I-Diabeteson MV umuthi odluliselwa ngomlomo okuhloswe ngawo ukwehlisa ukugcwala kweglucose egazini.
Umuthi unezinto eziningi zokwelapha kanye nemiphumela emibi, edinga ukubambelela ngokuqinile emiyalweni yokusebenzisa amaphilisi.
Igama Lezwe elingafanele
IGliclazide (INN) igama lesithako esisebenzayo kumathebhulethi e-Diabeteson.
I-Diabeteson MV umuthi odluliselwa ngomlomo okuhloswe ngawo ukwehlisa ukugcwala kweglucose egazini.
I-ATX
I-A10BB09 - ikhodi yokuhlukaniswa kwamakhemikhali okwelashwa nokwelashwa.
Khipha amafomu nokwakheka
Umuthi usesimweni sethebhulethi sokusetshenziswa komlomo.
Ithebhulethi ngayinye iqukethe i-0.06 g yesithako esisebenzayo.
Umuthi uyatholakala emabhulashini ahlanganiswe emaphepheni amakhadibhodi. Ngayinye yayo iqukethe amaphilisi angama-30 noma angama-60.
Umuthi usefomini lethebhulethi ukuze usetshenziswe ngomlomo.
Isenzo se-Pharmacological
Into esebenzayo yesidakamizwa ivuselela ukukhiqizwa kwe-insulin ngamangqamuzana e-beta pancreas, esiza ukunciphisa ushukela wegazi.
Ngaphezu kwalokho, lapho uthatha umuthi, ubungozi bokulimala emithanjeni yegazi ngenxa yomthetho wezinzwa obuthakathaka buyancishiswa, ikakhulukazi uma kukhulunywa ngeziguli ezinesifo sikashukela sohlobo 2.
Umuthi uphathelene ne-sulfonylureas, sulfonamides.
I-Pharmacokinetics
I-Gliclazide icatshangelwa ngokuyinhloko esibindini. Imikhiqizo yokubola yesitho esisebenzayo ku-plasma ayibhekwa.
Ngemuva kokuphathwa ngomlomo, into esebenzayo igxila ngokuphelele emgodini wokugaya ukudla. Iqoqo eliphakeme kakhulu le-gliclazide ku-plasma yegazi libonakala ngemuva kwamahora ayi-6.
I-Gliclazide icatshangelwa ngokuyinhloko esibindini.
Ukudla akubathinti ubukhulu bokufakwa kwento esebenzayo.
Umuthi ukhishwa emzimbeni yizinso ezinomchamo.
Izinkomba zokusetshenziswa
Kunezici eziningi ezinjalo:
- Ithuluzi linconyelwa iziguli ezinobunzima obukhulu besifo sikashukela mellitus lapho ukulandela imigomo yokudla kokudla kungazange kube nemiphumela ephumelelayo yokwelapha.
- Umuthi uthathwa ukuvikela ukukhula kwezifo zesifo senhliziyo (isifo senhliziyo nemivimbo) kuhlobo 2 sikashukela.
- Umuthi awubekelwe abantu abanesifo sikashukela sohlobo 1.
Contraindication
Awukwazi ukusebenzisa ithuluzi emacaleni amaningi anjalo:
- Nge-ketoacidosis (ukwephulwa kwe-carbohydrate metabolism ngenxa yokuntuleka kwe-insulin).
- Uma isiguli singakafiki eminyakeni eyi-18.
- Nginenkinga yesifo sikashukela.
- Ngokushoda kwe-lactase.
- Uma kwenzeka ukungabekezelelani ngakunye kwengxenye esebenzayo.
Ngokunakekela
Akunconyelwe ukusebenzisa umuthi ezigulini lapho isifo sikashukela sikhula khona ngemuva kwesizinda sokudakwa okungapheli, kanye nabantu abanenkinga yesibindi eqinile ukuze bagweme imiphumela emibi.
Ungasithatha kanjani isifo sikashukela?
Udokotela kuphela onquma umthamo ngqo wento esebenzayo, kucatshangelwa izici zomzimba ngamunye.
Imiyalo yokusebenzisa umuthi i-Trulicity.
Amathebulethi e-Amaryl athathwa ngesikhathi sokushintsha kweglucose yegazi.
Yiziphi izinzuzo zozaqathi zesifo sikashukela? Funda ngakho esihlokweni.
Ngaphambi noma ngemuva kokudla?
Ukusebenza kwethonya lokwelapha alithinteki ukuthola ukudla. Kepha kubalulekile ukuphuza iphilisi elinamanzi amaningi.
Ukwelashwa nokuvimbela isifo sikashukela
Ukuthola amandla amahle ezimpawu zomtholampilo, kunconywa ukuqala ukuthatha umuthi nge-30 mg ye-gliclazide kanye ngosuku. Ngemuva kwalokho umthamo wanda kancane kancane uye ku-60-120 mg ngosuku.
Ukusebenza kwethonya lokwelapha alithinteki ukuthola ukudla.
Ekwakheni umzimba
Amacwecwe anconywe ukuba athathwe kathathu ngosuku. Umuthi unomphumela omuhle ekuguqulweni kwamafutha omzimba abe izicubu, esiza ukusheshisa ukukhula kwemisipha. Ngaphezu kwalokho, umkhiqizo uvikela umzimba emiphumeleni elimazayo yezinto ezinobuthi.
Ukwehla kwesisindo
Ithuluzi lisetshenziselwa ukugcina i-anabolism ephezulu, ngakho-ke awukwazi ukusebenzisa umuthi ukuze wehlise isisindo, ngoba lokhu akugcini nje ekuholeni umphumela omuhle, kepha futhi kukhombisa imiphumela emibi eminingi.
Imiphumela emibi
Umuthi ubangela ukusabela okuningi okungathandeki komzimba, ngakho-ke kubalulekile ukubonana nodokotela wakho kuqala. Ukuzilolonga kungaholela ekwakhiweni kwezinkinga.
Umuthi ubangela ukusabela okuningi okungathandeki komzimba, ngakho-ke kubalulekile ukubonana nodokotela wakho kuqala.
Amapheshana wesisu
Imvamisa kuba khona izinhlungu esiswini nokuhlanza. Kepha ukubukeka kwalezi zimpawu kungagwenywa uma uthatha umuthi ngesikhathi sokudla kwasekuseni.
Izitho zeHematopoietic
I-hememotic anemia ayiveli ukukhula.
Isistimu yezinzwa ephakathi
Ezimweni ezingavamile, ukuthuthukiswa kokudangala kuyabonakala. Ukuphazanyiswa ukwazi nokulahlekelwa ukuzithiba kuyimpawu.
Ezimweni ezingavamile, ukuthuthukiswa kokudangala kuyabonakala.
Kusuka ohlelweni lomchamo
Akuvamile ukubonwa kokuchama okuvamisile.
Engxenyeni yezitho zombono
Umsebenzi wokubona uyakhula ngokusetshenziswa isikhathi eside kwesidakamizwa.
Engxenyeni yesikhumba
Ngokuphikisana nesizinda sokungabekezeleleki kwengxenye ethile esebenzayo, kwenzeka ukuqhuma, okuhambisana nokulunywa nokubomvu kwesikhumba.
Engxenyeni yesibindi ne-biliary
Iziguli zinomsebenzi owandayo wama-enzyme wesibindi. IHepatitis ayiveli.
Umsebenzi wokubona uyakhula ngokusetshenziswa isikhathi eside kwesidakamizwa.
Imiyalo ekhethekile
Kubalulekile ukulandela imithetho yokuthatha i-Diabeteson.
Ukuhambisana notshwala
Ungaphuzi iziphuzo eziqukethe utshwala ngenkathi ulashwa nomuthi, ngoba Ukuziphatha okunjalo kuholela ekwehleni kwempumelelo yokwelashwa komuthi.
Umthelela ekhonweni lokulawula izindlela
Umuthi uvunyelwe ukusetshenziswa ngabantu abamisebenzi yabo ehambisana nokunakwa okukhulu.
Kodwa kubalulekile ukuthi iziguli zikhumbule mayelana ne-glypoglycemia enokwenzeka, ehambisana nokudideka nokuxhumana okungahambi kahle kokunyakaza.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Kufanele uyeke ukuphuza umuthi ngesikhathi sokukhulelwa ngenkathi uncelisa ibele, ngoba kunobungozi obukhulu bemiphumela emibi yengxenye esebenzayo emzimbeni wengane.
Kuyadingeka ukuyeka ukuphuza umuthi ngesikhathi sokukhulelwa ngenkathi uncelisa ibele.
Udokotela ukhetha ezinye izinketho zemithi yomlomo ye-hypoglycemic.
Ukunquma uDiabeteson ezinganeni
Ukuthatha umuthi ezinganeni kuvinjelwe.
Sebenzisa ebudaleni
Ukulungiswa kwedose kweziguli ezingaphezulu kweminyaka engama-60 akudingekile.
Isicelo sokusebenza kokulimala kwezinso
Asikho isidingo sokulungisa umthamo wento esebenzayo ezigulini ezihluleka ngokwezinso.
Sebenzisa umsebenzi wesibindi okhubazekile
Ukubonisana nodokotela kuyadingeka ngaphambi kokuqala ukusebenzisa umuthi.
Asikho isidingo sokulungisa umthamo wento esebenzayo ezigulini ezihluleka ngokwezinso.
Ukweqisa
Uma kwenzeka kweqisa umthamo obekwe udokotela, kuyehla ukwehla okukhulu ushukela wegazi. Ukulawulwa kwe-glycemic kuyadingeka.
Ukuxhumana nezinye izidakamizwa
Kunezidakamizwa ezimbalwa ezingenakusetshenziswa ngasikhathi sinye nesifo sikashukela.
Inhlanganisela ehlanganisiwe
Endabeni yokusebenzisa iMiconazole ngesimo sejeli ukuphatha i-mucosa yomlomo noma ngokuphathwa ngokuhlelekile komuthi, kunengozi enkulu yokuba ne-glypoglycemia ibe ukoma.
Kunezidakamizwa ezimbalwa ezingenakusetshenziswa ngasikhathi sinye nesifo sikashukela.
Akuhlanganisiwe ukuhlanganisa
I-Phenylbutazone neDanazole, uma ithathwa ndawonye neDiabeteson, ithuthukisa umphumela we-hypoglycemic.
Ukuphuza utshwala futhi kukhuthaza ukukhula kwe-glypoglycemia. Kubalulekile ukuyeka ukusetshenziswa kwemikhiqizo equkethe i-ethanol.
Inhlanganisela edinga ukuqashelwa
Kuhlanganiswe ne-Metformin, i-Acarbose, i-Insulin, ukwanda komphumela we-Diabeteson kuyabonakala.
Isifo sikashukela
IManinil iyisikhundla esisebenzayo somuthi, kepha lesi sidakamizwa sibangela eminye imiphumela emibi.
I-Diabeteson (igama lesi sidakamizwa ngesiLatini) ingathengwa ekhemisi ngomuthi kadokotela.
ISiofor, iGlibomet ne-Amaril ziyizichazi ezibizayo zeDiabetes.
Imibandela yekhefu lekhemisi
I-Diabeteson (igama lesi sidakamizwa ngesiLatini) ingathengwa ekhemisi ngomuthi kadokotela.
Ngingakwazi ukuthenga ngaphandle kadokotela?
Umuthi umuthi obhalwe phansi. Ukuzelapha ngokwakho akunconywa; bonana nodokotela.
Intengo Yesifo Sikashukela
Izindleko zomuthi zingama-ruble angama-350.
Izindleko zomuthi zingama-ruble angama-350.
Izimo zokugcina zomuthi
Kubalulekile ukugcina umkhiqizo endaweni evikelwe ukukhanya kwelanga.
Isikhathi sokuphelelwa yisikhathi
Izici zokwelapha zomuthi zigcinwa iminyaka engu-2 kusukela ngosuku lokukhiqizwa.
Umkhiqizi
Umakhi waseRussia yiSerdix LLC.
Ukubuyekezwa kwesifo sikashukela
Kunemibono emihle futhi engemihle ngalesi sidakamizwa esivela kubo bobabili odokotela neziguli.
Odokotela
U-Alexey, eMoscow, iminyaka engu-35.
Wanelisekile ngomphumela wokwelapha iziguli ezinesifo sikashukela. Ukukhetha okulungile komthamo wento esebenzayo kubalulekile, kanye nokugcinwa kwemigomo yokudla ngesikhathi sokuphathwa kwe-capsule. Ebhekene namacala wokuthuthukiswa kwe-hypoglycemia ngokwephula umthamo osungulwe ngudokotela. Ukuqhuma okukhulu kwemikhawulo ephezulu kwabonwa ezigulini, kwasungulwa i-hyperhidrosis (izithukuthuku ezibandayo nezingcolile), kwavela i-tachychardia.
UMikhail, oneminyaka engama-43 ubudala, eSt Pererburg.
Ngikholwa ukuthi ukuze kugwenywe izinkinga, kubalulekile ukunikeza umuthi ngokuqapha kanyekanye nezidakamizwa ezinciphisa umfutho wegazi.
Isifo sikashukela
U-Ana, oneminyaka engama-32 ubudala, uPret.
Sekuyisikhathi eside ngisebenzisa lo muthi. Akunamiphumela emibi yenzekile. Ngithanda ukuthi leli thuluzi lisuse isidingo sokwenza imijovo yansuku zonke.
U-Olga, oneminyaka engama-41, u-Omsk.
Ubhekene nesiyezi nokuhlanza ngemuva kokuthatha umuthi. Udokotela uveze ukungabekezeleli kwe-organic kulokho okusebenzayo. Kepha intombi ijabule ngemiphumela yokwelashwa. Kubalulekile ukubonana nodokotela ngesikhathi esifanele uma kwenzeka kuvela imiphumela emibi.
U-Oleg, oneminyaka engama-24 ubudala, u-Ufa.
Angithandi iqiniso lokuthi ukulawulwa glycemic okuqhubekayo kuyadingeka ekuthatheni isifo sikashukela, ngoba lesi yisimo esibalulekile sokwehluleka kwesibindi. Kepha kufanelana neqiniso lokuthi ngithatha amaphilisi kanye ngosuku. Ngiyabonga ukuthi kulula nokusebenziseka kalula komkhiqizo.
