Ukushoda kwe-insulin emzimbeni kuholela ekuphazanyisweni kokusebenza kohlelo lwe-endocrine kanye nokuthuthukiswa kwesifo sikashukela kanye ne-hypoglycemia. Ukuze ulondoloze izinga elidingekayo le-glucose egazini, iziguli zinikezwa imishanguzo, kubandakanya i-Glucobay.
Umuthi usetshenziswa njengengxenye yokwelashwa okuyinkimbinkimbi yesifo sikashukela. Ngaphambi kokusebenzisa umuthi, isiguli sinconywa ukuba sihlole uchungechunge lwezivivinyo zezokwelapha ukuze singafaki ubukhona be-contraindication nokuvimbela ukwenzeka kwemiphumela emibi.
Igama Lezwe elingafanele
I-Acarbose.
Ukuze ulondoloze izinga elidingekayo le-glucose egazini, iziguli zinikezwa imishanguzo, kubandakanya i-Glucobay.
I-ATX
A10BF01
Khipha amafomu nokwakheka
Umuthi uyatholakala ngesimo sethebhulethi ku-50 naku-100 mg. Amakhemisi kanye nezikhungo zezokwelapha zilethwa emabhokisini amakhadibhodi aqukethe amaphilisi angama-30 noma angama-120.
Imikhiqizo inombala omhlophe noma ophuzi.
Kunobungozi nokuqoshwa ezibhebheni: ilogo yenkampani ekhemisi ngakolunye uhlangothi lwezidakamizwa nezinombolo zomthamo (G 50 noma G 100) ngakolunye.
IGlucobay (ngesiLatin) ifaka:
- isithako esisebenzayo - i-acarbose;
- izithako ezingeziwe - i-MCC, isitashi sommbila, i-magnesium stearate, i-anrogenrous colloidal silicon dioxide.
Isenzo se-Pharmacological
Umuthi ohloselwe ukusetshenziswa komlomo ungoweqembu lama-hypoglycemic agents.
IGlucobay ihanjiswa ezitolo zezidakamizwa nasezikhungweni zezokwelapha emaphepheni amakhadibhodi aqukethe amaphilisi angama-30 noma ayi-120.
Ukwakheka kwamacwecwe kufaka i-acarbose pseudotetrasaccharide, evimbela isenzo se-alpha-glucosidase (i-enzyme yesisu esincane esiqhekeza i-di-, oligo- ne-polysaccharides).
Ngemuva kokuba into esebenzayo ingena emzimbeni, inqubo yokufakwa emzimbeni wama-carbohydrate ivinjelwe, ushukela ungena egazini ngamanani amancane, i-glycemia ijwayelekile.
Ngakho-ke, umuthi uvimba ukwanda kwezinga lama-monosaccharides emzimbeni, kunciphisa ingozi yokuthola isifo sikashukela, isifo senhliziyo kanye nezinye izifo zesistimu yokujikeleza kwegazi. Ngaphezu kwalokho, umuthi uthinta ukunciphisa umzimba.
Ezimweni zezokwelapha, imvamisa umuthi usebenza njengento evumayo. Umuthi usetshenziselwa ukwelashwa okuyinkimbinkimbi kohlobo 1 nohlobo 2 lwesifo sikashukela kanye nokuqedwa kwezimo zangaphambi kwesifo sikashukela.
I-Pharmacokinetics
Izinto ezakha izibhebhe zidonswa kancane kancane zivela emgudwini wesisu.
Izinto ezakha amaphilisi weGlucobai zidonswa kancane kancane zivela emgudwini we-gastrointestinal.
I-Cmax yengxenye esebenzayo egazini ibonwa ngemuva kwamahora ama-1-2 nangemva kwamahora ayi-16-24.
Umuthi wenziwa ngamakhambi, bese udlulwa yizinso futhi ngokusebenzisa inqubo yokugaya ukudla amahora angama-12-14.
Izinkomba zokusetshenziswa
Umuthi ubekelwe lokhu:
- ukwelashwa kohlobo 1 nesifo sikashukela sohlobo 2;
- ukuqeda izimo zangaphambi kwesifo sikashukela (izinguquko ekubekezelelekeni kwe-glucose, ukuphazamiseka kokuzila ukudla kwe-glycemia);
- vimbela ukukhula kwesifo sikashukela sohlobo 2 kubantu abane-prediabetes.
Ukwelapha kunikeza indlela ehlanganisiwe. Ngesikhathi sokusebenzisa umuthi, isiguli sinconywa ukuba sinamathele ekudleni okwelaphayo futhi sihole indlela yokuphila esebenzayo (ukuzivocavoca, ukuhamba nsuku zonke).
Ngesikhathi sokusebenzisa umuthi i-Glucobai, isiguli sinconywa ukuba sinamathele ekudleni okwelaphayo.
Contraindication
Kunenombolo yokuphikisana ngokusetshenziswa kwamathebulethi:
- iminyaka yezingane (kuze kube iminyaka eyi-18);
- i-hypersensitivity noma ukungabekezelelani komuntu ngamunye ezingxenyeni zomuthi;
- isikhathi sokuzala, ukukhulelwa;
- izifo ezingapheli zesisu, ezihambisana nokuphulwa kokugaya kanye nokungenisa;
- ukuqina kwesibindi;
- isifo sikashukela sikashukela;
- i-ulcerative colitis;
- stenosis yamathumbu;
- ama-hernias amakhulu;
- Isifo sikaRemkheld;
- ukwehluleka kwezinso.
Ngokunakekela
Umuthi kufanele uthathwe ngokuqapha uma:
- isiguli silimele futhi / noma sihlinzwe ukuhlinzwa;
- isiguli sitholakala ukuthi sinesifo esithathelwanayo.
Ngesikhathi sokwelashwa, kuyadingeka ukubona udokotela futhi uhlolwe njalo, ngoba okuqukethwe ama-enzyme wesibindi kungakhuphuka phakathi nezinyanga eziyisithupha zokuqala.
Ungayithatha kanjani iGlucobay
Ngoshukela
Ngaphambi kokudla, umuthi udliwa uphelele, ugezwe ngamanzi ngamanani amancane. Ngesikhathi sokudla - ngefomu elichobozekile, nengxenye yokuqala yesitsha.
Umthamo ukhethwa nguchwepheshe wezokwelapha ngokuya ngezimpawu zomzimba wesiguli ngamunye.
Ukwelashwa okunconyelwe iziguli ezinesifo sikashukela kungokulandelayo:
- ekuqaleni kokwelashwa - 50 mg izikhathi ezi-3 ngosuku;
- isilinganiso somuthi wansuku zonke singama-100 mg kathathu ngosuku;
- Umthamo ofanele ovunyelwe - 200 mg izikhathi ezi-3 ngosuku.
Umthamo uyanda ngokungabikho komtholampilo emavikini ama-4-8 ngemuva kokuqala kokwelashwa.
Uma, kulandela ukudla nezinye izincomo zikadokotela oholayo, isiguli sikhuphule ukwakheka kwegesi nohudo, ukwanda komthamo akwamukeleki.
Ngaphambi kokudla, umuthi iGlucobai udliwa uphelele, ugezwe ngamanzi ngamanani amancane.
Ukuvimbela uhlobo 2 lwesifo sikashukela, inqubo yokusebenzisa umuthi ihlukile kancane:
- ekuqaleni kokwelashwa - 50 mg 1 isikhathi ngosuku;
- isilinganiso sokwelapha esivamile singama-100 mg kathathu ngosuku.
Umthamo wanda kancane kancane ngaphezulu kwezinsuku ezingama-90.
Uma imenyu yesiguli ingenayo ama-carbohydrate, ungangeqa ukuphuza amaphilisi. Endabeni yokudla i-fructose ne-glucose emsulwa, ukusebenza kwe-acrobase kuncishiswa kube yi-zero.
Ukwehla kwesisindo
Ezinye iziguli zisebenzisa umuthi ekubuzweni ukuze unciphise isisindo. Kodwa-ke, ukusetshenziswa kwanoma yisiphi isidakamizwa kumele kuvunyelwane nodokotela oholayo.
Ukunciphisa isisindo somzimba, amaphilisi (50 mg) athathwa isikhathi esingu-1 ngosuku. Uma umuntu enesisindo esingaphezu kwama-60 kg, umthamo unyuswa amahlandla ama-2.
Ezinye iziguli zisebenzisa umuthi i-Glucobay ukunciphisa umzimba.
Imiphumela emibi ye-Glucobay
Amapheshana wesisu
Ngesikhathi sokwelashwa, kwezinye izimo, iziguli zinemiphumela emibi:
- isifo sohudo
- ukuthopha;
- ubuhlungu esifundeni se-epigastric;
- isicanucanu
Allergies
Phakathi kokunye okungahambi kahle kuyatholakala (kuyaqabukela):
- ukushesha ku-epidermis;
- exanthema;
- i-urticaria;
- I-edema kaQuincke;
- ukugcwala kwemithambo yegazi yesitho noma ingxenye yomzimba enegazi.
Kwezinye izimo, ukuqina kwama-enzyme wesibindi kuyanda ezigulini, kuvela i-jaundice, futhi i-hepatitis iyakhula (kuyaqabukela).
Umthelela ekhonweni lokulawula izindlela
Ukusetshenziswa kwomuthi akuthinti amandla okushayela izimoto ngokuzimela. Kodwa-ke, ngokuvela njalo kwemiphumela emibi (isicanucanu, uhudo, izinhlungu) ngesikhathi sokwelashwa, kufanele uyeke ukushayela.
Imiyalo ekhethekile
Sebenzisa ebudaleni
Ngokusho kwemiyalo yokusebenzisa, ngaphandle kokunciphisa noma ukwandisa umthamo.
Kunquma uGlucobaya ezinganeni
Kuqinisekisiwe.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Kuvinjelwe.
Isicelo sokusebenza kokulimala kwezinso
Ukushintsha umthamo akudingekile.
Sebenzisa umsebenzi wesibindi okhubazekile
Kuphikisiwe uma isiguli sitholwa sinehluleki kakhulu lwezinso.
I-Glucobay overdose
Lapho usebenzisa imithamo ephezulu yemithi, kuqubuka uhudo kanye ne-flatulence, kanye nokwehla kwesibalo seplanethi.
Kwezinye izimo, iziguli ziba nesicanucanu nokuvuvukala.
I-overdose ingenzeka uma usebenzisa amaphilisi ngokuhlangana neziphuzo noma imikhiqizo equkethe inani elikhulu lama-carbohydrate.
Ukuqeda lezi zimpawu okwesikhashana (amahora angu-4-6), kufanele wenqabe ukudla.
I-overdose ingenzeka uma usebenzisa amaphilisi ngokuhlangana neziphuzo noma imikhiqizo equkethe inani elikhulu lama-carbohydrate.
Ukuxhumana nezinye izidakamizwa
Umphumela we-hypoglycemic wesidakamizwa okukhulunywa ngaso uvuselelwa yi-insulin, metformin ne-sulfonylurea.
Ukusebenza kokwelashwa kuncishiswa ngokusetshenziswa kanyekanye kwe-acrobase nge:
- i-nicotinic acid nemithi yokuvimbela inzalo yomlomo;
- ama-estrogens;
- glucocorticosteroids;
- ama-hormone egilo;
- i-thiazide diuretics;
- i-phenytoin ne-phenothiazine.
Ukuhambisana notshwala
Uphuzo oludakayo lukhulisa ushukela wegazi, ngakho-ke ukuphuza utshwala ngesikhathi sokwelashwa kuyahlukaniswa.
Uphuzo oludakayo lukhulisa ushukela wegazi, ngakho-ke ukuphuza utshwala ngesikhathi sokwelashwa kuyahlukaniswa.
Ama-Analog
Phakathi kwezidakamizwa ezifanayo esenzweni yemithi, okulandelayo kuyaphawulwa:
- Alumina
- Siofor;
- I-Acarbose.
Imibandela yekhefu lekhemisi
Amaphilisi kadokotela.
Ngingakwazi ukuthenga ngaphandle kadokotela
Kunamacala okuthengiswa kwalo muthi ngaphandle kwezitifiketi zikadokotela. Kodwa-ke, ukwelashwa ngokwakho kuyimbangela yemiphumela emibi engenakuphikwa.
Intengo yeGlucobay
Izindleko zamathebhulethi (50 mg) ziyehluka kusuka kuma-ruble angama-360 kuya kwangama-600 kwezingcezu ezingama-30 iphakethe ngalinye.
Phakathi kwezidakamizwa ezifanayo esenzweni samakhemikhali, kubalwa uSiofor.
Izimo zokugcina zomuthi
Amacwecwe anconyelwa ukuba agcinwe kwikhabethe noma kwenye indawo emnyama, emazingeni okushisa angadluli + 30 ° ะก.
Isikhathi sokuphelelwa yisikhathi
Iminyaka engu-5 kusukela ngosuku lokukhululwa.
Umkhiqizi
IBAYER SCHERING PHARMA AG (Germany).
Ukubuyekezwa mayelana neGlucobay
Odokotela
UMikhail, oneminyaka engama-42 ubudala, uNorilsk
Umuthi uyithuluzi elisebenzayo ekwelapheni okuyinkimbinkimbi. Zonke iziguli kufanele zikhumbule ukuthi umuthi awukunciphisi isifiso sokudla, ngakho-ke ngesikhathi sokwelashwa kubalulekile ukulawula isisindo, ukunamathela ekudleni nasekuzivocavoca.
Ngesikhathi sokulashwa nge-Glucobai, odokotela batusa ukuhola indlela yokuphila esebenzayo (ukuzivocavoca, ukuhamba nsuku zonke).
Isifo sikashukela
U-Elena, oneminyaka engama-52 ubudala, eSt
Ngoshukela wohlobo 2, ngikhuluphele. Njengoba kuchazwe udokotela we-endocrinologist, waqala ukuphuza umuthi ngohlelo olukhulayo, oluhambisana nokwelashwa kokudla. Ngemuva kwezinyanga ezimbili zokwelashwa, wakhipha amanye ama-5 kg, ngenkathi izinga likashukela egazini lincipha. Manje ngiyaqhubeka nokusebenzisa umuthi.
UmRoma, oneminyaka engama-40 ubudala, u-Irkutsk
Ngishiya isibuyekezo kulabo abangabaza ukusebenza kahle kwalo muthi. Ngiqale ukuthatha i-acrobase ezinyangeni ezi-3 ezedlule. Umthamo wanda kancane kancane, ngokuya ngemiyalo. Manje ngithatha i-1 pc (100 mg) izikhathi ezi-3 ngosuku, kuphela ngaphambi kokudla. Kanye nalokhu, ngisebenzisa ithebhulethi eyi-1 yeNovonorm (4 mg) kanye ngosuku. Le ndlela yokwelashwa ikuvumela ukuthi udle ngokuphelele futhi ulawule izinga lakho le-glucose. Isikhathi eside, izinkomba ezedivayisini azidluli ngo-7.5 mmol / L.
Ukulahlekelwa isisindo
U-Olga, oneminyaka engama-35, uKolomna
Umuthi usetshenziselwa ukwelapha isifo sikashukela, kepha hhayi ukunciphisa isisindo somzimba. Ngeluleka iziguli ukuthi ziphuze umuthi kuphela njengoba kuchazwe udokotela oholayo, futhi kungcono ukuthi abantu abaphilile bawushiye umqondo wokunciphisa umzimba ngokusebenzisa i-chemistry. Umngani (hhayi onesifo sikashukela) ekutholeni i-acrobase ubonakale ethuthumela okukhulu futhi ukugayeka kwaphulwa.
USergey, oneminyaka engama-38, uKhimki
Umuthi uvimba ukumuncwa kwama-kilojoule angena emzimbeni ngokusetshenziswa kwama-carbohydrate ayinkimbinkimbi, ngakho-ke ithuluzi lisiza ukwehlisa isisindo. Umlingani izinyanga ezintathu zokusebenzisa i-acrobase ususe amanye amakhilogremu ayi-15. Ngasikhathi sinye, wanamathela ekudleni futhi wadla kuphela ukudla kwekhwalithi ephezulu nokunempilo. Ubengenayo imiphumela emibi. Kepha uma ukholelwa ukubuyekezwa, ukondleka okungafanele ngenkathi uthatha amaphilisi kukuthinta kabi ukusebenza kanye nokubekezelela kwomuthi.
