I-cholesterol ephezulu iba nemiphumela emibi njalo uma ukwelashwa kungaqali ngesikhathi. Uma into ingamanani ajwayelekile, kusiza kuphela.
Ukulingana kwezinhlobo ezimbili ze-cholesterol kusabalulekile: i-lipoproteins ephezulu yokuqina kwabantu kanye nama-lipoprotein aphansi. Noma zidingekile, umehluko wazo ulele ekutheni i-LDL ngenani elikhulayo ilimaza kakhulu umzimba wonke, ngoba ukugcwala ngokweqile ezindongeni zemithambo yegazi, kamuva kuvela ama-cholesterol plaip - ukuqala kwe-atherossteosis. I-HDL, noma isezingeni eliphakeme, iyasiza umzimba, ngoba ingavimbela izifo zenhliziyo futhi inciphise izinga le-cholesterol "embi".
Ngomqondo, konke kulula. Kepha ukuzijwayeza kufakazela ukuthi abantu abayibheki impilo yabo, futhi baphendukela ezikhungweni zezokwelapha uma kungenzeka ukuthi ukhubazeka ngokuphelele nobuhlungu obungapheliyo. Ngakho-ke ne-cholesterol, ngoba azikho izimpawu zokungasebenzi kahle.
Kwenzeka ukuthi ezimweni eziningi, ukuphula umthetho kutholakala kusenesikhathi. Ngemuva kwalokho ochwepheshe batusa izindlela eziningana zokwelapha, kufaka phakathi ukuthatha imithi ekhethekile. Phakathi kwazo kukhona ama-statins anjengeKrestor neLiprimar. Amanani ayakwazi ukunciphisa inani le-LDL ngesikhathi esifushane. Kepha, kaningi, ngenxa yezimo, iziguli zibuza lo mbuzo: yini engcono i-Liprimar noma i-Krestor? Ukuthola impendulo, kufanele utadishe ngokucophelela izakhiwo nezindlela zokusebenza kwale mishanguzo.
I-Crestor isidakamizwa sokuqala sase-rosuvastatin, umenzi - e-United Kingdom. Isakhi esiyinhloko i-calcium rosuvastatin, eyenziwe nge: crospovidone, calcium phosphate, magnesium stearate, lactose monohydrate. Isenzo saso sihlose ukwehlisa izinga lamazinga aphansi we-lipoprotein. Kuyaphawuleka ukuthi ayasebenza kakhulu, ngokungafani nezinye izidakamizwa ezifanayo. Ochwepheshe bavame ukunquma umuthi uma kunengozi enkulu yokuhlaselwa yisifo senhliziyo. Umuthi unomphumela:
- kwehlisa amazinga we-LDL;
- kunciphisa ukugxila kwe-triglycerides;
- kunciphisa ukugcwala kwama-lipoprotein aphansi kakhulu;
- ikhulula ukuvuvukala kwemithambo;
- kuthuthukisa amaprotheni e-C esebenzayo.
Imiphumela yokuhlolwa kwegazi ingathuthuka emavikini amabili nje, bese umphumela omkhulu ungatholakala ngenyanga. UKrestor uxhumana nezinye izidakamizwa kangcono kakhulu kunezinye izidakamizwa eqenjini.
Izinkinga zingavela ngokuxhumana nama-ejensi athinta amasosha omzimba, ama-antibiotic, izithiyo zokuvimbela inzalo, izithambisi zegazi. Ukuxhumana nalezi zidakamizwa kungadala ukungasebenzi kahle kwezinso nesibindi. Ngakho-ke, noma imuphi umuthi kufanele uvumelane nodokotela. Kubalulekile ukubika ngesikhathi ngazo zonke izimali ezithathwa yisiguli.
I-Liprimar isidakamizwa sokuqala sase-atorvastatin esenziwa eJalimane. Ngaphandle kokuthi izidakamizwa eziningi ezifanayo zithengiswa nale ngxenye, lesi sidakamizwa sithathwa njengekhwalithi ephezulu kakhulu.
Bona, ngokweqiniso, ashibhile, kodwa ukusebenza kwabo kuphindeke kaningi. Isakhi esiyinhloko i-atorvastatin, equkethe i-lactose monohydrate, i-crosscarmellose sodium, i-calcium carbonate, i-magnesium stearate, i-polysorbate 80, i-stearic emulsifier, i-hypromellose. Umuthi uthinta i-cholesterol ne-triglycerides. Ngokuvamile, kunomthelela onjalo emzimbeni:
- lowers inani cholesterol;
- kwehlisa cholesterol ye-LDL;
- kunciphisa ukugxilwa kwe-apoliprotein;
- lowers triglycerides;
- inyusa inani le-HDL.
Lesi sidakamizwa sisebenzisana kabi nezidakamizwa eziningi. Kuyinto engathandeki ikakhulukazi ukuyisebenzisa ndawonye nemithi elwa namagciwane, imishanguzo yokulwa nesikhunta, ngokumelene nomfutho wegazi ophakeme, ukuhluleka kwenhliziyo, kanye nezidakamizwa ezenza igazi libe mncane.
Endabeni yokuphuza umuthi ngaphandle kokutshela udokotela, kufanele uthintane nesikhungo sezokwelashwa ukuthola izeluleko.
I-Liprimar ithathwa hhayi kuphela uma kwenzeka cholesterol ephezulu. Kunezizathu eziningi zalokhu.
Akumele uphuze amaphilisi ngokwakho, ngoba naye une-contraindication.
Isidakamizwa sinconyelwa ukuthatha uma kuphakama i-cholesterol ephezulu kubantu abadala nasebasha, ukuvimbela ukuhlaselwa yisifo senhliziyo nokugwazwa kwe-ischemic, ukuvikela izinkinga zesifo senhliziyo.
Enye inkomba yobukhona besifo senhliziyo, i-hypertension, isifo sikashukela, isifo sokuqina kwemizwa.
Ngaphezu kwezinkomba, lesi sidakamizwa sine-contraindication yaso.
Kwezinye izimo, kufanele wenqabe ukuthatha umuthi. Thatha i-statin kufanele ibe ngemuva kwesivumelwano nodokotela, ngoba nguyena kuphela onqume ukuba khona kwezinkomba kanye nokuphikisana.
Umuthi uvinjelwe uma kwenzeka:
- i-pathologies yesibindi enzima;
- ukukhuphuka kwama-hepatic transaminases kuphakeme kathathu kunokujwayelekile;
- ukungabekezelelani komuntu ngamunye engxenyeni eyinhloko;
Kwezinye izimo, ukusetshenziswa kwalesi sidakamizwa kufanele kwenzeke ngokuqapha ngokweqile. Lapho kukhona izinto ezinjalo, udinga ukulungisa kancane umthamo, noma inkambo yokwelashwa.
Xhumana nochwepheshe. Ukuhlukumeza okuhlobene kufaka phakathi uphuzo oludakayo, isifo sikashukela, i-hypothyroidism, nezifo ezithathelanayo eziyingozi.
Isiphambano asinazinkomba ezingaphansi kanye nokuphikisana. Zonke ziyafana ngokuhlobene nesenzo esifanayo. Akuthathwa kuphela nge-cholesterol ephezulu, kodwa futhi ezimweni eziningi.
Izinkomba zifaka:
- I-cholesterol ephakeme kubantu abadala nentsha.
- Yehlisa ukuthuthukiswa kwe-atherosclerosis.
- Ukuvimbela ukuhlaselwa yisifo sohlangothi kanye nokushaya kwenhliziyo nesifo sikashukela.
- Ukuvimbela ubunzima benhliziyo.
Ubuye abe nemibango. Kwezinye izimo, ukwelashwa akunakwenzeka ngenxa yengozi yemiphumela. Ukuvimbela lokhu kungenzeki, udinga ukuxhumana nochwepheshe. Contraindication kufaka phakathi isifo sesibindi; ukwehluleka kwezinso; ukungabekezelelani komuntu ngamunye engxenyeni eyinhloko. Okunye futhi ukwephula umthetho yisikhathi sesiguli esifinyelela eminyakeni eyi-18.
Mayelana nezidakamizwa zokwehlisa i-cholesterol zichazwe kuvidiyo kule ndatshana.
