Ungasisebenzisa kanjani isidakamizwa iVazonit?

I-Vazonit yezidakamizwa ingeyeqembu lama-angioprotective agents. Kuthuthukisa ukuhanjiswa kwegazi kwizitho zezitho, kuvumelana nokwakheka kwemithambo yegazi. Umphumela omuhle uyaphawuleka ngenxa yokubuyiselwa kokuqalwa kwegazi. Lesi sidakamizwa sinikezwa ngefomu elilodwa lomthamo. Ihlukaniswa yizinga elanele lokusebenza ngempumelelo ekwelashweni kwezifo ezibangelwa ukuphakelwa kwegazi okungalungisiwe ezithweni nasezithanjeni zezingxenye ezahlukahlukene zesistimu yokujikeleza kwegazi.

I-ATX

C04AD03 Pentoxifylline.

Khipha amafomu nokwakheka

Umuthi usesimweni samacwecwe. I-Pentoxifylline isetshenziswa njengezakhi ezisebenzayo. Umthamo wayo kuthebhulethi eyi-1 600 mg. Ithuluzi liqukethe izinto ezengeziwe, kufaka phakathi:

• i-hypromellose;
• i-microcrystalline cellulose;
• i-crospovidone;
• i-silicon dioxide colloidal;
• i-magnesium stearate.

I-Vazonit yezidakamizwa ingeyeqembu lama-angioprotective agents.

Isenzo se-Pharmacological

Izici zesidakamizwa okukhulunywa ngaso: i-angioprotective, i-antiplatelet. Ngaphezu kwalokho, umuthi unomthelela ekwandeni kwemithambo yegazi. Ngesikhathi sokwelashwa, kuqapheleka ushintsho ekwakhekeni kwegazi, okuholela ekwandeni kwegazi laso. Ngokwengxenye, lo mphumela unikezwa ngenxa yomphumela wokukhubazeka kwamangqamuzana abomvu egazi, aguqulwe ngenxa yokwakhiwa kwe-pathology.

Ukuqina kwe-membrane ye-erythrocyte kuyanda. Umuthi uvimbela inqubo yenhlangano yabo nama-platelet. Ngenxa yalokhu, izinga lokubonakala kwegazi laziwa ngokujwayelekile. Lokhu kusizwa ukwehla kwamazinga e-fibrinogen, kusebenze inqubo yokubhujiswa kweziqalo zegazi. Ezindaweni lapho ukulethwa kwegazi kwezicubu nezitho zomzimba kwakulinyazwa khona, ukushesha lapho kuqhutshwa umoya-mpilo nokulethwa kwezakhi kwaphawulwa. Lokhu kungenxa yokuvuselelwa kwe-microcirculation. Umuthi uthoba kancane imithambo ye-coronary.

Ngaphezu kwalokho, umuthi unomthelela ekwandeni kwemithambo yegazi.

Umphumela omuhle emzimbeni kungenxa yokuthi i-ejenti okukhulunywa ngayo itholakala kuma-xanthines. Lezi zingxube ze-purine ye-purestoline encibilikayo etholakala kwezicubu noma kuphi.

I-Pharmacokinetics

Ukusatshalaliswa okufanayo kwe-metabolites yento esebenzayo emzimbeni wonke kuyaphawulwa. Ukufakwa egazini kuvela emgodini wokugaya ukudla. Umsebenzi ophakeme wesidakamizwa awutholakali ngaphambi kwamahora ama-3-4 ngemuva kokuthatha i-capsule. Ukuguqulwa kwesakhiwo esisebenzayo kwenzeka esibindini. Umphumela owelapha okwenziwa kuwo awuhlali isikhathi esingaphezu kwamahora ayi-12.

Umuthi uyadedelwa ngenkathi uchama. Kulokhu, ikakhulukazi ama-metabolites aphuma emzimbeni.

Yini ebekiwe?

Umuthi okukhulunywa ngawo uvame ukusetshenziselwa izifo zemvelaphi yemithambo, kufaka phakathi:

• ukuphazamiseka okuhlukahlukene kokujikeleza kwemithambo ye-peripheral, lokhu kufaka izimo zokugula: i-atherosulinosis obliterans (isiyezi, ikhanda, ukunakwa okungahambi kahle), ukugcizelela okwenzeka ngezikhathi ezithile nge-microcirculation emaphethelweni, isifo sikaRaynaud;
• i-angioneuropathy, i-encephalopathy yezinhlobo ezahlukahlukene;
• ukuhlaselwa i-ischemic, ukululama ngemuva kokushaywa unhlangothi;
• i-neuroinfection yegciwane;
• ushintsho ekwakhekeni kwezicubu zemvelo ye-trophic, okungahle kudalwe ukwephulwa kwe-arterial or venous microcirculation, lokhu kwanda kwenzeka ngezifo ezifana nokulimala kwe-venous, ukwephulwa kwesakhiwo sesikhumba ngesikhathi sokusha, i-frostbite, ulcerative vidions of a trophic nature, exacerbation of thrombophlebitis;
• ukukhubazeka kwezindlebe ngenxa yokuphazamiseka kokujikeleza emithanjeni yendlebe ephakathi;
• ukulahleka kombono ekwakhekeni kwezifo zamehlo, kufaka phakathi izimo zengqondo ezibangelwa ukulimala kwemishini kokwenza iso, kufaka phakathi nokuphazamiseka kokujikeleza kwegazi okungapheli e-retina;
• ukungasebenzi kwezitho zangasese zabantu, okucasulwe ukulimala kwemithambo;
• umlando wesifo somoya (brunchial asthma);
• ukunakekelwa kokuntuleka kokuphazamiseka ekuhlaselweni kwe-ischemic.

Umuthi okukhulunywa ngawo uvame ukusetshenziselwa ukuphazamiseka okuhlukahlukene kokujikeleza kwemithambo yegazi.

Umuthi okukhulunywa ngawo uvame ukusetshenziselwa unhlangothi we-ischemic.

Umuthi okukhulunywa ngawo uvame ukusetshenziselwa i-asthma ye-bronchial.

Contraindication

Izinkomba eziphambili zokulinganiselwa kuyizindlela ezinamandla zezifo zemvelaphi yemithambo yegazi. Lokhu kufaka phakathi:

• ukusabela okungekuhle komuntu ngamunye kufomu elisebenzayo ekwakhekeni kwalo muthi, nakwezinye izinto ezitholwayo ze-xanthine;
• ukopha, ikakhulukazi okusindayo;
• infarction myocardial esigabeni esibuhlungu;
• ukushaya kwe-hemorrhagic;
• i-porphyria;
• ukuphuma kwezitho zomzimba ezithweni zombono;
• iminyaka yeziguli ezingaphansi kweminyaka engu-18 ubudala, ngenxa yokushoda kolwazi ngomphumela walesi sidakamizwa emzimbeni wezingane.

Contraindication ifaka ukusabela okungekuhle kwesimo umuntu ngamunye.

Contraindication ifaka i-myocardial infarction esigabeni esibuhlungu.

Contraindication ifaka i-hemorrhage ezithweni zombono.

Ngokunakekela

Ngaphezu kokuphikisana ngokuphelele okuxoxwe ngakho ngenhla, kunemikhawulo eminingi engahle yephulwe uma kunesimo esiphuthumayo. Phakathi kwazo kukhona:

• ubungako bomzimba wesiguli ku-hypotension;
• ukulimala kwemithambo yobuchopho yemvelaphi ye-atherosulinotic;
• ukukhula kwenhliziyo;
• izilonda zokulimala kolwelwesi lwama-mucous wesistimu yokugaya ukudla (ikakhulukazi isisu ne-duodenum);
• ukwehluleka okungapheli kwezinso, ukungasebenzi kwesibindi;
• imisebenzi yamuva.

Ngokuqapha, kufanele uthathe umuthi wokuthuthukisa ukuhluleka kwenhliziyo.

Ngokuqapha, kufanele uthathe umuthi ukuze uthole izilonda zokulimala kolwelwesi lwama-mucous lohlelo lokugaya ukudla.

Ukuqapha kufanele kuthathwe lapho isiguli sithambekele ekuqothulweni kwe-hypotension.

Ungayithatha kanjani i-vasonite?

Ukwehlisa izinga lokufutheka, umuthi kufanele udakwe ngaphandle kokuhlafuna. Izibhebhe ziyagezwa ngamanzi. Isikhathi sesifundo sinqunywa ngawodwana. Ezimweni eziningi, amaphilisi anconyiwe ukuba aphathwe isikhathi esishiyana kusuka kumaviki amabili kuya ezinyangeni eziningana.

Ngaphambi noma ngemuva kokudla?

Kunconywa ukuphuza umuthi ngemuva kokudla.

Kwabadala

Imiyalo esetshenzisiwe:

1. Umthamo wansuku zonke wekhompiyutha esebenzayo ngu-1200 mg.
2. Lelinani lezidakamizwa kumele lihlukaniswe ngemithamo engu-2-3.
3. Ngemuva kokuthi izimpawu zesifo zincishisiwe, umthamo wehliswa ube ngu-300 mg (inani lansuku zonke). Lesi sincomo sisebenza kakhulu kwiziguli ezinesifo sesibindi.

Umthamo wansuku zonke wekhompiyutha esebenzayo ngu-1200 mg.

Iziguli ezinenkinga yokwehluleka kwezinso zibekelwa inani elincane lomuthi - 600 mg ngosuku. Uma kunesidingo, lomthamo ubuye uhlukaniswe ngemithamo engu-2-3. Ngokwesilinganiso esincane se-pentoxifylline, inkambo yokwelashwa kufanele iqale futhi ezimweni lapho isiguli sithambekele ekwehliseni umfutho wegazi.

Okwezingane

Umuthi awunqunyelwe.

Ngoshukela

Ukusetshenziswa komthamo omkhulu kungadala i-hypoglycemia. Ukugwema imiphumela enjalo, kudingeka ukulandisa kwenani le-pentoxifylline. Umthamo oqondile weziguli ezinesifo sikashukela unqunywa ngawodwa.

Imiphumela emibi

Uma unikezwe ukuthi umuthi ubandakanyeka ezinqubweni ze-biochemical, kuvame ukusabela okungekuhle entweni esebenzayo. Ukwanda kokubonakaliswa kwawo kuya ngohlobo lwesifo kanye nesimo somzimba ngesikhathi izimpawu zenzeka. Iqembu lokulimala okujwayelekile lifaka ukonakala kombono we-peripheral, ukuvuvukala kolwelwesi lwama-mucous ama-sinuses, ukuqina kwezipikili, ubuthakathaka emzimbeni kanye nobuhlungu endlebeni.

Iqembu lokulimala okujwayelekile lifaka ukonakala kombono we-peripheral.

Amapheshana wesisu

Kukhona ithuba lokwehla kwesifiso sokudla, esivame ukwenzeka ngemuva kwesizinda sokucanuzelelwa kwenhliziyo. Ukuqunjelwa kwenzeka kaningi, kanti futhi nezinyawo ziyaphazamiseka. Kukhona ukoma emgodini womlomo, kubuhlungu esifundeni se-epigastric. Izinkomba zomsebenzi wokushintsha kwama-enzyme wesibindi, i-jaundice noma i-cholecystitis, i-hepatitis ingakhula.

Kusuka ohlelweni lwezinhliziyo

Uma imithamo yomuthi eyengeziwe ithathwa njalo, khona-ke isigqi senhliziyo siyaphuka, ingcindezi iphakama.

Isistimu yezinzwa ephakathi

Izimo ezivusa inkathazo, izinkinga zokulala, ukuphazamiseka kwengqondo okuncane (isasasa, ukukhathazeka, ukukhathazeka). Ubuhlungu bekhanda nesiyezi kungavela.

Ukusuka ohlelweni lwezinzwa oluphakathi, ikhanda lobuhlungu nesiyezi kungavela.

Engxenyeni yesikhumba namafutha angaphansi

I-Hyperemia yenombolo yangaphandle iyaphawulwa. Isiguli sikhononda “ngokuvutha okukhulu” emzimbeni ophezulu. Kukhona ukuvuvukala okubunjiwe.

Kusuka ohlelweni lwe-hemopoietic kanye ne-heestasis

Kwesinye isikhathi i-leukopenia ne-thrombocytopenia kutholakala ukuthi ine-vasonitis. Ukwakheka kwegazi kuyashintsha. Ngenxa yalesi sizathu, kunconywa ukuthi kuqashwe njalo imingcele ye-biochemical. Kukhona ukopha, kaningi endaweni yomgudu wokugaya ukudla.

Allergies

Kuvela izimpawu zakudala: ukulunywa, ukuqubuka esikhunjeni, i-urticaria ingaqala ukukhula, ukuphefumula kunzima ngenxa yokuvuvukala koxinzelelo. Ukushaqeka kwe-Anaphylactic kutholakala kancane ukuthi kutholakala.

I-Urticaria ingahle ikhule.

Imiyalo ekhethekile

Uma ama-anticoagulants esetshenziswa kanye ne-vasonitis, ukulawulwa kokuqina kwegazi kuyadingeka. Ngaphezu kwalokho, umfutho wegazi kufanele uhlolwe ezigulini ezithambekele kwi-hypo- and hypertension. Iziguli ngemuva kokuhlinzwa zinconyelwa ukulawula izinkomba ezinjenge-hemoglobin, hematocrit. Kufanele kukhunjulwe ukuthi ukubhema kungavusa ukwehla kwezinga lokusebenza kahle kokwelashwa.

Ukuhambisana notshwala

Akunconywa ukusebenzisa izinto eziqukethe utshwala futhi ngasikhathi sinye phuza amaphilisi e-vasonit.

Umthelela ekhonweni lokulawula izindlela

Akunemikhawulo eqinile. Kodwa-ke, uma umuthi uvusa ukuphazamiseka kohlelo lwezinzwa oluyinsakavukela, kuyanconywa ukuthi ugweme imisebenzi edinga ukwanda kokuhlushwa, noma usebenzise ukuqaphela.

Umuthi wenqatshelwe ngesikhathi sokukhulelwa.

Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba

Umuthi uvunyelwe ukusetshenziswa.

Sebenzisa ebudaleni

Kunikezwa umthamo omncane, ngoba ezigulini zaleli qembu kukhona ukwanda kwe-bioavailability yomuthi. Kanye nalokhu, kukhona ukwehla kwenqubo yokumbiwa kwama-pentoxifylline metabolites. Ngokuhlangene, lezi zinto zingaholela ekwandeni kobukhulu bokubonakaliswa kwemiphumela emibi.

Ukweqisa

Ngokunyuka okungalawulwa kwenani le-pentoxifylline, kuvela izimpawu:

• ukozela
• ukwanda kokushisa komzimba;
• ukwehla kwengcindezi, okuboniswa isicanucanu;
• izimo ezethusayo;
• ukwehluleka
• ukopha emgodini wokugaya ukudla, imvamisa yokuhlanza ngento emnyama.

Ngokunyuka okungalawulwa kwenani le-pentoxifylline, ukwanda kokushisa komzimba kwenzeka.

Ngokukhuphuka okungalawulwa kwenani le-pentoxifylline, ukozela kwenzeka.

Ngokukhuphuka okungalawulwa kwenani le-pentoxifylline, kwenzeka ukufeyila.

Okokuqala, ukuhanjiswa kwamathumbu kwenziwa. Ngemuva kwalokho kunikezwa ukwelashwa okubonakalayo.

Ukuxhumana nezinye izidakamizwa

I-ejenti okukhulunywa ngayo inomphumela kuma-anticoagulants, izinto ezibulala amagciwane zeqembu le-cephalosporin, i-valproic acid. Kukhona ukwanda kwezinga lokuphumelela kwezidakamizwa ezinjenge-Insulin, izidakamizwa ezisusa izimpawu ze-hypotension, imithi ye-hypoglycemic yokusetshenziswa komlomo. I-Cimetidine inegalelo ekwandeni kokuxineka kwengxenye esebenzayo eplasma yegazi. Kwenqatshelwe ukusebenzisa ngasikhathi sinye imikhiqizo evela ku-xanthine.

Ama-Analog

Lapho ukhetha umuthi ongabekwa esikhundleni seWasonite, cabanga ngohlobo lwento esetshenziswayo ekwakhiweni kwayo, ekugxileni kwayo. Uhlobo lokukhululwa akuyona into esemqoka, ngoba kuhlala kunethuba lokuphindaphinda umthamo womuthi.

Lapho ukhetha umuthi ongabekwa esikhundleni seWasonite, cabanga ngohlobo lwento esetshenziswayo ekwakhiweni kwayo, ekugxileni kwayo.

Okuwukuphela kokungafani yizimo lapho isiguli sinconywa uhlobo oluthile lomuthi ngezizathu zezokwelapha (ngokwesibonelo, ngesikhathi sokuhlanza noma ubunzima bokugwinya amaphilisi). Indawo yokuqala evame kakhulu phakathi kwezichazayo ingekaVasonit Retard. Okunye ukufaka esikhundleni: Pentoxifylline, Pentoxifylline Zentiva, Trental.

Imibandela yekhefu lekhemisi

Kunikezwa umuthi kadokotela.

Ngingakwazi ukuthenga ngaphandle kadokotela?

Akunakwenzeka ukuthi uthenge ngaphandle kokuthola umuthi. Okuwukuphela kokuthengwa kwemithombo yezinsiza eziku-inthanethi, kepha kulokhu akukho siqinisekiso sobuqiniso nekhwalithi yomuthi.

Inani lentengo yezimbali

Izindleko zezimali okukhulunywa ngazo (ezikhiqizwe e-Ukraine, eRussia noma kwamanye amazwe) ziyefana futhi zifinyelela kuma-ruble angama-430.

Izimo zokugcina zomuthi

Ukushisa kwekamelo okunconyelwe kungaphakathi kuka + 25 ° С.

Akunakwenzeka ukuthi uthenge ngaphandle kokuthola umuthi.

Isikhathi sokuphelelwa yisikhathi

Sebenzisa umuthi kungakapheli iminyaka emi-5 kusukela ngosuku lokukhiqizwa. Ekupheleni kwalesi sikhathi, umuthi ulahlekelwa yizinto zawo, futhi amathuba okuba nemiphumela engalindelekanga ayanda.

Ukubuyekezwa mayelana ne-Wasonite

Ukuhlolwa kwabathengi kwenza lula umsebenzi wokukhetha umuthi ofanele kakhulu.

Odokotela

URuban D.V.

Leli thuluzi libhekana kahle nemisebenzi yalo eyinhloko (ukubuyiselwa kwemoto yezandla namalungu ngokuhlangana kancane kancane, ukuqedwa kwezimpawu ze-atherosclerosis ye-arterial, njll.). Kepha ngifuna ukuqaphela ukuthi ngesikhathi sokwelashwa, imiphumela emibi ihlala ikhula, okuyi -backback ye-Wasonite ngenxa yesidingo sokuphinda ulandise umthamo noma usesha i-analogue engenalo nolaka.

Iziguli

Nikita Ivanov, Alupka

Esikhathini esithile esedlule kwatholakala ukuthi wayenengozi yokuqina kwemizwa. Umphumela wokwelashwa waneliswa ngokuphelele: isiyezi wanyamalala cishe ngokushesha, nobuhlungu bekhanda nabo. Imemori yenziwa yajwayelekile, futhi ngayo, ukucabanga kabusha kwavuselelwa. Kwakuyinhlanhla ukuthi akukho miphumela emibi ngesikhathi sokwelashwa.