Le yi-penicillin yokwenziwa, esebenza kahle eqenjini elikhulu lama-microorganisms we-pathogenic, kepha ayisebenzi elusizo ekuthelelekeni ngegciwane nasegciwane.
Igama Lezwe elingafanele
I-Amoxicillin (Amoxicillin).
Le yi-penicillin yokwenziwa, esebenza kahle eqenjini elikhulu lama-microorganisms e-pathogenic.
I-ATX
Ngokwesihlukaniso se-anatomical, zokwelapha kanye namakhemikhali, i-amoxicillin ifakiwe eqenjini le-J01CA - "Broad-spectrum penicillins."
Khipha amafomu nokwakheka
Umuthi uyatholakala ngesimo se-powder yokulawulwa komlomo kanye nokulungiswa kokumiswa okufakwa ku-vial ye-100 ml ngemiyalo yokusetshenziswa. Umuthi ulahlekelwa yizinto zawo zokuphulukisa ngendlela yesisombululo, ngakho-ke ukumiswa kuyatholakala ngendlela yama-granules a-soluble.
Ukwakheka kwalesi sidakamizwa kufaka i-amoxicillin ngesimo se-trihydrate.
Isenzo se-Pharmacological
I-Amoxicillin 125 iyinhlangano elwa namagciwane engenziwayo enesibuko esikhulu somsebenzi we-antimicrobial. Lithinta ngempumelelo ama-bacteria amaningi we-gram-negative ne-gram-positive, ikakhulukazi i-aerobic streptococci, staphylococci, gonococci, meningococci, salmonella, Escherichia coli, Pfeiffer coli nabanye.
I-Pharmacokinetics
Amahora angama-1-2 ngemuva kokuphathwa, afinyelela ekugxambeni okuphezulu ku-plasma yegazi futhi angena ezicutshini nasemanzini omzimba. Ukudla okwanele akuphazamisi ukufakwa kwesidakamizwa emzimbeni. Iqongelela kumchamo, emaphashini, kwisinye inyongo, uketshezi lwe-peritoneal, i-oblium emabhulashini, mucosa wamathumbu, izitho zokuzala zabesifazane. Kucutshungulwa ngokwengxenye futhi kudalulwe izinso nesibindi. Inani elincane likhishwa ubisi lwebele.
Ingxenye yempilo yento ivela emaminithini angama-60 kuye kwangama-90.
Izinkomba zokusetshenziswa
Njenganoma yiluphi umuthi olwa namagciwane, i-Amoxicillin imiselwe izifo ezibangelwa ama-microorganisms alula, kubandakanya:
- izifo zokuphefumula zamapheshana wokuphefumula (inyumoniya, isifo sezinsini ezingapheli ngesikhathi sokuqhuma, imithombo yezindaba ye-otitis, i-pharyngitis, i-tonsillitis, i-sinusitis);
- ukutheleleka kwezinso nepheshana lomchamo (cystitis, pyelitis, pyelonephritis, urethritis);
- i-gonorrhea;
- chlamydia, kufaka phakathi ukungabekezelelani kwe-erythromycin ngesikhathi sokukhulelwa;
- i-cervicitis;
- izifo zesikhumba: ama-dermatoses, impetigo, erysipelas;
- ukutheleleka kwe-musculoskeletal;
- pasteurellosis;
- i-listeriosis;
- ukutheleleka kohlelo lokugaya: isalmonellosis, typhoid, dysentery;
- ukuvimbela kanye nokwelashwa kwe-endocarditis.
Contraindication
Ukwemukelwa kwenqatshelwe ngokwanda kokuthola i-amoxicillin namanye ama-penicillin ne-cephalosporins, ene-mononucleosis ethelelekayo, i-lymphocytic leukemia, ukwehluleka kwesibindi, izifo zesistimu yokugaya ukudla (i-colitis ekwelashwa ngama-antibiotic).
Ngokunakekela
Ngokuqapha, umuthi ubekelwe ukuphathwa ezigulini ezibangelwa yi-allergies (i-asthma ye-bronchial, i-hay fever), ukwehluleka kwezinso, umlando wokukopha nokukhulelwa.
Ungayithatha kanjani i-Amoxicillin 125
Umuthi kumele udliwe izikhathi ezi-3 ngosuku njalo ngamahora angama-8 ukuqinisekisa ukutholwa njalo komthamo wamanje we-antibiotic. Abantu abadala nezingane kusuka eminyakeni eyi-12 ubudala (enesisindo somzimba esingaphezu kwamakhilogremu angama-40), umthamo ojwayelekile wosuku ngu-500 mg kathathu ngosuku.
Ngaphambi noma ngemuva kokudla
Noma lokhu kudla kungawuthinti umphumela wokwelashwa, umuthi akufanele uphuzwe esiswini esingenalutho kwiziguli ezinesifo sohlelo lokugaya ukudla: i-gastritis ene-asidi ephansi noma ephezulu, i-enterocolitis, ukuqunjelwa noma isifo sohudo, i-dysbiosis noma isilonda sesisu noma isisu esincane.
Zingaki izinsuku zokuphuza
Ngokwesilinganiso, isikhathi sokwelashwa sisukela ezinsukwini ezi-5 kuye kwezingu-12. Ngemuva kwalokhu, udinga ukuyeka futhi uphinde uqhubeke kuphela ekuncomweni kukadokotela.
Esikhathini sikashukela, ukungavikeleki kweziguli kuncishisiwe, ngakho-ke umzimba usengozini enkulu yokutheleleka.
Ukuthatha umuthi wesifo sikashukela
Esikhathini sikashukela, ukungavikeleki kweziguli kuncishisiwe, ngakho-ke umzimba usengozini enkulu yokutheleleka. Imvamisa, imithi elwa namagciwane ibekelwa izifo zesikhumba, i-urethra nepheshana lokuphefumula eliphansi. Sebenzisa umuthi ngokuqapha, kuphela ngaphansi kokuqondisa udokotela futhi kuphela ezimweni lapho kunengozi ye-hypoglycemia.
Imiphumela emibi
Ngenxa yokuthi ama-penicillin athinta i-microflora yamathumbu futhi alayishe umzimba, isiguli singathola ukungaphatheki kahle ezinhlakeni ezihlukene zesitho ngesikhathi sokwelashwa.
Amapheshana wesisu
Umuthi ungadala izinhlobo ezilandelayo zokuphendula:
- dysbiosis;
- i-stomatitis
- i-gastritis;
- umlomo owomile
- Ubuhlungu ku-anus;
- ushintsho ekunambithekeni;
- Ubuhlungu besisu
- isicanucanu nokuhlanza
- isifo sohudo
- glossitis;
- ukuphazamiseka kwesibindi.
Isistimu yezinzwa ephakathi
Kungabonakala:
- ukwethuka (ngomthamo owandayo womuthi);
- ukuthuthumela
- ikhanda.
Kusuka ohlelweni lwezinhliziyo
Ayikhishwa:
- i-tachycardia;
- i-anemia
- i-leukopenia.
Allergies
Ngomzwa okhulayo wokuzwa, ukungezwani komzimba kungenzeka: i-hyperemia yesikhumba, i-urticaria, ukulunywa kanye nokuqothuka kwe-epermermis, i-rhinitis, i-conjunctivitis, i-edema ye-Quincke, kaningi kakhulu - umkhuhlane, isikhumba esibuhlungu kakhulu, isifo se-Stevens-Johnson. Akuvamile - ukwethuka kwe-anaphylactic.
Umthelela ekhonweni lokulawula izindlela
Azange kube nezifundo eziyisipesheli zemitholampilo mayelana nomphumela we-Amoxicillin emandleni okushayela izimoto nokuphatha izindlela eziyinkimbinkimbi.
Imiyalo ekhethekile
Ngesikhathi sokulashwa, ukunakwa okukhethekile kufanele kukhokhwe esimweni sesibindi nezinso.
Iziguli ezine-penicillin hypersensitivity zingathola ukusabela kwe-cross-allergic ngemithi elwa namagciwane e-cephalosporin.
Uma ngesikhathi se-Amoxicillin kunesidingo sokulapha isifo sohudo esithambile, kungcono ukungasebenzisi izidakamizwa ezinciphisa i-peristalsis. I-Attapulgite noma i-kaolin equkethe imithi ingasetshenziswa.
Ukwelashwa kuthatha amahora angama-48-72 ngemuva kokunyamalala kwezimpawu zangaphandle zesifo.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Ukusetshenziswa kuvunyelwe kuphela uma inzuzo kumama idlula engcupheni yengane. Njengoba ama-penicillin angena ebisini futhi engaphatha ukonakala kwesisu sengane namathumbu, sebenzisa lesi sidakamizwa ngokuqapha ngesikhathi sokuqunjelwa.
Sebenzisa ebudaleni
Ekwaluphaleni, umthamo ufana nalowo unconyelwe iziguli ezindala, ukulungiswa kwenani lemithi akudingeki.
Ungayinikeza kanjani i-Amoxicillin ezinganeni eziyi-125
Umthamo wansuku zonke wezingane uhlukaniswe ngemithamo engu-4-6 futhi unqunywa yiminyaka yokuhambisana nesisindo somzimba:
- kusuka enyangeni eyi-1 - 150 mg nge-1 kg;
- kuze kube unyaka 1 - 100 mg nge-1 kg;
- Iminyaka engu-1-4 - 100-150 mg nge-1 kg;
- kusuka eminyakeni engu-4 - 1-2 g.
Umthamo wansuku zonke wezingane unqunywa ubudala obuhlobene nesisindo somzimba.
Isikhathi sokwelashwa sinqunywa ubukhali besi sifo (kusuka ezinsukwini ezi-5 kuye kwezingu-20). Kwezifo ezingamahlalakhona, ukwelashwa kungathatha izinyanga ezimbalwa.
Ukulungiselela ukumiswa, engeza amanzi abilisiwe ahlanganiswe ebhodleleni le-powder kumaki, bese unikina kahle. Ngaphambi kokusebenzisa, uzodinga ukushukumisa ukumiswa futhi. Umthamo wenziwa ngenkomishi yokulinganisa.
Isicelo sokusebenza kokulimala kwezinso
Uma kwenzeka kuphazamiseka ukusebenza kwe-renal, i-Amoxicillin ichazwa ihlanganiswa ne-clavulanic acid (isidakamizwa i-Amoxiclav). Le nhlanganisela ivimba ukukhula kwegciwane elinegciwane.
Ukweqisa
Izimpawu eziphambili ze-overdose zifaka: isifo sohudo, isicanucanu kanye nokuhlanza, okuholela ekwephulekeni kokulingana kwe-electrolyte.
Lapho kuboniswa izimpawu zobuthi obunobuthi nge-Amoxicillin, kuyadingeka ukwenza ngokwendlela elandelayo:
- Hlanza isisu ngamanzi afudumele, angcolile.
- Thatha umthamo odingekayo we-adsorbent (i-carbon eyenziwe isebenze ngesilinganiso sethebhulethi eyi-1 nge-10 kg yesisindo somzimba).
- Thatha i-saline laxatives.
- Izinsalela ze-antibiotic zidlulwa yi-hemodialysis.
Uma kwenzeka kuphazamiseka ukusebenza kwe-renal, i-Amoxicillin ichazwa ihlanganiswa ne-clavulanic acid (isidakamizwa i-Amoxiclav).
Ukuxhumana nezinye izidakamizwa
Ukwehla nokwehla kwembangela yokufaka:
- i-glucosamine;
- ama-antacid;
- ama-laxatives;
- ukudla.
Kwandisa ukumunca kwe-ascorbic acid.
Ukuqina okuhlanganisiwe komphumela kwenzeka lapho uthatha ama-bactericidal antibacterial (Rifampicin, aminoglycosides).
I-Amoxicillin yenza buthaka i-tetracyclines, i-sulfonamides, i-chloramphenicol.
Igqamisa umphumela we-anticoagulants engaqondile.
Iwenza buthaka umphumela wokuvimbela inzalo okuqukethe i-estrogen.
Kwandisa ubuthi be-methotrexate.
Ngcono ukumunca kwe-digoxin.
I okuhlushwa umuthi kwandisa ijovo ehlanganyelwe:
- nge-diuretics;
- nge-non-steroidal anti-inflammatory;
- nge-phenylbutazone;
- nge-oxyphenbutazone.
I-Allopurinol inyusa ingozi yokuqhuma kwesikhumba.
Ukuhambisana notshwala
Ukuhambisana kwesiphuzo esinezidakamizwa ne-ethanol asikho. Ngesikhathi sokulashwa nge-Amoxicillin, kungcono ukwenqaba utshwala: ukuhoxa kwalezi zinto zombili kwenzeka ngezinso nesibindi. Lapho uthatha utshwala, isibindi siqala ukukhiqiza ama-enzyme okwakha umzimba i-ethanol. Ukusetshenziswa okuhlangene kwe-Amoxicillin notshwala kuthuthukisa ubuthi bamuva futhi kungaholela ekufiseni ubuthi be-ethanol, okucasula kakhulu ulwelwesi lwe-mucous lwesisu namathumbu amancane. Ngaphezu kwalokho, utshwala buthaka umphumela we-antibacterial womuthi, ngakho-ke ukuphathwa kwabo ngasikhathi sinye kungabandakanywa.
Ama-Analog
Kumakhemisi, kunezinhlobo eziningi zamagama aseRussia nawangaphandle aphathelene nomuthi, athengiswa amanye amagama. Amanani, ikakhulukazi izidakamizwa ezingeniswa, aphezulu kakhulu kunawangempela. Phakathi kwezinto ezenziwa ngogesi:
- I-Azithromycin Amandla wokumiswa. Ukunakekelwa okukhulu kufanele kuthathwe: lesi sidakamizwa sinohlu olubanzi kakhulu lwe-contraindication.
- I-Ecobol. Kutholakala ezibhebheni. Kusetshenziswa ezimweni ezifanayo nezasekuqaleni. Ihlanganiswe ezinganeni ezingaphansi kweminyaka engu-3. Kunqunyelwe ngokuqapha kwabesifazane abakhulelwe nabomama abancelayo, ngokwehluleka kwezinso.
- Amose. Ingathathelwa izingane ezingaphansi kweminyaka emi-2 ubudala, ngokuya ngesilinganiso esidingekayo.
- Flemoxin (Amoxicillin) Solutab (500 mg). Uzakwabo waseDashi. Kuyatholakala ngesimo sethebhulethi. Ivinjelwe izingane.
- I-Amoxiclav. Ukuhlanganiswa kwe-amoxicillin (875 mg) ne-clavulanic acid (125 mg). Kutholakala ngesimo samathebulethi ne-powder wokwenza ukumiswa. Ithuluzi elithandwa kakhulu futhi livame ukutholakala ethendeni lamakhemisi. Ngesikhathi esifanayo kuyabiza.
Amoxicillin 125 izimo zokuhambisa ezivela ekhemisi
Ngokusebenzisa umuthi. Umuthi kufanele ukhombise igama lesiLatini lomuthi (i-Amoxycillinum) nenketho yokukhishwa.
Ngingakwazi ukuthenga ngaphandle kadokotela
Kusukela ngo-2017, uhlu lwama-antibiotic oluzothengiswa kuphela ngomuthi kadokotela obuyele lolo lolo luphinde lwenziwa kabusha nge-Amoxicillin, ngakho-ke cishe akunakwenzeka ukukuthenga ngokukhululeka, ngaphandle kokuthola umuthi.
Amoxicillin 125 intengo
Lesi sidakamizwa esishibhile: uhla lwamanani lusuka kuma-ruble angama-40 kuye kwangama-200. Ama-Analogs angabiza okuningi.
Izimo zokugcina zomuthi
I-powder igcinwa emazingeni okushisa aze afike ku-25 ° C. Ukumiswa okulungiselelwe kufanele kugcinwe kude nezingane ngokushisa kwe + 2 ... + 8 ° C futhi kudliwe isonto lonke.
Isikhathi sokuphelelwa yisikhathi
Iminyaka emi-3 kusukela ngosuku lokukhishwa.
Umkhiqizi Amoxicillin 125
Umuthi okwenziwa ngawo impuphu uyenziwa futhi uhanjiswe esifundeni saseRussia kanye nasemazweni e-CIS yinkampani yemithi yaseChina uHuabei.
Ukubuyekezwa kodokotela neziguli ku-Amoxicillin 125
U-Ekaterina, oneminyaka engama-27 ubudala, e-Ekaterinburg
Umuthi ubekelwe ingane ngemuva kokuhlolwa komoya wokuphefumula kweHelicobacter pylori. Kwamiswa imishanguzo emi-2, eyodwa yayo yi-Amoxicillin. Kwakudingeka ukuthatha ithebhulethi kathathu ngosuku, kanye neminye imithi ngemuva kokudla. Isifiso sokudla kwengane sehlile kancane, kepha ukululama kwenyuka ngokushesha. Welapha lesi sifo, kepha anciphisa ukungaziguli, ikakhulukazi ezinganeni. Sebenzisa ngokuqapha.
U-Eleanor, oneminyaka engama-33, eMoscow
Waqala ukuphuza ama-antibiotic ngenxa yokubanda okuvamile ebusika: wayenomkhuhlane, impumulo egeleza, ikhanda, futhi waqala ukuvimba izindlebe zakhe. Uchwepheshe we-ENT uthole i-sinusitis esigabeni esibuhlungu (esingamahlalakhona, kepha asenzekanga kaningi) nabezindaba ze-otitis. I-Amoxicillin ebekiwe, iSanorin yakhala neRemantadine neComplivit ukuqinisa ukungatheleleki komzimba.
Bona i-antibiotic kathathu ngosuku. Ngosuku olulandelayo kwaba ngcono, sahamba kancane. Izindlebe azilimazi, kepha ikhanda liba nzima uma ugoba ngaphezulu. Ngemuva kwezinsuku ezi-2, induna yathululelwa ebusweni nase esifubeni. Kepha i-sinusitis ne-otitis yelashwa. Umuthi odidayo, njengawo wonke ama-antibiotic.
I-Kurbanismailov RB, Krasnoyarsk, udokotela wezifo zabesifazane
I-antibiotic enhle engabizi kakhulu edingekayo phakathi kodokotela baseRussia. Kunama-generics amaningi avame ukusetshenziswa kwi-gynecology ukuvikela izifo. Ukuvela komzimba kwenzeka kakhulu. Kutholakala kalula emakhemisi.
Budanov E.G., Sochi, otolaryngologist
I-antibiotic ejwayelekile ingumbukiso obanzi owenziwe ngesigamu. Yemukelwa kahle ngumzimba, ifomu elilungele ukusetshenziswa, ikakhulukazi izingane. Ivame ukusetshenziselwa ukutheleleka kwe-streptococcal kanye nezifo ezinzima zepheshana lokuphefumula eliphezulu. Ngemuva kokusebenzisa ezinye izidakamizwa ezilwa namagciwane, kuba buthakathaka kunalokho. Kwesinye isikhathi kungadala ukungezwani komzimba. Kuhle ukuyisebenzisa ekwelapheni i-tonsillitis ne-pharyngitis.