I-Urinalysis yokuhlushwa kwe-alpha-amylase (diastase) kuyindlela ebaluleke kakhulu yokuxilonga yokuqinisekisa ukutholakala kwe-pancreatitis.
Imvelo yokuchama kokuchama kubantu abadala abane-pancreatitis isebangeni ukusuka kuma-10 kuya ku-128 amayunithi / ilitha. Ezinqubweni ze-pathological, izifo, ezihambisana nokushintshwa kokuhlushwa kwama-enzymes we-pancreatic, ukugcotshwa kwe-diastase kukhuphuka kaningana.
Yini i-alpha amylase (diastase)?
I-Diastase yiprotheni eyenziwe nge-pancreas (ama-pancreas) futhi enamakhono e-enzymatic. Ngaphezu kwamanyikwe, amangqamuzana ezinhlayiya ze-salivary nawo akhiqiza i-diastasis.
I-prerogative main ye-diastase ukufakwa kwe-biodegradation of polysaccharides (isb. Isitashi) ku-monosaccharides 
(ushukela) ukumunca umzimba. Izinga le-diastase ekudleni lomchamo liyinkomba ebalulekile yokuxilongwa kwe-pancreatic pathologies.
I-pancreatitis ye-acute iholela ekwandeni kwe-diastase. I-psychology eqinile, ehambisana nomonakalo kumaseli we-pancreatic, ngenxa yokukhishwa kwenombolo enkulu yama-enzyme e-pancreatic egazini. Njengoba i-diastasis incane, iyakwazi ukungena kusihlungi se-renal. Ngakho-ke, i-diastasis ye-urinary ku-pancreatitis iyanda.
Ukwanda kokuhlushwa kwaso kuqaphelelwa kumacala alandelayo:
- Ukwanda kwe-pancreatitis engapheli, ngokubuyela kwesifo, ukwanda kwe-alpha-amylase egazini futhi, ngenxa yalokho, kumchamo kuvame ukubonwa;
- Umdlavuza we-pancreatic yisifo esibi i-oncological esine-prognosis engathandeki; ezimweni eziningi, lesi sifo sithinta isilinganiso segazi nokuchama komchamo;
- I-pancreatic necrosis yisimo esibuhlungu sokuvuselela umzimba, esivame ukuholela ekufeni;
- Ukuphazamiseka kwemetabolic, kufaka phakathi isifo sikashukela;
- I-pathology yokuhlinzwa esiswini esibuhlungu kakhulu: ukuvuvukala kwesithasiselo, isimila senyongo, i-gynecological (kufaka phakathi ukukhulelwa kwe-tubal) noma i-urological pathology;
- Ukudakwa kotshwala - iziphuzo ezinamandla ezidakayo zinomphumela we-pancreotoxic futhi kunomthelela olimazayo kwezicubu zezitho;
- Ukulimala kwe-pancreatic;
Ngaphezu kwalokho, ukuba khona kwezifo eziwubhubhane esigulini kuholela ekwandeni kokuhlushwa kwe-diastases.
Ukuxilongwa kwe-pancreatic pathology
I-Urinalysis ye-pancreatitis, noma izinsolo zayo, kufanele yenziwe ngokushesha okukhulu ukuze kugwenywe ukuguqukela esigabeni se-necrotic.
Ukuhlolwa kwe-urinalysis kwe-pancreatitis kuyindlela yokuxilonga eyinhloko.
Kepha ukuthola ukuxilongwa okuyikho, kubalulekile ukwenza ezinye izifundo.
Ngale njongo, kwenziwa lezi zifundo ezilandelayo:
- Amaprotheni. Kubaluleke kakhulu ukuthola iprotheni kumchamo nge-pancreatitis ukuze ukhiphe i-nephrotic syndrome. Njengoba i-diastase ingaba nomthelela ekuqineni kwezingxenye zomchamo, umchamo obomvu nge-pancreatitis akuyona into eyivelakancane. Imvamisa, umbala omnyama womchamo udukisa hhayi kuphela isiguli, kodwa futhi nodokotela onolwazi.
- Ukuhlolwa kwegazi komtholampilo kuzonquma izinga lokuwa kwe-hemoglobin namangqamuzana abomvu egazi (erythrocyte) ngenxa yokuphuma kwegazi emithanjeni echithiwe yesitho esigulayo. Ngaphezu kwalokho, isibalo se-leukocytes ne-ESR ku-pancreatitis siyanda, okubonisa ubukhona bokuvuvukala. Futhi, ngokuhlolwa kwegazi okujwayelekile, umuntu angahlulela isilinganiso sezakhi ezifanayo zento kanye ne-plasma.
- Ukuhlolwa kwegazi okune-biochemical kukuvumela ukuthi uthole ukwanda kokuxwalwa kwe-elastase, trypsin namanye ama-enzymes e-pancreatic, hypoglycemia, kanye nokwehla kwezinga lamaprotheni egazi. Kwesinye isikhathi amazinga we-bilirubin enyuka ezigulini, okubonisa ngokungaqondile i-pathology yamanyikwe. Ukukhula kwale pigment nakho kuvame ukuholela ekutholakaleni okungalungile kwe-cholecystitis noma i-hepatitis.
- Ukuhlaziywa kwezindunduma zokuba khona kwama-lipids angalungisiwe, imicu, imicu yamaprotheni. Izinguquko ezinduneni zihlanganiswa nomsebenzi we-enzymatic we-pancreatic okhubazekile kanye nokubandakanyeka kwesibindi kanye ne-gall bladder. Kukhona indawo yokubamba.
Izindlela zesibili zokuxilongwa kwe-pathology zifaka i-MRI, ukuhlolwa kwe-immunological nokutholwa kwama-antibodies ahlukahlukene, ukuxilongwa kwe-CT, i-ultrasound.
I-Etiology yokuhlushwa kwe-diastase ekhulayo ku-pancreatic pathology
Uma kukhona izinsolo zokuqalwa kokukhula kwama-pathologies kumanyikwe, okokuqala, uchwepheshe uthumela isiguli ukuthi sihlaziye umchamo.
Imvamisa, ama-enzyme akhiwa engxenyeni ye-exocrine yesitho senziwa kumthambo we-duodenal kuphela. Ku-pathology, ukusebenza kwe-enzyme, kufaka phakathi ama-diastases, kuqala kumacucu we-pancreatic. Ngakho-ke, izinto ezisebenzayo ziqala "ukuzicwilisa" isitho. Ama-pancreatocytes ayabhujiswa - amaprotheni asebenzayo angena ekusakazweni kwe-systemic.
Kulokhu, indlela efundisayo kakhulu ukukala ukugxilwa kwama-enzyme egazini nomchamo, okungukuthi ama-diastases. Ngale "ukuhlinzwa", izinga le-diastase lenyuka ngamakhulu amahlandla.
Ucwaningo lomtholampilo olujwayelekile lomchamo luyenziwa, ngoba le ndlela itholakala kalula futhi kulula ukuyenza, nge-pancreatitis ekuhlaziyeni komchamo, kukhuphuka okuhambelana namagugu we-diastase yegazi. Ukuthola izifundo ezinjengale akunzima, kepha kufanele kukhunjulwe ukuthi ama-laboratories ahlukene anika amanani ahlukile wereferensi.
I-diastase ye-diastase nayo ingaba ne-iatrogenic etiology, okungukuthi, ngenxa yokudla izidakamizwa ezithile.
Izinto ezinjalo zifaka:
- Imithi elwa namagciwane ochungechunge lwe-tetracycline inegalelo ekwandeni kwama-enzymes egazini nokuvela komxhumo womchamo onemibala emnyama, ongathinta ukuxilongwa okungalungile. Udokotela ubophekile ukuxwayisa iziguli ezilashelwa izifo ezithathelwanayo.
- I-Alpha-adrenergic blockers (i-adrenaline, i-norepinephrine) isetshenziswa ekwelapheni ukushaqeka kwe-etiologies ehlukahlukene. Njengoba leli qembu lezidakamizwa lingelikhulu kulo lonke iqembu le-alpha-blockers, ukwanda kokuhluka ngokuphathwa kwabo kuyizwe lesikhashana.
- Ama-Cytostatics nezinye izidakamizwa ezisetshenziselwa ukwelapha iziguli ezinomdlavuza. Leli qembu lezidakamizwa yizinto ze-chemotherapeutic futhi linemiphumela emibi eminingi, kufaka phakathi umphumela omubi kumaseli we-pancreatic kanye nejusi le-pancreatic.
Ngaphezu kwalokho, ama-NSAIDs asetshenzisiwe. Leli qembu lezidakamizwa laziwa yiwo wonke umuntu - le yimithi engeyona eye-narcotic noma izidakamizwa ezingezona ze-antiidal.
Lokhu kufaka phakathi i-Analgin, Nimesil, Diclofenac, Ibuprofen nabanye abaningi. Cishe wonke umuntu omdala nengane baphuza inani elikhulu lale mishanguzo empilweni yabo futhi ungacabangi ngemiphumela yabo emibi engaba khona. Kusukela kumthelela omubi ku-mucosa wesibeletho, kuphela ngokuvuvukala kwe-necrotic kumaseli wamanyikwe.
Imithetho yokuqoqa ukuhlaziywa kwe-diastase
Umthetho wokuqala wokucwaninga ophumelelayo yisikhathi. Uma kunobuhlungu bebhande, uphawu lweVoskresensky noma ezinye izimpawu zokuphawuleka, isiguli sidinga ukubona udokotela ngokuphuthumayo. Udokotela onekhono ngokusola izinqubo ezinamandla, into yokuqala ukuthumela isiguli sakho ukuthi sihlolwe umchamo we-encyme ye-pancreatic.
Isitsha sokuqoqa kufanele singabinayo insimbi nesembozo esifanelekile. Ukuhlaziywa, umsizi welebhu udinga isamba esincane soketshezi lomzimba. Kubalulekile ukuqala isifundo masisha ngemuva kokuthola isampula - ngoba ama-enzyme akuzona izinto ezizinzile. Futhi, ukuqinisekisa ubuqiniso bemininingwane, i-serum yegazi ihlolisiswa i-enzyme. Kungcono ukuhlolwa ekuseni kakhulu.
Isazi sevidiyo esikulesi sihloko sizosho mayelana nokuhlaziywa komchamo we-diastasis.
