Amacwecwe e-Berlition asetshenziselwa ushukela, ukudambisa izimpawu ze-neuropathy kanye nezindlela ezahlukahlukene zokuphuza (kufaka notshwala). Imiyalo yokusebenzisa iqukethe yonke imininingwane edingekayo, ngakho-ke udinga ukuyifunda ngokucophelela ngaphambi kokuthatha umuthi.
Igama Lezwe elingafanele
I-Thioctic acid.
Amacwecwe e-Berlition asetshenziselwa ushukela, ukudambisa izimpawu ze-neuropathy kanye nezindlela ezahlukahlukene zokuphuza (kufaka notshwala).
I-ATX
I-A16AX01.
Ukwakheka
Ithebhulethi ngayinye iqukethe ama-300 mg ento esebenzayo (alpha lipoic / thioctic acid). Ukwakheka Okusizayo:
- i-hydrate i-silicon dioxide;
- i-croscarmellose sodium;
- I-MCC;
- i-magnesium stearate;
- i-monohydrogenated lactose.
Okuqukethwe kuqukethe izinto ezinjalo:
- uphalafini uketshezi;
- i-sodium lauryl sulfate;
- I-E171;
- i-hypromellose;
- udayi "ilanga" (ophuzi - E110).
Isenzo se-Pharmacological
Ingxenye esebenzayo (i-thioctic α-lipoic acid) iyi-antioxidant ye-endo native. Kubonakala emzimbeni ngenxa yezinqubo ze-oxidative-decarboxylated ze-alpha-keto acid.
Umuthi wehlisa ukugcwala kwe-glucose futhi uvuselele izinga le-glycogen ezakhiweni zesibindi.
Isiza ukubhekana nokuphikisana ne-insulin. Ngokuphathelene nemiphumela ye-biochemical, i-compact iyafana no-Vitamin B. Ngokwengeziwe, i-alpha-lipoic acid ibandakanyeka ku-metabolism ye-carbohydrate kanye ne-lipids, ithuthukisa i-cholesterol metabolism kanye nokusebenza kwesibindi / kwesibindi.
Umuthi ubonakala nge-hypoglycemic, hypocholesterolemic, hypolipidemic nomsebenzi we-hepatoprotective.
I-Pharmacokinetics
I-Alpha lipoic acid ngokuphelele futhi imunca ngokushesha ukwakheka kwendlela yokugaya. Ukudla kunciphisa izakhiwo zokufakwa kwento. I-Cmax ifinyelelwa kungakapheli imizuzu engama-45-65.
Ingxenye “inendima eyinhloko” yezicubu zesibindi.
Ama-Metabolites (asebenzayo) akhiwa ngenxa yezinqubo zokuhlangana kanye nokuphendula okuvela ku-oxidative ekwakhiweni kwecala eliseceleni.
I-80-90% yento iyakhululwa ngesikhathi sokuchama. I-T1 / 2 ebangeni eliyimizuzu engama-20 kuye kwengama-50. Ukukhishwa okuphelele kwento ku-plasma yegazi kufinyelela ku-10-15 ml ngomzuzu.
Izinkomba zokusetshenziswa
Umuthi ubekelwe ukwelashwa kwezindlela ezinotshwala / zesifo sikashukela se-polyneuropathy, i-fat dyibindi yesibindi kanye nokudakwa okungalapheki.
Umuthi ubekelwe ukwelashwa kwefomu lesifo sikashukela se-polyneuropathy.
Contraindication
Contraindication:
- ukuncelisa;
- ukukhulelwa
- ukusabela kokungezwani nokwakheka kwezidakamizwa;
- ebusheni nasebuntwaneni.
Ungawathatha kanjani amaphilisi we-Berlition
Esiswini esingenalutho (isigamu sehora ngaphambi kokudla), ngaphakathi. Isikhathi inkambo yokwelashwa incike izinkomba futhi ichazwe uchwepheshe ngamunye.
Kwabadala
Iziguli zabantu abadala zinikezwa amaphilisi ama-2 (600 mg) kanye ngosuku.
Okwezingane
Akubhaliwe ngaphandle.
Ngoshukela
Iziguli ezinesifo sikashukela zidinga ukuqashwa njalo kwe-plasma glucose. Ukulungiswa komthamo we-insulin kuyadingeka.
Imiphumela emibi yamathebulethi we-Berlition
Izitho zeHematopoietic
- i-phenura (i-hemorrhagic rash);
- i-thrombocytopenia;
- thrombophlebitis.
Isistimu yezinzwa ephakathi
- ukubonakaliswa okukholisayo;
- amadiplopian uthi;
- ukonakala kokunambitheka / ukuhogela;
- isiyezi esincane.
Ngasohlangothini lwe-metabolism
- ushukela okhubazekile;
- ukujuluka
- hypoglycemia
Allergies
- i-anaphylaxis (ezimweni ezivamile kakhulu);
- isikhumba esikhanyayo;
- ukuqhuma okuncane;
- ukuvuvukala.
Umthelela ekhonweni lokulawula izindlela
Ngokusebenzisa i-MP futhi uhlanganyele emsebenzini odinga ukunakwa nokusabela okusheshayo, kudingeka ukuqapha.
Imiyalo ekhethekile
Kunconywa ukusebenzisa ubisi, i-kefir neminye imikhiqizo yobisi, kanye nokuthatha amalungiselelo e-iron ne-magnesium ngesikhathi sokwelashwa ngemuva kwasemini.
Ngesikhathi sokulashwa ngomuthi, kunengozi yokungalingani kwe-acid-base.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Kuqinisekisiwe.
I-Overdose yamathebulethi we-Berlition
Lesi simo sihambisana nokunxenxa ukuhlanza nokukhanda. Ukwelashwa kwezimpawu kunconyiwe
Ukuxhumana nezinye izidakamizwa
Ukuhlanganiswa kwamathebhulethi ane-cisplatin kunciphisa ukusebenza kwawo kwemithi.
I-Alpha lipoic acid inamandla okubopha ushukela, yakha izinto eziyinkimbinkimbi ezingambi kahle. I-MP inyusa umphumela we-hypoglycemic wanoma iyiphi i-hypoglycemic.
Ukuhambisana notshwala
Ama-ejenti aqukethe utshwala kufanele ashiywe sonke isikhathi sokwelashwa, ngoba i-ethanol imthelela omubi umphumela we-alpha-lipoic acid.
I-overdose yamathebhulethi we-Berlition ihambisana nokuhlanza.
Ama-Analog
Izidakamizwa ezingezansi:
- Neuroleipone;
- I-Thioctacid;
- I-Thiolipone (isisombululo sokulungiselela ukumiselwa kokuphathwa kwe-intravenous ku-ampoules);
- I-Thiogma (ngesimo samaphilisi);
- Espa Lipon.
Imibandela yekhefu lekhemisi
Ngingakwazi ukuthenga ngaphandle kadokotela
Ukuthenga izidakamizwa ekhemisi, udinga ukuletha incwadi kadokotela.
Intengo
E-Russia, amaphilisi angama-30 ebhokisini lekhadibhodi abiza kusuka kuma-ruble angama-540, e-Ukraine - kusuka ku-140 UAH.
Izimo zokugcina zomuthi
Vikela ekuchayelweni ukukhanya, amazinga okushisa aphezulu kanye nomswakama.
Isikhathi sokuphelelwa yisikhathi
Kufika eminyakeni emi-2.
Umkhiqizi
"Berlin Pharma" (Germany).
Ukubuyekezwa
Odokotela
U-Boris Dubov (owelaphi), oneminyaka engama-40 ubudala, eMoscow
Umuthi usetshenziselwa i-polyneuropathy yesifo sikashukela / i-alcoholic. Unezindlela eziningana zokukhululwa. Uma uhambisana nezincomo nemiyalo, ungakugwema ukusabela okungekuhle. Ngokuvamile kusetshenziswa ku-osteochondrosis njengosizo.
Iziguli
U-Yana Koshayeva, oneminyaka engama-35, uTver
Kwatholakala ukuthi nginesifo sikashukela esibhedlela. Waphoqeleka ukuthi afunde ukulawula ushukela futhi ajwayele ukufaka i-insulin njalo. Kepha muva nje, lesi sifo sihlasele uhlelo lwangaphakathi lwezinzwa. Ukuvimbela izinkinga, udokotela unqume inkambo yokuphuza la maphilisi. Ngibaphuza 1 ngosuku njengekhambi lesondlo. Isimo sakhe saba ngcono, ngisho nemizwa yakhe yaphakama, futhi ukudangala kwanyamalala. Umuthi awuzange ubange nemiphumela emibi futhi awushintshanga amazinga eglucose.
U-Alena Alegrova, oneminyaka engama-39, uVoronezh
Ngiqale ukuphuza amaphilisi ngenxa yesifo sikashukela. Udokotela wachaza ukuthi umuthi uvimbela ukunqwabelana kwe-glucose egazini futhi ubuyekeze isimo esejwayelekile. Kuyabiza, umbuso uyakweseka. Udokotela uncome isifundo sesibili ngemuva kwezinyanga ezi-5-6.
