Imiphumela yokusetshenziswa kwe-Neurobion kushukela

I-Neurobion isidakamizwa sanamuhla se-multivitamin. Umphumela wokwelapha umuthi ubangelwa i-thiamine, i-pyridoxine ne-cyanocobalamin. Odokotela bavame ukunquma umuthi wokwelapha izifo zohlelo lwezinzwa.

I-ATX

I-A11DB (Vitamin B1, B6 ne-B12).

I-Neurobion isidakamizwa sanamuhla se-multivitamin.

Khipha amafomu nokwakheka

Emakethe yezokwelapha yezwe lethu, umuthi ungathengwa kumathebulethi nakuma-ampoule ayi-3 ml.

Amaphilisi

Amacwecwe yi-biconvex, embozwe ngegobolondo emhlophe ecwebezelayo ngaphezulu. Ukwakheka kwamakhemikhali kwesidakamizwa kuvezwa ematafuleni.

Amacwecwe yi-biconvex, embozwe ngegobolondo emhlophe ecwebezelayo ngaphezulu.

Isixazululo

Umuthi wokusetshenziswa kwabazali uwuketshezi obomvu osobala.

Isenzo se-Pharmacological

Amavithamini eqembu B, afakiwe ekwakhekeni komuthi, enza izinqubo ze-redox, alawule ukusebenza kwe-lipids, amaprotheni kanye nama-carbohydrate. Lezi zingxubevange, ngokungafani nama-analog-soluble analogue, azifakwanga emzimbeni womuntu, ngakho-ke, kumele zibe khona njalo futhi ngamanani anele zingena emzimbeni ngokudla noma njengengxenye yezithako ezinovithamini. Ngisho nokuncipha kwesikhashana kokudla kwabo kwenza buthaka imisebenzi yezinhlelo ze-enzyme, ezivimbela ukusabela kwe-metabolic futhi kunciphise ukungatheleleki komzimba.

Amavithamini eqembu B, afakwe ekwakhekeni komuthi, izinhlungu ze-redox.

I-Pharmacokinetics

Ngokushoda kwe-thiamine emzimbeni, inqubo yokuguqulwa kwe-pyruvate ku-acetate acid (acetyl-CoA) iyaphazamiseka. Ngenxa yalokhu, ama-keto acid (α-ketoglutarate, puruvate) aqongelela egazini nasezicutshweni zezitho zomzimba, okuholela "ekuqinisekisweni" komzimba. I-acid iyakhula ngokuhamba kwesikhathi.

I-bioactive metabolite ye-vithamini B1, i-thiamine pyrophosphate, isebenza njenge-non-protein cofactor ye-decarboxylases ye-pyruvic ne-α-ketoglutaric acid (i.e.obamba iqhaza kwi-catalysis ye-carbohydrate oxidation). I-Acetyl-CoA ifakiwe kumjikelezo weKrebs futhi ihlinzekwa ngamanzi ne-carbon dioxide, ngenkathi ingumthombo wamandla. Ngasikhathi sinye, i-thiamine hydrochloride ibandakanyeka ekwakhekeni kwamafutha acid ne-cholesterol, isebenza inqubo yokuguqula ama-carbohydrate abe ngamafutha.

Lapho ihanjiswa ngomlomo, isigamu sokuphila se-Vitamin B1 cishe amahora angama-4.

Lapho ihanjiswa ngomlomo, isigamu sokuphila se-Vitamin B1 cishe amahora angama-4. Esibindini, i-thiamine i-phosphorylated futhi iguqulwa ibe yi-thiamine pyrophosphate. Umzimba womuntu omdala uqukethe cishe ama-30 mg we-vithamini B1. Uma kunikezwe imetabolism enkulu, ikhishwa emzimbeni ngaphakathi kwezinsuku ezingama-5-7.

I-Pyridoxine iyingxenye yesakhiwo sama coenzymes (pyridoxalphosphate, pyridoxamine phosphate). Ngokushoda kwe-Vitamin B6, ukushintshwa kwama-amino acid, ama-peptides namaprotheni kuyaphazamiseka. Egazini, inani lamaseli abomvu egazi liyancipha, i-hemostasis iyaphazamiseka, isilinganiso samaphrotheni we-serum siyashintsha. Ezimweni ezisezingeni eliphakeme kakhulu, ukuntuleka kwamavithamini ancibilikiswa amanzi kuholela ekushintsheni kwe-pathological esikhunjeni. Umzimba uqukethe cishe i-150 mg ye-pyridoxine.

Ngokushoda kwe-Vitamin B6, ukushintshwa kwama-amino acid, ama-peptides namaprotheni kuyaphazamiseka.

I-Pyridoxalphosphate ibandakanyeka ekwakhekeni kwama-neurotransmitters nama-hormone (i-acetylcholine, i-serotonin, i-taurine, i-histamine, i-tryptamine, i-adrenaline, i-norepinephrine). I-Pyridoxine futhi isebenzisa i-biosynthesis ye-sphingolipids, izakhi zesakhiwo se-myelin sheaths ye-nerve fibers.

ICyanocobalamin iyi-Vitamin equkethe insimbi esheshisa ukwakheka kwamangqamuzana abomvu egazi, isebenze ama-enzyme wesibindi enza ukuthi ukuguqulwa kwama-carotenoids kube yi-retinol.

IVithamini B12 iyadingeka ekuhlanganiseni kwe-deoxyribonucleic acid, i-homocysteine, i-adrenaline, i-methionine, i-norepinephrine, i-choline ne-creatine. Ukwakheka kwe-cyanocobalamin kufaka phakathi i-cobalt, iqembu le-nucleotide kanye ne-cyanide radical. Vitamin B12 ifakwa ikakhulukazi esibindini.

IVithamini B12 iyadingeka ekuhlanganiseni kwe-deoxyribonucleic acid.

Izinkomba zokusetshenziswa

Umuthi ubekelwe ukwelashwa kwama-pathologies alandelayo:

• i-radiculopathy;
• thoracalgia;
• izifo zomgogodla (spondylarthrosis, osteochondrosis, spondylosis);
• isifo se-neuropathic;
• i-herpes zoster;
• i-trigeminal neuralgia;
• i-lumbar syndrome;
• I-Bell palsy;
• plexopathy.

Contraindication

Umuthi unezinto eziningi eziphikisana nokuqokwa:

• i-thromboembolism;
• iminyaka yezingane;
• i-erythremia;
• hypersensitivity;
• isilonda sesisu;
• ukungezwani komzimba

Umuthi ubekelwe i-thoracalgia.

Isifo se-Neuropathic yisizathu sokuqokwa komuthi.

Nge-herpes zoster, iNeurobion ihamba phambili.

I-Trigeminal neuralgia yisifo lapho kuthathwa khona i-neurobion.

I-Neurobion imiselwe i-Bell paralysis.

Nge-plexopathy, kuthathwa i-neurobion.

I-Neurobion imiselwe i-radiculopathy.

Ungayithatha kanjani

Ukuvimbela ukwenzeka kokubuyela kwesifo kabusha, umuthi unqunywe ngefomu lethebhulethi, 1 i-capsule izikhathi ezi-3 ngosuku. Lapho uthatha amaphilisi, udinga ukuwaphuza namanzi amaningi. Isikhathi senkambo yokwelashwa sinqunywa ngudokotela.

Umuthi kuma-ampoules uphinde wabelwe ukuphathwa kwemithambo yegazi. Ngaphambi kokususa izimpawu eziphambili zesifo, kunconywa ukuthi ufake umuthi isikhathi esisodwa ngosuku. Ngemuva kokuzizwa ungcono, imijovo yenziwa kanye ngesonto amasonto ama-2-3.

Ngoshukela

Ithuluzi elingenhla lilungile ekwelapheni izinhlungu ze-neuropathic ezigulini ezinesifo sikashukela se-polyneuropathy. Kwatholakala ukuthi umuthi unciphisa ubukhali be-paresthesia, ithuthukisa ubuciko bokubukeka kwesikhumba, ikhulula izinhlungu.

Ukuvimbela ukwenzeka kokubuyela kwesifo kabusha, umuthi unqunywe ngefomu lethebhulethi, 1 i-capsule izikhathi ezi-3 ngosuku.

Imiphumela emibi

Umuthi ubekezelelwa kahle iningi leziguli. Kodwa-ke, kwezinye izimo, ukubonakaliswa kwemiphumela emibi ehlukaniswe ngamaqembu kungenzeka.

Amapheshana wesisu

• ukugwinya;
• ukuhlanza
• iziqubu zamathumbu;
• Ubuhlungu besisu;
• isicanucanu
• ukuthopha;
• isifo sohudo

Kusuka emasosheni omzimba

• I-edema kaQuincke;
• dermatitis;
• eczema
• ukusabela kwe-anaphylactoid.

Allergies

• ukuqhuma
• ukulunywa
• hyperemia;
• ukujuluka ngokweqile;
• izinhlungu
• induna
• i-urticaria;
• i-necrosis endaweni yomjovo.

Lapho uthatha umuthi kungadala i-nausea, ukuhlanza.

Eminye yemiphumela emibi yokuthatha i-Neurobion uhudo.

Ukuqunjelwa, ukulunywa, isikhumba - imiphumela emibi ethatha umuthi.

Lapho uthatha i-Neurobion, ukujuluka ngokweqile kungenzeka.

Ngesikhathi sokulashwa nge-Neurobion, ukuvela kokushaya kwenhliziyo okusheshayo, izinhlungu zenhliziyo zingavela.

Lapho uthatha umuthi, isiyezi kungenzeka.

Ukudangala, i-migraine - imiphumela emibi yokuthatha i-Nerobion.

Uhlelo lwenhliziyo

• ukuzindla kwenhliziyo;
• izinhlungu esifubeni.

Uhlelo lwezinzwa

• Hyper irritability;
• i-migraine
• i-sensor neuropathy;
• i-paresthesia;
• Ukudana
• isiyezi.

Imiyalo ekhethekile

Umuthi awuhloselwe ukuphathwa kwe-intravenous. Futhi, umuthi awukwazi ukusetshenziswa kwiziguli ezinesifo senhliziyo esibuhlungu. Ngokuqapha ngokweqile, umuthi kufanele unikezwe abantu abane-neoplasms enobungozi.

Umuthi awuhloselwe ukuphathwa kwe-intravenous.

Umthelela ekhonweni lokulawula izindlela

Umuthi awuthinti amandla omuntu okushayela izimoto nezindlela eziyinkimbinkimbi.

Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba

Ngesikhathi sokuzala, umkhiqizo ungasetshenziswa kuphela uma kunezimpawu ezicacile zokuntuleka kwamavithamini B1, B6 kanye ne-B12 emzimbeni womama okhulelwe. Umphumela womuthi ekukhulelweni, ngaphambi kokukhulelwa nangemva kokubeletha kwengane awukasungulwa.

Udokotela kumele anqume ukufaneleka kokunquma umuthi ngesikhathi sokukhulelwa, anqume ubudlelwane phakathi kwezinzuzo ezingaba khona kanye nengozi.

Amavithamini akha isidakamizwa adalulwa ngemfihlo yezindlala zezilwane ezincelisayo, kepha nokho, ingozi ye-hypervitaminosis ezinganeni ayikasungulwa. Ukwemukelwa kwe-pyridoxine kwimithamo ephezulu (> 600 mg ngosuku) kungavusa i-hypo- noma i-agalactia.

Ngesikhathi sokuzala, umkhiqizo ungasetshenziswa kuphela uma kunezimpawu ezicacile zokuntuleka kwamavithamini B1, B6 kanye ne-B12 emzimbeni womama okhulelwe.

Ukuqokwa kwe-neurobion ezinganeni

Izingane ezingaphansi kweminyaka engu-15 ubudala azinconywa ukuba zinikeze umuthi.

Sebenzisa ebudaleni

Imininingwane yokusetshenziswa kwalesi sidakamizwa kubantu abadala nase-senile ayitholakali.

Ukweqisa

Ezincwadini ezikhethekile, kuchazwa amacala okweqisa kwemithi engalapheki. Iziguli zikhononda ngempilo engeyinhle, izicubu zomzimba, amalunga, isicanucanu nokukhathala okungapheli. Uma uthola lezi zimpawu ezingenhla, umuthi kufanele ukhanselwe bese uthintana nodokotela. Uzothola imbangela yezinkinga, anikeze usizo lwezimpawu.

Vitamin B1

Ngemuva kokwethulwa kwe-thiamine kudosi elingaphezu kokunconyiwe izikhathi ezingaphezu kwe-100, i-hypercoagulation, ukungasebenzi kahle kwe-purine metabolism, imiphumela ye-curariform ganglioblocking ebangela ukuhanjiswa okungahambi kahle kwezihibe ngasentanjeni yezinzwa yabonwa.

Ukuzizwa ungasebenzi, ubuthakathaka obujwayelekile buwuphawu lokusebenzisa ngokweqile umuthi.

Vitamin B6

Ngemuva kokumukelwa isikhathi eside (izinyanga ezingaphezu kweziyisithupha) ze-pyridoxine ngethamo elingaphezu kwama-50 mg / ngosuku, ukubonakaliswa kwemiphumela ye-neurotoxic (hypochromasia, seborrheic eczema, isithuthwane, i-neuropathy ene-ataxia) kungenzeka.

Vitamin B12

Uma kwenzeka kuba ne-overdose, kuqubuka imizwa yokungezwani komzimba, i-migraine, ukuqwasha, umqubuko, umfutho wegazi ophakeme, ukulunywa, ukushuba kwemikhawulo engezansi, isifo sohudo, i-anemia kanye ne-anaphylactic.

Ukuxhumana nezinye izidakamizwa

Imiyalo esetshenzisiwe ikhombisa ukuthi ezinye izidakamizwa azihambelani nomuthi ongenhla. Kwesinye isikhathi, ukuphathwa okuhambisanayo kuholela ekunciphiseni umthelela wokwelapha noma ukwanda kokubonakaliswa kwemiphumela emibi:

1. I-Thiamine ibhujiswa ngokusebenzisana nemithi equkethe i-sulfites (potassium metabisulfite, potassium bisulfite, sodium hydrosulfite, sodium sulfite, njll.).
2. Ukusetshenziswa okuhlangene kwe-cycloserine ne-D-penicillamine kukhulisa isidingo somzimba we-pyridoxine.
3. Umuthi akufanele uhlanganiswe neminye imithi yesirinji efanayo.
4. Ukuphathwa kwe-diuretics kuholela ekwehleni kwenani le-vithamini B1 egazini futhi kusheshise kakhulu ukuphuma kwalo yizinso.

Umuthi akufanele uhlanganiswe neminye imithi yesirinji efanayo.

Isiguli kufanele sazise udokotela ngemithi ayiphuzayo njengamanje. Udokotela kulokhu uzolungisa irejimithi yokwelashwa, ngaleyo ndlela anciphise amathuba emiphumela emibi.

Ama-Analog

Uma kunesidingo, umuthi ungathathelwa indawo izindlela ezinjengokuthi:

• Neurolek;
• Kombilipen;
• Milgma
• IVitaxone;
• I-Neuromax;
• Kuvumelekile;
• I-Neuromultivitis;
• Esmin;
• I-Neurobeks-Teva;
• I-Selmevite;
• Dynamizan;
• I-Unigamm
• Kombilipen;
• I-Centrum;
• I-Pantovigar;
• I-Farmaton
• UGinton;
• I-Nerviplex;
• I-Aktimunn;
• I-Berocca plus;
• Encaps;
• I-Detoxyl
• I-Pregnakea;
• I-Neovitam;
• yinkimbinkimbi yamavithamini B1, B12, B6;
• Megadine;
• I-Neurobeks-Forte.

I-Neuromax iyi-analogue engalungile yeNeurobion.

Esikhundleni seNeurobion, ungathatha i-Revalid.

I-Neuromultivitis iyi-analogue yeNeurobion.

IPantovigar inomphumela ofanayo wemithi njengeNeurobion.

ICombiplane ithathwa njenge-analogue yeNeurobion.

IMilgamm iqukethe into efanayo esebenzayo njengeNeurobion.

Umkhiqizi

Umakhi osemthethweni walesi sidakamizwa nguMerck KGaA (Germany).

Imibandela yekhefu lekhemisi

Kumakhemisi, leli khambi lihanjiswa ngemithi ethile, kepha akusona isidakamizwa esikhonjelwe ngokuqinile.

Intengo yeNeurobion

Izindleko zomuthi e-Russia ziyahlukahluka kuhla lwamanani kusuka kuma-ruble angama-220 kuya kwangama-340. E-Ukraine - 55-70 UAH. ukupakisha.

Izimo zokugcina zesidakamizwa i-Neurobion

Gcina umuthi endaweni emnyama futhi epholile.

Isikhathi sokuphelelwa yisikhathi

Iminyaka emithathu

Ukubuyekezwa kodokotela neziguli mayelana Neurobion

USvetlana oneminyaka engama-39 ubudala, eKiev: "Izinkinga zomgogodla bezilokhu ziphazamisa kusukela ngineminyaka engu-18 ubudala. Kwatholakala ukuthi u-Osteochondrosis udokotela wanikeza amavithamini imijovo. Umuthi walimunca intramuscularly, i-ampoule eyi-1 ngosuku. Ngemuva kwesifundo sokwelashwa okwathatha amasonto amabili, impilo yami yathuthuka. Ngezinjongo ze-prophylactic, ngisebenzisa umuthi okwifomu lethebhulethi.

U-Andrei oneminyaka engama-37, u-Astrakhan: "Muva nje baqale ukukhathazeka ngokulunywa kakhulu nobuhlungu endaweni yemisipha. Eseqokelwe udokotela, uthole ukuthi ngine-radicular neuritis. Udokotela wamachaphaza wemizwa wafaka imijovo yeNeurobion.Ukungaphatheki kahle konke kwahamba ngokushesha.Nezinsuku ezine lo muthi wawuphathwa nsuku zonke. Ngemuva I-ampoule eyi-1 ngesonto inqunyelwe. Ngigculisekile ngemiphumela yokwelashwa. "

USabina oneminyaka engama-30, eMoscow: "Ngasebenzisa amavithamini e-lumbar neuralgia isikhathi eside. Ngemuva kwesikhashana, bayeka ukusiza. Lapho ngiya kudokotela, wajova i-Neurobion. Ngemuva kwezinsuku ezimbalwa ngakhululeka. Ngemuva kokululama, ngizophinde ngiyisebenzise njenge-prophylactic. umuthi ngesimo sezibhebhe. "

U-Artyom oneminyaka engama-25 ubudala, uBryansk: "Usebenzise i-vitamin complex ekwelapheni i-neuro-brachial syndrome. Wayenikeza imijovo nsuku zonke ngezinsuku ezinhlanu. Umuthi udambise ukuhlaselwa kobuhlungu futhi ubuyise umzimba ngenani lamavithamini adingekayo .. Ngemuva kwezifundo ezathatha amasonto amathathu, udokotela owayemele amaphilisi wawasebenzisa ngokuqhubekayo. isetshenziswe njengokwelashwa kwesondlo ukuvikela ukubuyela emuva. "