Umuthi olwa nama-antidiabetesic Metformin 850 unqunyelwe uhlobo 1 nesifo sikashukela sohlobo 2. Ithuluzi lisetshenziselwa ukwelapha nokuvimbela izinkinga zalesi sifo.
Igama Lezwe elingafanele
NgesiLatin - Metforminum. INN: metformin.
I-ATX
A10BA02
Umuthi olwa nama-antidiabetesic Metformin 850 unqunyelwe uhlobo 1 nesifo sikashukela sohlobo 2.
Khipha amafomu nokwakheka
Umenzi ukhipha umuthi ngendlela yamathebulethi okusetshenziswa ngomlomo. Into esebenzayo yi-metformin enanini lama-850 mg.
Isenzo se-Pharmacological
Umuthi unomphumela we-hypoglycemic.
I-Pharmacokinetics
Imunze ngokwengxenye kusuka kwipheshana lesisu. Ukuhlushwa okuphezulu kunganqunywa ngemuva kwamahora we-1.5-2. Ukwemukelwa kukhulisa isikhathi kufike emahoreni angama-2,5. Into esebenzayo inamandla okuqongelela ezinso nasezibindini. Ukuqedwa kwesigamu sempilo kungamahora ayi-6. Ebudaleni nasekusebenzeni kweziphazamiso okungasebenzi kahle, isikhathi sokuphuma komzimba ubude sande.
Izinkomba zokusetshenziswa
Umuthi wenzelwe ekwelashweni nasekuvimbeleni isifo sikashukela sohlobo 1 nohlobo 2, kubandakanya ukukhuluphala. Isetshenziswa ihlanganiswe ne-insulin noma njengekhambi elizimele.
Umuthi wenzelwe ukukhuluphala.
Contraindication
Ithuluzi lizolimaza umzimba womuntu uma lithathwe ezimweni ezinjengokuthi:
- ukungabekezeleli izingxenye zomuthi;
- umsebenzi wezinso ongonakalisiwe;
- izifo ezinzima zesibindi;
- ukulamba kwe-oksijini komzimba, okubangelwa ukwehluleka kwenhliziyo nokuphefumula, ukufakwa kwe-myocardial infarction, i-anemia, ukujikeleza kwegazi okungekuhle;
- iminyaka yezingane ifinyelela eminyakeni eyi-10;
- ukudakwa okungapheli;
- isikhathi sokukhulelwa nokuncelisa;
- ukwephulwa kwemali esele ye-electrolyte;
- i-acid eyeqile egazini;
- i-lactic acidosis;
- ukuba khona kwezifo emzimbeni;
- ukudla okuphansi kwekhalori;
- ukukhohliseka kwezokwelapha usebenzisa i-isotopes ye-radioactive.
Ungaqali ukwelashwa ngaphambi kokuhlinzwa noma lapho kukhona ukushiswa okukhulu.
Ngokunakekela
Ukuqapha kufanele kusetshenziswe asebekhulile nasezinganeni, lapho kukhona umsebenzi onzima womzimba. Uma imvume ye-creatinine ekwehlulekeni kwezinso ingama-45-59 ml / min., Udokotela kufanele akhethe ngokucophelela umthamo.
Ungayithatha kanjani iMetformin 850
Thatha umuthi ngaphakathi ngaphandle kokuhlafuna futhi uphuze nengilazi yamanzi.
Ngaphambi noma ngemuva kokudla
Kungcono ukuthatha amaphilisi ngokudla ukuvikela imiphumela emibi emgudwini we-gastrointestinal. Kuvunyelwe ukuphuza amaphilisi ngaphambi kokudla.
Ngoshukela
Umthamo kufanele uguqulwe ngudokotela. Umthamo wokuqala wansuku zonke yi-1 ithebhulethi. Ebudaleni, akumele kuthathwe ngaphezu kwe-1000 mg ngosuku. Ngemuva kwezinsuku eziyi-10-15, ungangezela umthamo. Okuphezulu ngosuku kuvunyelwe ukuthatha i-2.55 mg. Ngohlobo 1 sikashukela, umthamo we-insulin ungancishiswa ngokuhamba kwesikhathi.
Ukwehla kwesisindo
Umuthi uhloselwe ukwehlisa isisindo ngokweqile ngemuva kwesifo sikashukela. Umthamo uncike ezingeni leshukela egazini.
Kuvunyelwe ukuphuza amaphilisi ngaphambi kokudla.
Imiphumela emibi yeMetformin 850
Ngenkathi uphuza umuthi, imiphumela emibi evela kwizitho ezahlukahlukene nezinhlelo ingahle ivele.
Amapheshana wesisu
Ukunambitheka kwensimbi emlonyeni, isifo sohudo, ukuqhakaza, isicanucanu, ukugabha, nobuhlungu esifundeni se-epigastric kungenzeka.
Ngasohlangothini lwe-metabolism
Ezimweni ezingavamile, amazinga kashukela wegazi ancipha emazingeni abucayi. Ukwehluleka ukuhambisana nomthamo kuholela ku-lactic acidosis.
Engxenyeni yesikhumba
Kuqhamuke izintokazi.
Uhlelo lwe-Endocrine
Kunokwehla kwengcindezi yegazi nokugxila kwe-glucose egazini, izinhlungu zemisipha, ukozela.
Allergies
Isikhumba kungenzeka.
Ngemuva kokuthatha iMetformin 850, ukwehla kwengcindezi yegazi kwesinye isikhathi kwenzeka.
Umthelela ekhonweni lokulawula izindlela
Uma uthatha umuthi ngokuhlangana nama-hypoglycemic agents, ubungozi bokukhula kwe-hypoglycemia buyanda. Kulokhu, kungcono ukwenqaba ukushayela izimoto nezindlela eziyinkimbinkimbi.
Imiyalo ekhethekile
Ngesikhathi sokwelashwa, kuyadingeka ukuthi uhlole ukusebenza kwesibindi, izinso nokukala ukuhlangana kweglucose egazini (ikakhulukazi lapho kuhlangene ne-insulin ne-sulfonylurea).
Ingxenye esebenzayo yesidakamizwa ilimaza ukumuncwa kuka-Vitamin B12.
Ngobuhlungu bemisipha, kuyadingeka ukuthola inqanaba le-lactic acid eplasma yegazi.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Abesifazane abakhulelwe bahlulekile ukuphuza amaphilisi. Ngaphambi kokuqala ukwelashwa, udinga ukuyeka ukuncelisa ibele.
Ukunquma iMetformin ezinganeni ezingama-850
Ingathathwa yizingane nentsha eneminyaka yobudala engama-10.
Sebenzisa ebudaleni
Sebenzisa ngokuqapha ezigulini esezikhulile.
I-Metformin 850 inqunywe ngokuqapha ezigulini esezikhulile.
Isicelo sokusebenza kokulimala kwezinso
Ngokuqapha, umuthi unqunyelwe umsebenzi wezinso ongasebenzi kahle ngokuqalwa kwe-creatinine ka-45-59 ml / min. Ezimweni ezinzima, umuthi awunqunyelwe.
Sebenzisa umsebenzi wesibindi okhubazekile
Ukwemukelwa kukhishwe ngaphandle uma kungasebenzi kahle isibindi.
I-overdose yeMetformin 850
Ukungezelela umthamo okhonjiswe kwimiyalo kuzoholela ku-lactic acidosis kanye nokuphelelwa ngamandla komzimba. Kulesi simo, isiguli siba nohudo, ubuhlungu bemisipha, ukugabha, ubuhlungu besisu kanye ne-migraine. Ukuwohloka kuholela enkomeni.
Ukuxhumana nezinye izidakamizwa
Inqubo yokwehlisa ushukela wegazi iyehla uma uthatha i-GCS, i-glucagon, ama-progestogens, ama-hormone egilo, i-thiazide diuretics, i-adrenaline, izidakamizwa ezinomphumela we-adrenomimetic, estrogens, antipsychotic (phenothiazines). Isithako esisebenzayo sinokuhambisana kabi ne-cimetidine ngenxa yokuthuthukiswa okungenzeka kwe-lactacidemia.
Ama-inhibitors e-ACE nama-monoamine oxidases, ama-sulfonylureas, ama-clofibrate, i-cyclophosphamide, i-beta-blockers, ama-NSAID angaqhakambisa umphumela we-hypoglycemic. Inhlanganisela neDanazol nama-ejenti wokuqhathanisa aqukethe iodine ayaqondiswa.
Ukwemukelwa kukhishwe ngaphandle uma kungasebenzi kahle isibindi.
Thatha ngesikhathi sokwelashwa kokuncika kotshwala, i-incl. kanye namaconsi akuvunyelwe.
Inani lempahla esebenzayo ku-plasma yegazi likhuphuka ngo-60% ngenkathi uthatha i-Triamteren, Morphine, Amiloride, Vancomycin, Quinidine, Procainamide. Umuthi we-hypoglycemic awudingi ukuhlanganiswa ne-cholestyramine.
Ukuhambisana notshwala
Ukuphuza utshwala kukhulisa ubungozi be-lactic acidosis. Kunconywa ukuthi utshwala bungabandakanywa ngesikhathi sokwelashwa.
Ama-Analog
Ekhemisi ungathola okunye esikhundleni salo muthi. Kukhona ukufana kwezinyathelo zokwenziwa kwemithi nokwakhiwa:
- Glyformin;
- I-Glucophage ne-Glucophage Long;
- Metfogamm;
- IFommetin;
- Siofor.
I-Metformin yezidakamizwa evela komunye umenzi ingaqukatha i-Zentiva, i-Long, iTeva noma iRichter kwiphakheji. Ngaphambi kokufaka esikhundleni se-analogue, udinga ukunquma izinga likashukela wegazi, uhlolwe ukuze ubekhona ezinye izifo futhi uthintane nodokotela.
Imibandela yekhefu lekhemisi
Umkhiqizo uthengiswa ngumbhedo.
Umuthi we-hypoglycemic awudingi ukuhlanganiswa ne-cholestyramine.
Ngingakwazi ukuthenga ngaphandle kadokotela
Ikhefu elingaphezu kwe-counter kungenzeka.
Malini
Intengo yokupakisha e-Ukraine ingu-120 UAH. Izindleko ezijwayelekile eRussia zingama-ruble angama-270.
Izimo zokugcina zomuthi
Amathebulethi kufanele agcinwe emazingeni okushisa aze afike ku- + 15 ° C ... + 25 ° C endaweni emnyama.
Isikhathi sokuphelelwa yisikhathi
Impilo yeshelf iyiminyaka emithathu.
Umkhiqizi
I-Farmland LLC I-Republic of Belarus.
Ukubuyekezwa mayelana neMetformin 850
Umkhiqizo ubekezelelwe kahle. Iziguli ezilandela imiyalo futhi ziqashelwa udokotela zishiya impendulo enhle. Lapho kukhona ama-contraindication, umuthi uvame ukuthathwa, kepha-ke ukubuyekezwa okungekubi kushiywe ngenxa yokwanda kwesimo.
Odokotela
U-Yuri Gnatenko, i-endocrinologist, oneminyaka engama-45, uVologda
Isakhi esisebenzayo senza ngokwejwayelekile i-carbohydrate metabolism, sikhuthaza ukusetshenziswa kwe-glucose futhi sikhulise umuzwa womzimba we-insulin. Ngokwengeziwe, udinga ukunciphisa inani lama-carbohydrate alula futhi usebenzise i-fiber ethe xaxa. Ukulandela umthamo odingekayo kanye nendlela yokuphila esebenzayo, kuzokwazi ukuvimbela izinkinga ngendlela yezifo zenhliziyo.
UMaria Rusanova, udokotela wezokwelapha, oneminyaka engama-38, Izhevsk
Ithuluzi linomphumela wokusindisa i-insulin. Umuthi usiza ukwehlisa isisindo, uthuthukise ukulawulwa kwe-glycemia. Ngokuphikisana nesizinda sokuthatha, ukuqoqwa kwesikhombi segazi le-biochemical, i-glycated hemoglobin, kuyancipha. Ukugwema imiphumela emibi evela emgodini wesisu, udinga ukwandisa umthamo 1 isikhathi emavikini ama-2 uma kunesidingo.
Iziguli
U-Elizabeth, oneminyaka engama-33, uSamara
Umuthi wokunciphisa ushukela osebenza ngempumelelo. Inikezwe ithebhulethi engu-1 kabili ngosuku. Imithamo yayanele ukwehlisa ushukela. Imiphumela emibi ifaka phakathi isiyezi, amatoho okuxekethile, isicanucanu nokuqhakaza. Ngiqale ukuthatha lo muthi ngokudla kanti nezimpawu zanyamalala. Ngincoma ukuphuza ngokuya ngemiyalo.
Ukulahlekelwa isisindo
UDiana, oneminyaka engama-29, uSuzdal
Lapho eyalelwa udokotela we-endocrinologist, waqala ukuthatha amaphilisi. Umuthi wasiza ukwehlisa isisindo, ukuguqula ushukela wegazi kanye namazinga e-cholesterol. I-Metformin ibhekane nalo msebenzi ngaphandle kwemiphumela emibi. Ezinyangeni ezintathu ngilahlekelwe ngama-7 kg. Ngihlela ukuyiqhubekisela phambili.
USvetlana, oneminyaka engama-41, eNovosibirsk
Ukusuka kuma-87 kg, wehlise isisindo saba ngu-79 ezinyangeni eziyisithupha. Thatha ukuze ungakhathazeki ngamazinga kashukela ngemuva kokudla. Ngokushesha wehla isisindo nokudla kwakhe kwehla. Esontweni lokuqala ngizwe ngicashile futhi nginesiyezi, kwenzeka ukuphazamiseka kobuthongo. Ngemuva kokunciphisa umthamo nokushintshela ekudleni okune-carb ephansi, impilo yami yathuthuka. Ngijabule ngomphumela.
