant. Isixazululo sokuqala semishanguzo sisetshenziswa ngokungenantambo, ngokuxhunywa emzimbeni nange-parabulbarno. Umuthi uketshezi uMexidol ulawulwa ngemisipha, ngaphakathi, kuvunyelwe ukuyisebenzisa ukufaka i-dropper. Leli khambi linemiphumela emibi embalwa.
Yikuphi okushibhile?
Intengo ye-Mildronate: ama-ruble angama-300-720. kuya ngenani lomuthi. Amathebulethi ashibhile, isibonelo, iphakheji equkethe ama-40 ama-PC. angathengwa ngama-ruble angama-300. Intengo yeMexidol kumathebulethi ingama-ruble angama-400. (Izingcezu ezingama-50 iphakethe ngalinye). Izindleko zalo muthi ngesimo sesisombululo: ama-ruble angama-480-1700. Kungaphethwa ngokuthi amacwecwe weMexidol ne-Mildronate angabesigaba esifanayo samanani. Isixazululo sesibili semithi ashibhile.
Yikuphi okungcono: iMildronate noma iMexidol?
Ijubane leMexidol liphakeme. Lesi sidakamizwa sinemiphumela emibi embalwa. Mayelana nokusebenza kahle, lezi zimali ziyalingana, noma ngabe zincike ezinhlotsheni ezahlukahlukene zomsebenzi.
Uma uthathwe ngokungafanele, zombili lezi zidakamizwa zingavusa ukuhlaselwa isicanucanu.
Ukubuyekezwa kweziguli
U-Alla, oneminyaka engama-39, uBryansk
Uthathe uMexidol ngemuva kokulimala kobuhlungu ebuchosheni. Udokotela wayibeka njengengxenye yokwelapha okuyinkimbinkimbi. Wathatha omunye umuthi wobuhlungu, futhi uMexidol wasiza ukugwema ukuthuthukiswa kwezinkinga.
ULarisa, oneminyaka engama-44, uVladimir
I-Mildronate iyisidakamizwa esisindisa impilo, ngoba ngithole i-pathologies yemithambo yegazi. Ngemuva kwenkambo yokwelashwa iba lula, umphumela wezokwelapha uphikelela isikhathi eside. Imiphumela emibi ayikaze yenzeke (ngadlula ezifundweni eziningana eminyakeni emi-2 edlule).
Ukubuyekezwa kodokotela mayelana neMildronate neMexidol
Lisenkova O. A., udokotela wezifo zemizwa, oneminyaka engama-38, u-Ufa
IMildronate ibhekwa njengesidakamizwa esihle kakhulu esigabeni sayo. It ibekezelelwa kahle, isebenza kahle ekuphazamisekeni kwemisipha ehlukahlukene. Abesifazane abakhulelwe nezingane akufanele zisetshenziswe ngenxa yokushoda kobufakazi.
USmelyanets M.A., udokotela wezifo zemizwa, oneminyaka engu-35, uSamara
I-Mexicoidol ingasetshenziswa yizinhlobonhlobo zeziguli. Isebenza ngobumnene, ngaphandle kokuthi ithinta izinqubo ezihlukahlukene ze-biochemical emzimbeni. Okubi kwalesi sidakamizwa kufaka ukungasebenzi kahle okuphezulu kakhulu, yingakho ngingakuniki njengesilinganiso esizimele sokwelapha.
