I-Tozheo Solostar iyisidakamizwa esichitha isifo sikashukela esenzelwe ukuguqula amazinga kashukela egazi, sithuthukise isimo esivamile sabanesifo sikashukela, ukuvimbela ukuthuthuka okuqhubekayo kwenqubo ye-pathological futhi kuhambisane nezinkinga ezingathandeki. Isebenza njenge-analogue ye-insulin ngesenzo eside.
Igama Lezwe elingafanele
I-insulin glargine (insulin glargine).
I-ATX
Ikhodi ye-ATX yi-A10AE04.
Khipha amafomu nokwakheka
Lesi sidakamizwa sitholakala ngendlela yesisombululo esenzelwe ukujova. Uketshezi lusekuhleni futhi alunaso isithunzi esithile. Ithuluzi lithengiswa ngendlela yepeni yesirinji, okulula futhi kulula ukuyisebenzisa ngomjovo.
I-Tozheo Solostar iyatholakala ngesimo sesixazululo esenzelwe ukujova.
Isithako esisebenzayo somuthi yi-insulin glargine. Isixazululo se-Tozheo Solostar siqukethe ama-300 PIECES we-insulin glargine.
Phakathi kwezinto ezisetshenziswayo ezakha ukwakhiwa kufaka i-hydrochloric acid, glycerin, amanzi okujova, i-zinc chloride ne-cresol.
Isenzo se-Pharmacological
Ithuluzi elingelqembu le-pharmacological lezidakamizwa ezilwa nesifo sikashukela, ama-insulin asebenza isikhathi eside. Isifo sikashukela sisebenza ngobumnene ngokwedlulele nangokungatheni impilo. Lokhu kungenxa yokuthi ingxenye esebenzayo ye-insulin glargine iyafana esenzweni ne-insulin ekhiqizwa umzimba womuntu.
Ukufakwa kweTozheo Solostar kunamandla angajwayelekile okulawula izinqubo ze-glucose metabolism kanye nemetabolism.
Umuthi uqinisa ushukela wegazi, uvimbele ukuthuthukiswa kwezimpawu zokuphazamiseka kwesifo sikashukela, imiphumela emibi, inselelo ye-hypoglycemic. Lokhu kufakazelwe ngumkhuba wezokwelapha kanye nezivivinyo eziningi zemitholampilo.
Ukwelashwa nge-insulin glargine kuvuselela ukusetshenziswa koshukela yizakhi zezicubu ezingaphelele, kuvimbela izinqubo zokukhiqiza ushukela esibindini, okunikeza umphumela osheshayo wokwelapha. Ngaphezu kwalokho, lo muthi usebenza izinqubo zokwenziwa kwamaprotheni, okubalulekile ezigulini ezinesifo sikashukela okuthiwa yi-mellitus.
Uma kuqhathaniswa ne-insulin glargine emhlophe, umuthi usebenza ngempumelelo futhi uqinisekisa umphumela omude wokwelapha. Ukuphathwa kwe-subcutaneous komthamo owodwa kuyafana nokusebenzisa amayunithi ayi-100 e-insulin.
Ucwaningo olwenziwe ochwepheshe luveze ukuthi umphumela uhlala okungenani amahora angama-36 ngemuva komjovo. Umphumela we-hypoglycemic uqinisekiswa ukuphathwa kwe-subcutaneous.
I-Pharmacokinetics
Ukuhlushwa okuphezulu egazini kufinyelelwa ngemuva kwemizuzu eyi-1-15 kusukela esikhathini sokuphathwa kwe-subcutaneous. Izakhi ezisebenzayo zigcina umphumela wazo usuku noma ngaphezulu. Umzimba wesiguli udalulwa ngokwemvelo ngesibindi nangomchamo.
Ukuze ulondoloze ukugcwala okuphelele kwezinto ezisebenzayo futhi uqinisekise umphumela owelapha isikhathi eside, kwanele ukusebenzisa nsuku zonke izinsuku ezingama-3-5. Umuthi ophelele, noma ngabe uthini, ushiya emahoreni ayi-18.
Izinkomba zokusetshenziswa
Isetshenziselwa ukwelapha isifo sikashukela sohlobo 1 bese sithayipha 2 sikashukela kubantu abadala. Futhi ukuvikela i-hypoglycemia. Isetshenziselwa ukuqinisa isimo seziguli ezidinga ukuphathwa njalo kwe-insulin.
Kunganconywa phambi kwezimpawu ezilandelayo zomtholampilo:
- Ukushintshwa okubukhali kwesisindo somzimba.
- Ukulimazeka kokubonakalayo.
- Ukwanda ushukela wegazi.
- Ukoma okungapheli nokoma kwezitho zomzimba zesibeletho somlomo.
- Ubuthakathaka obujwayelekile, i-asthenia. Yehla ezinkombeni zekhono lokusebenza.
- Amabhande anekhanda.
- Ukuphazamiseka kokulala.
- Ukuqina kwengqondo ngokwengqondo.
- Ukuchama kaningi (ikakhulukazi ebusuku, okungaba ngamanga).
- Isicanucanu
- Amabhomu esiyezi.
- I-Convulsive syndrome.
- Iziqephu zenhlekelele ye-hypoglycemic.
Ukusebenzisa ithuluzi kukuvumela ukuthi umise ngokushesha izimpawu ezibuhlungu futhi uphile impilo ejwayelekile, egcwele.
Contraindication
Lomenzeli wokulwa nesifo sikashukela uyaziswa ngemiphumela yawo emincane nangobubanzi obuncane bemikhawulo engabakhona. Odokotela abakukhuthazi ukusetshenziswa kwe-Tozheo Solostar:
- nokungabekezeleli komuntu ngamunye kanye ne-hypersensitivity ezingxenyeni zemithi;
- nokuncane kwesiguli.
Ngezinye izinkinga zempilo, kufanele uthintane nodokotela wakho, ngoba iningi leminye imibango lihlobene.
Ngokunakekela
Ngokuqapha okwandayo, banikeza ikhambi labanesifo sikashukela ngokwephulwa okukhulu kwemisebenzi ye-renal ne-hepatic, ukuphazamiseka ekusebenzeni kohlelo lwe-endocrine, kanye nasebegugile (esigabeni sobudala esingaphezulu kuka-65). Ukubonisana okuphoqelekile nochwepheshe kudinga ukuthambekela kwesiguli kubonakaliso lwe-hyperglycemia, i-stenosis yemithambo ye-coronary, retinopathy ekhulayo.
Ukuqapha kunikezwe emacaleni emitholampilo alandelayo:
- ukuphazamiseka kwengqondo;
- isifo sikashukela i-mellitus eqhubeka ngendlela engapheli isikhathi eside;
- i-autonomic neuropathy;
- ukusetshenziswa kwemithi ethile.
Ukwelashwa kufanele kwenziwe ngaphansi kokuqashwa okuqinile kwezokwelapha, ngokuya ngokubhekisisa njalo kwesimo sesiguli kanye nezinye izinguquko.
Ungayithatha kanjani iTozheo Solostar
Imijovo iphathwa ngokungaziphathi. Ochwepheshe bancoma ukuthi iziguli zinake ngokukhethekile lokhu, ngoba ukuphathwa kwe-intravenous kungavusa imiphumela emibi eminingana, kuze kube senkingeni ye-hypoglycemic, iwele kobuhlungu.
Ngaphambi kokunikeza umjovo, kungcono ukufudumeza umuthi ekushiseni kwamakamelo, ngoba lokhu kuzokwenza ukuthi umjovo ungabi buhlungu.
Ikhithi ifaka ipeni lesirinji nenaliti enokulahlwa. Ithiphu kufanele isuswe kunaliti bese ifakwa isirinji ngokuqinile ngangokunokwenzeka. Ithuluzi lifakwe inzwa ekhethekile ye-elekthronikhi, ekhombisa esikrinini esincane inani lemithamo elungiselelwe. Le mpahla emangalisayo ivumela iziguli kalula futhi zimane zizibalele isilinganiso esifanele sazo ekhaya.
Isithupha sitshelwa nge-solution ye-antiseptic. Inaliti ifakwa isithupha sesandla, inkinobho yokuhambisa icindezelwa ngeminwe yesandla sesibili ukufaka imali. Ukufakwa kungenziwa esiswini, emathangeni nasehlombe. Odokotela batusa ukuthi kuguqulwe indawo yomjovo ngezikhathi ezithile, ikakhulukazi ngokusebenzisa umuthi isikhathi eside.
Umthamo ojwayelekile amayunithi angama-450. Ezimweni eziningi, ukujova kanye ngosuku kwanele. Ezimweni ezinzima, umthamo wansuku zonke ungandiswa ngezikhathi ze-2, kepha impi incishisiwe ngemuva kokuqedwa kwezimpawu ezibucayi kanye nokuqina kwesimo sesiguli.
Ukuze ulondoloze ukugcwala okungapheli kwezinto ezisebenzayo egazini, imijovo inconywa ngezikhathi ezilinganayo. Inhlanganisela yeTojeo Solostar ene-insulin ebambela amafushane iyanconywa kwiziguli ezinalolu hlobo lokuxilongwa kwesifo sikashukela esingu-1 mellitus.
Ngohlobo lwesibili lwe-mellitus yesifo sikashukela, ukwelashwa okuhlanganiswa nakho kwenziwa, kufaka phakathi ama-hypoglycemic agents enzelwe ukusetshenziswa kwangaphakathi.
Ukuze uvimbele i-hypoglycemia, umuntu kufanele abambelele ngokuqinile emthanjeni, ohlelweni lokulawulwa kwe-insulin, futhi adle njalo nangokufanele.
Imiphumela emibi ye-Tozheo Solostar
Ithuluzi lilula futhi libekezelelwa kahle. Kodwa-ke, phakathi nenkambo yokwelashwa, kunethuba lokubonakala kokuphendula okulandelayo okulandelayo:
- i-hypoglycemia;
- i-retinopathy
- ukuvuvukala kanye ne-hyperemia yesikhumba endaweni yomjovo;
- ukubonakaliswa kokungafani komzimba;
- ukungaboni kahle
- i-myalgia;
- i-lipoatrophy;
- isimo sokushaqeka;
- i-bronchospasm;
- i-hypertension ye-arterial;
- isikhumba esikhanyayo;
- imisebe njengezinkalo.
Imiphumela emibi eminingi iba yodwa ngemuva kwezinsuku ezimbalwa.
Umthelela ekhonweni lokulawula izindlela
Ukucindezelwa kohlelo lwezinzwa kanye nokwehla kwezinga lokuphendula kungenzeka ngokuqalwa kwe-hypoglycemia noma i-hyperglycemia. Ngaphezu kwalokho, ngezinye izikhathi ithuluzi liwuthinta kabi umsebenzi obonakalayo. Ngakho-ke, ukuze ugweme izingozi ezingaba khona zokulawula izindlela, ukushayela izimoto, kungcono ukwenqaba.
Imiyalo ekhethekile
Umuthi uphambaniswe ukuze usebenzise isisu esingenalutho. Amaviki ambalwa okuqala enkambo yokwelapha adinga ukubhekwa nokuqashwa njalo kwempilo yeziguli. Ukuze ugweme ukusabela okungekuhle okungatheni, kubalulekile ukulandela irekhodi lomthamo kanye nemithetho yokuphatha kwayo okungenangqondo. Ngakho-ke, ngaphambi kokuqala ukwelashwa, kufanele utadishe imiyalo ngokucophelela, uthintane nodokotela futhi uthole izeluleko eziningiliziwe zokuthi ungalwenza nini futhi kanjani umjovo.
Sebenzisa ebudaleni
Ilungele iziguli ezisesigabeni seminyaka efinyelela eminyakeni engama-75. Kodwa-ke, njengendlela yokuqapha, kubantu asebekhulile (kusuka ku-65), umuthi ubekelwe imithamo emincane futhi kunakwa ngokukhethekile ukuqapha izinkomba zeglucose yegazi.
Isabelo sezingane
Ayinqunyelwe ngenxa yokushoda kolwazi olwanele mayelana nomphumela wezinto zayo ezisebenzayo emzimbeni wezingane.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Idatha ethembekile kumthelela omubi weTojeo Solostar ekuthuthukisweni kwesibeletho kanye nenkambo yokukhulelwa ayirekhodwa. Odokotela banikeza ngokucophelela ikhambi labomama abakhulelwe kuphela uma kunezimpawu ezihlukile.
Ngesikhathi sokuncelisa, ingasetshenziswa ekwelapheni isifo sikashukela.
Ngesikhathi sokuncelisa, ingasetshenziswa ekwelapheni isifo sikashukela. Kodwa-ke, esimweni sokubonakala kwanoma yikuphi ukusabela okungafuneki enganeni, udokotela ulungisa umthamo futhi anikeze ukwelashwa okukhethekile kokudla kowesifazane.
Isicelo sokusebenza kokulimala kwezinso
Ezigulini ezinokwehluleka kwe-renal ezitholakele, isidingo se-insulin sincishisiwe, esithathwa lapho sinquma umthamo ofanele.
Sebenzisa umsebenzi wesibindi okhubazekile
Iziguli ezinenkinga yokusebenza kwe-hepatic zibonakaliswa ukuthambekisela ukunciphisa ijubane izinqubo ze-insulin metabolism ne-gluconeogenesis, ngenxa yalokho, zibekelwa imithamo ephansi.
I-overdose ye-Tozheo Solostar
I-overdose ihambisana nokukhula kwe-hypoglycemia. Izimpawu ezilandelayo zomtholampilo kufanele ziqwashise:
- coma;
- isifo esishukumisayo;
- ukuphazamiseka kwemizwa.
Ngokubonakaliswa kwezimpawu ezinjalo, isiguli sidinga ukunakekelwa kwezokwelapha okuphuthumayo.
Ukuxhumana nezinye izidakamizwa
Umphumela omuhle unikezwa ngokuhlanganiswa kweTojeo nePioglitazone. Kwenqatshelwe ngokuphelele ukuhlanganisa umuthi namanye ama-insulin aqukethe ama-insulin.
Ukuhambisana notshwala
I-Alcohol ikhulisa umphumela wezidakamizwa ze-antidiabetic futhi ingadala ukukhula kwe-hypoglycemia noma i-hyperglycemia. Ngakho-ke, ngesikhathi senkambo yokwelapha, kuyadingeka ukwenqaba ukuphuza utshwala.
Ama-Analog
Emaphuzwini ekhemisi, kufakwa ama-analogues alandelayo:
- I-Lantus.
- Tujeo.
- Solostar.
- Insulin glargine.
Emakhemisi, i-analogue yeTozheo Solosstar yi-insulin Lantus.
Imibandela yekhefu lekhemisi
Ingathengwa emakhemisi asedolobheni lapho kwethulwa incwadi kadokotela efanelekile.
Ngingakwazi ukuthenga ngaphandle kadokotela
Ungathenga umuthi ngaphandle kadokotela emakhemisi amanye online.
Intengo ye-Tozheo Solostar
Izindleko ezijwayelekile kumakhemisi cishe ama-ruble ayi-1,500.
Izimo zokugcina zomuthi
Kunconywa ukugcina endaweni emnyama, endaweni epholile, esimweni sokushisa kusuka ku-+8 kuya ku- + 12 ° С.
Isikhathi sokuphelelwa yisikhathi
Isikhathi sokugcina - izinyanga ezingama-30. Impilo yeshalofu yomkhiqizo ngemuva kokuqala kokusebenzisa ipeni lesirinji incishiswa ibe yinyanga eyodwa.
Umkhiqizi
Inkampani yaseJalimane iSanofi-Aventis Deutschland.
Impilo yeshalofu yezidakamizwa izinyanga ezingama-30. Impilo yeshalofu yomkhiqizo ngemuva kokuqala kokusebenzisa ipeni lesirinji incishiswa ibe yinyanga eyodwa.
Ukubuyekezwa kweTozheo Solostar
UNatalia, oneminyaka engama-40 ubudala, eMoscow: "Iminyaka eminingi, bahlushwa uhlobo lwesibili lwesifo sikashukela. Lapho udokotela etusa ukusetshenziswa kwe-Tozheo, kwaba ukutholakala. Umuthi kulula ukuphatha, umthamo ubalwa kalula, futhi umphumela uhlala isikhathi esingaphezu kosuku. Ngaphezu kwalokho, uheha intengo engabizi, engabizi. "
UVasily, oneminyaka engama-65, uTula: "Bathola isifo sikashukela sohlobo lwe-2. Iningi lezidakamizwa ze-hypoglycemic belingafaneleki noma belungiswa ngeminyaka. Ukuthengwa kwalo muthi kuxazululwe iningi lezinkinga zami. Umuthi usebenza ngokushesha, ubekezelelwa kahle, awubangeli miphumela emibi. Ngaphezu kwalokho, imijovo ayibuhlungu ngokuphelele futhi ayiwona umbono. ”
UValentina, oneminyaka engama-30 ubudala, eKiev: "Ngokokuqala ngqa ukuthi ngijwayele ukwazi ukuthi iTozheo Solostar eminyakeni engu-3 eyedlule. Ngabe sengikhulelwa futhi ngangifuna imishanguzo esebenza ngempumelelo nephephile yabantu abanesifo sikashukela. Lo muthi awuzange udumaze. Ngazizwa ngikhulu kakhulu. Ukukhulelwa kuhambe kahle. Ngathatha umuthi futhi ngesikhathi sokuncelisa. I-antidiabetesic enhle kamama abakhulelwe nabancelayo, abaphumelelayo nabaphephile. "
