Odokotela abaningi batusa ukuthi iziguli zabo zithathe amaphilisi e-Dibicor. Lo muthi unokwakheka kwendawo yonke futhi ulusizo kakhulu ekwelapheni isifo sikashukela. Umuthi unemisebenzi evikela ulwelwesi lwento esebenzayo esemqoka, ngemuva kokusetshenziswa kwayo, intuthuko kuzo zonke izinqubo ze-metabolic emzimbeni iyaphawulwa.
Isithako esikhulu esisebenzayo somuthi yi-taurine, sinomthelela ekucebiseni umzimba ngama-amino acid adingekayo, i-histamine, i-cysteine ne-methionine.
Ngaphandle kokuthi lo muthi unesilinganiso esanele sezinto ezizuzisayo futhi unomphumela omuhle emzimbeni womuntu, kusadingeka ukuqala ukwelashwa ngawo, kuyadingeka kuphela emva kokubonisana nodokotela okokuqala. Kuyadingeka ukwenza uhlolo oluphelele lwesiguli, futhi selususelwe kwidatha etholakele, baphethe ngokuthi yiziphi izidakamizwa zohlobo lwe-2 yesifo sikashukela ezifanele ecaleni elithile, lolu hlu lukhulu impela.
Izindleko ze-Dibikor zentando yeningi impela, intengo yayo iyahlukahluka kubanga ukusuka kuma-ruble angama-290 kuya kwangama-500 ngephakeji ngalinye. Izindleko zomuthi zixhomeke kumthamo wekhompiyutha enkulu esebenza nasesifundeni lapho kuthengiswa khona umuthi eRussia.
Kubalulekile ukukhumbula ukuthi i-Dibicor analogues inesilinganiso esanele sezakhamzimba.
Ukuze uqonde ngokunembile okusho ukuthatha i-analog noma i-Dibicor, ukwakheka kwanoma yimuphi umuthi kudinga ukwaziwa kahle.
Ukwakheka komuthi, uhlobo lokukhululwa, ukugcinwa kanye nemibandela yokuthengisa
Ikhuluma ngokuthe ngqo nge-taurine, khona-ke kwithebhulethi elilodwa kuqukethe ama-milligram angamakhulu amabili namashumi amahlanu noma amahlanu.
Sebenzisa umuthi ngokuqinile njengoba uyalelwe udokotela. Udinga ukukhumbula ukuthi udinga ukuyithenga emakhemisi ezikhethekile, ngoba umuthi omuhle kakhulu lo.
I-Dibikor, imiyalo esetshenziswayo equkethe imininingwane ephelele yokuthi ungaphuza kanjani amaphilisi nokuthi yiziphi izimo lapho kudingeka ukwenza, isebenza kahle ekwelapheni isifo sikashukela kanye nasekuxilongeni okuhambisana nokwakhiwa kwezifo zenhliziyo. Ngendlela, uma sikhuluma ngokuthe ngqo ngesifo sikashukela, khona-ke lo muthi usiza nganoma yiluphi uhlobo lwalesi sifo.
Kepha ngaphezu kwakho konke ukuxilongwa okungenhla, odokotela batusa ukusebenzisa umuthi ubuthi esigulini ngezidakamizwa ezifaka into engeyohlu lwama-glycosides enhliziyo.
Odokotela abaningi batusa i-Dibicor ngoba kusiza ukuguqula izinqubo ze-metabolic emzimbeni. Ngamanye amagama, lo muthi unomphumela oyinkimbinkimbi esigulini. Ngemuva kokusetshenziswa kwayo, intuthuko ezinhlelweni eziningi ezibalulekile iyaphawulwa.
Isidakamizwa i-Dibikor, ngaphezu kwento esemqoka esebenzayo ekwakhiweni kwayo iqukethe izingxube ezenza umsebenzi osizayo.
Lezi zingxenye yilezi:
- isitashi;
- i-gelatin, inqwaba yabanye ababukeli;
- i-microcrystalline cellulose.
Kunikezwa incwadi kadokotela. Impilo yeshelf iyiminyaka emithathu kusukela ngosuku lokwenziwa.
I-Pharmacodynamics ne-pharmacokinetics yesidakamizwa
Mayelana nokuthi yini imihlomulo yomuthi i-Dibikor esivele ishiwo ngenhla, kepha ngasiphi isimo esingaba nemiphumela emibi, sidinga ukukhuluma kabanzi.
Yini imihlomulo yaleli thuluzi? Le nto yokwelapha ithuthukisa ukushintshaniswa kwe-ion ye-calcium ne-potassium, kuvuselela inqubo yokungena kwalezi zingxenye emangqamuzaneni omzimba.
I-Dibicor inqunyelwe, njengoba ukubuyekezwa okuningi kukhombisa ukwephula ibhalansi ye-phospholipid, into isebenza kangcono ukusebenza kwazo zonke izitho zangaphakathi.
Ngenxa yokuthi umuthi uyi-neurotransmitter enhle kakhulu, unomphumela omuhle kakhulu ekusebenzeni kohlelo lwezinzwa.
Kungakho umuthi ubekelwe izinkinga ezinkingeni yokusebenza kwenhliziyo kanye nomfutho wegazi ophakeme, ovame ukuhambisana nesifo sikashukela.
Kunezimo lapho i-Dibicor ne-Metformin zisiza abaguli abagugile abanezinkinga ezisobala noshukela.
Umphumela omuhle wokusetshenziswa wenzeka ikakhulukazi ngenxa yokuthi into esemqoka yokusebenza komuthi, okungukuthi i-taurine, inezici zokuvikela ulwelwesi futhi olungafani nhlobo. Ngokulashwa okujwayelekile nangokufanele, umzimba wesiguli ululama ngokushesha futhi zonke izinqubo ezibalulekile zibuyele kokujwayelekile, kufaka phakathi imetabolism. Futhi konke lokhu kwenzeka ezingeni lamaselula.
Ngokuqondene nokuthi iyiphi i-Dibicor ene-contraindication, ikhathaza kuphela lezo ziguli ezinenkinga ngokubekezelela ngakunye kwazo zonke izakhi zomuthi noma into esebenzayo esebenzayo.
Lokhu kusebenza nemiphumela emibi, kwenzeka ikakhulu ngokungabekezelelani komuntu ngamunye ezingxenyeni zomuthi.
Imiyalo yokusebenzisa umuthi
Kuhlangana ngani isifo sikashukela ne-dibicor? Kulokhu, kunomthelela oyinkimbinkimbi emzimbeni wesiguli. Iziguli eziningi ezinenkinga kashukela zivame ukuba nokuphazamiseka ohlelweni lwezinhliziyo nezinqubo ze-metabolic zithikamezekile. Inkambo yokwelashwa, okubandakanya ukusetshenziswa kwe-Dibikor okungenani izinyanga eziyisithupha, isiza ukuthuthukisa inhlala-kahle yomuntu kaningana, amazinga omfutho wegazi lakhejwayelekile, uhlelo lwenhliziyo nezinye izinhlelo ezibalulekile zisebenza zizinzile ngokwengeziwe.
Ukuphela kwento ebalulekile okufanele uyikhumbule uma uhlanganisa lesi sidakamizwa nezinye izidakamizwa, umphumela ungahluka, ikakhulukazi uma kukhulunywa nganoma yisiphi izifo zenhliziyo.
Kumele kuqashelwe ukuthi umphumela wento eyelapha yokwelapha unomphumela omuhle kakhulu ekungazigcinini kwabantu. Ukuthuthukiswa kokusebenza kwe-metabolism kanye nokujikeleza kwegazi nakho kwaphawulwa.
Uma i-Glucophage ithathwa nalo muthi, khona-ke kukhona ukuthuthuka ngasikhathi sinye ekusebenzeni kwenhliziyo kanye nokwehla kwamazinga eglucose.
Ngokuyisisekelo, ukwehluleka kwenhliziyo kwenzeka ngenxa yokulahleka kwama-ion we-potassium emzimbeni, ngakho-ke ukusetshenziswa kwomuthi ongenhla kuzosiza ukuvimbela lo mphumela.
Ithuluzi lingathathwa neminye imithi. Kepha kungakuhle ukuthi ungakuhlanganisi nezidakamizwa zenhliziyo.
Ngokusetshenziswa njalo, inqubo ye-adrenaline rush iqala ukujwayezeka emzimbeni wesiguli, ukuhlangana kwama-hormone, kufaka phakathi i-prolactin, kuzinzile.
Imiphumela emibi nokusebenzisana nezinye izidakamizwa
Sekushiwo ngenhla ukuthi umuthi uwuthinta kanjani umzimba, manje kubalulekile ukukhuluma ngokuthi uwuthatha kanjani umuthi ukuze izakhiwo zawo zibonakaliswe kahle ngangokunokwenzeka.
Eqinisweni, kubaluleke kakhulu ukukhumbula ukuthi umuthi awunawo imiphumela ekhethekile, kodwa noma kunjalo udinga ukuwuthatha kuphela enconyweni kadokotela nangesilinganiso esinqunywe udokotela.
Isichasiselo kulo muthi sithi ukusetshenziswa njalo kwento yokwelapha kunciphisa kakhulu i-acidity futhi kuthuthukisa nokugeleza kwegazi kwangaphakathi. Kunconywa ushintsho lokudlulisela esibindini. Ukusetshenziswa kwomuthi kunciphisa amathuba wezimpawu zokuqala ze-cirrhosis.
Ngokuphathelene nalokho umuthi okunikeza ngesikhathi sokwelapha isifo sikashukela, kubalulekile ukuqaphela ukuthi kusebenza impela kuleli cala. Ngempela, cishe zonke iziguli ezitholakala zinesifo sikashukela zinezinkinga ezisobala ngomsebenzi wohlelo lwezinhliziyo nesibindi. Izici ezinhle zezinto zokwelapha, okuhloswe ngazo ukwenza ngcono izinqubo ze-metabolic, zizosiza ezigulini ezinesifo "sikashukela".
Ngaphezu kwalokho, kukhona intuthuko ngombono. Ngemuva kwakho konke, lo muthi uphatha cishe zonke izinqubo ezibalulekile emzimbeni, kubandakanya nokujwayelekile uhlelo lokujikeleza kwegazi nokujwayela umfutho wegazi.
Ngokungafani neminye imithi yokwelapha, lo muthi awunamphumela omubi, uhambisana kahle nezidakamizwa ezinciphisa ushukela, okufanele futhi ziphuzwe njalo ngabanesifo sikashukela.
Mayelana nokuhlanganiswa kwezidakamizwa, kufanele uqale uthintane nodokotela wakho.
Ungaqali ukwelashwa ngokwakho.
Ukubuyekezwa nezincomo zodokotela
Ukubuyekezwa okuningi kodokotela kukhombisa ukuthi lesi sidakamizwa sinomsebenzi wokuzivikela emzimbeni womuntu. Uma kusetshenziswa namanye ama-glycosides nemithi esetshenziselwa ukuvimba iziteshi ze-calcium. I-taurine enkulu yezithako ezisebenzayo isiza ukuthuthukisa isibindi, uma ukwelashwa kwenziwa ngosizo lwemithi ye-antifungal.
Umthamo othize wamathebulethi ubekwe kwimiyalo, ulawulwa ngudokotela ohambelayo. Kodwa, uma weqa umthamo ovumelekile wento, khona-ke ngokoqobo emavikini ambalwa kuzokwazi ukunciphisa kakhulu izinga le-glucose egazini lesiguli.
Kubalulekile ukuqaphela ukuthi kukhona amaphilisi aqukethe i-250 mg yento esemqoka esebenzayo, futhi kukhona lezo lapho i-500 mg ikhona, lapho uthenga lo muthi, kufanele njalo unake umthamo.
Umuthi kufanele uphuzwe cishe ikota yehora ngaphambi kokudla, kaningi ngosuku.
Njengoba sekushiwo, lapho kunesifo sikashukela i-mellitus, into kumele isetshenziswe ihlangene nezinye izidakamizwa ezinciphisa ushukela kanye ne-insulin therapy.
Noma yisiphi isiguli singavula imiyalo yalo muthi ngaphambili futhi sibone incazelo eningiliziwe yokuthi ungawasebenzisa kanjani kahle la maphilisi futhi uthintane nodokotela wakho kusengaphambili.
Analogs nezici isicelo
Ngokuphathelene nezici zokusetshenziswa kwomuthi, kubalulekile ukuqaphela ukuthi esimweni sokwelashwa okuyinkimbinkimbi sohlobo lwe-1 mellitus yesifo sikashukela, kwanele ukuthatha umuthi kabili ngosuku ngethamo lika-250 mg liye kweliphezulu lama-500 mg. Kepha lapho uhlobo lokuqala lwesifo sikashukela selashwa, khona-ke kuyadingeka ukuthi uphuze ngqo u-500 mg wesidakamizwa kabili ngosuku. Kulokhu, kuzo zombili lezi zimo, kuyadingeka ukuhambisana nohlelo lokwamukela - okungenani ihora nesigamu ngaphambi kokudla.
Umuthi ugcinwa endaweni yokushisa engeqi ngamashumi amabili nesithupha degrees, ngaphandle kwezingane nezilwane.
Kucace bha ukuthi namhlanje kunezincazelo ezihlukile zalesi sikhungo sokwelapha esingasetshenziselwa ukuxilongwa okufanayo. Lolu hlu lubandakanya:
- I-Mildronate;
- Taufon;
- Mildrazine;
- Kapikor nabanye abaningi.
Kuliqiniso, akumelanga sikhohlwe ukuthi isinqumo sokufaka omunye umuthi wokwelapha kwesinye senziwa kuphela emva kokubonisana nodokotela kwangaphambilini. Awusoze wazijikisa ngokuzimela umuthi owodwa komunye.
Mayelana nenqubomgomo yamanani entengo yesidakamizwa, kufanele kubhekwe lapha ukuthi izindleko zomuthi othile zincike ekutheni umenzi wakhiqiza luphi izwe umuthi. Isibonelo, abalingani bakwamanye amazwe babiza kakhulu kunemikhiqizo yasekhaya. Yize isithako esikhulu esisebenzayo siyefana kumathebulethi akhiqizwa phesheya nasemikhiqizweni yasekhaya.
Kwesinye isikhathi umuntu unezinhlobo ezahlukahlukene zokungezwani nokwenzeka ku-mellitus yesifo sikashukela kumuthi othize. Lokhu kungenzeka ngenxa yezici ezingeziwe ezifakiwe ekwakhiweni kwethuluzi. Esimweni esinjalo, ukufaka umuthi esikhundleni se-analogue kungasiza ukulungisa isimo samanje.
Ngakho-ke, uma phakathi nokwelashwa, isiguli siqala ukuzwa noma yiziphi izinguquko ezingezinhle empilweni yaso, kufanele siqhubeke sibonane nodokotela wakhe. Mhlawumbe kwanele ukumane ushintshe leli thuluzi nge-analogue yalo.
Izinzuzo zeTaurine (Dibikor) zichazwe kuvidiyo kule ndatshana.
