I-Atoris iyisidakamizwa esinomphumela ophansi we-lipid. Ngenxa yezici ezahlukahlukene, ngokwesibonelo, ukuphikisana, udokotela unquma i-Atoris analogues.
Phakathi kwazo, izichazamazwi ziyahlukaniswa, eziqukethe isakhi esifanayo esisebenzayo (i-Atorvastatin, Atomax), namalungiselelo we-analog aqukethe izinto ezihlukile ezisebenzayo, kepha onomphumela ofanayo wokwelapha (Rosart, Krestor). Cabanga ngokuningiliziwe ngezindawo ezidumile ze-Atoris.
Atoris - imininingwane ejwayelekile
I-ejenti ye-hypolipidemic Atoris (Atoris) iyingxenye yeqembu lama-statins elivimbela umsebenzi we-enzyme esibindini (HGM-CoA), elibhekele ukukhiqizwa kwe-cholesterol.
Umuthi ukhiqizwa kwifomu lethebhulethi emithanjeni ehlukene: 10 mg, 20 mg no-40 mg wengxenye esebenzayo ye-atorvastatin. Ithebhulethi elilodwa liqukethe inani elincane lababizi - i-povidone, i-sodium lauryl sulfate, i-magnesium stearate, i-lactose monohydrate, njll.
Indlela yokusebenza yesidakamizwa ihambisana nokucindezelwa kokuhlanganiswa kwe-cholesterol kanye nokwanda kabusha kwama-LDL receptors kwezicubu ezengeziwe nesibindi. Ngaphezu kwalokho, ama-receptors abopha izinhlayiya ze-LDL, azisuse egazini. Ngakho-ke, kukhona ukwehla kwe-cholesterol yegazi.
Udokotela ubeka u-Atoris ezimeni ezinjalo:
- iziguli ngaphandle kokuzwela ngokomqondo izifo zenhliziyo ukuze sinciphise ingozi yokuqunjelwa yi-myocardial infarction, stroke, angina pectoris kanye nesidingo se-myocardial revascularization;
- iziguli ezihlushwa isifo sikashukela esingeyona i-insulin (uhlobo 2) ngaphandle kwesifo esibuhlungu kakhulu somthambo wegazi ukuze sinciphise amathuba okuhlaselwa yisifo senhliziyo nokushaywa unhlangothi;
- iziguli ezinesifo senhliziyo esiveza umtholampilo ukuze sinciphise ubungozi bokufakelwa kwe-myocardial infalction, isifo esibulalayo nesingabulali, i-angina pectoris, isidingo sokuvuselelwa kabusha kwe-myocardial kanye nokulaliswa esibhedlela ngenxa yokwehluleka kwenhliziyo;
- njengokwengezwa kokudla okhethekile kwe-hypercholesterolemia eyisisekelo (yomndeni / okungeyona eyomndeni) futhi kuxutshwe (uhlobo IIa ne-IIb)
- njengokungezwa kokudla kwe-hypertriglyceridemia (uhlobo IV), dysbetalipoproteinemia (uhlobo III), kanye ne-homozygous Famer hypercholesterolemia;
- iziguli ezineminyaka engu-10 kuya kwe-17 ubudala ezinomlando womndeni we-pathology ye-inhliziyo yokuqala noma izinto ezingaphezu kwezimbili zokukhula kwazo.
I-Atoris inenani elincane le-contraindication. Phakathi kwazo, kuyadingeka ukugqamisa i-hypersensitivity ezingxenyeni zamathebhulethi, ukukhulelwa nesikhathi sokuphuza, ukungasebenzi kwesibindi kanye namazinga aphezulu we-transaminases.
Imiyalo yokusebenzisa umuthi
Imiyalo ithi ngaphambi kokuthatha lesi sidakamizwa, udinga ukushintshela ekudleni okukhethekile okuqukethe izinga lokwehliswa kwe-lipids. Ukudla kufanele kubhekwe ngesikhathi sokuphathwa kwe-Atoris.
Imithamo nesikhathi ubude besifundo sinqunywa ngudokotela ohambelayo.
Umthamo owamukelwa nsuku zonke ekuqaleni kwekhosi yi-10 mg. Uma ngemuva kwamaviki amabili umphumela ofanele wokwelapha ungenzeki, uchwepheshe uyandisa kancane kancane le dosi liye kuma-80 mg ngosuku. Izingane nentsha, njengomthetho, ekuqaleni inqunywe i-10 mg ngosuku.
Kuyaqapheleka ukuthi umuthi ubekwe ngokuqapha ezigulini ezine-pathologies yesibindi. Uma umsebenzi wama-enzyme wesibindi wanda okuphindwe kathathu, ukusetshenziswa kwamacwecwe kuzodingeka kukhanseliwe.
I-Atoris isidakamizwa eseqophelweni eliphezulu esingabangeli ukusabela okungekuhle. Ngezikhathi ezithile, ukwephula imithetho yokuphuza umuthi, kungaveza imiphumela emibi:
- Ukuphazamiseka kwengqondo kwe-dyspeptic, ubuhlungu besisu, ukulahleka kwesifiso, ukuphuma kwezilonda kwe-bile, i-pancreatitis kanye ne-hepatitis.
- I-Myopathy, Ubuhlungu nobuthakathaka bemisipha, i-myositis kanye namaqhubu.
- Isiyezi, ukindlebe kanye nomuzwa obukekayo emilenzeni, ikhanda, ukuthuthukiswa kweheropathy ye-peripheral.
- Ukuba khona kwe-hyper- noma i-hypoglycemia, amazinga aphezulu we-enzyme yesibindi ne-CPK egazini.
- I-edema ye-Angioneurotic, ukulahleka kwezinwele, ukuqubuka kwesikhumba nokulunywa.
Imiphumela emibi ingafaka ubuhlungu bokuqina, ukuncipha kwe-potency kanye ne-asthenia.
Izithonjana ze-Atoris
Uma kukhona ama-contraindication noma ukusabela okuphikisayo esigulini, udokotela ubhekene nomsebenzi wokukhetha indawo enhle ye-Atoris.
Ngemininingwane, i-Atoris (amaphilisi ayi-10 mg 30) intengo ephakathi ingama-ruble angama-330.
Emakethe yezokwelapha yaseRussia, kunamagama amaningi wokuvumelanisa izidakamizwa ahlukile ekwakhiweni kwezingxenye ezengeziwe nezindleko:
- I-Atorvastatin isidakamizwa esifuywayo neshibhile. Iqukethe uhlu olufanayo lwezinkomba kanye ne-contraindication. Umthamo wokuqala ngu-10 mg ngosuku. Izindleko ezijwayelekile (10 mg, amaphilisi angama-30) ngama-ruble ayi-126.
- I-Atomax yisidakamizwa esenziwa yinkampani yezokwelapha yaseNdiya. Ikhiqizwa ngomthamo we-10 mg no-20 mg, ngakho-ke ayilungeleki kakhulu ezigulini ezinezindlela ezinzima ze-atherosulinosis nezifo zamasipha.
- I-Ator iyi-analogue eshibhile ye-Atoris. Ngokusho kokubuyekezwa okuningi nezifundo zemitholampilo, umuthi wehlisela ngempela ubungozi bokuthola isifo sokuqina kwesifo sikashukela kanye ne-inhliziyo pathologies.
- I-Liprimar isidakamizwa esinciphisa i-lipid senziwa eJalimane. Ithuluzi lehlisa ngempumelelo i-cholesterol. Phakathi kokushiyeka, izindleko eziphakeme kufanele ziqokonyiswe - ama-ruble angama-695 (10 mg, amaphilisi angama-30).
Njenge-analogue, kusetshenziswa iTorvard - isidakamizwa esikhiqizwa yinkampani yaseSlovenia iZentiva. Imithamo yomenzeli wokwehlisa i-lipid ayihlukile kune-Atoris.
Intengo ejwayelekile yokufaka (10 mg, amaphilisi angama-30) ngama-ruble angama-270.
Izidakamizwa ngesinye isithako esisebenzayo
Iqembu lama-statins lihlanganisa inani elikhulu lezidakamizwa.
Kuyaqapheleka ukuthi i-Atoris kanye nezimpawu zomqondo wayo kuhlobene nezidakamizwa zesizukulwane sesithathu, ezokwehlisa ngempumelelo i-cholesterol futhi empeleni azibangeli miphumela emibi.
Kukhona uhla lonke lwezidakamizwa lapho i-compact esebenzayo ihluka khona efektri e-Atoris.
Imithi efanayo ye-cholesterol:
- I-Rosart isidakamizwa esiqukethe i-rosuvastatin. Kuyinto evimbelayo yokunciphisa kabusha i-HMG CoA. Izindleko (5 mg, amaphilisi angama-30) zilingana ama-ruble angama-430.
- IVasilip ingumuthi oqukethe isithako esisebenzayo yi-simvastatin. Umuthi unciphisa ukugcwala okujwayelekile nokwanda kwe-LDL. Intengo yesidakamizwa iphansi - ama-ruble ayi-140 (10 mg, amaphilisi ayi-14).
- I-Mertenil yi-ejenti ye-hypolipidemic enengxenye esebenzayo rosuvastatin. Izinkomba eziphambili ukwelashwa kwe-hypercholesterolemia kanye nokuvinjezelwa kwezifo zenhliziyo. Izindleko ezimaphakathi zomuthi (10 mg, amaphilisi angama-30) ama-ruble angama-545.
- I-Choledol ingumuthi owenziwa yinkampani yemithi yaseBelarus. Kuyinto yokumiswa koketshezi okusetshenziselwa ukwenza i-lipid metabolism ibe yijwayelekile, ukuvimbela ukuhlaselwa isifo sohlangothi nokushaya kwenhliziyo. Izindleko ngama-ruble angama-750.
- I-Kuaymiy ithatha indawo yezitshalo e-Atoris. Izithasiselo ziholela ekwehleni kwesifiso sokudla, ukuzinza kwe-lipid metabolism, ukuqedwa kobuthi kanye noketshezi oluningi. Izindleko zesengezo sokudla zivela ku-1700 kuya ku-1800 ruble.
I-atherossteosis ayikwazi ukwelashwa ngamakhambi abantu kuphela, ngakho-ke kubalulekile ukuthatha imishanguzo ephumelelayo. Ngakho-ke, i-Atoris inezinhlobo eziningi zama-20 mg, inani lazo lihluke kakhulu.
Ungazithatha kanjani izazi ze-statins kuvidiyo ekulesi sihloko.
