I-Irbesartan umuthi osetshenziselwa ukwelapha umfutho wegazi ophakeme. Ikhiqizwa ngendlela yamathebulethi. Ngaphambi kokusebenzisa, bonisana nodokotela; ukuzelapha kungaba yingozi empilweni nasempilweni yesiguli.
Igama Lezwe elingafanele
Umuthi ubizwa nge-Irbesartan (INN).
I-Irbesartan umuthi osetshenziselwa ukwelapha umfutho wegazi ophakeme.
I-ATX
Ikhodi yezidakamizwa yi-C09CA04.
Khipha amafomu nokwakheka
Umuthi uyatholakala ngesimo samaphilisi e-biconvex wombala omhlophe. Ijamo liyindilinga. Okuphezulu okuhlanganiswe nge-sheath yefilimu.
Umuthi osebenzayo yi-irbesartan hydrochloride, okuyi-1 pc. iqukethe ama-75 mg, ama-150 mg noma ama-300 mg. Abahambeli - i-microcrystalline cellulose, i-magnesium stearate, i-colloidal silicon dioxide, i-povidone K25, i-lactose monohydrate, i-sodium ye-croscarmellose.
Isenzo se-Pharmacological
Umuthi uvimbela isenzo se-angiotensin 2 kuma-receptors atholakala ohlelweni lwezinhliziyo nezinso. Umuthi ungumenzeli we-hypotensive. Yenza umfutho wegazi ekujikelezeni kwe-pulmonary ephansi, yehlisa ukumelana okuphelele kwekhompiyutha. Ibambezela ukukhula kokwehluleka kwezinso.
I-Pharmacokinetics
Ukungeniswa ngokushesha yi-60-80%. Ngemuva kwamahora ama-2, ukunakwa okuphezulu egazini kuyaphawulwa. Inani elikhulu lento lihlangana namaprotheni. I-enzelwe esibindini, ekhishwa yi-80% ngalo mzimba. Okucasulwe yingxenye yezinso. Kuthatha amahora angama-15 ukususa umuthi.
Izinkomba zokusetshenziswa
Umuthi unqunyelwe ukwelashwa kwe-antihypertensive. Isetshenziselwa i-arterial hypertension kanye nephropathy yesifo sikashukela.
Contraindication
Umuthi awubekelwe izingane ezingaphansi kweminyaka engu-18 ubudala, ngoba ukusebenza ngempumelelo nokuphepha kwalo muthi okulesi sikhathi kungaphenywa. Ayisebenzi kwi-hypersensitivity kuzakhi, ngesikhathi sokubeletha kwengane ngenkathi uncelisa ibele. I-contraindication ehlobene ne-aortic noma i-mitral valve stenosis, i-renal stenosis, isifo sohudo, ukugabha, i-hyponatremia, ukomisa, kanye nokwehluleka kwenhliziyo okuhlala njalo.
Ungayithatha kanjani irbesartan?
Amacwecwe athathwa ngomlomo ngaphambi kokudla noma ngesikhathi sokudla. Ukwelashwa kuqala ngo-150 mg ngosuku. Kamuva, umthamo wenyuka waba ngu-300 mg ngosuku. Njengoba ukwanda okuthe xaxa komthamo kuholela ekunyukeni komphumela, ukusetshenziswa kanyekanye nge-diuretics kunqunyelwe. Abantu asebekhulile abanenkinga yokuphelelwa ngamandla emzimbeni futhi behlelwa yi-hemodialysis banikezwa umthamo wokuqala wama-75 mg ngosuku, ngoba kungenzeka ukuthi kuqhamuke i-arterial hypotension.
Ngokuhluleka kwe-renal, kuyadingeka ukulawula izinga le-creatinine egazini, ukugwema i-hyperkalemia.
Nge-cardiomyopathy, kufanele kuqashelwe, ngoba kunamathuba amaningi okuqanjwa kwe-myocardial infarction.
Ngoshukela
Kuhlobo 2 lwesifo sikashukela, umuthi usetshenziswa ekwelapheni inhlanganisela.
Imiphumela emibi ye-Irbesartan
Ezinye iziguli zisabela kabi emithini. IHepatitis, hyperkalemia kungenzeka. Kwesinye isikhathi ukusebenza kwezinso kukhubazeka, emadodeni - ukungasebenzi ngocansi. Izinga lokushisa lesikhumba lingakhuphuka.
Amapheshana wesisu
Isicanucanu, ukugabha kungenzeka. Kwesinye isikhathi kuba nombono osontekile wokunambitha, isifo sohudo, ukushisa kwenhliziyo.
Isistimu yezinzwa ephakathi
Umuntu ukhathala ngokushesha, angahlushwa isiyezi. Ubuhlungu bekhanda bujwayelekile.
Kusuka ohlelweni lokuphefumula
Ubuhlungu besifuba, ukukhwehlela kungavela.
Kusuka ohlelweni lwezinhliziyo
Mhlawumbe ukubonakala kwesifo senhliziyo, i-tachycardia.
Kusuka ohlelweni lwe-musculoskeletal
Ubuhlungu bemisipha, myalgia, arthralgia, cramps kuvela.
Allergies
Ezinye iziguli ziphawula ukwenzeka kokungezwani komzimba: ukulunywa, ukuqubuka, i-urticaria.
Umthelela ekhonweni lokulawula izindlela
Ngenxa yokubonakala kwesiyezi, kunconywa ukwenqaba ukushayela imoto phakathi nokwelashwa.
Imiyalo ekhethekile
Amanye amaqembu eziguli kufanele aphuze umuthi ngokuqapha.
Sebenzisa ebudaleni
Iziguli ezineminyaka engaphezu kwengu-75 ubudala zinikezwa imithamo ephansi ukugwema izinkinga ezingaba khona.
Ukunquma i-Irbesartan ezinganeni
Kuze kube iminyaka engu-18, umuthi awuchaziwe.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Abesifazane abakhulelwe nabomama abancelisayo abavunyelwe ukuthatha umuthi.
Ukweqisa kwe-Irbesartan
Uma kwenzeka kweqa ngokweqile, i-tachycardia noma i-bradycardia, ukuwa, kanye nokwehla komfutho wegazi kuyaphawulwa. Isisulu kufanele sithathe amalahle ocushiwe, hlamba isisu, bese siqhubeka nokwelashwa okubonakalayo.
Ukuxhumana nezinye izidakamizwa
Kuyadingeka ukwazisa udokotela ngayo yonke imithi esetshenzisiwe: ezinye izinhlanganisela zingaba yingozi empilweni nasempilweni. Kwezinye izimo, ukusetshenziswa kanyekanye ne-hydrochlorothiazide kuyakhonjiswa.
Inhlanganisela ehlanganisiwe
Inhlanganisela enqatshelwe ne-ACE inhibitors ku-nephropathy yesifo sikashukela. Iziguli ezinesifo sikashukela ziyafakelwa ekusebenziseni kanyekanye kwezidakamizwa eziqukethe i-aliskiren. Kwezinye iziguli, inhlanganisela enjalo idinga ukuqashelwa.
Akuhlanganisiwe ukuhlanganisa
Akunconywa ukuhlanganisa namalungiselelo aqukethe i-potassium. Mhlawumbe ukwanda kwenani lezinto zokulandela umkhondo egazini.
Inhlanganisela edinga ukuqashelwa
Akunconywa ukuhlanganisa nokuthatha izidakamizwa eziqukethe i-lithium. Sebenzisa ngokuqapha kanyekanye ne-diuretics nezinye izidakamizwa ze-antihypertensive ukugwema umsebenzi we-renal ophazamisekile.
Ukuhambisana notshwala
Ukuhlanganisa ukwelashwa nokusetshenziswa kophuzo oludakayo akunconywa, ngoba ubungozi bemiphumela emibi nezinkinga ziyanda.
Ama-Analog
Umuthi une-analogues, bomcondvofana. Ukusebenza kahle kubhekwa njenge-Aprovel. Ngesisekelo se-medoxomil olmesartan, iCardosal iyenziwa. Amanye ama-analogues - uTelmisartan, uLosartan. Umuthi i-Azilsartan ungasetjenziswa, into esebenzayo lapho kusetshenziswa khona i-azilsartan medoxomil. Odokotela banquma ukusetshenziswa kwe-Irbesartan Canon kwezinye iziguli.
Imibandela yekhefu lekhemisi
Umuthi ungathengwa kuphela ngemithi kadokotela.
Intengo ye-Irbesartan
E-Russia, ungathenga umuthi ngama-ruble angama-400-575. Izindleko ziyahlukahluka kuye ngamakhemisi, esifundeni.
Izimo zokugcina zomuthi
Gcina kwiphakheji yasekuqaleni emazingeni okushisa angama- + 25 ... + 30 ° C endaweni eyomile futhi emnyama lapho izingane zingafinyeleleki khona.
Isikhathi sokuphelelwa yisikhathi
Umuthi ufanele iminyaka emi-2 kusukela ngosuku lokukhiqizwa, emva kwalokho okufanele uchithiwe.
Umkhiqizi
Umuthi ukhiqizwa nguKern Pharma S. L., Spain.
Ukubuyekezwa ku-Irbesartan
UTatyana, oneminyaka engama-57, uMagadan: "Udokotela ubeke umuthi wokwelashwa i-nephropathy yesifo sikashukela. Ngawuthatha ngomuthi olungiselelwe ngokwendlela ebekiwe. Ngangiqala ukuzizwa ngingcono. Emithini yokuphuza, sengingabiza izindleko eziphakeme zomuthi kanye nesiyezi ngemuva kokuwuphuza."
UDmitry, oneminyaka engama-72, uVladivostok: "Ebusheni bakhe, wahlaselwa umfutho wegazi ophakeme, isimo sakhe saqala ukuba sibi kakhulu ngeminyaka: kwavela i-tinnitus, ikhanda elibuhlungu ekhanda. Kuqala wahlupheka, kepha wabe eseya kudokotela. Udokotela wanquma ukwelashwa no-Irbesartan. Inyanga. Isimo sazinza, kepha kwaphinde kwacindezela ingcindezi. Udokotela wathi uyisebenzisa njalo. Waqala ukuzizwa engcono. Izindaba ezimnandi ukuthi intengo, yize incane, kepha hhayi iphakeme kakhulu. "
U-Ludmila, oneminyaka engama-75, uNizhny Novgorod: "Bekumele ngibone i-Therapist ngenxa yengcindezi yokucindezela. Udokotela waqoqa umuthi. Zonke izinsuku ngithatha i-1 ithebhulethi yokuvimbela, kuyasiza kahle. Ingcindezi ibuyele kwesejwayelekile, futhi ukuthembela esimweni sezulu kuye kwanyamalala. Ngiyancoma. "
