Ukuxilongwa kwe-pancreatic atrophy kusho ukuthi umthamo wesitho sangaphakathi sehlile, okukhonjiswa yi-exocrine (digestive enzymes) kanye ne-intracecretory (ukukhiqizwa kwe-insulin ne-glucagon) ukungasebenzi kahle kokusebenza.
Kwimidwebo eminingi, i-pathogeneis kungenxa yohlobo lwe-pancreatitis olungapheli, isifo sikashukela, i-somatic pathologies ngokukhathala okukhulu, i-cirrhosis, nokuphazamiseka kokujikeleza kwegazi. Kwesinye isikhathi imbangela yilesi isimila.
Ukwenza ukuxilongwa okunembile, kutholakala ukuxilongwa okuhlukile. Naka imiphumela yelaborathri ekhombisa ukuntuleka kwama-enzymes wokugaya kanye nenqwaba ye-insulin.
Ukuhlolwa kwe-ultrasound kuyenziwa impela, okufakazela ukwehla kwezindlala, ushintsho lwe-pathological ku-parenchyma. Ukwelapha kuqukethe ukuqokwa kokulashwa okulandelayo. Bancoma umuthi we-enzyme, i-insulin, amaphilisi wokubuyisa i-microflora yamathumbu.
I-pathogenesis yezinguquko ze-atrophic kumanyikwe
Izinguquko ze-atrophic kumanyikwe ziba ngokomzimba lapho zikhula ngenxa yenqubo yemvelo yokuguga. Zihambisana nezifo ezibuthakathaka kakhulu.
Ngaphezu kwalokho, i-atrophy ingumphumela wanoma yiluphi uhlobo lwe-pancreatitis engapheli, nengxenye ebalulekile ye-stroma 
Ifakwa izicubu ze-fibrous, okuholela ekwandeni okubukhali kokungapheleli kwe-endocrine kanye ne-exocrine.
Imvamisa, isisindo sesitho sangaphakathi siyahlukahluka kusuka kuma-80 kuye kuma-90 g. Uma izinguquko ezingejwayelekile zibonwa kuso, khona-ke sehla saya ku-30-40 g nangaphansi. Kukhona ushintsho ekwakhekeni kwesitho uqobo. Ukulimala kwezicubu ezixhunywayo kuwuphawu lwalesi sifo.
I-pancreatic atrophy yenzeka ngalezi zizathu ezilandelayo:
- Ukuvela kokuwohloka kwamafutha esitho.
- Izinkinga zesifo sikashukela.
- Ukuhlukumeza utshwala, ukubhema.
- Isilonda se-duodenal, isisu.
- Ukudla okungenampilo.
- I-Autoimmune pathologies ethinta i-patity esiswini.
- Ukuphinda usebenzise i-RV.
I-Atrophic pancreatitis ngokumelene nesifo sikashukela i-mellitus ithatha indawo ekhethekile. Lesi sifo sibonisa ngokuncipha okukhulu kwesitho size sifinyelele ku-20 g, ukuqina kwako kuba denser, ingaphezulu libanda kakhulu, i-capsule ihlangana nezicubu ezinamafutha nezitho eziseduze.
I-Lipomatosis ibuye ivele njengefomu le-atrophic lesifo se-pancreatic. Yize lesi sifo sibonwa ngosayizi ojwayelekile wesitho noma ukwanda kwaso, kepha iningi laso lithathelwa indawo izicubu ze-adipose, lapho kulandelwa izingxenye ezithile zaso zeglandular. Ezimweni ezingama-80% ezinesifo esinjalo, i-islet apparatus nomsebenzi we-endocrine ziyagcinwa.
Iqembu lengozi lifaka iziguli ezinesifo sofuzo, ukuxhomekeka kotshwala, ukulimala esiswini, izifo ezithathelwanayo zezitho zangaphakathi, i-cholecystitis ebalwayo.
Ukubonakaliswa kwezempilo kwe-atrophy
Lapho sesihlolile ukutholakala kwe-pancreatic atrophy, ukuthi kuyini, nokuthi isitho singasidonsa kanjani, sizothola ukuthi yiziphi izimpawu ezibonisa ukwelashwa kwegazi. Izimpawu zidalwa yi-etiology yokuthuthuka kwenqubo ye-pathological emzimbeni (ukuthikameza i-glucose up, i-pancreatitis engapheli, njll.).
Kungakhathaleki ukuthi ziyini imbangela nezizathu ezidabukisayo, kuzo zonke iziguli kunokusilela kwemvelo ye-endocrine kanye nemvelo engaphandle. Ukuntuleka kwemfihlo yangaphandle kuhambisana nokuncipha kokukhiqizwa kwama-enzymes wokugaya, ama-electrolyte, asiza ukuguqula okuqukethwe kwesisu, kusiza ukuhlinzeka ngendawo evamile yama-enzyme e-pancreatic.
Iziguli zikhononda ngokwephulwa komgudu wokugaya ukudla, ovame ukubonakaliswa:
- Isifo sohudo.
- Yehlise iphango.
- Ukwehla kwesisindo.
Isibonakaliso sokuqala sokwehluleka kwe-exocrine ukwanda kwe-fat kanye nezindunduma. Lesi sibonakaliso sitholwa ngemuva kwesizinda sokwehla komkhiqizo ngamaphesenti ayi-10 yenani elijwayelekile.
Isiguli siqala ukunciphisa umzimba ngokushesha. Lokhu kungenxa yokuthi inqubo yokugaya ukudla, ethola izakhamzimba ezisegazini esiswini iyaphazamiseka, iphango liyancipha. Uma umuntu ene-atrophic pancreatitis engapheli, khona-ke ukuhlolwa kwelabhoratri kukhombisa ukuntuleka okukhulu kwamavithamini namaminerali.
Ukungapheleli kwe-Endocrine kutholwa yi-carbohydrate metabolism disorder eyenzeka njenge-hyperglycemic syndrome.
Kodwa-ke, yingxenye kuphela yeziguli ekhononda ngayo izimpawu zesifo sikashukela (ukuchama okusheshayo, umlomo owomile, ukusetshenziswa njalo kwendlu yangasese, njll.).
Ukuxilongwa okuhlukile
Lapho uhlola isiguli ku-90% yezithombe zomtholampilo, kutholakala isisindo sokusilela kwesisindo. Isikhumba siba mncanyana, somile ngokweqile. Imvamisa kunezinto ezingenakuphikwa. Kulokhu, i-palpation ayikuvumeli ukuthi "uzizwe" ukuncipha kwesitho sangaphakathi.
Lapho i-pathogenesis isuselwe ekutholakaleni kwe-pancreatitis, lapho-ke palpation isiguli sikhononda ngemizwa ebuhlungu noma ukungaphatheki kahle. Imiphumela yokuhlolwa kwegazi okune-biochemical ikhombisa ukuthi umsebenzi wama-enzymes wokugaya wehlile.
I-programme isiza ukubona amafutha emafutheni (i-steatorrhea). Njengomthetho, ngaphezu kwe-10% yokusetshenziswa kwansuku zonke kutholakala kumalongwe. Inani lemicu yemisipha esesitobhini landa kakhulu, okuwukuphambuka kokujwayelekile.
Ezimweni eziningi, ucwaningo ngokubandakanyeka kwe-glucose libonisa ukwanda okukhulu, okudinga ukuvakasha okwengeziwe kodokotela abanjengo-endocrinologist noma isifo sikashukela.
Ezinye izindlela zokuthola lesi sifo:
- Ukwenza ukuhlolwa kwe-pancreas ye-ultrasound kukhombisa ukwehla kwe-pathological esitho sangaphakathi. Isakhiwo siba minyene, i-echogenicity iyanda, ukwakhiwa okulinganayo akulingani.
- I-MRI iyanconywa ezimweni lapho i-ultrasound inganikanga imininingwane ephelele futhi imininingwane eyengeziwe iyadingeka ukuthola amaqhinga aphathelene nokwelashwa.
- I-RCP ibekelwe ukuthi ihlole isimo semidumba, ukuthola izinguquko ezivame ukuhambisana nokuqina kwesikhumba. Ngenxa yokukhohlisa okunjalo kwezokwelapha, kungenzeka ukuthi kutholakale ukwehla kwezicubu ze-pancreatic, ukuhlukunyezwa kanye nokungalingani kwezindonga.
- I-Angiography iyadingeka ezimweni lapho uchwepheshe wezokwelapha esola inqubo yesimila. Inqubo ikuvumela ukuthi uphike noma uqinisekise ukucabanga.
I-biopsy ye-pancreas iyimpoqo. Ocwaningweni lwelabhoreji lwesampula ethathiwe, kuhlolwa isilinganiso se-fibrosis kanye nokubhujiswa kwe-parenchyma, isimo sezinto zezindlala nezindawo ezikhiqiza i-insulin.
Le ndlela yokuxilonga ikuvumela ukuthi uveze ukuvelela kwalesi sifo.
Imithi yokwelashwa kwe-pancreatic atrophy
Esibonelweni sokuqala sezinguquko ze-atrophic kuma-pancreas, kunconywa kuqala ukudla. Isiguli kudingeka sinciphise ukungena kokudla okuqukethe amafutha ezilwane.
Kuyadingeka ukunaka ukuntuleka kwezinto ezinamaprotheni emzimbeni, ukushoda kwamandla, nokulungisa ukuntuleka kwamavithamini namaminerali. Njengoba i-nicotine inomthelela ekuphazamisweni ekukhiqizweni kwama-bicarbonates esitho sangaphakathi, ugwayi kufanele ulahlwe.
Ukuma okuyinhloko kokwelashwa okuquketheni kuqukethe ukwelashwa okubuyiselwe esikhundleni somsebenzi we-exocrine and secracecretory secretion. Kunconywa izidakamizwa ze-Enzymatic ukunxephezela lezi zinqubo.
Ukuze uthole umphumela owuthandayo wokwelapha, imithi kufanele iboniswe ngezinga eliphakeme lomsebenzi we-lipase, akufanele ichithwe ngaphansi kwethonya lejusi lesisu. Kulokhu, amaphilisi adinga ukufaka isandla ekwenziweni kokukhishwa okusheshayo kwezinto ezingama-enzyme emathunjini amancane, ukukhuthaza inqubo yokugaya.
Ama-Microbeads ahambisana nazo zonke izidingo ezichaziwe. Njengoba kuyi-lipase elahlekelwa umsebenzi ngokushesha, ngakho-ke, ukulungiswa kwenziwa ngokucabanga kokuqukethwe kwayo emithini kanye namandla e-steatorrhea (okuqukethwe kwamafutha emgodini).
Ukusebenza kokulashwa okunconyelwe kunqunywa: izinga lokunciphisa i-steatorrhea kanye ne-elastase in feces. Ukulungiselela i-enzyme kusiza ukufeza umphumela olandelayo wokwelapha:
- Yehlisa ukungena kwesibili.
- Jwayela i-microflora emathunjini.
- Bafaka isandla ekuthuthukiseni i-carbohydrate metabolism.
Ukuze unciphise usizi lobuhlungu, nikeza imishanguzo ehlobene nama-analgesics nama-antispasmodics. Umthamo unqunywa ngawodwana, ngokuya ngobukhulu besifo sezinhlungu. Kunconywa imijovo yePapaverine, i-No-shpu, i-Analgin nezinye izidakamizwa.
Ukulungisa ukungapheleli kwe-endocrine, ukwethulwa kwe-insulin kuyadingeka. Ngezinguquko ze-atrophic, ukufa kwe-islet cell akubonwa, ngakho-ke, kukhiqizwa i-hormone, kepha ekuhlushwa okuphansi. Umthamo kanye nokuvama kokusetshenziswa kwe-insulin ukwelashwa kuncike enkambweni yesifo, i-etiology yesifo, imiphumela yocwaningo lwansuku zonke lweglucose emzimbeni.
Isimo esibalulekile ukulungiswa kwemisebenzi yokugaya ukudla, ikakhulukazi, ukwenziwa okujwayelekile kwe-microflora yamathumbu. Ngakho-ke, ama-probiotic nama-prebiotic asetshenziswa.
Ngaphezu kwalokho, kunconywa amalungiselelo aqukethe amavithamini. Kuyadingeka futhi ukugcwalisa ukusilela kwalezi zinto ezilandelayo zamaminerali:
- Magnesium
- I-Zinc
- Copper.
Izithasiselo ezisebenzayo ngokwendalo zingabekwa ngesimo sezidakamizwa eziningana, noma isidakamizwa esisodwa, esifaka kanyekanye izinto ezidingekayo ekwakhekeni kwaso.
Ukungenelela kokuhlinzwa kwenziwa emitholampilo ekhethekile. Inqubo ifaka ukufakelwa kweziqhingi zaseLangerhans ngokubuye kwenziwe kolwelwesi okwenziwe ngokulandelana kwamanyikwe kanye nokufakwa esikhundleni kwe-enzyme.
Njengoba izinguquko ze-atrophic kuma-pancreas zingumphumela we-pathologies enobunzima obukhulu bokuphazamiseka kwesimo esijwayelekile sesiguli, ukwelashwa okuhlinzwa akuvamile ukunqunywa.
Isimo sezulu nokuvikela
Ukucatshangelwa komphumela walesi sifo kususelwa ebangeni lokulimala kwemisebenzi ye-exocrine kanye ne-intracecretory. Njengoba amaseli we-islet agcinwe ngokwengxenye, ngokufanele, kukhona ukukhiqizwa okusele kwe-insulin. Ngakho-ke, isimo se-ketoacidotic asitholakali kakhulu ukuthi sitholakala, kepha ukwehla kakhulu ushukela wegazi kuvame ukuvela.
Ukunquma i-pathogenesis yenqubo ye-pathological, kuqeda "umthombo" - isifo esiyinhloko, ukuqalwa kwezokwelapha okufika ngesikhathi - wonke lawa maphuzu akuvumela ukuthi uzuze imiphumela emihle yokwelashwa kanye nokuqashelwa okuhle.
Njenge-prophylaxis, ukubuyekezwa kweziguli kuncoma ukusebenzisa izindlela zemithi yendabuko. Basiza ukuthuthukisa ukusebenza kwamanyikwe, basize ukuthuthukisa ukugaya, kanye nokuvikela ukuphazamiseka okukhulu emzimbeni.
Ukwelapha, kusetshenziswa izitshalo zokwelapha - i-hawthorn, i-dill, i-peppermint, i-pharmacy chamomile, njll. Le iresiphi elandelayo isiza ukuxhasa umzimba: hlanganisa izipuni ezintathu zembewu dill nenani elifanayo le-mint, engeza izipuni ezi-2 ze-hawthorn, isipuni esisodwa se-chamomile ye-pharmacy. Thela amanzi abilayo. Hlunga. Thatha i-100 ml kane ngosuku. Inkambo yokwelashwa ingamaviki amabili.
Njengokuvimbela, kunconywa ukulandela izincomo:
- Ukuyeka ukubhema, utshwala.
- Ukwelashwa okufika ngesikhathi kwezifo ezingamahlalakhona.
- Ukudla okulinganiselayo nokunempilo.
- Ukugcina izinga elidingekayo lomsebenzi we-enzyme.
- Ukulonda impilo esebenzayo. Ukuzivocavoca okulinganiselayo nge-pancreatitis, ikakhulukazi i-yoga nokuhamba, kuzoba wusizo olukhulu.
I-Atrophy ye-pancreas yisifo esibi, Ngakho-ke, lapho kuvela imizwa ebuhlungu esifundeni se-epigastric, kufanele kuvakashelwe isikhungo sezokwelapha. Ukwelashwa okusheshayo kuqalile, yilapho ukuthandela ukwedlula okukuhle kakhulu.
Imisebenzi kanye ne-pathologies ye-pancreas kuchazwe kuvidiyo kule ngxenye.
