I-Lipoic acid yinto engadalwa ngokuhlanganiswa kanye nangezimo zemvelo.
Kunamagama ahlukahlukene ento enjalo, afaka:
- thiocticꓼ
- alpha lipoicꓼ
- uvithamini N.
Ukusetshenziswa okusebenzayo kwe-lipoic acid namuhla kungenxa yomthelela omuhle emzimbeni womuntu, ukwakheka okuhlukile kwezakhi zawo. Ukulungiswa kwe-Lipoic acid kuvame ukusetshenziswa emithini yesimanje njengendlela yokunciphisa isisindo. Ngaphezu kwalokho, amaphilisi anjalo (kufaka phakathi uhlobo lwezithasiselo zokudla) ngokuvamile athathwa abasubathi.
Ungayithatha kanjani i-lipoic acid futhi yikuphi ukudla okuqukethe i-lipoic acid?
Izici zesakhiwo
Ngaphandle kokuthi i-Vitamin n (i-lipoic acid) ingakhiqizwa ngokwemvelo ngumuntu, ngokuvamile leli nani alanele enkambweni evamile yezinqubo eziningi zezitho zangaphakathi nezinhlelo.
Kungakho, ukugcwalisa ukusilela, abantu abaningi basebenzisa izidakamizwa nge-lipoic acid.
Le nkinga iba ofanele ikakhulukazi phambi kwezifo ezahlukahlukene zesibindi (ikakhulukazi i-hepatitis).
Ukuze umzimba uthole inani ledatha efana ne-lipoic acid, kuyadingeka:
- Sebenzisa amaqembu womkhiqizo athile acebile kule ngxenye.
- Thatha imishanguzo ususelwa kuyo.
I-Lipoic acid (i-Vitamin n) inezakhiwo ze-antioxidant, ezinomphumela onenzuzo ekubophweni kwama-free-hlobo radicals. Ngaphezu kwalokho, enye yezinzuzo ezingenakuphikwa yikhono lokwenza amazinga e-glucose abe ngokwejwayelekile kanye nekhono lokukhulisa iphesenti le-glycogen esibindini.
Amandla amakhulu nezimpawu zalo msebenzi yilezi:
- isiza ukunciphisa imiphumela yezinto ezinobuthi ezinjengezinsimbi ezisindayo nosawoti,
- uphatha imiphumela ye-hepatoprotective kanye detoxization,
- umphumela omuhle empilweni yesibindi,
- ulwa ngenkuthalo nama-radical hlobo wamahhala, lesi senzo sanda ngokukhethekile ngamavithamini E no-C,
- isiza ukunciphisa i-lipids ne-cholesterol embi,
- I-glucose ejwayelekile
- kuthinta kahle ukusebenza kohlelo lwezinzwa,
- uphatha imisebenzi yokuvikela ephathelene nemiphumela emibi yemisebe ye-ultraviolet,
- Iqhaza elisebenzayo ekuphatheni indlala yegilo,
- inyusa inani lamaprotheni akhiqizwayo futhi yehlise izinga lamafutha acid,
- inomphumela we-choleretic,
- ingaba nemiphumela elwa nama-antispasmodic,
- ivumela kahle ukwehla kwamandla kweprotheni e-glycolised,
- kunciphisa ingozi yokufa yindlala komoya-mpilo wamangqamuzana omzimba.
I-Lipoic acid yifomu lokukhishwa elingafakwa emakethe yamakhemikhali, ezinhlotsheni ezimbili - kumathebhulethi noma emaphaketheni (kuze kufike ku-600 mg wento esebenzayo), izixazululo kuma-ampoules wokujova noma ukungena kwe-intravenous.
Yiziphi izinqubo zevithamini ezisetshenziselwa ukwelapha i-Vitamin N?
Umuthi wanamuhla usebenzisa umuthi ngentshiseko ekulweni nezifo ezahlukahlukene zesibindi.
Amathebulethi e-Lipoic acid athinta kahle ukusebenza kwejwayelekile kwesitho sangaphakathi, futhi abe nemisebenzi ye-hepatoprotective, hypocholesterolemic, hypolipidemic kanye ne-hypoglycemic kumaseli ayo.
Ukusetshenziswa kwesidakamizwa kukhuthaza ukuqothulwa okusheshayo kwezinto ezinobuthi ezinhlobonhlobo.
Ngaphezu kwalokho, umuthi ungasetshenziswa ukuqeda lezi zifo ezilandelayo:
- Ngesifo senhliziyo yesifo sethambo.
- Kwi-oncology.
- Ukusebenza kahle ngaphakathi kanye nokukhubazeka kwesibindi.
- Njengoba kungenye yezakhi zokwelashwa kwezidakamizwa sikashukela.
- Ngokuthuthukisa umfutho wegazi ophakeme kanye nomfutho wegazi ophakeme.
- Ukutheleleka nokudakwa komzimba.
- Ngokuthuthukiswa kwe-polyneuropathy yesifo sikashukela noma yotshwala.
- Uma kunokuphazamiseka ekuzwelweni kwemikhawulo engezansi.
- Ukuvuselela ubuchopho.
- Njengesinyathelo sokuvimbela ukwenza ngcono ukusebenza kwe-yegilo yegilo.
- Ukugcina ama-acuity ezibukwayo.
Imiyalo ye-Lipoic acid yokusetshenziswa ichaza zonke izinhlobo zezinkomba zokusetshenziswa kwento, ukwakheka nezakhiwo zomuthi, imiphumela emibi nokuphikisana.
Kumele kuqashelwe ukuthi i-lipoic acid (izinkomba ezisetshenziswayo) isiza ukunciphisa inani le-ammonia egazini, okuthinta kahle ukungathathi hlangothi kwezimpawu ze-encephalopathy. Ngaphezu kwalokho, ezinsukwini ezimbalwa ngemuva kokuqala kwemithi, kuyehla ukuncipha kwezimpawu zomzimba ezigulini ezine-hyperammonemia ne-portocaval anastomosis. Umuthi futhi usetshenziswa ngenkuthalo ekwelashweni okuyinkimbinkimbi kwe-cholecystitis kanye ne-hepatitis yezinhlobo eziyingozi ikakhulukazi. Ekwelapheni i-cholecystitis, umuthi usetshenziswa zombili ngaphambi kokuhlinzwa nangemva kwawo. Ngenxa yomthelela we-lipoic acid, ukululama okusheshayo kwenzeka ngenxa yokulawulwa komsebenzi wezinto ezikhethekile nezakhi eziku-serum yegazi, kanye nokwenyuka kwesibalo senkontileka ye-gallbladder.
Umthamo womkhiqizo wezokwelapha ukhethwa ngawodwana, ngokuya ngesifo kanye nobucayi baso. Uchwepheshe wezokwelapha, ngokususelwa kulezi zinto, wenza ukubalwa kwamthamo okudingekayo. Njengomthetho, umthamo wansuku zonke Umuthi onjenge
I-Lipoic acid intengo ephakathi (izindleko) emakethe yamakhemikhali cishe ama-ruble angama-350. Ungasebenzisa futhi izifinyezo zayo zesabelomali ngokwengeziwe zokukhiqiza zaseRussia noma amathuluzi ahlanganisiwe akhethekile afaka le ngxenye (i-feretab, ngokwesibonelo).
Ama-analogues we-Lipoic acid anomthelela ofanayo futhi angahluka ngezindleko, umthamo noma inkampani yokukhiqiza.
Kwenzeka kanjani ukwenzeka kwesisindo lapho usebenzisa umuthi?
I-Lipoic acid imvamisa ithathwa ngabesifazane ukukhipha isisindo ngokweqile. Kufakazelwe ngokwesayensi ukuthi ngemuva kwamashumi amathathu, ukuzikhiqiza komzimba kwale nto kuncishiswa kakhulu, okuba ngesinye sezimbangela zokukhuluphala. Kungakho amalungiselelo asetafuleni asetshenziselwa ukuntuleka kwevithamini N okuholela.
Ngenxa yokusetshenziswa kwe-lipoic acid, i-metabolism nezinqubo eziningi ze-metabolic ziyasheshiswa, futhi ubuthi buyaqedwa. Ngaphezu kwalokho, kunokuvuselelwa okujwayelekile komzimba, isimo sesikhumba, izinwele nezinzipho siyathuthuka. Umuthi usebenza izinqubo ze-metabolic, ngaleyo ndlela ukwandisa ukusetshenziswa kwamandla, okuholela ekunciphiseni kancane kancane kwesisindo. Ngaphezu kwalokho, ngemuva kokuthatha lesi sidakamizwa, kubanjwa ukudambisa indlala, okukuvumela ukuthi udle ukudla okuncane.
Kumele kuqashelwe ukuthi ingxenye ngokwayo ayinayo imiphumela evuthayo yokushisa amafutha, futhi ngenxa yalokho umuntu akufanele alindele isimangaliso ekusebenziseni kwayo. Kuhlanganiswe kuphela nendlela yokuphila esebenzayo kanye nokudla okulinganiselayo lapho ungathola khona umphumela oyifunayo futhi wehlise isisindo (ividiyo).
Izazi zezempilo zivame ukuncoma ukusebenzisa i-lipoic acid enento efana ne-levocarnitine (ummeleli wama-amino acid). Ukusetshenziswa kwabo okuhlangene kukuvumela ukuthi uthuthukise umthelela womunye nomunye, ukuze inqubo yokunciphisa isisindo isheshe. I-Levocartinin igqugquzela ukusetshenziswa kwezimali zamandla avela emafutheni omzimba akhona, futhi i-lipoic acid isekela inani lamandla adingekayo usuku lonke.
Khetha kahle umthamo oludingekayo unguchwepheshe wezokwelapha kuphela. Njengomthetho, inani labo liyahluka kusuka kumakhulu amabili kuya kwamakhulu ayisithupha wamamayela wesakhi esisebenzayo ngosuku.
Kubalulekile ukuthi ungadluli imithamo yomuthi enconyiwe, njengoba kuqubuka imibango ehlukahlukene nokusabela okubi, ukuphazamiseka ekusebenzeni okujwayelekile kwezitho nezinhlelo zomzimba kungenzeka.
Inhloso yokusetshenziswa kwalesi sidakamizwa ezondlameni zezemidlalo?
ILipoic acid nayo yathola ukusetshenziswa kwayo ekwakheni umzimba.
Ukuzivocavoca umzimba kuyimpawu eyimfanelo yawo wonke umuntu, futhi ukuthatha isidakamizwa kusheshisa kakhulu izinqubo ze-metabolic kanye ne-metabolism, kunomthelela omuhle ohlelweni lokwakha izicubu zomzimba.
Ngesikhathi sokuzivocavoca ngokomzimba ku-mellitus yesifo sikashukela, umzimba womuntu usebenzisa amandla amaningi kunokuthola, ngakhoke wenza kube nokuntuleka kwawo ngenxa yolwelwesi etholakalayo. Kuyi-deposits enamafutha kangangokuba i-thioctic acid ivele iguquke ngesikhathi sokuzivocavoca.
Ngaphezu kwalokho, ukuqeqeshwa njalo ezindaweni zokuzivocavoca kuholela ekwakhiweni okukhulu kwama-radical hlobo lohlobo, okuthinta kabi ukwakheka kwamaseli womzimba. Usebenzisa i-lipoic acid, le nqubo ingagwenywa.
Umphumela onenzuzo wesidakamizwa ngesikhathi semidlalo uqondiswa:
- ukunciphisa imiphumela emibi yama-radicals wamahhala kumaseli womzimba
- ukulawulwa kwesilinganiso esijwayelekile sama-lipids namaprotheniꓼ
- ukwanda kwesisindo semisipha
- amandla adingekayo nokululama okusheshayo ngemuva kwemidlalo esebenzayo active
- ukugcina amazinga e-glycogen ngenani elidingekayo
- ukwanda kwe-glucose flux kumaseli nezicubu.
Into esebenzayo iyisakhi esibaluleke kakhulu sokwakha umzimba futhi ifakwe ezintweni eziningi zokudla kwezemidlalo.
Imiyalo yokusebenzisa umuthi
Ngaphandle kwenombolo enkulu yezinzuzo ezivela ekusebenziseni, kukhona izimo lapho ukusetshenziswa kwalo muthi kwenqatshelwe.
Ukuzilawula kwe-lipoic acid akunconywa.
Ngaphambi kokusebenzisa umuthi, bonana nochwepheshe wezokwelapha.
Okokuqala, i-lipoic acid contraindication ifaka okulandelayo:
- Sebenzisa ingane engaphansi kweminyaka eyisithupha.
- Ngesikhathi sokukhulelwa nokuncelisa okwalandela.
- Uma kwenzeka ukungabekezelelani okuthile kwento leyo noma ukwanda kwezinga lokuzwela kuyo.
- Uma kukhona ukungabekezelelani kwe-lactose noma inani elanele le-lactose.
- Ngokuthuthukiswa kwe-glucose-galactose malabsorption.
Ukuphuza okungafanele noma ukukhetha imithamo (ikakhulukazi inani elikhulu layo) kungaholela ekubonakalisweni kokungaphenduki okungekuhle nokuphikisayo kusuka ezithweni zangaphakathi nezinhlelo. I-drug overdose ingabonakala ngesimo sokucanuzelelwa kwenhliziyo kanye nokuhlanza, ikhanda elibuhlungu, i-hypoglycemia (ukwehla okukhulu kweglucose yegazi), nokubopha kwegazi.
Imiphumela emiphumela emqoka ifaka okulandelayo:
- ukushaya kwenhliziyo
- isicanucanu, kwesinye isikhathi esihambisana nokuhlanza,
- Izinkinga zesitulo, isifo sohudo,
- isikhumba esiswini
- ukukhuphuka kokujuluka
- ukungaboni kahle
- isiyezi nobuthakathaka obujwayelekile, okwenzeka ngokumelene nesizinda sokuthuthuka kwe-hypoglycemia.
Ngaphezu kwalokho, ukungezwani komzimba kungavela ngendlela yokulunywa kwesikhumba noma ukuqubuka okuhlukahlukene, ubomvu.
Yikuphi ukudla okuqukethe i-Vitamin N?
Ukunxenxa ukuswela kwe-alpha lipoic acid, ungasebenzisa amakhambi akhethekile noma izengezo ezisebenza ngokusebenza.
Kodwa-ke, iningi lazo linezibonakaliso ezingezinhle ezahlukahlukene noma imiphumela emibi.
Kungakho, okokuqala, kunconyelwa ukuthi kubuyekezwe kabusha indlela yokudla ejwayelekile, ukuyicebisa ngemikhiqizo enenani elikhulu lale nto ekwakhiweni kwayo.
IVitamin N iyatholakala kulokhu kudla okulandelayo:
- Isibindi, izinso, noma inhliziyo yenkukhu.
- I-Greens (i-arugula, iparsley, i-basil), isipinashi ne-broccoli.
- Inyama ebomvu enamafutha amancane (ikakhulukazi i-veal).
- Irayisi ebilisiwe
- Imifino emisha efana nopelepele wensimbi, izaqathi, u-anyanisi, izinhlobo ezihlukile zeklabishi, uphizi.
- Amaqanda enkukhu
- Ukudla kwamagundane.
Ukudla okwenziwe kahle kuzoba nomthelela omuhle enhlalakahleni yomuntu, kugcwalise umzimba ngamavithamini kanye namaminerali adingekayo, futhi kuqinise namasosha omzimba ngaphandle kwemithi ehlukahlukene.
Izinzuzo ze-lipoic acid zabanesifo sikashukela zichazwe kuvidiyo kule ndatshana.