IBenfolipen iyinkimbinkimbi ehlangene yamavithamini ekwelashweni kwezifo zemizwa. Umuthi lo uthuthukisa ukwakheka kwama-metabolism kumaseli nezicubu, kusiza ukudambisa izinhlungu. Akubangeli ubuthi kanye nezinguquko ezingafuneki emzimbeni, noma kusetshenziswa isikhathi eside.
Igama Lezwe elingafanele
INN - Multivitamine.
I-ATX
Ukubhalwa kwe-ATX - A11BA. Kungokwama-multivitamini.
Khipha amafomu nokwakheka
Ikhiqizwa ngendlela yamathebulethi. Ithebhulethi ngayinye iqukethe uhlobo oluyinhlanganisela yamavithamini B1 (100 mg), cyanocobalamin (0.002 mg), pyridoxine hydrochloride (100 mg). Ngokwengeziwe, ukwakheka kuqukethe i-carmellose noma i-carboxymethyl cellulose, hydroxypropyl cellulose, hyprolose, collidone, talc, calcium usaric usawoti, phakathi kuka-80, ushukela.
IBenfolipen iyinkimbinkimbi ehlangene yamavithamini ekwelashweni kwezifo zemizwa.
Izibhebhe zihlanganiswe nefilimu kusuka ku-macrogol, polyethylene oxide, isisindo esincane se-polyvinylpyrrolidone yezokwelapha, i-titanium dioxide, i-talc.
Wonke amaphilisi asephaketheni elingemidwebo yeseli lezingcezu eziyi-15.
Isenzo se-Pharmacological
Umphumela emzimbeni ubangelwa ukuba khona kwamavithamini eqembu B. Izinhlobo ze-thiamine ze-soluble thiamine, i-benfotiamine, zibamba iqhaza elibonakalayo ezinqubweni ze-conduction of nerve impulses. I-Pyridoxine hydrochloride noma i-Vitamin B6 ilawula ukuqina kwamaprotheni, amafutha nama-carbohydrate. Ngaphandle kwawo, ukwakheka kwegazi okujwayelekile kanye nokusebenza kohlelo lwezinzwa akunakwenzeka. Ihlanganyela ekwakhiweni kwama-nucleotides.
IVitamin B6 inikezela ngokudluliselwa okusebenzayo kokufakwa kwezinzwa ngama-synapses, kusebenze ukwakheka kwama-catecholamines.
ICyanocobalamin, noma uvithamini B12, ubandakanyeka ekwakhekeni nasekukhuleni kwamaseli e-epithelial, kanye nasendleleni ye-myelin ne-folic acid. Ngokuntuleka kwayo, ukwakheka kwamangqamuzana egazi abomvu akunakwenzeka.
I-Pharmacokinetics
Ngemuva kokuphathwa ngomlomo, ifomu le-thiamine elinganyibilikisi lithakwa ngokushesha emgudwini wokugaya ukudla. Ngaphambi kwalokhu, kukhishwa kusetshenziswa ama-enzymes wokugaya ukudla. Ngemuva kwekota yehora, kuvela egazini, futhi emva kwengxenye yehora - kwezicubu namaseli. I-thiamine yamahhala itholakala ku-plasma, futhi amakhompiyutha ayo ahlanganisana namaseli egazi.
Ngemuva kokuphathwa ngomlomo, ifomu le-thiamine elinganyibilikisi lithakwa ngokushesha emgudwini wokugaya ukudla.
Inani eliphambili laleli khompiyutha lisemithanjeni wenhliziyo nemithambo, izicubu zezinzwa, kanye nesibindi. Ngaphansi kwengxenye yento ihlanganiswe kwezinye izitho nezicubu. Kukhishwa emzimbeni kusuka ezinsweni nasemathunjini, ngomunyu.
I-Pyridoxine idonswa ngokushesha ukuphathwa komlomo. Izibopho kumaprotheni e-plasma. Inqubo yokucutshungulwa kwezicubu zesibindi iyaqhubeka. Ibekwe emsipha wamathambo. I-Excretion yenziwa ngomchamo ngesimo se-metabolite engasebenzi.
ICyanocobalamin iguqulwa ibe yi-coenzyme metabolite kwezicubu. Kukhishwa emzimbeni nge-bile nomchamo.
Izinkomba zokusetshenziswa
Umuthi usetshenziselwa ukwelashwa okuyinkimbinkimbi kwama-pathologies:
- ukuvuvukala kwe-neuralgic yezinzwa ye-trigeminal nerve;
- i-neuritis
- ubuhlungu bamazinga ahlukahlukene abangelwa izifo zomgogodla (i-neostgial neuralgia, i-lumbar ischialgia, i-radicular syndrome, isibeletho, i-cervicobrachial, i-lumbar syndromes);
- izinguquko eziwohlokayo emgogodleni;
- isifo sikashukela se-polyneuropathy;
- ukulimala kotshwala ohlelweni lwezinzwa;
- i-plexitis (ebekiwe njengengxenye yokwelashwa okuyinkimbinkimbi nezidakamizwa ezingenayo ukuxhumana kwezidakamizwa);
- i-paresis yezinzwa (ikakhulukazi ubuso).
Umuthi uBenfolipen usetshenziselwa ukwelashwa okuyinkimbinkimbi kwama-pathologies, ngokwesibonelo, ngezinga elihlukile lobuhlungu bezinhlungu obubangelwa izifo zomgogodla.
Contraindication
Umuthi uphuliwe:
- ukuzwela okuphezulu kwamavithamini enza umkhiqizo;
- izigaba ezibunjiwe zokuhluleka kwenhliziyo;
- ukukhulelwa
- iminyaka (kuze kube yiminyaka eyi-14).
Ungayithatha kanjani iBenfolipen
Imiyalo esetshenzisiwe ikhombisa ukuthi umuthi uthathwa ngemuva kokudla. Amathebulethi akufanele ahlafunwe, aqhekeke noma aqhekeke. Udinga ukubaphuza ngenani elincane loketshezi. Umthamo ojwayelekile yithebhulethi 1 kuya kwabathathu ngosuku.
Isikhathi sesifundo sisetwa ngudokotela oholayo. Ungawusebenzisi umuthi isikhathi esingaphezu kwezinsuku ezingama-28.
Imithamo yemithamo nemithamo ingahluka kuye ngecala ngalinye. Imiyalo kadokotela iqinisekisa ukuqokwa ngqo kweBenfolipen futhi ithola umphumela odingekayo wokwelapha.
Ngoshukela
Amathebulethi aqukethe i-sucrose. Esikhathini sikashukela, ukunakekelwa kufanele kuthathwe lapho kuthatha, ngoba kungasiza ukukhulisa i-glycemia. Ukulungiswa komthamo weBenfolipen noma i-insulin kuyadingeka uma isiguli sinendlela ebolile yesifo sikashukela.
Uma ushukela wesiguli unxephezelwe, khona-ke amaphilisi anjalo angaphuzwa ngaphandle kwemikhawulo. Odokotela batusa ukusebenzisa lesi sidakamizwa ezimweni zokuphazamiseka kwe-nerve conduction ku-neuropathies yesifo sikashukela kanye nezinye izifo zesistimu yezinzwa.
Esikhathini sikashukela, kubalulekile ukuvimbela ukuzelapha, ukwanda okungagunyaziwe noma ukwehla komthamo wokwelapha weBenfolipen. Konke lokhu kungathinta kabi inkambo yesifo sikashukela.
IBenfolipen ingadala ukujuluka okuthe xaxa, i-tachycardia, kanye nenausea.
Imiphumela emibi Benfolipena
Umuthi ungadala ukukhuphuka kokujuluka, i-tachycardia kanye nenausea. Imvamisa ukuthuthukiswa kokungezwani komzimba ngendlela yokubukeka kwesikhumba nokubukeka kokuqhuma kukho. Izimo ezinjalo zidlula ngokushesha futhi azidingi ukuphathwa okwengeziwe kwezidakamizwa.
Amaqembu alandelayo emiphumela emibi angavela kumuntu:
- Ukuphazamiseka ekusebenzeni okujwayelekile kwesisu namathumbu. Isicanucanu, ukuhlanza, nobuhlungu esiswini kuyakhula. Ebantwini, inani le-hydrochloric acid esejameni lesisu linganda. Imvamisa, isifo sohudo sijoyina lezi zimpawu.
- Ukungasebenzi kwenhliziyo - ukuqina kokuqina okukhulu, ukubukeka kobuhlungu obukhulu enhliziyweni. Ezimweni ezimbi kakhulu, isimo se-collaptoid senzeka ngenxa yokwehla okukhulu futhi kungazelelwe komfutho wegazi. Kuyaqabukela, kuvimbele inhliziyo, kuvimbele uhlelo lwe-conduction.
- Ukuphazamiseka kusuka esikhunjeni - ukulunywa kanzima futhi okunzima, ukuvuvukala, i-urticaria. Ezimweni ezingavamile, ukuthuthukiswa kwesikhumba kanye ne-angioedema kungenzeka.
- Izinguquko emasosheni omzimba - I-edema kaQuincke, ukujuluka okuqinile. Ezimweni ezingavamile, ngokuzwela okwengeziwe, isiguli singaba ne-anaphylactic shock.
- Kukhona ukuphazamiseka komsebenzi ohlanganisiwe wesistimu yezinzwa. Ukukhathazeka okuveziwe, ubuhlungu endaweni yekhanda kungavela. Imvamisa ngokuphazamiseka okukhulu ohlelweni lwezinzwa, ukulahleka kwesikhashana, ukwazi ukozela okukhulu ngesikhathi sasemini, nezinkinga zokulala ebusuku kungenzeka. Imithamo ephezulu yemithi idala ukuqina, umsebenzi owandayo. Ezimweni ezingavamile, ukuboshwa kwenhliziyo kungazelelwe kwenzeka.
Eminye imiphumela emibi evela ekusetshenzisweni kweBenfolipen ingavela:
- umuzwa we-tinnitus okhonjiwe;
- ukudangala kwenqubo yokuphefumula, kwesinye isikhathi umuzwa wokuntuleka komoya;
- ubukhulu bezingalo nemilenze;
- iminyakazo
- umkhuhlane ohambisana nomuzwa wokushisa;
- ubuthakathaka obukhulu;
- izimpukane ezifiphayo namachashazi amnyama emehlweni;
- ukuvuvukala kwe-conjunctival;
- kuzwakalise ukuzwela kwamehlo kukhanye ukukhanya kwelanga.
Zonke lezi zinto zingenzeka kuphela ngokuzwela okuphezulu ezingxenyeni zomuthi futhi zidlule ngokushesha. Ezimweni ezihlukile, kukhombisa ukwelashwa okubonakalayo.
Umthelela ekhonweni lokulawula izindlela
Akukho datha ngomphumela womkhiqizo ekhonweni lokulawula izindlela eziyinkimbinkimbi nokushayela imoto. Uma umuntu ethambekele ekubeni nesiyezi, ingcindezi iyehla, kubalulekile ukushiya okwesikhashana imisebenzi edinga ukunakwa okwengeziwe nokusabela okusheshayo.
Uma umuntu ethambekele ekubeni nesiyezi, ingcindezi iyehla, kubalulekile ukushiya okwesikhashana imisebenzi edinga ukunakwa okwengeziwe nokusabela okusheshayo.
Imiyalo ekhethekile
Ngesikhathi sokwelashwa, akunconywa ukusebenzisa izakhiwo ze-multivitamin eziqukethe amavithamini B. Ukwehluleka ukugcina lo mthetho kuholela ku-hypervitaminosis B. Izimpawu ze-hypervitaminosis:
- i-arousal - inkulumo kanye ne-motor;
- ukuqwasha
- ukuzwela okwengeziwe kwesikhumba kokukhuthazeka kwangaphandle;
- ikhanda elichithekile;
- isiyezi esinzima;
- iminyakazo
- ukwanda nokwanda kwesilinganiso senhliziyo.
I-overdose ye-Vitamin B1 ibonakala ngokuvela kokuqhuma engxenyeni, entanyeni, esifubeni kanye nasekunyukeni kokushisa komzimba. Ukubonakaliswa okungenzeka kokungasebenzi kwezinso kuze kube sekupheleni ngokuphelele kwenqubo yokukhiqiza umchamo. Ukuhlukumezeka kwemithamo ephezulu ye-vithamini B1 kuholela ekwandeni kokuzwela kwesikhumba emisebeni ye-ultraviolet.
Ngokwanda kokuqukethwe kwe-pyridoxine, ukubanjwa ngamandla, ukufikelwa yimizwa, kanye nokwanda kwe-acidity yejusi esiswini kungenzeka. Kulokhu, kufanele kuqashelwe nemithamo yomuthi kubantu abanesifo se-gastritis esingelapheki.
Ukufakwa kwenani elikhulu le-vithamini B12 kungavusa ukungezwani komzimba kuze kufike ekuqhekekeni kwe-anaphylactic.
Sebenzisa ebudaleni
Akukho datha ezinhlelweni zokusebenzisa umkhiqizo esikhathini esidala. Endabeni yezifo zesibindi, izinso, ukwehluleka kwenhliziyo, kuyinto efiselekayo ukwehlisa umthamo ube osezingeni eliphansi.
Ngempilo enhle, asikho isidingo sokushintsha umthamo obekiwe ngaphambili weBenfolipen. Abantu abanjalo bakubekezelela kahle ukuphathwa, ukulungiswa okwengeziwe akudingekile.
Isabelo sezingane
Kunqatshelwe ngokuphelele ukunikeza izingane. Akunasipiliyoni ngokusetshenziswa kwalesi sidakamizwa ekuziphatheni kwezingane. Uma izingane zinezimpawu noma izifo, khona-ke zinqunyelwa eminye imithi enomphumela ofanayo, kepha ingenawo amavithamini amaningi we-B.
Imithamo ephezulu yamavithamini B1 no-B6 ingaba yingozi ezinganeni.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Ngesikhathi sokukhulelwa, kwenqatshelwe ukuthatha umuthi. Imithamo emikhulu ye-pyridoxine ingaba nomphumela onobuthi ku-fetus. Ukuqokwa lapho ibele alivunyelwe. Amavithamini ayakwazi ukungena ubisi lwebele futhi alimaze kabi impilo yengane.
Isicelo sokusebenza kokulimala kwezinso
Ukuqapha kufanele kusetshenziswe lapho kusetshenziswa iziguli ezingasebenzi kahle izinso. Umthamo okhethwe ngokungalungile unikela ekungasebenzi kahle kwezinso, ukuncipha kwenani lomchamo okhiqizwayo.
Sebenzisa umsebenzi wesibindi okhubazekile
Ngezifo zesibindi esigabeni esibulalayo, ukusetshenziswa kwamavithamini we-B kukhonjiswa kuphela ngemuva kokuhlolwa okuningiliziwe kwezokwelapha kanye nedosi elisebenza ngokulingene. Kunobungozi obukhulu bokweqisa kwezifo zesibindi.
I-Benfolipen I-overdose
Uma kwenzeka kweqa ngokweqile, izimpawu zemiphumela emibi yeBenfolipen ziyandiswa. Uma isiguli siphuza imali enkulu, kudingeka siphuze amaphilisi ekhabhoni. Ukwelashwa okubonakalayo kukhonjiswa ngokuya ngokuthi yiziphi izimpawu ezinobuthi ezikhona.
Ukuxhumana nezinye izidakamizwa
Umuthi uguqula umsebenzi we-pharmacological wezidakamizwa ezithile:
- Yehlisa umsebenzi weLevodopa.
- Ukusetshenziswa kwe-biguanides ne-colchicine kunciphisa umsebenzi we-vitamin B12.
- Ngokusetshenziswa isikhathi eside kwePhenobarbital, Phenytoin, Carbamazepine, ukuntuleka kwe-thiamine kwenzeka.
- Ukusetshenziswa kwe-Isoniazid noma iPenicillin kunciphisa umsebenzi we-Vitamin B6.
Ukuhambisana notshwala
Ukuphuza utshwala kunciphisa kakhulu ukumuncwa kwe-thiamine namanye amavithamini e-B.
Ama-Analog
Imithi enendlela efanayo yokusebenza emzimbeni:
- I-Neuromultivitis;
- Kombilipen;
- I-Angiitis;
- Undevit;
- Vetoron;
- I-Unigamm
- Neurobion;
- Neurolek;
- I-Neuromax;
- Neurorubin;
- Milgma.
Imibandela yekhefu lekhemisi
Ithuluzi lingathengwa ngemuva kokwethula umuthi ekhemisi.
Ngingakwazi ukuthenga ngaphandle kadokotela
Kwamanye amakhambi, kungenzeka ukuthenga iBenfolipen ngaphandle kokwethula incwadi kadokotela. Isiguli esithenga umuthi kanye ne-analogues yaso sisengozini enkulu ngenxa yengozi yokuthola umkhiqizo osezingeni eliphansi noma ongekhohlisayo noma ukubonakala kwemiphumela engalindeleki emzimbeni.
Intengo yeBenfolipen
Izindleko zokufaka umuthi ezibhebheni ezingama-60 zivela kuma-ruble ayi-150.
Izimo zokugcina zomuthi
Umuthi kufanele ugcinwe ebumnyameni, upholile futhi uvikeleke ezinganeni. Izinga lokushisa kufanele libe lokushisa lasekamelweni. Kuvunyelwe ukuthola umuthi esiqandisini.
Isikhathi sokuphelelwa yisikhathi
Umuthi ungadliwa kungakapheli iminyaka emi-2 kusukela ngosuku lokukhiqizwa. Ngemuva kwalesi sikhathi, ukuphuza amaphilisi anjalo akuvunyelwe ngokuphelele, ngoba ngokuhamba kwesikhathi, umphumela wamavithamini uyashintsha.
Umkhiqizi
Umuthi lo ukhiqizwa enkampanini i-Pharmstandard-UfaVITA e-Ufa.
Ukubuyekezwa kweBenfolipin
U-Irina, oneminyaka engama-58, eMoscow: "Nginesifo sokuqubuka komgogodla esingapheli, esihambisana nobuhlungu obukhulu. Ngingene kaningi emabhulokini, kodwa ngiyazi ukuthi ziyingozi empilweni futhi azilethi ukukhululeka. Udokotela ungeluleke ukuthi ngiphuze amaphilisi eBenfolipen ukuze ngikwazi ukubuyisa izicubu zomzimba ezivamile. Ezinsukwini ezimbalwa kusukela kuqale ukwelashwa izinhlungu zaphela, isimo sasesingcono.
UPolina, oneminyaka engama-45, eSt.Ngaphezu kwalokho, i-novocaine blockade ihlala isikhathi esincane. Ngokweseluleko udokotela, waqala ukuphuza umuthi 1 ithebhulethi 3 ngosuku. Ezinsukwini ezimbalwa, ukuqina kobuhlungu eceleni kwezinzwa kunciphile, bese kuthi ukwanda kwesifo kudlule. Ngemuva kwenkambo yokwelashwa ngizwa kahle. "
USergey, oneminyaka engama-47, uPetrozavodsk: "Waphuza umuthi wezifo zomgogodla. Wezwa izinhlungu ezinzima nokuqina kokunyakaza kunoma yiluphi ushintsho lwesimo sezulu. Ukwenza ngcono isimo sakhe, udokotela watusa ukuthatha lo muthi amasonto ama-3, amaphilisi ama-3 ngosuku. Amavithamini asiza ngokushesha. Manje akukho okungajabulisi umuzwa emgogodleni, ngikwazi ukuhamba ngokujwayelekile. Akunamiphumela emibi eye yabonwa ngesikhathi sokwelashwa. "
