I-cholesterol ethe xaxa ku-plasma yegazi kungenye yezinkinga ezivame kakhulu ezitholakala emhlabeni wanamuhla kubantu.
I-cholesterol ethe xaxa egazini ingadala ukukhula kwenqwaba yezifo nama-pathologies emzimbeni. Uma kwenzeka kwephulwa umthetho we-lipid metabolism oboniswe ngokwanda kokuqukethwe kwe-lipids emzimbeni, kufanele uthinte isikhungo sezokwelapha ngokushesha futhi wenze uhlolo olufanele ukunquma inkambo yokwelashwa.
Ngenqubo yokwelapha, kusetshenziswa izidakamizwa ezahlukahlukene. Enye yezidakamizwa zesimanje kakhulu i-Lipantil.
Ngaphambi kokuthenga isidakamizwa i-Lipantil, kufanele uthintane nodokotela wakho, ufunde imiyalo yokusebenzisa, intengo kanye nokubuyekezwa kweziguli ezihlole ukusebenza ngempumelelo kwalesi sidakamizwa ekulweni ne-cholesterol ephezulu ku-plasma yegazi.
Imininingwane ejwayelekile mayelana nomuthi
Umuthi ukhiqizwa ngumenzi ngesimo samaphilisi.
Amaphilisi we-gelatin anombala onsundu ngombala. Okuqukethwe kuvezwa ngesimo se-powder enombala omhlophe noma ocishe ube mhlophe.
Ithuluzi elingelolezokwehlisa izidakamizwa - iqembu lama-fibrate.
Imithi ingathengwa emakhemisi kuphela ngemithi evela kudokotela wakho.
Impilo yasemashalofini yeLepantil 200 M iyiminyaka emi-3 ngemuva kosuku lokuphela kwalo muthi onqatshelwe ukulusebenzisa. Umuthi ophelelwe yisikhathi kufanele ulahlwe.
Amakhebuli agcwele ku-PVC / Al blims of izingcezu eziyi-10 ebhulini elilodwa. Amabhulawu amathathu agcwele emaphepheni amakhadibhodi. Imiyalo yokusebenzisa umuthi ifakwe kula mapakeji.
Ngokungezelela ngamabhulukwe anamakhompiyutha ayi-10, umenzi uphinde akhiqize izishizi ezinamakhompiyutha ayi-15 eLipantil 200. Amabhuthi amabili anjalo afakiwe kwiphakheji nesiqondisi sokusebenzisa.
Gcina umuthi ekushiseni kwama-degree Celsius angama-15 kuye kwangama-25. Indawo yokubeka kufanele ingabi kude nezingane nezilwane ezifuywayo, futhi kufanele ivikelwe elangeni.
Izwe okuvela kulo muthi yiFrance. Ukukhiqizwa kwalesi sidakamizwa kwenziwa yinkampani i-Resifarm Fontaine.
Intengo yesidakamizwa emakhemisi e-Russian Federation isuka kuma-780 kuya kuma-ruble ayi-1000
Ukubuyekezwa kwabantu abasebenzise i-Lipantil ngezinhloso zokwelapha kuyinto enhle kakhulu, engakhombisa ukusebenza kahle kwemithi.
Futhi, iziguli eziningi kuzibuyekezo zazo ziphawula amathuba aphansi wemiphumela emibi lapho sisebenzisa umuthi.
Izinkomba kanye ne-contraindication, imiphumela emibi
I-Lipantil iyisidakamizwa esinciphisa i-lipid, isithako esiyinhloko esisebenzayo somuthi yi-Finofibrate. Isithako esisebenzayo sisebusweni le-gelatin elifomu elinemicronized.
I-Fenofibrate ithuthukisa i-lipolysis kanye nokususwa kwe-lipoprotein ye-atherogenic kusuka ku-plasma, lapho kunokuqukethwe okuphezulu kwe-triglycerides.
Isakhi esisebenzayo esiyinhloko sisuselwa ku-fibric acid.
Ngokwengeziwe kule ngxenye, izinhlanganisela zamakhemikhali ezilandelayo zikhona ekwakhiweni kwomuthi:
- isitashi pregelatinized;
- i-lactose monohydrate;
- i-sodium lauryl sulfate;
- i-magnesium stearate;
- i-crospovidone;
- i-gelatin;
- titanium dioxide;
- Udayi omelwe yi-iron oxide E172.
Inkomba esetshenziswayo yikhona kokuba khona kwesiguli se-hypercholesterolemia kanye ne-hypertriglyceridemia eyedwa noma exubekile (uhlobo lwe-dyslipidemia IIa, IIb, III, IV).
Umuthi kufanele usetshenziswe ezimweni lapho ukusetshenziswa kokudla nezinye izindlela zokulawula ezingezona izidakamizwa kungasebenzi noma kungasebenzi.
Ngesikhathi sokwelashwa ngeLipantil, ukudla okwasungulwa ngaphambilini kufanele kubhekwe ngokuqinile.
Contraindication ukusetshenziselwa amacala alandelayo:
- Ukuba khona kokuzwela okwengeziwe komzimba wesiguli ukuze kufenofibrate noma okunye ukuhlangana kwamakhemikhali okwakha umuthi.
- Ukuba khona kokwehluleka okukhulu kwezinso emzimbeni.
- Ukwehluleka kwesibindi okukhulu, kufaka phakathi ukuthuthukiswa kwe-cirrhosis.
- Iminyaka yesiguli ingaphansi kweminyaka eyi-18.
- Ukuba khona kwezifo ezihambisana nomsebenzi we-gallbladder okhubazekile.
- Ukuba khona emzimbeni we-congenital galactosemia, ukuntuleka kwe-lactase nokulimala kwe-glucose kanye nezinqubo zokufakwa kwe-galactose.
Ngokuqapha, kufanele usebenzise umuthi uma isiguli sinezimpawu ze-hypothyroidism. Ngaphezu kwalokho, ukuqaphela ekusebenziseni kuyadingeka lapho isiguli sisebenzisa kabi utshwala. Futhi ngesikhathi sokwelashwa kweziguli esezikhulile.
Ngesikhathi sokukhulelwa nokukhishwa kwengqondo, isinqumo sokusebenzisa umuthi kufanele senziwe udokotela oholayo ngesisekelo sokucwaninga okugcwele kwemininingwane yocwaningo etholakalayo emzimbeni wesiguli.
Imiyalo yokusebenzisa umuthi
Umuthi uthathwa ngokuhambisana nemiyalo yokusebenzisa, i-capsule eyodwa ngosuku ngesikhathi sokudla main.
Isikhathi sokwelashwa sinqunywa udokotela, ebheka imiphumela yokuhlaziya, ukuhlolwa kanye nezimpawu zomzimba womuntu ngamunye.
Umuthi kumele uphuzwe isikhathi eside, ngenkathi ubheka izidingo ezinqunywe ngudokotela ovela kwezokudla okudla.
Uma ungekho umphumela wokwelapha obonakalayo ngemuva kwezinyanga ezimbalwa ngemuva kokuqala kwenkambo yokuphuza umuthi kufanele ucabangele ukulungela ukusetshenziswa kwawo okunye. Imvamisa, isikhathi sesifundo okungenani izinyanga ezintathu.
Lapho kungekho khona amandla amahle, umbuzo wokusebenzisa enye i-concomitant noma enye indlela yokusebenza uyaxazululwa.
Ngesikhathi sokulashwa, umuntu angathola imiphumela emibi ngokuthatha i-Lipantil.
Ngokuvamile, imiphumela emibi ibonakaliswa yile nkinga elandelayo:
- Engxenyeni yendlela yokugaya ukudla - Ubuhlungu besisu, isicanucanu, ukunxusa ukuthi ungaphalaza, uhudo, ukuthokomala. Ezimweni ezingavamile, ukuthuthukiswa kwe-pancreatitis eyingozi nokubukeka kwamagallstones kungenzeka.
- Engxenyeni yesikhumba - ukuqubuka kwesikhumba, ukulunywa, i-urticaria, ezimweni ezingavamile, i-alopecia.
- Ukusuka ohlangothini lohlelo lwe-musculoskeletal ezimweni ezingavamile, ukuthuthukiswa kokuphazamisa i-myalgia, i-myositis, ukuqina kwemisipha nobuthakathaka bemisipha kungenzeka.
- Kusukela ohlangothini lwesistimu yezinhliziyo, ukuthuthukiswa kwe-venous thromboembolism kungenzeka.
- Kusukela ohlangothini lwesistimu yezinzwa ephakathi, kungaba khona umphumela oseceleni wekhanda nokungasebenzi ngocansi.
Ngaphezu kwalokho, ukusetshenziswa komuthi kungathinta imiphumela yokuhlolwa kwelebhu. Njengomphumela wokusetshenziswa kweLipantil, ukukhuphuka okulinganiselayo emsebenzini wama-transaminases kanye nokwanda kokuhlungwa kwe-creatine ene-urea ku-serum yegazi kungabonakala.
Ezimweni ezingandile, kungavela ukwanda kwe-hemoglobin nokubalwa kwamangqamuzana amhlophe egazi.
I-overdose ne-lipantil analogues
Amacala okweqa ngokweqile lapho uthatha umuthi awaziwa, futhi i-antidote ethile ayaziwa. Uma kwenzeka izinsolo zokweqisa kwe-overdose, kunikezwa izimpawu zokwelashwa ezisekelayo. Inqubo ye-hemodialysis kuleli cala ayisebenzi.
I-Fenofibrate uma ithathwa ngokuhlangana nama-anticoagulants omlomo, ingakhuphula umphumela wokugcina, onomthelela ekwandeni okukhulu kwengozi yokopha. Kulesi simo, umthamo we-fenofibrate ukhethwa udokotela ohamba yedwa, ebheka izimfanelo zomzimba wesiguli.
Endabeni yokusetshenziswa okuhlangene kwe-fenofibrate ne-cyclosporine, ukwehla okungaguquki komsebenzi wezinso kungenzeka. Ngakho-ke, lapho wenza ukwelashwa okunjalo, ukuqapha njalo isimo sesiguli kuyadingeka.
Osokhemisi bahlinzeka iziguli eziningana zesidakamizwa. Le mishanguzo inomehluko kusuka kwangempela, zombili ezindlekweni nokwakhekeni kwayo.
Banconyelwa ukusetshenziswa ezimweni lapho ukusetshenziswa kweLipantil ngasizathu singenakwenzeka.
Izinhlu zethuluzi yilezi:
- Nofibil;
- Ukuqothuka;
- I-Fenofibrate Canon;
- Lofat
- Tricor
- Grofibrat.
Ngaphambi kokufaka umuthi esikhundleni sawo, kufanele uvakashele udokotela futhi ubonisane naye ngalolu daba.
Imininingwane ekwelashweni kwe-atherosclerosis inikezwe kuvidiyo ekulesi sihloko.
