I-Amoxicillin powder: Imiyalo esetshenzisiwe

I-Amoxicillin inomphumela omuhle we-bactericidal. Kusetshenziswa ekwelapheni izifo. I-Amoxicillin powder yenzelwe ukumiswa. Kwesinye isikhathi iziguli zibiza izinhlobo ezingezona zomuthi (ukumiswa okungenzekanga akwenziwa).

Amafomu akhona akhishwe kanye nokwakheka

Kunezindlela eziningi eziphambili:

• i-powder yokumiswa;
• amaphilisi
• iziganu;
• amaphilisi.

I-Amoxicillin inomphumela omuhle we-bactericidal. Kusetshenziswa ekwelapheni izifo.

I-powder yenzelwe ukulungiselela ukumiswa okhethekile. Lokhu kungaba umjovo noma indlela yokufaka yokuphatha.

I-powder inombala omhlophe, i-tint yayo ephuzi ivunyelwe. Izinto ezisebenzayo yi-amoxicillin sodium ne-clavulanic acid. I-Powder ingaqukatha i-0.5 noma i-1.0 g ye-amooticillin ne-0,0-0.2 g ye-asidi.

Kutholakala emabhodleleni enziwe ngezinto zokuvikela i-polymer. Ibhokisi lekhadibhodi liqukethe ibhodlela eli-1 nemiyalo esetshenzisiwe. Ukupakisha kufaka amabhodlela ayi-10.

Igama Lezwe elingafanele

INN: Amoxicillin.

I-ATX

Ikhodi ye-ATX: J01CR02.

Isenzo se-Pharmacological

Umuthi ungowezidakamizwa ze-antibacterial zochungechunge lwe-penicillin. Ingxube ekhethekile yama-penicillin nama-beta-lactamase inhibitors. Umphumela utholakala ngenxa yokuhlanganiswa kwezinto ezisebenzayo: i-clavulanic acid ne-amoxicillin.

I-powder yenzelwe ukulungiselela ukumiswa okhethekile.

Umuthi ungowezidakamizwa ze-antibacterial zochungechunge lwe-penicillin.

Umphumela wesidakamizwa utholakala ngenxa yokuhlanganiswa kwezinto ezisebenzayo: clavulanic acid ne-amoxicillin.

Umphumela we-bactericidal utholakala ngokuvimbela ukuvela okusheshayo kwezindonga zamagciwane we-pathogenic.

Kukhombisa ukusebenza kahle maqondana nama-microorganisms we-aerobic gram-negative ne-gram-positive, kuma-anaerobes amaningi.

I-Clavulanic acid ivimbela ngokushesha ukwakheka kwama-beta-lactamases athile. Unokuphakama okukhulu kwama-penicillinases.

I-Pharmacokinetics

Zombili izinhlanganisela ezisebenzayo zidonswa ngokushesha futhi zisatshalaliswa kahle kuwo wonke izicubu nezitho zomzimba. I-Amoxicillin ingatholakala kuketshezi lwe-synovial, izicubu zomsipha, i-gallder yesibindi, isibindi kanye ne-Prostate gland. I-Clavulanic acid ingena emaphashini, uketshezi lwe-pleural, endlebeni ephakathi, ngaphezu kwalokho, ingene esibelethweni nakwizithasiselo zalo.

I-Bioavailability nokubopha ezinhlakeni zamaprotheni kuphansi. Yenzelwe ikakhulukazi esibindini. Isigamu sempilo singamahora amabili. Ukuhlungwa kwe-plasma okuphezulu kufinyelelwa emizuzwini embalwa ngemuva kokuthi umuthi ungene egazini.

Igcotshwa ngemuva kokucolisiswa kobuso bezinso ngezinso ngendlela ecishe ingashintshiwe nangendlela yama-metabolites e-clavulanic acid. Kukhishwe ngokuphelele emahoreni ayi-6 ngemuva kokuphathwa. Inani elikhulu lezinto ezisetshenzisiwe zihanjiswa izinso, kepha ezinye zingakhishwa ngamaphaphu namathumbu. Lokhu kufakazelwa ukuhlolwa komchamo.

Yini esiza i-amooticillin

Isetshenziselwa ukwelapha izifo ezithathelwanayo nezivuvukayo ezikhula ngenxa yemiphumela eqondile yamabhaktheriya we-pathogenic abhekene nezidakamizwa.

Izinkomba zokusetshenziswa kwe-Amoxicillin yizifo zomgudu ophakeme wokuphefumula, isibonelo, i-sinusitis.

Umuthi uboniswa ukutheleleka kwezitho zangaphansi zokuphefumula, isibonelo, ne-bronchitis.

I-Amoxicillin ibekelwe ukwelashwa kwezifo zohlelo lwezitho zofuzo, ngokwesibonelo, i-cystitis.

Izinkomba zokusetshenziswa kwalesi sidakamizwa yizifo ezingama-gynecological, ngokwesibonelo, i-vaginitis.

Ngohlobo 2 lwesifo sikashukela, umuthi olwa namagciwane ungasetshenziswa, ngoba akukho glucose ekwakhiweni kwalo.

Ngesikhathi sokwelashwa kwesifo sikashukela, kuyadingeka ukuthi kwenziwe izivivinyo ukuthola izinguquko ekuhlushweni kwe-glucose egazini.

Izinkomba eziphambili ezisetshenziswayo:

• izifo zephepha eliphakeme lokuphefumula - i-sinusitis, i-otitis media, i-tonsillitis, i-pharyngitis;
• ukutheleleka kwezitho zokuphefumula eziphansi - i-bronchitis, pneumonia;
• izifo zohlelo lwe-genitourinary - pyelonephritis, cystitis, prostatitis, urethritis, gonorrhea;
• isifo sofuba
• izifo ze-gynecological - i-salpingitis, i-cervicitis, i-endometritis, i-vaginitis;
• izilonda ezithathelwanayo zesikhumba nezicubu ezithambile - impetigo, erysipelas, abscess, phlegmon, dermatoses ahlukahlukene kanye leptospirosis;
• izinqubo zokutheleleka ezithweni ezixhumene namathambo;
• izilonda zepheshana elihlanganisiwe - cholangitis, cholecystitis;
• ukutheleleka okuqala emva kokungenelela kokuhlinzwa.

Ngoshukela

Kuhlobo lwesifo sikashukela sohlobo 2, i-antibiotic ingasetshenziswa. Alinawo ushukela. Kepha ngesikhathi sokwelashwa, kuyadingeka ukuthi kwenziwe izivivinyo ukuthola izinguquko ekuhlushweni kwe-glucose egazini. Umthamo ubekelwe ukuba omncane ukuze uvikele ukuthuthukiswa kokungaphenduki okuhle.

Contraindication

Kukhona izimo zokugula lapho ukusetshenziswa kwenqatshelwe:

• i-hypersensitivity yezakhi ezibulala amagciwane;
• ukungabekezelelani komuntu ngamunye kuma-cephalosporins;
• ukwephulwa okuqhubekayo kokusebenza kwesibindi okujwayelekile;
• i-jaundice evimbayo, engaqala ukusetshenziswa kwalo muthi;
• mononucleosis esithathelwanayo.

Ukuphazamiseka okuqhubekayo ekusebenzeni okujwayelekile kwesibindi kungukuphikisana nokusetshenziswa kwe-Amoxicillin.

Ukwehliswa kokuthatha umuthi nakho ku-mononucleosis ethelelekayo.

Lapho usebenzisa i-Amoxicillin, i-jaundice engavinjelwa ingahle ikhule.

Ungayithatha kanjani i-Amoxicillin

Ukulungiselela izixazululo zomjovo we-intravenous, okuqukethwe kwe-vial kuchithwa ku-10 noma 20 ml wamanzi wokujova. Kuya ngomthamo wezingxenye ezikhona ku-powder. Umuthi uphathwa ngaphakathi, kancane. Inqubo ithatha imizuzu emi-3.

Ukulungiselela isixazululo sokufakwa kwe-intravenous, i-powder ihlanjululwe ngo-50 noma 100 ml we-infusion solution. Isikhathi sokumiliselwa kufanele sithathe okungenani isigamu sehora.

Abantu abadala nezingane ngemuva kweminyaka engu-12 ubudala banikezwa imishanguzo kumthamo wayo osebenzayo njalo emahoreni ayi-8. Uma ukutheleleka kukhulu kakhulu, isikhathi phakathi kwemijovo singancishiswa saba amahora angama-6. Umthamo omkhulu wabantu abadala akufanele udlule ku-6 g we-powder ngosuku.

Kumntwana ongaphansi kweminyaka engu-12 yobudala, umthamo ukhethiwe ngokuhlukile ngokuhambisana nesisindo somzimba. Ukuvunyelwa okuphezulu akuyona ngaphezu kwe-250 mg lapho uthatha umuthi ngaphakathi kwifomu lethebhulethi.

Ngaphambi noma ngemuva kokudla

Ukudla cishe akuchaphazeli ukumunyisa umuthi. Uma udla ukudla okunamafutha amaningi, ukumuncwa kwehlisa kancane.

Umthamo omkhulu wabantu abadala akufanele udlule ku-6 g we-powder ngosuku.

Kumntwana ongaphansi kweminyaka engu-12 yobudala, umthamo ukhethiwe ngokuhlukile ngokuhambisana nesisindo somzimba.

Lapho udla ukudla okunamafutha amaningi, ukumuncwa kwalesi sidakamizwa kwehlisa kancane.

Zingaki izinsuku zokuphuza

Ukwelashwa kwenziwa izinsuku ezingekho ngaphezulu kwezingu-14 ngaphandle kokubheka kabusha isimo sesiguli. Isikhathi sizoncika eminyakeni yobudala nesisindo, isimo sezinso.

Imiphumela emibi ye-Amoxicillin

Lapho uthatha i-antibiotic, kusabela okuhlukahlukene okuhlukahlukene. Zingathinta zonke izitho nezinhlelo.

Amapheshana wesisu

Kusukela kwipheshana lesisu, izinguquko ze-dyspeptic ziyabhekwa. Ukucanuzelelwa okukhulu kanye nokuhlanza, kuvela isifo sohudo. Ngokuvamile i-colitis iba.

Isistimu yezinzwa ephakathi

Isiyezi esinzima nobuhlungu bekhanda obuqhubekayo buyaqapheleka. Mhlawumbe ukuthuthukiswa kwe-convulsive syndrome. Paresthesia kanye nokuthuthumela kuyabonakala.

Kusuka ohlelweni lokuphefumula

Ubunzima bokuphefumula. Lokhu kwenzeka ngenxa yemikhaba yezikhungo zokuphefumula esimweni sokukhula kwe-edema yeQuincke noma ngokwethuka kwe-anaphylactic.

Kusuka ohlelweni lwezinhliziyo

Akuvamile ukubonwa. Zibonakalisa ushintsho olukhulu ekucindezelweni kwegazi, yize i-tachycardia ne-arrhasmia kwenzeka kaningi.

Njengomphumela oseceleni wokuthatha umuthi emgudwini wesisu, ushintsho lwe-dyspeptic luyabonakala.

Ngokuvamile i-colitis iba.

Isiyezi esinzima nobuhlungu bekhanda obuqhubekayo buyaqapheleka.

Imvamisa, ngenkathi uphuza umuthi, i-tachycardia ne-arrhasmia kwenzeka.

Allergies

Kujwayelekile. Ngokungabekezeleli, i-angioedema ingakheka. Ukuqhuma kwesikhumba kuvela ukuthi kuyabukeka kakhulu. Kuthuthukisa i-erythema multiforme, urticaria. I-allergic vasculitis iye yabikwa.

Ngaphezu kwalokho, izinso nazo ziyahlupheka. I-Crystalluria nephritis kuyabonakala. Engxenyeni yezinso, kungenzeka i-jaundice ne-hepatitis evimbayo.

Imiyalo ekhethekile

Ngaphambi kokuqala, udinga ukuqoqa ama-anamnesis futhi uthole ukuthi ngabe kukhona yini ukungaphenduki komzimba kuma-antibiotics. Awukwazi ukunquma umuthi uma kukhona izinsolo zokuthi une-mononucleosis ethelelekile.

Ngokunakekelwa okukhulu, umuthi uyasetshenziswa uma kwenzeka kwenzeka nge-pathologies yezinso nesibindi.

Ungazinikeza kanjani izingane

Umuthi uvame ukusetshenziswa ebuntwaneni. Umthamo ubalwa ngokuya ngesisindo sesiguli esincane. Uma kunesidingo, umthamo ungancishiswa uye kusebenza okungenani.

Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba

Kwenqatshelwe ukuthatha i-antibiotic ngesikhathi sokuzala kwengane nangesikhathi sokuzala.

Izinto ezisebenzayo zingena kahle ngokusebenzisa isithiyo esivikela i-placenta futhi zibe nomthelela we-teratogenic ne-embyogenic kwi-fetus.

Kulokhu, kukhiqizwa izinto ezingejwayelekile zokuthuthukiswa kwe-intrauterine kwesibeletho.

Izithako nazo zidlulela obisini lwebele. Uma ukwelashwa kudingekile, udinga ukuyeka ukuncelisa ngalesi sikhathi.

I-Synergism yenzeka ngokusetshenziswa kanyekanye kwe-Amoxicillin neRifampicin.

Lapho uthatha i-Amoxicillin, umsebenzi cishe wawo wonke izindlela zokuvimbela inzalo uyancipha.

Ngokusebenzisa okuhlanganisiwe nge-methotrexate, ubuthi bamuva buyanda.

Ukweqisa

Uma kwenzeka kweqa ngokweqile ingozi, izimpawu ezingathandeki ze-dyspeptic zingavela, ngaphezu kwalokho, ukuphazamiseka ebhalweni le-electrolyte yamanzi. I-Crystalluria ihlala ikhula, okuholela ekubukekeni kwehluleki kwe-renal.

Ukwelapha kuleli cala kuwuphawu kuphela. Ukwelashwa kwe-detoxification nokulungiswa kwesilinganiso esidingekayo se-electrolyte. Inqubo ye-hemodialysis izosiza ukususa ngokuphelele ubuthi.

Ukuxhumana nezinye izidakamizwa

I-Synergism yenzeka ngokusetshenziswa kanyekanye ngama-bactericidal bacteria. Lokhu kufaka i-aminoglycosides, clavulanates we potassium, cephalosporins kanye rifampicin. Ama-Macrolides, ama-lincosamines, ama-sulfonamides kanye nama-tetracyclines anethonya lokuphikisana.

Ukusebenza kwe-anticoagulants engaqondile kukhuphuka ngokucindezela i-microflora yamathumbu kanye nokuhlanganiswa kwe-Vitamin K.

Umsebenzi cishe wazo zonke izindlela zokuvimbela umlomo uyancipha.

Ama-diuretics, izidakamizwa ezingezona ze-steroidal ezilwa nokuvuvukala nama-blockular secretion blockers akhulisa ukuhlangana kwezinto ezisebenzayo emchazweni nasegazini.

Ngokusebenzisa okuhlanganisiwe nge-methotrexate, ubuthi bamuva buyanda.

Ngokwezemithi, umuthi awuhambisani ne-aminoglycosides. Ekwelapheni isifo sofuba, ukuxilongwa kwe-Mantoux kufanele kwenziwe ngezikhathi ezithile.

Ukuhambisana notshwala

Ungahlanganisi notshwala. Lokhu kuzonciphisa ukumuncwa futhi kunciphise ukusebenza kahle, kube nomthelela ekwandeni kwezimpawu zokudakwa kanye nomonakalo ohlelweni lwezinzwa oluphakathi.

Ama-Analog

Kunezindlela eziningi zomuthi:

• U-Amosin;
• I-Ecobol;
• I-Amoxicar;
• Flemoxin Solutab;
• I-Amoxiclav;
• Carbapenemam.

Imibandela yekhefu lekhemisi

Ungathenga umuthi ezitolo zezidakamizwa kuphela ngemuva kokunikeza incwadi kadokotela ekhethekile.

Intengo

Izindleko zomuthi zizoncika kunani lamabhodlela asemaphaketheni nakuwo umuthi wasokhemisi. Ngokwesilinganiso, intengo isuka kuma-ruble ayi-140.

Izimo zokugcina zomuthi

Ungasigcina lesi sidakamizwa ngamazinga okushisa angadluli ku-15 ° C. Vikela elangeni. Gwema kude nezingane.

Isikhathi sokuphelelwa yisikhathi

Iminyaka emi-2 ukusuka ngelanga lokwenziwa ngalo umuthi, okufanele likhonjiswe kwiphakheji yoqobo.

I-Amoxiclav iyi-analogue yesidakamizwa i-Amoxicillin.

Umkhiqizi

Inkampani ekhiqiza: OJSC "Krasfarma" Russia.

Ukubuyekezwa

U-Alexandra, oneminyaka engama-32, uPenza: "Ngu-Amoxicillin kuphela owasiza ekulweni ne-bronchitis engapheli. Ngazizwa ngomphumela wethonsi ngosuku olulandelayo. Angizwanga nakancane ukusabela okungekuhle kimi. Ngazicekela phansi ama-10."

USemen, oneminyaka engu-40 ubudala, uTula: "Banginikeza umuthi wokwelapha inyumoniya. Kodwa angikwazanga ukumelana nokwehla. Ukuqedwa kwesifo sohudo kwaqala, kwaqubuka umqubuko omkhulu esikhunjeni sami. I-edema kaQuincke yathuthukiswa kamuva. I-antibiotic yathathelwa indawo ngomunye."

U-Ludmila, oneminyaka engu-27, eMoscow: "Ngisanda kuba nabezindaba ezibalulekile kakhulu ze-otitis. Sincome abantu abashiya phansi nge-Amoxicillin. Ngiwuzwe umnyakazo ngaso leso sikhathi. Abadonselayo abaze balethe kubi.