Amafutha e-Ofloxacin: Imiyalo esetshenzisiwe

Amafutha e-Ofloxacin abonakala ngemiphumela ehlukahlukene ye-antibacterial. Kusetshenziswa ku-ophthalmology ukwelapha izilonda ezithathelwanayo. Leli yi-antibiotic enamandla ngokuqinile, ngakho-ke yisebenzise ngokuqapha.

Igama Lezwe elingafanele

Isidakamizwa se-INN - i-Ofloxacin.

I-ATX

Uwoyela ungowamaqembu ama-quinolones futhi unekhodi ye-ATX S01AE01.

Amafutha e-Ofloxacin abonakala ngemiphumela ehlukahlukene ye-antibacterial.

Ukwakheka

Ingxenye esebenzayo yamafutha yi -loloacacin. Ku-1 g yesidakamizwa, okuqukethwe kuyo kungama-3 mg. Ukwakheka okusizayo kumelelwa yi-propyl paraben, i-methyl parahydroxybenzoate ne-petrolatum.

Uwoyela uhambisana ngendlela efanayo futhi umhlophe noma uphuzi ngombala. Kukhiqizwa kumashubhu ama-3 noma ama-5 g .. Ukufakwa kwangaphandle kuyikhadibhodi. Umyalo unamathiselwe.

Amafutha e-Ofloxacin akhiqizwa kumashubhu ama-3 noma ama-5 g, okufakiwe kwangaphandle kuyikhadibhodi.

Isenzo se-Pharmacological

I-compound eyisebenzayo ye -loxacin iyigciwane le-fluoroquinolone lesizukulwane sesibili. Le nto ivimbela umsebenzi we-DNA gyrase, obangela ukunqotshwa kwekhonkrithi le-bacteria le-DNA futhi okuholela ekufeni kwamagciwane. Umphumela wayo we-bactericidal udlulela kuma-pathogen amaningi angenazimpilo kanye nama-gram-positive, anjengokuthi:

• i-strepto ne-staphylococci;
• amathumbu, i-hemophilic ne-Pseudomonas aeruginosa;
• i-salmonella;
• I-Proteus
• Klebsiella;
• UShigella
• i-citro ne-enterobacteria;
• izivumelwano;
• i-gonococcus;
• i-meningococcus;
• chlamydia
• ama-causative agents we-pseudotuberculosis, induna, inyumoniya, ezinye izifo eziningi zesibhedlela kanye nomphakathi.

Lesi sidakamizwa sithathwa njenge-ejenti enamandla ye-antimicrobial. Isebenza ngokulwa nama-microorganisms amaningi we-pathogenic, aboniswa ukumelana okukhulu kwama-antibacteria kanye nokumelana nesenzo se-sulfonamides, kepha ayisebenzi ekulweni ne-treponema ephaphathekile ne-anaerobes.

Lesi sidakamizwa sithathwa njenge-ejenti enamandla ye-antimicrobial. Isebenza ngokulwa nama-microorganisms amaningi we-pathogenic.

Umphumela we-bactericidal we-Ofloxacin udlulela ku-streptococcal naku-staphylococci.

U-E. coli ubuye azwele ne-Ofloxacin.

I-Ofloxacin iyasebenza ezifweni ezibangelwa yi-salmonella.

I-Pharmacokinetics

Ngemuva kokusebenzisa lesi sidakamizwa okukhulunywa ngaso endaweni yeso, i-ofloxacin ingena ezingxenyeni ezahlukahlukene ze-visual analyzer - i-sclera, cornea kanye ne-iris, i-conjunctiva, umzimba we-ciliary, igumbi elingaphandle lesehlo lamehlo, kanye nemishini yokusebenza kwemisipha. Ukuthola ukugxila okusebenzayo ngokwelashwa ku-vitreous, ukusetshenziswa isikhathi eside kwamafutha kuyadingeka.

Okuqukethwe okuphezulu kwama-antibiotic ku-sclera ne-conjunctiva kutholakala imizuzu emi-5 ngemuva kokuthi umuthi ufinyelele ebusweni beso. Ukungena ngaphakathi kwe-cornea nezendlalelo ezijulile kuthatha ihora elingu-1. Amathishu agcwele kakhulu i-ofloxacin ukwedlula amahlaya amanzi ezinhlamvu zamehlo. Ukugxiliswa okusebenzayo emtholampilo kuyatholakala yize kusetshenziswa umuthi owodwa.

Into esebenzayo empeleni ayingene egazini futhi ayinamphumela ehlelekile.

Yini esiza u-Ofloxacin wamafutha?

Ngenxa yesakhiwo sayo se-bactericidal, into ye -loxacin isetshenziswa kabanzi kwezokwelapha ekwelapheni izifo zezifo zezitho ze-ENT, uhlelo lokuphefumula, kufaka phakathi ukuvuvukala kwamaphaphu, izinso nepheshana lomchamo, ezinye izifo ezithathelwana ngocansi, izilonda zesikhumba, amathambo, i-cartilage nezicubu ezithambile. Ngokuhlanganiswa ne-lidocaine, isetshenziselwa ukulimala kanye nesikhathi se-postoperative.

Ngezifo ezibangelwa amagciwane, amabhali kanye ne-blepharitis, i-oloxacin i-oyili izosizakala.

Ukugcotshwa kwamehlo kwe-Ofloxacin kukhonjelwe i-conjunctivitis, kufaka phakathi amafomu angamahlalakhona.

Izilonda ze-Chlamydia zezitho zombono ziphathwa kusetshenziswa i-ocular oental nge-Ofloxacin.

Izinkomba zokusetshenziswa kwamafutha okugcoba:

1. I-Conjunctivitis, kufaka nezindlela ezingamahlalakhona.
2. Izifo ezibangelwa amagciwane, ibhali, i-blepharitis.
3. I-Blepharoconjunctivitis.
4. I-Keratitis, ulceration of the cornea.
5. I-dacryocystitis, ukuvuvukala kwezihlakala ze-lacrimal.
6. Ukulimala kwezitho zombono nge-chlamydia.
7. Ukutheleleka ngenxa yokulimala kwamehlo noma esikhathini sokusebenza.

Umuthi ungabekwa njengezinyathelo zokuvimbela ukutheleleka nokukhula kokuvuvukala ngemuva kokuhlinzwa amehlo noma ngomonakalo odabukisayo e-orbit.

Contraindication

Lo muthi awusetshenziswanga uma kwenzeka ukungabekezeleli i-ofloxacin noma ezinye izinto ezisizayo, kanye nalapho kukhona ukungahambisani nanoma yikuphi okutholwe ku-quinolone emlandweni. Okunye ukwephulwa:

• ukukhulelwa, noma ngabe kunjani;
• inkathi yokuhlanza;
• iminyaka efinyelela eminyakeni eyi-15;
• i-conjunctivitis engapheli yemvelo engeyona eyegciwane.

Ngaphansi kweminyaka engu-15, kwenqatshelwe ukunquma ukwelashwa nge-Ofloxacin.

Ngesikhathi sokuqunjelwa, ukusetshenziswa kwe-Ofloxacin ku-contraindified.

Kuyenqatshelwa ukusebenzisa lesi sidakamizwa ngesikhathi sokukhulelwa, noma ngabe sinjani.

Ungayifaka kanjani i-Ofloxacin yamafutha?

Umuthi usetshenziswa njengokuyalelwa udokotela ngokuya ngemiyalo etholiwe. Kunconywe kakhulu ukuthi ungazenzisi.

Amafutha kufanele abekwe ngaphansi kwejwabu leso lesehlo elithintekile. Imicu engaba ngu-1 cm isetshenziswa ngqo kwi -hubhu noma ifakwe kuqala emunweni, bese ibekwa kuphela ku-conjunctival sac. Indlela yokuqala iyakhethwa kakhulu, kepha ingadala izinkinga nge-dosing. Kulokhu, kungcono ukubuyela kosizo oluvela eceleni.

Ukuze uzuze ukusatshalaliswa ngisho noma kwesidakamizwa ngemuva kokufaka isicelo, iso kufanele livaleke liguqulwe lisuke ngapha nangapha. Imvamisa enconywayo yokusetshenziswa kwamafutha ayi-2-3 ngosuku. Isikhathi senkambo yokwelashwa akufanele singeqi amasonto ama-2. Ngezilonda ze-chlamydial, i-antibiotic iphathwa izikhathi ezi-5 ngosuku.

Ngaphezu kwamafutha, amaconsi wamehlo nge -loloacacin asetshenziswa kumkhuba we-ophthalmic. Ukusetshenziswa okufanayo kwalezi zinhlobo zama-dosage kuvunyelwe, inqobo nje uma ukugcotshwa kwamafutha kuzosetshenziswa ekugcineni. Ngokusetshenziswa okuvela kokunye kokulungiselela kwamehlo, umuthi okukhulunywa ngawo ubekwa phansi ngaphambi kwemizuzu engu-5 emva kwawo.

Ngoshukela

Ku-diabetes, ingozi yokuphendula okubi iyanda. Ngakho-ke, lesi sidakamizwa kufanele sisetshenziswe ngokuqapha, sazise udokotela oholayo ngalo lonke ushintsho olungathandeki.

Ezinye iziguli zikhononda ngobuhlungu besisu.

Ku-diabetes, ingozi yokuphendula okubi iyanda.

Ukwanda kwezithombe kungenye yemiphumela emibi yesidakamizwa.

Amafutha kufanele abekwe ngaphansi kwejwabu leso lesehlo elithintekile.

Ngaphezu kwamafutha, amaconsi wamehlo nge -loloacacin asetshenziswa kumkhuba we-ophthalmic.

Imiphumela emibi yamafutha e-Ofloxacin

Lo muthi kwesinye isikhathi ubangela ukusabela kwendawo endaweni yokusebenza. Babonakala ngesimo sokubomvu kwamehlo, i-lacrimation kanye nokomisa ngaphandle kwe-mucous surface, ukulunywa, ukuvutha, ukukhuphuka kwe-photosensitivity, isiyezi. Ezimweni eziningi, lezi zimpawu zimnene, zesikhashana, futhi azidingi ukwelashwa.

Kepha eminye imiphumela emibi evela ezinhlotsheni ezahlukahlukene zomzimba iyenzeka, yize inesimo sezidakamizwa ezifanayo ze-systemic.

Amapheshana wesisu

Ezinye iziguli zikhononda nge-nausea, ukubukeka kokuhlanza, ukulahlekelwa yinhliziyo, umlomo owomile, nobuhlungu besisu.

Izitho zeHematopoietic

Izinguquko ezinqala ekwakhiweni kwegazi zingabonakala.

Isistimu yezinzwa ephakathi

Isiyezi, i-migraines, ubuthakathaka, ukukhuphuka kwengcindezi ye-endocranial, ukungaxineki okuphezulu, ukuqwasha, ukucwilisa ukunyakaza, ukucwaswa, ukuhlukunyezwa kwezitho zangasese.

Kusuka ohlelweni lomchamo

Ngezinye izikhathi kuvela izilonda ze-nephrotic, i-vaginitis iba.

Njengomphumela omubi, i-bronchospasm ingahle ikhule.

Kwezinye izimo, iziguli zine-myalgia.

Isiyezi kungenzeka ngenxa yokusebenzisa umuthi.

Izinguquko ezinqala ekwakhiweni kwegazi zingabonakala.

Kwezinye izikhathi i-vaginitis iba.

Kusuka ohlelweni lokuphefumula

Kungenzeka i-bronchospasm.

Kusuka ohlelweni lwezinhliziyo

Ukuwohloka kwemithambo kuye kwabikwa.

Kusuka ohlelweni lwe-musculoskeletal

Kwezinye izimo, i-myalgia, i-arthralgia, kanye nomonakalo we-tendon kuyaphawulwa.

Allergies

I-erythema engaba khona, i-urticaria, ukulunywa, ukudumba, kufaka phakathi i-pharyngeal, anaphylaxis.

Umthelela ekhonweni lokulawula izindlela

Ngenxa yokusebenzisa amafutha, i-lacrimation, umbono ophindwe kabili, isiyezi kungenzeka, ngakho-ke kungakuhle ukwenqabe ukushayela nezinqubo eziyinkimbinkimbi.

Imiyalo ekhethekile

Umuthi usetshenziswa ngokuqapha lapho kukhona izingozi ze-cerebrovascular kanye nezilonda ze-organic zohlelo lwangaphakathi lwezinzwa.

Izibuko zinconyelwa ukunciphisa ukuzwela okukhanyayo.

Ngesikhathi sokulashwa nge-Ofloxacin, umuntu kufanele ayeke ukusebenzisa ama-lens athintana nawo.

Ngemuva kokufaka amafutha, kuhlonishwa okwesikhashana ekuboneni okubonakalayo, okuvame ukudlula emizuzwini eyi-15.

Ngesikhathi sokulashwa nge-Ofloxacin, umuntu kufanele ayeke ukusebenzisa ama-lens athintana nawo.

Amafutha akufanele abekwe kwi-sac ephezulu kakhulu ye-conjunctival. Ngemuva kokusetshenziswa kwayo, ukuwohloka kwesikhashana ekuboneni okubonakalayo kuyabonakala, okuvame ukudlula emizuzwini eyi-15.

Izibuko zinconyelwa ukunciphisa ukuzwela okukhanyayo.

Ngesikhathi sokwelashwa, ukunakekelwa kwamehlo okuhlanzekile kuyadingeka.

Sebenzisa ebudaleni

Ukuhlanganiswa kwamafutha ngama-ejenti ama-hormone kufanele kugwenywe.

Isabelo sezingane

Ebuntwaneni, umuthi awusetshenziswa. Umkhawulo weminyaka ungafika eminyakeni eyi-15.

Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba

Abesifazane ababekelwe umuthi esiteji sokukhulelwa. Omama abangabahlengikazi kufanele bayeke ukondla ngokwemvelo isikhathi sokwelashwa futhi babuyele kukho kungakadluli usuku olulodwa ngemuva kokuphela kwenkambo yokwelashwa.

Ukweqisa

Amacala okweqisa kwamafutha awazange abhalwe.

Amacala okweqisa kwamafutha awazange abhalwe.

Ukuxhumana nezinye izidakamizwa

Uma kusetshenziswa ezinye izidakamizwa ekwelapheni izitho zombono, i-Ofloxacin isetshenziswa okokugcina, sesilinde imizuzu eyi-15 ukuya kwengama-20 emva kwenqubo eyedlule. Ngokusetshenziswa okufanayo kwalokhu kugcotshwa nama-NSAIDs, amathuba okuphendula kwe-neurotoxic ayanda. Ukulawulwa okukhethekile kuyadingeka lapho kusetshenziswa kanye nama-anticoagulants, insulin, cyclosporine.

Ukuhambisana notshwala

Ngomuthi olwa namagciwane, ukusetshenziswa kwemikhiqizo equkethe utshwala kuyenqatshelwe. Ukwehluleka ukwenza njalo kungahle kuholele ekuphenduleni okunjenge-disulfiram.

Ama-Analog

I-Ofloxacin isetshenziswa ezibhebheni noma njengomjovo ukunikeza umphumela we-systemic. Amaconsi wamehlo nezindlebe ayatholakala. Ngokwesivumelwano nodokotela, zingathathelwa indawo yilokhu okulandelayo:

• I-Phloxal;
• Azitsin;
• I-Oflomelide;
• I-Vero-Ofloxacin;
• Oflobak;
• U-Ofloxin nabanye

I-Phloxal yeso yamafutha iqukethe i-Ofloxacin antibiotic.

I-Oflomelide ngenye i-analogue yesidakamizwa.

I-Ofloxacin esezibhebheni isetshenziselwa ukunikeza imiphumela ehlelekile.

Imibandela yekhefu lekhemisi

Umuthi okukhulunywa ngawo umuthi.

Intengo

Izindleko zamafutha zivela kuma-ruble angama-48. nge-5 g.

Izimo zokugcina zomuthi

Umuthi kufanele ugcinwe kude nezingane, uvikeleke elangeni eliqondile. Ukushisa kwesitoreji akufanele kudlule + 25 ° С.

Isikhathi sokuphelelwa yisikhathi

Ngefomu evaliwe, umuthi ugcina izindawo zawo zokuphulukisa iminyaka engu-5 kusukela ngosuku lokukhishwa. Ngemuva kokuvula i-tube, i-ointment kufanele isetshenziswe kungakapheli amasonto ayi-6. Ukusetshenziswa kwemikhiqizo ephelelwe isikhathi kuvinjelwe.

Umkhiqizi

E-Russia, ukukhiqizwa kwamafutha kwenziwa nge-Synthesis OJSC.

Ukubuyekezwa

UGeorge, oneminyaka engama-46, e-Ekaterinburg.

Umuthi awubizi futhi uyasebenza. Welashwa yi-conjunctivitis enzima ngezinsuku ezi-5. Akubanga namiphumela emibi, kepha bekucasula kakhulu ukuthi ngemuva kokufiphaza amehlo konke kufiphale. Kwakufanele ngilinde isikhathi eside kuze kugcotshwe uwoyela, futhi umbono uzobuyela kokujwayelekile.

U-Angela, oneminyaka engama-24, Kazan.

Ngemuva kohambo oluya olwandle, amehlo akhe aphenduka abomvu. Udokotela uthe kwakuwukutheleleka futhi wanquma i-Ofloxacin njengezithambiso. Kwangiphatha kabi kabi lapho ngithola ukuthi amalensi okuxhumana kufanele abekwe eceleni futhi agqoke izibuko ngize ngilashwe. Kepha umuthi ubhekane nalesi sifo ngokushesha ngokwanele. Kungemva kokufaka isicelo kuphela lapho kwashisa kancane.

U-Anna, oneminyaka engama-36, uNizhny Novgorod.

Bengicabanga ukuthi ukugcotshwa kwamafutha e-Ofloxacin kwakudingeka ekwelapheni amanxeba futhi ngamangala lapho umama wami eyinikeza i-blepharitis. Kokubili ukubomvu nokuvuvukala kudlule ngokushesha, kepha ukwelapha amehlo ngamaconsi kulula kakhulu.