I-Prevenar umuthi wokugomela okuhloswe ngawo ukuvikela ukutheleleka kwe-pneumococcal ezinganeni ezihlanganiswe neproteyini ethwala i-diphtheria.
Ath
Ikhodi ye-Ath: J07AL02.
I-Prevenar umuthi wokugomela okuhloswe ngawo ukuvikela ukutheleleka kwe-pneumococcal ezinganeni ezihlanganiswe neproteyini ethwala i-diphtheria.
Khipha amafomu nokwakheka
Umuthi uyatholakala ngesimo sokumiswa kwe-homogenible emhlophe ngomjovo. Umuthi wokugoma awuhlangene ngombala ohlukile. Kuvunyelwe imvula enamafu amhlophe ukuba ichitheke, bese inyamalala lapho isitsha sinyakaziswa. Ibhodlela elilodwa liqukethe ama-polysaccharides ama-serotypes alandelayo:
- 4 kuye ku-2 mcg;
- 6B - 4 mcg;
- 9V - 2 mcg;
- 14 kuya ku-2 mcg;
- 19F - 2 mcg;
- 23F - 2mkg.
I-Serotype 18C oligosaccharide - 2 μg, amaprotheni othwala i-CRM 197 - cishe angama-20 μg. Abahambeli: i-aluminium phosphate, i-sodium chloride.
Isenzo se-Pharmacological
Umuthi wokugoma uvuselela ukukhiqizwa kwama-antibodies. Ngenxa yalokho, ingane iba nomzimba ongavikelekile kwi-pneumococcus. Ukugoma kunikeza impendulo yokuzivikela komzimba kuwo wonke ama-serotypes we-polysaccharide.
I-Pharmacokinetics
Umuthi udonswa egazini, uhlinzeka ngokuvikela izinhlobo eziphambili zokutheleleka kwe-pneumococcal. Akukho datha yokuthi izingxenye zomuthi zithuthukiswa kanjani.
Umuthi udonswa egazini, uhlinzeka ngokuvikela izinhlobo eziphambili zokutheleleka kwe-pneumococcal.
Gonywa nini futhi yini
Umuthi wokugomela udluliswa ngendlela efanelekile ukuze kuthuthukiswe ukungatheleleki kokutheleleka nge-pneumococcal. Kuvikela ekuthuthukisweni kwezifo ezilandelayo:
- i-bacterial pneumonia;
- i-bronchitis;
- ezinye izifo ezithathelwanayo zohlelo lokuphefumula;
- abezindaba ze-otitis;
- i-sinusitis ne-sinusitis;
- umphimbo obuhlungu;
- i-meningitis.
Ukugoma kunciphisa izehlakalo zezinkinga ngemuva kwamakhaza.
Amaqembu eziguli alandelayo adinga kakhulu ukugoma:
- Izingane ezizalwe ngaphambi kwesikhathi.
- Izingane zonyaka wokuqala wokuphila.
- Izingane ezihlushwa yizifo ezingamahlalakhona: Isandulela ngculazi, isifo sikashukela, nezinye izifo eziholela ekunciphiseni kokungazinzi kwemvelo.
- Ngokubanda njalo, ukugoma kwenziwa ezinganeni ezingaphansi kweminyaka engu-5.
Ukugoma kunciphisa izehlakalo zezinkinga ngemuva kwamakhaza.
Kukangaki
Inani lemijovo yesidakamizwa lincike eminyakeni yengane:
- Uma ukugoma kuqalwa eneminyaka engu-2 kuya kwayi-6 izinyanga, kwenziwa izigaba ezi-4: eyokuqala engu-3 - ngokuvalwa kwezinsuku ezingama-30, eyokugcina - eneminyaka engu-1 nezinyanga ezi-3.
- Uma ukwelashwa kuqalwa eneminyaka eyi-7 kuya kwayi-11 izinyanga, ukugonywa kabili kwenziwa ngokuphumula kwezinsuku ezingama-30. Umthamo owodwa womuthi uvuselelwa lapho uneminyaka emibili.
- Ngonyaka wokuqala nowesibili wokuphila - imithamo emibili yokugoma, isikhawu izinyanga ezimbili.
- Eminyakeni emihlanu, ukugoma kwenziwa 1 isikhathi.
Kubekezelelwa kanjani
Umuthi ungadala ukukhuphuka okuthe xaxa kwezinga lokushisa nokukhuphuka kancane. Emazingeni okushisa angaphezu kuka-38 ° C, ukukhwehlela, ukucinana kwamakhala, thintana nodokotela.
Kungenzeka yini ngesifo sikashukela
Ngesifo sikashukela, ukugoma kuyenziwa.
Ngesifo sikashukela, ukugoma kuyenziwa.
Kungenzeka yini ukuhamba ngemuva kokugoma
Ezinsukwini ezingama-30 ngemuva kokugoma akumele uxhumane nabaphethe i-pneumococcus. Lapho uthintana nomtholampilo udinga ukugqoka imaskhi evikelayo. Awungeke uye enkulisa. Ngenkathi efudumele, ukuhamba kuvunyelwe. Ebusika, kungcono ukwenqaba ukuhamba.
Contraindication
Ukugoma akwenziwa uma kutholakele i-hypersensitivity to the drug or diphtheria toxoid.
Ukugoma akunqunyelwe uma kutholwa isifo esibuhlungu kakhulu sesifo esithathelwanayo noma olunye uhlobo. Ukugoma akwenzelwa ukuthi kubhebhethekise izifo ezingamahlalakhona: kulokhu, kufanele ulinde ukuthi kuxolelwe.
I-Contraindication icatshangelwa ukuthi ingafika emavikini angama-28 ubudala.
Indlela yokusebenzisa
Ezinganeni eminyakeni emibili yokuqala yokuphila, umuthi wokugoma unikezwa ekuhlonipheni ngaphambili kwethanga, uma umlenze uphuphuma, ukuvuselelwa kufanele kwenziwe esifundeni semisipha ye-gluteal. Izingane ezindala - esiswini esidonsayo sehlombe.
Ngaphambi kokujovwa, isikhumba sikhishwa ngogazi kukotini oswakanyiswe ngotshwala ukuze ulujove.
Musa ukuphatha umuthi wokugomela umuthi.
Imiphumela emibi
Ngokwazisa komijovo, ukuvuvuka kungakhula endaweni yomjovo. Kwezinye izimo, imiphumela emibi evela ezithweni nasezinhlelweni ezahlukahlukene iyabonakala.
Ezinganeni, i-hyperthermia iba njengokusabela okukhulu komzimba. Njengoba kusabela umuthi wokugomela, ubomvu nokuqina kobuhlungu kwenzeka endaweni yomjovo.
Amapheshana wesisu
Ukuqhaqha, isisu, ukuphambukela ekudleni. Ezimweni ezingavamile, i-jaundice ne-hepatitis esebenzayo kungenzeka.
Kusuka ohlelweni lokuphefumula
Ukukhwehlela, ukuqubuka kwamakhala.
Kusuka ohlelweni lomchamo
Ukuvuvukala kwesikhashana, ukugcinwa komchamo.
Izitho zeHematopoietic
Ama-lymph node akhulisiwe, ukukhula kwamaseli egazi amhlophe nama-lymphocyte ekuhlolweni kwegazi.
Isistimu yezinzwa ephakathi
Ukuxineka kobuhlungu, ukungaphatheki kahle, ukudabukisa. Ezimweni ezingavamile, kuye kwaba nezimo zokuqwasha, i-hyperacaction. Izingane ezingaphezulu kweminyaka emibili ubudala zingakhula ngokuziphatha okunolaka.
Allergies
Ukulunywa, okhalweni, i-edema engalunganga. Ukusabela okusheshayo komzimba okwenzeka ngokushesha ku-anaphylaxis kungenzeka.
Amahora angama-48 ngaphambi kokugoma kanye namahora angama-48 ngemuva kokuba kunganconywa ukuphuza iziphuzo eziqukethe utshwala.
Imiyalo ekhethekile
Bazali kudingeka balandele uhlelo lokugoma. Indawo yomjovo akufanele iphathwe nge-iodine, okuluhlaza okotshani, okokugcoba noma okumbozwe nge-band-aid.
Ungageza ingane, noma kunjalo, isayithi lomjovo alinakuthelwa futhi liphathwe ngendwangu yokuwasha. Ukuhlikihla ngethawula nakho akunconyiwe, ungamane umanzi kancane.
Ukuhambisana notshwala
Amahora angama-48 ngaphambi kokugoma kanye namahora angama-48 ngemuva kokuba kunganconywa ukuphuza iziphuzo eziqukethe utshwala.
Umthelela ekhonweni lokulawula izindlela
Akunconyelwe ukushayela imoto kungakapheli amahora angama-24 ngemuva kokugoma, ngoba kungavela ukukhula okujwayelekile komzimba nesiyezi.
Akunconyelwe ukushayela imoto kungakapheli amahora angama-24 ngemuva kokugoma.
Ukugonywa kwezingane
Izingane zinokushisa okuphezulu. Ezimweni ezingama-40%, izinga lokushisa lomzimba lenyuke laya ku-38 ° C, kwelinye lama-36% - ngaphezulu kwe-39 ° C. Ezinganeni esezikhulile, izinga lokushisa lenyuka kancane. Kungakapheli isigamu sehora ngemuva kokugoma, izingane kufanele zibe ngaphansi kokuqashwa ngudokotela, ngoba kungahambelana nokuhlangana kwezakhi zomuthi.
Ngesikhathi sokukhulelwa nokuqunjelwa
Umphumela wokugomela ingane noma ubisi lwebele awukasungulwa. Ukugoma akunconywa ngesikhathi sokukhulelwa. Uma kunesidingo sokugomela umama ongumhlengikazi, ingane idluliselwa kumsoco wokudla okwenziwe ngamathambo.
Ebudaleni
Ukugoma lapho usumdala ayenziwa, ngaphandle kwamacala okuthola ukugonywa okutholwayo. Ukugonywa kwabantu asebekhulile kwenziwa ezimweni lapho izifo ezihlasela njalo zamaphaphu zibhekwa khona noma kukhona ingozi ye-sepsis.
Ukweqisa
Amacala we-overdose awalungiswa, umuthi ulawulwa kuphela esimweni sesibhedlela futhi ngochwepheshe kuphela. Ngomthamo ongalungile, imiphumela emibi ehlelekile yaziwa kakhulu. Ayikho i-antidote ethile edingekayo.
Ukugoma lapho usumdala ayenziwa, ngaphandle kwamacala okuthola ukugonywa okutholwayo.
Ukuxhumana nezinye izidakamizwa
Akukho ukusebenzisana nezidakamizwa ezihleliwe ezitholakele.
Ngokunakekela
Kuvunyelwe ukuhlanganisa nomuthi wokugomela i-DTP. Bazali kumele balandele uhlelo lokugoma. Lapho wenza imigomo eminingana, udinga ukusebenzisa izingxenye ezahlukahlukene zomzimba ukuze ugweme ukuxuba izidakamizwa emzimbeni.
Inhlanganisela ayinconywa
Akunconyelwe ukwenza i-BCG ngasikhathi sinye nomgomo, ngoba kule ndaba umphumela uhlanekezelwa.
Ama-Analog
Ukufana komgomo wokugoma kukhona i-Premo 23 nePentaxim.
Imibandela yekhefu lekhemisi
Umuthi uthengiswa ngumbhalo kuphela.
Intengo ye-Prevar
Izindleko zomuthi zingama-ruble ayi-1900.
Izimo zokugcina zePrevenar yezidakamizwa
Gcina endaweni yokushisa ka- + 2 ... + 8 ° C endaweni emnyama, eyomile engenakufinyeleleka ezinganeni. Kwenqatshelwe ukumisa umuthi.
Isikhathi sokuphelelwa yisikhathi
Ilungele iminyaka emithathu kusukela ngosuku lokukhiqizwa.
Ukubuyekezwa mayelana nePrevenar
U-Ekaterina Radzinkevich, udokotela wezingane, eMoscow: "E-Russia, ukugoma i-pneumococcal akudingekile, kepha ukufakwa kwayo kuzovikela ngokumelene ne-bronchitis, pneumonia kanye nezinye izifo zokuphefumula. Kunconywa ukuthi kugonywe ehlobo, ngaphandle kwezikole kanye ne-kindergartens."
U-Oleg Beletsky, wezokwelapha, eNovosibirsk: "Umuthi wokugoma uvikela izingcezwana eziyi-13 eziphambili ze-pneumococcus, ngemuva kokugoma, ukuvikela igciwane elibangelwa amagciwane yi-93%."
Ukubuyekezwa kweziguli
ULarisa, oneminyaka engama-28 ubudala: "Le ngane yayigula kakhulu futhi ibucayi. Ngemuva kokugoma, kwaba nokushisa okuncane, ukubopha, ukulunywa endaweni yomjovo. Umphumela wabonwa ngenkathi ebandayo: bagula kancane."
U-Eugenia, oneminyaka engama-34: “Udokotela ungeluleke ukuthi ngiwuthole umjovo ngasikhathi sinye nomuthi wokugomela i-DTP. Ngemuva kokugoma, i-ARI iye yalimala, ingane izwa kahle.
