I-Bagomet - umuthi obekelwe iziguli ezinesifo sikashukela. Umuthi unezindlela eziningi zokuphikisana, ngakho-ke isetshenziswa kuphela ngokuyalelwa udokotela.
Igama Lezwe elingafanele
I-Metformin.
I-ATX
A10BA02 Metformin.
Khipha amafomu nokwakheka
Umuthi uyithebulethi ene-metformin hydrochloride (into esebenzayo) ekwakhiweni. Kunemithamo ehlukile - 1000, 850 no-500 mg. Ngaphezu kwengxenye esebenzayo, izinto eziningi ezingeziwe ezinomphumela wokwelapha zifakiwe kulo muthi. Amathebulethi ayindilinga, ahlanganiswe, futhi ifomu lezemithi elingu-850 mg yigobolondo.
IBagomet yithebhulethi ene-metformin hydrochloride ekwakhiweni kwayo.
Isenzo se-Pharmacological
Umphumela oyinhloko ohlinzekwa ngomuthi yi-hypoglycemic. Umuthi uhlose ukwehlisa amazinga kashukela egazi. Umphumela uyatholakala ngenxa yokuvinjelwa kwe-gluconeogenesis esibindini. Amathebulethi athuthukisa ukucubungula i-glucose kwezicubu futhi anciphise ukungena kwawo emgodini wokugaya ukudla.
Umuthi uhlanganisa izakhi ezinganikeli ekhiqizweni kwe-insulin futhi ezingabangeli i-hypoglycemia.
Kubantu abanesifo sikashukela kanye nesisindo somzimba esandisiwe, umuthi ukuvumela ukuthi ulahlekelwe isisindo ngokunciphisa i-hyperinsulinemia.
Uyakwazi ukwehlisa i-cholesterol yegazi.
I-Pharmacokinetics
Ngemuva kokusetshenziswa, kushesha futhi kucishe kufakwe ngokuphelele emgudwini wokugaya ukudla. Lapho kuthathwa esiswini esingenalutho, i-digestibility ingaphezu kwama-50%. Ingxenye esebenzayo ayibophele amaprotheni asatshalaliswa ku-plasma yegazi, kodwa asakazeka ngokushesha kuwo wonke izicubu zomzimba. Inamandla okuqongelela kumaseli abomvu egazi.
Ihlangabezana nemetabolism, kepha ngamaphesenti aphansi, eduze ne-zero. Kukhululwa ngokubamba iqhaza kwezinso kungashintshiwe. Lokhu kwenzeka emahoreni angama-4-6.
Umuthi uyakwazi ukwehlisa i-cholesterol yegazi.
Izinkomba zokusetshenziswa
Ibekelwe abantu abanesifo sikashukela sohlobo 2. Ukusebenza kahle kokukhuluphala okuhambisana nakho kuyaphawulwa. Kunqunywe njengendlela ye-monotherapy noma ekwelapheni inhlanganisela.
Contraindication
Awukho umuthi onqunyiwe kulezi zimo ezilandelayo:
- ukuzwela komuntu kokukodwa kokunye okuyingxenye yokwakheka;
- i-ketoacidosis yesifo sikashukela, isifo sikashukela, i-hypoglycemic coma;
- noma imuphi umsebenzi wezinso ongasebenzi kahle;
- izimo ezimbi ezisa usongo ekusebenzeni kwezinso;
- ukomisa okubangelwa isifo sohudo noma ukugabha, umkhuhlane, izifo ezibangelwa ukutheleleka;
- izimo zokubulawa yindlala komoya-mpilo (ukushaqisa, ubuthi begazi, izifo zezinso noma i-bronchopulmonary, ikoma);
- ukubonakaliswa kwezimpawu zezifo ezinamandla noma ezingalapheki ezingaba nomthelela ekwakhiweni kwezicubu ze-izicubu;
- Ukungenelela okubanzi kokuhlinzwa (kanye nokunye ukungenelela kokuhlinzwa) kanye nokulimala lapho kwenziwa i-insulin;
- ukwehluleka kwesibindi, ukungasebenzi kahle kwesibindi;
- ukudakwa okungapheli, ukudakwa ngokweqile;
- ukunamathela ekudleni okudinga ukusetshenziswa okungaphansi kuka-1000 kcal / usuku .;
- ukukhulelwa
- isikhathi sokuncelisa;
- i-lactic acidosis (kufaka phakathi umlando);
- ukuphuza iphilisi izinsuku eziningana ngaphambi nangemva kwezifundo ezibandakanya ukwethulwa kwe-ejenti ehlukile equkethe iodine.
Ungayithatha kanjani i-bagomet?
Umthamo unqunywa udokotela futhi kuncike ebufakazini, izinga loshukela egazini lesiguli. Ukwemukelwa kwenziwa ngaphakathi esiswini esingenalutho. Ukusebenzisa umuthi ngokudla kubambezela ukusebenza kwawo.
Lapho usebenzisa amaphilisi aqukethe i-500 mg, umthamo wokuqala kufanele ube ngu-1000-1500 mg. Ukugwema ukusabela okungekuhle, kunconywa ukuhlukanisa umthamo ku-doses engama-2-3. Ngemuva kwamaviki amabili ekwelashwa, kuvunyelwe ukukhulisa umthamo kancane kancane uma ukufundwa kweglucose egazini sekuthuthukile. Umthamo wansuku zonke akufanele ube ngaphezulu kuka-3000 mg.
Intsha ingathatha umthamo ka-500 mg kusihlwa ngokudla. Ngemuva kwezinsuku eziyi-10-15, umthamo kufanele ulungiswe. Ngaphezu kuka-2000 mg wesidakamizwa akufanele kudliwe ngosuku.
Ngokuphathwa kanyekanye ne-insulin, udinga ukuthatha ithebhulethi engu-1,5 r r / Usuku.
Lapho usebenzisa amaphilisi ku-850 mg, umuntu omdala kufanele athathe ithebhulethi engu-1. Umthamo ngosuku akufanele ube ngaphezulu kuka-2500 mg. Lapho uthatha amaphilisi we-1000 mg, kusetshenziswa i-1 pc. ngosuku. Umthamo omkhulu ovunyelwe yi-2000 mg. Uma ukwelashwa kwe-insulin kwenziwa ngasikhathi sinye, khona-ke umthamo onconyiwe yi-1 ithebhulethi.
Imiphumela emibi i-Bagomet
Ngomthamo ongalungile, ukusabela okungekuhle kungakhula kusuka cishe kuwo wonke amacala omzimba.
Amapheshana wesisu
Isicanucanu, ukugabha, isifiso sokudla kunganyamalala, kube nemiphumela emunyu emlonyeni.
Izimpawu ezinjalo zingasikhathaza isiguli ekuqaleni kwenkambo yokwelashwa, kepha ungadingi ukuhoxiswa kwomuthi.
Ngomthamo ongalungile, ukusabela okungekuhle kungakhula kusuka cishe kuwo wonke amacala omzimba.
Izitho zeHematopoietic
Ayikho idatha ngomthelela egazini.
Isistimu yezinzwa ephakathi
Ukukhathala, ubuthakathaka, isiyezi kuyaphawulwa.
Uhlelo lwe-Endocrine
Imiyalo ayinikezi ulwazi lokuthi umuthi uzithinta kanjani izitho zohlelo lwe-endocrine.
Ngasohlangothini lwe-metabolism
I-Lactic acidosis. Uma kwenzeka ukuphambuka, yeka ukuthatha umuthi.
Allergies
Izimbambo, ukulunywa kuyabonakala.
IBagomet ingavusa ukungezwani ngesimo ngamaphashaza, ukulunywa.
Umthelela ekhonweni lokulawula izindlela
Awukho umthelela omubi ekhonweni lokulawula izindlela, kepha imiphumela emibi efana nesiyezi kufanele icatshangwe.
Imiyalo ekhethekile
Ngesikhathi sokwelashwa, udinga ukulawula izinga le-glucose egazini esiswini esingenalutho nangemva kokudla. Uma kutholakala imiphumela emibi, thintana nodokotela ukuze uthole izeluleko. Ngokulashwa isikhathi eside, kudingeka ukugcwala kwe-plasma ye-metformin.
Sebenzisa ebudaleni
Kunqunyelwe ngokuqapha ezigulini esezikhulile esezineminyaka yobudala engama-60.
Isabelo sezingane
Kuphikiswa ezinganeni ezingaphansi kweminyaka eyi-10 ukuthatha umthamo ongaphezu kwama-500 mg. Kuze kube iminyaka engu-18, amaphilisi anomthamo ophakeme (850 no-1000 mg) awasetshenziswa.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
It is ngokuqinile umthetho.
Isicelo sokusebenza kokulimala kwezinso
Kuyavumelaniswa nokwehluleka kwezinso.
Sebenzisa umsebenzi wesibindi okhubazekile
Sebenzisa ngokuqapha uma kungasebenzi kahle isibindi.
Sebenzisa ngokuqapha uma kungasebenzi kahle isibindi.
Ukweqisa kweBagomet
I-Lactic acidosis. Izimpawu eziphambili kubuhlungu esiswini, ukungakhululeki kanye nokuqaqanjeka kwemisipha. Uma isifo sikhula, isiguli sidinga ukulaliswa esibhedlela.
Ukuxhumana nezinye izidakamizwa
Kungenzeka ukunciphisa umphumela we-hypoglycemic wesakhi esisebenzayo ngesikhathi sokusetshenziswa okufanayo ne:
- ushukela we-glucose;
- izidakamizwa eziqukethe ama-hormone;
- ama-epinephrins;
- i-glucagon;
- i-sympathomimetics;
- phenytoin;
- imithi equkethe i-phenothiazine;
- i-thiazide diuretics;
- okukhishwa okuhlukahlukene kwe-nicotinic acid;
- I-Bcc ne-isoniazid.
Umphumela wethonya le-hypoglycemic le-metformin ungaqhakanjiswa ekwelashweni okuhlangene nalokhu:
- amalungiselelo avela esulfonylurea;
- i-acarbose;
- insulin;
- Ama-NSAIDs;
- Mao inhibitors;
- oxytetracycline;
- Ama-inhibitors e-ACE;
- imithi eyenziwe nge-clofibrate;
- cyclophosphamide, β-blockers.
I-Bagomet ingathuthukiswa ngumphumela wethonya le-hypoglycemic le-metformin lapho lihlanganiswa ne-insulin.
I-Metformin inganciphisa ukumuncwa kwe-cyanocobalamin (Vitamin B12).
I-Cimetidine ibambezela isikhathi sokuqedwa kwe-metformin, okucasulayo ukuthuthukiswa kwe-lactic acidosis.
I-Nifedipine inciphisa isikhathi sokuphuma kwe-metformin.
I-Metformin inamandla okwenza buthaka imiphumela yama-anticoagulants (enziwe nge-coumarin).
Ukuhambisana notshwala
Ngesikhathi sokuphuza umuthi, kungcono ukungasebenzisi izidakamizwa eziqukethe utshwala, futhi wenqabe okwesikhashana ukuphuza utshwala.
Ama-Analog
I-Bagomet Plus - isidakamizwa esifanayo, esifana ngezinhloso nezakhiwo, kepha siqukethe i-glibenclamide. Amanye amagama womqondo ahlanganisa:
- IFommetin;
- I-Glucophage ende;
- I-Metformin;
- I-Metformin Teva;
- UGlatiniin.
Imibandela yekhefu lekhemisi
Umuthi uyabiwa lapho kwethulwa incwadi kadokotela evela kudokotela.
Ngingakwazi ukuthenga ngaphandle kadokotela?
Cha.
Izindleko
Intengo ejwayelekile ingama-ruble angama-200.
Izimo zokugcina zomuthi
Gcina endaweni eyomile, efudumele.
Isikhathi sokuphelelwa yisikhathi
Iminyaka emi-2
Umkhiqizi
UKimika Montpellier S.A.
Ukubuyekezwa kwesifo sikashukela
USvetlana, oneminyaka engama-49, uKirov: "Sekuphele isikhathi eside ngihlaselwa yisifo sikashukela. Futhi isisindo sesidlule kumakhilogremu angu-100. Udokotela wamisa umuthi, wathi ushukela osegazini uzokwehla, futhi isisindo sizophela. Izinsuku zokuqala ezimbili zokuwuphatha kabi wazizwa unobunzima. Ngemuva kwalokho umthamo wehlisiwe, ngaqala ukuzizwa kahle. Ngikudla ukudla ukuze izinga likashukela lizinze, kepha ngiyaqhubeka nokuphuza umuthi. Isisindo sihamba. Ngilahlekelwe ngama-6 kg ngenyanga eyi-1. "
UTrofim, oneminyaka engama-60, eMoscow: "Amaphilisi asanda kubekwa, intengo yafakwa, nokubuyekezwa kwaba kuhle. Ngemuva komthamo wokuqala, ngaqala ukuklebhula futhi ngapotoza isisu sami, ngavele ngageza umgudu wami wokugaya ukudla nge-ambulensi. Kwavela ukuthi benginokubekezelela ingxenye eyodwa yokusizakala, nami ngingudokotela kanye nodokotela unikeze umthamo omkhulu kakhulu. Udluliselwa komunye umuthi. "
I-Nifedipine inciphisa isikhathi sokuphuma kwe-metformin.
Ukubuyekezwa kodokotela
UMikhail, oneminyaka engama-40, uSaratov: "Umuthi unezimpawu eziningi zokuphikisana futhi uvame ukubanga imiphumela emibi, ngakho-ke ngiwubeka ngokucophelela okukhulu ezigulini, ikakhulukazi asebekhulile nezingane. Kepha labo ababekezelela kahle bazoba nomphumela omuhle. Umuthi uyasebenza. Into esemqoka ukugcina isimo ushukela wegazi, qagela ngethamo. "
ULudmila, oneminyaka engama-30 ubudala, uKursk: "Iziguli eziningi zikhononda ngokuhlukumezeka ngezinsuku zokuqala zokuphuza umuthi, ezinye zibe nemiphumela emibi. Kepha labo abaye baya kulo muthi banelisekile ngomphumela. Izinyoni ezi-2 ngetshe elilodwa ziyabulawa: ziguqula isisindo noshukela."
