Umuthi i-Lomflox usetshenziselwa ukwelapha ama-pathologies athathelanayo wemvelaphi ehlukahlukene. Ifomethi yokukhishwa elula nentengo ephansi ikwenze kwathandwa emakethe yemithi.
Igama Lezwe elingafanele
I-Lomefloxacin (Lomefloxacin).
I-ATX
J01MA07.
Umuthi i-Lomflox usetshenziselwa ukwelapha ama-pathologies athathelanayo wemvelaphi ehlukahlukene.
Khipha amafomu nokwakheka
Umuthi uyenziwa ngefomethi yethebhulethi. Izibhebhe zigcwele amapuleti ama-5 noma ama-4 ama-pcs. Ebhokisini eli-1 lekhadibhodi 5, 4 noma 1 blister kanye nemiyalo yokusebenzisa.
Isakhi esisebenzayo yi-lomefloxacin (400 mg kwithebhulethi ngayinye). Izingxenye ezisizayo:
- i-talcum powder ehlungiwe;
- polyvinylpyrrolidone;
- i-lactose;
- i-sodium lauryl sulfate;
- i-crospovidone;
- i-magnesium stearate;
- i-sodium starch glycolate;
- silica colloidal.
Umuthi uyenziwa ngefomethi yethebhulethi.
Igobolondo yethebhulethi liqukethe i-titanium dioxide, isopropanol, hydroxypropyl methylcellulose ne-methylene chloride.
Isenzo se-Pharmacological
I-Lomefloxacin iyinto eyenziwe ngokwenziwe ngemithi yokubulala amagciwane ngomsebenzi owenziwe ngokuthiwa yi-bactericidal. Umuthi ungowesigaba se-fluoroquinolones.
Umgomo wesenzo se-pharmacotherapeutic wezidakamizwa uchazwa ngekhono laso lokucindezela imisebenzi ye-bacterial gyrase ye-bacteria. Umuthi uyasebenza ngokulwa namagciwane anjengalawa:
- igciwane le-aerobic le-gram-negative ne-gram-positive aerobic bacteria: iMoaxella catarrhalis, Serratia marcescens, Proteus stuartii, Staphylococcus epermidis, Staphylococcus aureus nabanye;
- i-mycobacteria ye-tuberculous, chlamydia, i-enterococcus, inombolo yezinhlobo eziningi ze-ureaplasma ne-mycoplasma.
Umphumela wokwelapha umuthi uyancipha endaweni ene-acid. Lapho usebenzisa umuthi, ukumelana nemiphumela yako kukhula kancane kakhulu.
I-Pharmacokinetics
Lapho esegunjini lokugaya ukudla, umuthi uqala ukudonswa ngokushesha.
I-Cmax ibonwa ngemuva kwemizuzu engama-90-120. Into ebopha amaprotheni e-plasma ngamaphesenti ayi-10. Ingeniswa ngokushesha kuma-biofluid nezicubu zomzimba.
Lapho esegunjini lokugaya ukudla, umuthi uqala ukudonswa ngokushesha.
Ukuphila kwengxenye kuthatha amahora ayisikhombisa kuya kwayi-9. Cishe i-70-80% ye-MS ikhishwa umchamo emahoreni angama-24.
Izinkomba zokusetshenziswa
Umuthi wenzelwe ekwelapheni ama-pathologies okuvuvukala / wokutheleleka acasulwa ngamagciwane ahlukahlukene:
- ukutheleleka kwamathambo kanye nokuhlangana (kufaka phakathi i-osteomyelitis engapheli);
- ukutheleleka kwezicubu ezithambile nesikhumba (kufaka phakathi i-sinusitis);
- ukutheleleka okwenziwe endaweni ohlelweni lwezitho zofuzo;
- ukuxutshwa, i-gonococcal, izilonda ezithathelanayo ze-chlamydial;
- abezindaba ze-otitis (abaphakathi);
- isifo sofuba samaphaphu.
Ngaphezu kwalokho, umuthi usetshenziselwa ukuvikela ukwenzeka kwezifo ngesikhathi sokuhlinzwa kwe-transurethral.
Contraindication
- iminyaka engaphansi kweminyaka eyi-15;
- ukucaphuka
- hypersensitivity kuma-quinolones.
Ngokunakekela
Umuthi olwa namagciwane ubekelwe ngokucophelela izimo zesifo sokuwa, isifo sokuqina kwamathambo nezinye izifo ezihambisana nokuthathwa.
Ungayithatha kanjani iLomflox
I-MS isetshenziswa ngomlomo futhi ihlanzwa ngamanzi. Ukudla akuphuli isenzo sawo.
Umthamo ophakathi ngosuku ama-milligram angama-400 ngosuku. Ezigulini ezinezinkinga zezinso, i-400 mg yomuthi inqunyelwa ngosuku lokuqala, kanye nama-200 mg (isigamu sethebhulethi) ngosuku ngezinsuku ezilandelayo.
Isikhathi sokwelashwa kuya ngezinkomba:
- ifomu elibanzi le-chlamydia: amaviki ama-2;
- izifo ezithinta umchamo: kusuka ezinsukwini ezintathu kuya kwezingu-14;
- ukutheleleka kwesikhumba: kusuka kumaviki awu-1.5 kuya kwayi-2;
- isigaba sokwanda kwe-bronchitis: kusuka kumaviki awu-1 kuye kwayi-1.5;
- isifo sofuba: Amaviki ama-4 (kuhlangene ne-ethambutol, isoniside neparisinamide).
Ukuze uvimbele ukutheleleka kwezinqubo zokuzala kanye nokuchama ngemuva kokuhlinzwa kwe-transurethral kanye ne-prostopia biopsy, kunconyelwa ukuphuza ithebhulethi eyi-1 amahora ambalwa ngaphambi kokuhlolwa noma ukuhlinzwa.
Ukuthatha umuthi wesifo sikashukela
Abantu baleli qembu kufanele bathathe amazinga kashukela lapho bethatha izidakamizwa. Imithamo ikhethwe udokotela ngamunye.
I-MS isetshenziswa ngomlomo futhi ihlanzwa ngamanzi.
Imiphumela emibi yeLomfox
Amapheshana wesisu
- Ubuhlungu nokuvuvukala kwe-mucosa yomlomo;
- izihlakala;
- isicanucanu
- kuqhuma esiswini.
Izitho zeHematopoietic
- i-thrombocytopenia elinganiselayo;
- i-hemolytic hlobo anemia.
Isistimu yezinzwa ephakathi
- i-ataraxia;
- ukuphazamiseka kwengqondo;
- ukuthuthumela nokugungqa;
- ikhanda
- ukuqwasha
- ukwesaba ukukhanya;
- isibonakaliso se-diploptic;
- ushintsho lokunambitha;
- ukuphazamiseka komoya okucindezelayo;
- imibono.
Kusuka ohlelweni lomchamo
- indlela yangaphakathi ye-jade;
- ukukhuphula ukwehluleka kwezinso;
- i-polyuria;
- ukopha kwe-urethral;
- ukugcinwa komchamo.
Kusuka ohlelweni lokuphefumula
- ukuvuvukala komgogodla kanye / noma amaphaphu.
Engxenyeni yesikhumba
- i-photosensitivity;
- I-Stevens-Johnson syndrome;
- dermatitis (exfoliative);
- imibala.
Kusuka ohlelweni lwezinhliziyo
- ukucindezelwa kwemisipha yenhliziyo;
- i-vasculitis.
Allergies
- i-angioedema;
- i-allergic rhinitis;
- ukuluma nokuvuvukala.
Umthelela ekhonweni lokulawula izindlela
Umuthi kwesinye isikhathi ubangela isiyezi nokulimazeka ukungasebenzi, ngakho-ke ngesikhathi sokwelashwa kufanele unqabe ukuphatha imishini eyinkimbinkimbi nokwenza umsebenzi odinga ukuphendula nokunakwa okusheshayo.
Imiyalo ekhethekile
Ngesikhathi sokusetshenziswa kwamathebhulethi, kungakuhle ukuthi uvikele ukuvezwa isikhathi eside elangeni elivulekile. Ubungozi bokubonakaliswa kwe-photochemical ngaphansi kwethonya lokukhanya kwelanga bungancishiswa kakhulu uma uphuza umuthi njalo kusihlwa.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Imiyalo yezidakamizwa iyakwenqabela ukusetshenziswa kwabesifazane abakhulelwe / abancelayo izisu.
Imiyalo yezidakamizwa iyakwenqabela ukusetshenziswa kwabesifazane abakhulelwe.
Ukunquma uLomflox ezinganeni
Isithasiselo ekwelashweni sinqabela ukusetshenziswa kwayo yiziguli ezineminyaka engafiki kwengu-15.
Sebenzisa ebudaleni
Ukukhetha okukhethekile komthamo akudingeki.
Isicelo sokusebenza kokulimala kwezinso
Umthamo unqunywa ngokuya ngezinkomba zomtholampilo.
Sebenzisa umsebenzi wesibindi okhubazekile
Ukulungiswa kwedosi akudingekile lapho kungekho msebenzi we-renal ophazamisekile.
Ukulungiswa kwedosi akudingekile lapho kungekho msebenzi we-renal ophazamisekile.
I-Overdose yeLomfox
Ekuhlolweni kwelabhoratri, azange kube namacala okuvela okuphikisayo okuphikisayo ngenxa yokweqisa ngokweqile.
Ukuxhumana nezinye izidakamizwa
Kwenqatshelwe ukuhlanganisa umuthi ne-rifampicin.
Amavithamini, ama-antacid kanye nama-antibacterial agents, aqukethe i-magnesium, i-aluminium noma i-iron, avimbela ukufakwa kwento esebenzayo ekhulunywa ngayo. Lapho uhlanganiswe, gcina ukuhlangana okungamahora ama-2 phakathi kwemithamo.
Umuthi ukhulisa umphumela we-anticoagulants ngomlomo kanye nobungozi bezidakamizwa ezilwa nokuvuvukala (okungeyona i-steroidal).
I-Probenecid ivimbela ukuqedwa kwe-lomefloxacin emzimbeni.
Ukuhambisana notshwala
Umenzi akancomi ngokuqinile ukuhlanganisa umuthi neziphuzo eziqukethe i-ethanol.
Ungangena kanjani esikhundleni
Okushibhile kakhulu kwe-MS:
- Lefoksin;
- I-Leflobact;
- Iqiniso;
- Hayleflox;
- I-Syphlox.
Imibandela yekhefu lekhemisi
Ngingakwazi ukuthenga ngaphandle kadokotela
Ungawathenga amaphilisi ngokuya ngencwadi kadokotela.
Intengo yeLomflox
Izindleko zamathebulethi ziyehlukahluka kuluhlu lwama-ruble angama-460-550. kwephakethe No. 5.
Izimo zokugcina zomuthi
Ngokugcina umuthi, indawo engafinyeleleki ezilwaneni nasezinganeni lapho ukukhanya nomswakama kungangeni khona kufanele.
Isikhathi sokuphelelwa yisikhathi
Iminyaka emithathu
Umkhiqizi
I-Ipka Laboratories, Ltd. (India).
Ukubuyekezwa mayelana neLomflox
U-Arina Kondratova, oneminyaka engama-40 ubudala, uChistopol
Lapho ngibamba umkhuhlane, i-bronchitis yami iqala ukwanda. Ngalesi sikhathi, ngiqala ukuphuza ngemishanguzo imishanguzo ehlukene. Ngenxa yalokhu, imishanguzo kufanele ilashelwe. Muva nje, udokotela ubeke la maphilisi. Bathuthukisa isikhundla sami. Manje ngizohlala ngizisebenzisa lapho lesi sifo siphinda sibanjwa ngokungazelele.
UVictor Skornyakov, oneminyaka engama-45, uKazan
Kungekudala kakhulu ngagijimela kuhlobo oluthile lokutheleleka. I-Rhinitis, ukukhwehlela, ukuthimula kanye nomuzwa wokuqubuka okujwayelekile. Udokotela weluleke ukuzama lesi sidakamizwa. Emaphutheni, ngithanda ukugqamisa kuphela ukuthi ngenkathi ngiphuza amaphilisi akufiseleki ukushayela imoto.
