I-Gliformin yenzelwe ikakhulukazi ukwelashwa kwesifo sikashukela nokuphazamiseka kwe-metabolic. Njengoba umuthi ungadala ukusabela okubi kakhulu, kunqunywa ngudokotela kuphela.
Igama Lezwe elingafanele
METFORMIN.
I-Gliformin yenzelwe ikakhulukazi ukwelashwa kwesifo sikashukela nokuphazamiseka kwe-metabolic.
I-ATX
Ikhodi yokuhlukaniswa kwamakhemikhali we-anatomical kanye nokwelashwa i-A10BA02.
Khipha amafomu nokwakheka
Umuthi uyatholakala ezibhebheni. Iphilisi eli-1 liqukethe u-0.25 mg we-metformin hydrochloride njengento esebenzayo. Kukhona umthamo we-500, 850, 1000 mg.
Isenzo se-Pharmacological
Amacwecwe afakiwe eqenjini lama-hypoglycemic agents. Iyakwazi ukwandisa ukuthinteka kwezicubu kwe-insulin. Ihlisa ijubane i- gluconeogeneis esibindini. Ama-triglycerides egazini. Umuthi uvame ukunciphisa noma ukuguqula isisindo somzimba sesiguli, yingakho abanye abantu besisebenzisela ukunciphisa isisindo.
Umuthi uvame ukunciphisa noma ukuguqula isisindo somzimba sesiguli, yingakho abanye abantu besisebenzisela ukunciphisa isisindo.
I-Pharmacokinetics
Ukuqoqwa okuphezulu kakhulu kwento esebenzayo kuqashelwa amahora ama-2 ngemuva kokuthatha umuthi. Ihlanganiswe esibindini, izinso, nasezindongeni ze-salivary. Ukuxhumana namaprotheni e-plasma kuncane.
Umuthi ngendlela efanayo uphuma ngosizo lwezinso. Ukuqedwa kwesigamu sempilo kuqala kusuka emahoreni angama-1.5 futhi kungafinyelela amahora angama-4,5.
Yenzelwe ini?
Umuthi unqunywa odokotela emacaleni alandelayo:
- Uhlobo I isifo sikashukela i-mellitus (ukwelashwa kuhlanganiswa nokwelashwa kwe-insulin);
- Uhlobo II isifo sikashukela i-mellitus, uma ukudla bekungasebenzi.
Umuthi ubekelwe iziguli ezinesifo sikashukela sohlobo 1 no-2.
Contraindication
Ukwelashwa ngezidakamizwa akukwazi ukwenziwa uma isiguli sitholakele sinezifo ezilandelayo:
- ukwehluleka kwenhliziyo, ingozi ye-cerebrovascular, ukwehluleka ukuphefumula kanye ne-infyoction ye-myocardial;
- isifo sikashukela nesifo sokuwa;
- i-lactic acidosis;
- isifo sikashukela sikashukela;
- izinqubo ezinzima zokutheleleka, ukomisa kanye ne-hypoxia.
Isiguli akufanele siphathwe ngomuthi uma kunokuphazamiseka kwento esebenzayo. Ukusetshenziswa kwemithi ngesikhathi sokungenelela kokuhlinzwa ngokuqokwa kokulashwa kwe-insulin akunconyiwe.
Uma kunezinambuzane emathunjini, isinqumo sokuphuza umuthi kufanele senziwe udokotela.
Ngokunakekela
Ukuqokwa akunconywa kubantu abasebenza kanzima ngokomzimba, ngoba ukuthuthukiswa kwe-lactic acidosis kungenzeka.
Ungayithatha kanjani i-gliformin?
Ukuthatha umuthi wesifo sikashukela
Umthamo ukhonjiswa ngudokotela ngokwahlukana, kuye ngezinga le-glucose egazini lesiguli. Umthamo ekuqaleni ukwelashwa uvame lokhu: 0.5-1 g ngosuku noma 0,85 g kanye ngosuku. Ngemuva kwezinsuku eziyi-10-15 zokwelashwa, lo mgamo ungakhuphuka ngokuya ngezinga le-glycemia. Umthamo wokulondolozwa ngu-1.5-2 g ngosuku. Isikhathi sokwelashwa esidingekayo ukuqinisa impilo yesiguli sikhonjiswa ngudokotela futhi singaguqulwa nguye phakathi nokwelashwa.
Ithebhulethi zidakwa kakhulu ngesikhathi sokudla noma ngemuva kokudla, futhi akufanele lihlafunwe. Udinga ukuphuza amaphilisi ngamanzi anele.
Ngesikhathi sokulashwa, udokotela kufanele aqaphe izinga likashukela wegazi lesiguli.
Ukwehla kwesisindo
Umuthi ocwazimulayo uvame ukusetshenziswa ngabesifazane. Imishini kuleli cala imi kanjena: isidakamizwa senza umsebenzi we-insulin uqonde, futhi ukuthathwa kwe-glucose kulungile. Ngenxa yalokhu, ungqimba lwamafutha aluqongeli. Uma owesifazane enquma ukunciphisa umzimba ngosizo lwamathebulethi, lokhu kufanele kwenziwe ngokucophelela, ungakhohlwa ukuthi kubalulekile ukubonana nodokotela, ngaphandle kwalokho ungalimaza impilo yakho.
Imiphumela emibi yeGliformin
Amapheshana wesisu
Isiguli singathola ukugabha, isicanucanu, ukunambitheka kwensimbi emlonyeni, ukuhuda, nobuhlungu besisu. Izimpawu ezinjalo zenzeka ikakhulukazi ekuqaleni kokwelashwa futhi kamuva zinyamalale. Ukwenza lula ukubonakaliswa, ungabeka ama-antacid noma ama-painkillers.
Kusukela epheshaneni lesisu, ukugabha, uhudo nobuhlungu besisu kungavela njengemiphumela emibi.
Izitho zeHematopoietic
Mhlawumbe ukuthuthukiswa kwe-megaloblastic anemia.
Ngasohlangothini lwe-metabolism
Uma isiguli sikhula nge-lactic acidosis, ukwelashwa kufanele kuphele ngokuphelele. Ngokulashwa isikhathi eside ngomuthi, ukumunca okugcwele kwe-cyanocobalamin kungaphazamiseka.
Kusuka ohlelweni lwezitho zofuzo
Ukuboniswa akuvamile.
Uhlelo lwe-Endocrine
I-Hypoglycemia kungenzeka lapho usebenzisa umuthi ku-dosage engalungile.
Ukusuka ohlelweni lwe-endocrine, i-hypoglycemia kungenzeka lapho usebenzisa umuthi kumthamo ongalungile.
Allergies
Ukuqhuma kwesikhumba kungenzeka.
Umthelela ekhonweni lokulawula izindlela
Uma i-monotherapy yenziwa nomuthi, ayithinti amandla okugxila. Uma sisetshenziswa ngokubambisana neminye imithi yesifo sikashukela, njenge-insulin, leli khono lingaphazamiseka.
Imiyalo ekhethekile
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Awukwazi ukuphuza umuthi lapho uthwala ingane futhi uncelisa ibele. Idatha yokungena kobisi lwebele ayitholakali. Uma owesifazane ekhulelwe ngenkathi ephuza umuthi, kubalulekile ukukhansela ukwelashwa kwabo futhi unikeze nokwelashwa kwe-insulin.
Awukwazi ukuphuza umuthi lapho uthwala ingane futhi uncelisa ibele.
Kunquma uGliformin ezinganeni
Kunqunywe ezimweni ezingavamile ebuntwaneni (ingane kumele okungenani ibe neminyaka eyi-10).
Sebenzisa ebudaleni
Ezigulini ezineminyaka engaphezu kwengama-60 ubudala, ukusetshenziswa komuthi kufanele kwenziwe ngokuqapha, ngoba kunamathuba amaningi okukhula kwe-lactic acidosis.
Isicelo sokusebenza kokulimala kwezinso
Ayikwazi ukusetshenziselwa ukwehluleka okunamandla kwezinso.
Ayikwazi ukusetshenziselwa ukwehluleka okunamandla kwezinso.
Sebenzisa umsebenzi wesibindi okhubazekile
Ukulimala kwesibindi okukhulu kuyisizathu sokwenqabela ukusetshenziswa komuthi ngezinhloso zokwelapha.
I-Gliformin Overdose
I-Lactic acidosis kungenzeka, umphumela wayo kwesinye isikhathi uyabulala. Izimpawu zokuqala zale ndlela zibonisa ngobuthakathaka obujwayelekile, ubuhlungu bemisipha, ukwehla kwezinga lokushisa, isicanucanu nokuhlanza, nokushaya kwenhliziyo okuhamba kancane. Kamuva kungavela isiyezi, ukwazi ukungasebenzi kahle nethokomele.
Amacala we-overdose yisizathu sokulaliswa esibhedlela okuphuthumayo kwesiguli. Ukwelashwa okubonakalayo kuyadingeka.
Ukuxhumana nezinye izidakamizwa
Ama-hormone we-thyroid, izindlela zokuvimbela inzalo ngomlomo, okuphuma ku-nicotinic acid, kanye ne-loop diuretics kunganciphisa umphumela we-hypoglycemic umuthi.
I-Cimetidine ibambezela ukuqedwa okujwayelekile komuthi emzimbeni.
I-Cimetidine ibambezela ukuqedwa okujwayelekile komuthi emzimbeni.
Ukuqiniswa komphumela okhiqizwe ngomuthi kuyabonakala lapho kuthathwa i-cyclophosphamide ne-mao inhibitors.
Umuthi ungawenza buthaka umphumela we-coumarin derivatives.
Ukuhambisana notshwala
Akunconywa ukuhlanganisa ukwelashwa notshwala, ngakho-ke kufanele wenqabe ukuphuza utshwala.
Ama-Analog
Umuthi ungashintshwa nezidakamizwa ezifana neSiofor, iFommetin, isifo sikashukela, i-Glucofage ne-Glucofage Long, iMetformin nomuthi obizwa ngeProlong (umthamo wokwelashwa - 750 mg ngosuku).
Imibandela yekhefu lekhemisi
Ngokusebenzisa umuthi kuphela. Isiguli kufanele sifunde imiyalo esetshenzisiwe.
Kubiza malini?
Intengo yomuthi iqala kusuka kuma-ruble angama-300.
Izimo zokugcina zomuthi
Ukushisa kwesitoreji kufanele kube emazingeni okushisa asekamelweni, kungcono ukugcina umuthi endaweni emnyama.
Isikhathi sokuphelelwa yisikhathi
Iminyaka emithathu
Umkhiqizi
I-Akrikhin, eRussia.
Ukubuyekezwa mayelana neGliformin
Odokotela
A.L. UDolotova, udokotela ojwayelekile, uKrasnoyarsk: "Umuthi uyasebenza empini yokulwa nesifo sikashukela sohlobo 2, cishe akukho okungahambi kahle."
R.Zh. USinitsina, udokotela ojwayelekile, uNorilsk: "Ngibheka lesi sidakamizwa njengesihle kakhulu ekulweni nesifo sikashukela. Amandla amahle kakhulu."
Impilo yeshalofu yesidakamizwa yiminyaka emi-3.
Iziguli
U-Irina, oneminyaka engama-34, uBryansk: "Umuthi usize ukuqinisa isimo somzimba kushukela. Izindleko ziphansi, impilo iyathuthuka masisha, ngakho-ke ngiyasincoma."
UGeorge, oneminyaka engama-45, u-Yoshkar-Ola: "Welashwa ngekhambi lesifo sikashukela. Lesi sifo asizange siphele ngokuphelele, kepha saba lula kakhulu."
Ukulahlekelwa isisindo
U-Angelina, oneminyaka engama-25, uVladimir: "Ngakwazi ukunciphisa umzimba ngokubonga umuthi, okuyinto engangijabulisa ngawo. Ukuwusebenzisa kwawo akuyona ingozi emzimbeni, uma uthintana nodokotela."
UNina, oneminyaka engama-40, eMoscow: "Angikwazi ukunciphisa umzimba isikhathi eside. Ngemuva kwalokho ngaya kudokotela, wachaza ukuthi yini inkinga futhi wawunquma lo muthi. Isisindo sehlile."
