Iziguli eziningi ezibhekene nenkinga yesifo sikashukela zinesifiso sokuthi imuphi umuthi ongasiza kakhulu inqubo yokwelapha lesi sifo.
Okunye okusebenzayo kakhulu i-drug Glibomet, enomphumela omuhle wokwehlisa ushukela, ngenxa yokuthi iqukethe izinto ezifana ne-metformin ne-glibenclamide. Ukulinganiswa phakathi kwezakhi eziphambili ze-drug glibenclamide ne-metformin kungama-400 mg no-2.5 mg, ngokulandelana. Ithuluzi liqukethe izingxenye ezisizayo.
Kuliqiniso, ukuze umphumela wokwelashwa ube mkhulu, udinga ukuqonda ukuthi uwuphuza kanjani umuthi ngendlela efanele.
Umuthi utholakala kuphela ngesimo samacwecwe, iphakethe linamathebhulethi angama-40, 60 kanye ayi-100.
Kubalulekile ukuqaphela - umuthi uthathwa isifo sikashukela sohlobo 2. Into esemqoka esebenzayo, eyingxenye yayo, inethonya ekususeni kwe-insulin, inyusa izinga lokubona kwaleli hormone emzimbeni.
Kubalulekile ukuthi i-Glibomet kanye nama-analogues alo muthi abhekwe njengesizukulwane esisha sezidakamizwa, ngenxa yokusetshenziswa kwesinye sezithako ezisebenzayo eziphambili - i-glibenclamide. I-Glibenclamide ithathwe kwisulfonylurea entsha, yesizukulwane sesibili.
Ama-analoggu alo muthi anomthelela ofanayo emzimbeni futhi anezici ezifanayo. IGlucophage ingaba isidakamizwa i-analogue; iqukethe i-glibenclamide ne-metformin.
Inzuzo enkulu yesidakamizwa ukuthi umuthi osebenza isikhathi eside, uvame ukunikezwa abantu abasha nezingane.
Ngenxa yenhlanganisela ephumelelayo yezingxenye ezimbili eziyinhloko, ngenxa yokuthatha i-glibenclamide ne-metformin, kungenzeka ukufeza umphumela omuhle okwehlisa ushukela futhi unqobe isisindo ngokweqile. Inkinga yesisindo ngokweqile ivame ukuhambisana nesifo sikashukela sohlobo 2.
Umphumela womuthi emzimbeni
Ucwaningo oluningi olwenziwe ochwepheshe bomhlaba selufakazele ukuthi isenzo somuthi, esine-INN esibizwa ngeMetformin, siqala amahora amabili ngemuva kokuwusebenzisa, futhi siphela ngemuva kwamahora ayi-12. Kwanele ukuthi isiguli sithathe kabili ngosuku ukuqinisekisa impilo entofontofo nempilo enhle. Isiguli kufanele siqonde ukuthi ungakanani umuthi okufanele uphuzwe nezinhlobo ezahlukahlukene zesifo sikashukela.
Ezinye iziguli zikhononda ngemiphumela emibi evela ekusetshenzisweni kwalo muthi, kwenzeka esigulini lapho kukhona ukungabekezelelani ngakunye kuya ezingxenyeni zomuthi. Kubalulekile ukuhlaziya kusengaphambili ukuhambisana komzimba womuntu nezakhi zomuthi bese uqala ukwelashwa.
Ngemuva kokuthatha iphilisi, umzimba uzoqala ukuhlanganisa i-insulin ngokushesha. Ngemuva kokuthatha umuthi, uhlanganiswa kaninginingi ukwedlula ngaphambi kokuqala kokwelashwa. Isithako esiyisisekelo esisebenzayo sinomphumela we-pancreatic emzimbeni womuntu, kepha i-biguanide ekhona emithini inomphumela owengeziwe we-pancreatic - inqubo esebenzayo yokuthathwa koshukela ngumzimba wesiguli izoqala.
Ezinye iziguli zikholelwa ukuthi ukululama okusebenzayo kwanele ukuphuza imithi ethile futhi impilo izothuthuka. Akwanele ukuya kudokotela futhi umtshele okuthile okufana nokuthi ungasiza yini ukuqeda isifo sikashukela noma ungitshele, ngicela, iphilisi elisebenza kakhulu futhi ngasikhathi sinye ukusebenzisa, ngokwesibonelo, utshwala. Lapho uqeda ukugula, kubalulekile ukulandela indlela efanele yokudla bese ulayisha umzimba ngomsebenzi owanele womzimba. Musa ukulayisha ngokweqile umzimba akufanele.
Uma isiguli sihlanganisa ngokufanele ukusetshenziswa kwemithi, ukudla okulinganiselayo kanye nokuzivocavoca umzimba, khona-ke ungathola umphumela omuhle.
Contraindication ukusetshenziswa kwezokwelapha
Kubalulekile ukwethemba udokotela wakho hhayi imibono yezinye iziguli.
Ukuhlanganiswa kwe-glibenclamide ne-metformin kuzosiza ukugcina izinga loshukela womzimba ebangeni elamukelekayo kumuntu.
Njenganoma yimuphi omunye umuthi, i-glibomet equkethe i-glibenclamide ne-metformin ine-contraindication ethile.
I-contraindication eyinhloko ekusebenziseni umuthi yile elandelayo:
- Uhlobo 1 sikashukela;
- isikhathi se-lactic acidosis;
- isimo sikashukela noma sokuhlangana;
- izifo ezihambisana nokuphulwa kwenqubo yokutholwa kokudla;
- ukutheleleka okuyinkimbinkimbi okungadala ukukhula kokuhluleka kwe-renal;
- Izinkinga ezisebenza kwesibindi nokunye okuningi.
Umzimba womuntu onesifo sikashukela uhlushwa izifo eziningi ezimbi kanye nokuphazamiseka kwengqondo ekusebenzeni kwezitho zangaphakathi, ukhula ngokumelene nesizinda sesifo esikhona. Ngakho-ke, ngaphambi kokuqala ukwelashwa kwezifo eziyinhloko nanoma yisiphi isidakamizwa, kubalulekile ukuhlola umzimba ukuthola ukuthi isiguli sinemiphumela emibi nemiphumela emibi evela ekuphuzeni umuthi.
Kubalulekile ukuqonda ngqo ukuthi yiluphi uhlobo lomuthi olufanele isiguli esithile, kungenzeka ukuthi ukhethe i-analogue yomuthi. Ngokuqondene ne-analogue, ukunakekelwa kufanele kuthathwe ukuze ukhethe okufanele kakhulu. Odokotela abaningi batusa ukuthi iziguli ziwushintshe umuthi uma kwenzeka kuvela imiphumela emibi. IGlucophage ithandwa njenge-analogue, enomphumela ofanayo emzimbeni wesiguli.
Ukukhetha umuthi osebenza kakhulu, kunconywa, lapho ukhetha umuthi, ukutadisha ngokuningiliziwe imiyalo yokusebenzisa umuthi kanye nokubuyekezwa kweziguli ngakho. Ukutadisha imiyalo yokusebenzisa umuthi i-Glibomet nokubuyekezwa kwesiguli ngakho kusivumela ukuthi siqonde zonke izici zokusetshenziswa komkhiqizo ochaziwe futhi senze ukusetshenziswa kwawo kube okungenabungozi futhi okusebenzayo ngangokunokwenzeka.
Ngaphambi kokuthenga umuthi, i-Glybomet iyadingeka ukuze uzijwayeze nemiyalo esetshenzisiwe, imininingwane enjalo iyatholakala kwi-Intanethi, uma ifunwa, noma ngubani angajwayelana nganoma yisiphi isikhathi.
Ukuboniswa kwemiphumela emibi
Ithuluzi linemikhawulo yobudala. Iziguli ezingaphansi kweminyaka eyishumi nesishiyagalombili ubudala azinconywa ukuthi zisetshenziswe.
Umuthi ungathengwa kunoma iyiphi ikhemisi eRussia. Udinga ukwenza lokhu ngemuva kokubonisana nodokotela wakho futhi uthole nemiyalelo evela kuye. Okufanayo kusebenza ezimweni lapho isiguli sithatha isinqumo sokushintsha umuthi nge-analogue.
Ukufakwa kabusha kwalo muthi kungenziwa ngemuva kokuhlolwa udokotela futhi ngokuncoma kwakhe. Ukuqapha kuhlotshaniswa neqiniso lokuthi isithako esiyisisekelo esisebenzayo yi-metformin, eba, uma kwenzeka ngokweqile, imbangela yokuqalwa kwesigaxa sikashukela esigulini. IGlybomet ayikufanele ukuqala umuthi ngokwakho.
Ngokusekelwe kulo lonke ulwazi oluchazwe ngenhla, ukuthatha umuthi i-Glibomet kumathebulethi kungahle kuhambisane nemiphumela emibi efana:
- Ikhanda elinamandla nabol.
- Isifo sikashukela
- Izinkinga zegazi (ukuchitheka kwegazi, njll.).
- Ukonakala kwesistimu yezinzwa ephakathi.
- Ukusabela okwenziwa isikhumba nokunye okuningi.
Ngakho-ke, ekutholaka kokuqala kwezimpawu ezinjalo ngemuva kokuthatha i-Glibomet, kufanele uthintane nodokotela ngokushesha futhi, uma kunesidingo, ngokushesha funa ukuthola okunye esikhundleni salomuthi, ngaphandle kwalokho ungalimaza impilo yakho ngokwengeziwe.
Imiyalo yokusebenzisa umuthi
Akubuhlungu kangako ukuthi umbuzo ungalithatha kanjani ithuluzi elingenhla. Imininingwane yokuthi ungayithatha kanjani i-Glibomet ngendlela efanele inganikezwa ngudokotela wakho. Nguye kuphela, ngemuva kokuhlolwa kahle kwesiguli sakhe, ongancoma irejimenti yokwelashwa etshela ukuthi umthamo womuthi kufanele ube yini nokuthi uhlelo lokuphatha luyini.
Ekuqaleni kokwelashwa, kuthathwa isilinganiso sobuncane, sisuka kuthebhulethi elilodwa kuya kwamathathu. Lapho-ke, uma kunesidingo, lomthamo unganda. Isibalo esikhulu samathebhulethi umuntu oyedwa angawathatha phakathi nosuku akufanele wedlule izingcezu eziyisithupha.
Lokhu kuchazwe ngokuningiliziwe yisichasiselo kulo muthi, esinamathiselwe kwiphakheji ngalinye lomuthi. Kepha aqukethe kuphela umthamo ofanele, kodwa futhi nokwakheka okuqondile komkhiqizo. Ngakho-ke, uma isiguli singadabuki kunoma iyiphi ingxenye, singakwazi ukwazisa udokotela wakhe ngaphambi kwalokhu, njengoba kade ifunde imiyalo.
Ngokuphathelene nentengo yomuthi, ingahluka kancane kuye ngokuthi ingakanani into esebenzayo equkethwe umuthi. Ngokwesilinganiso, izindleko zivela kuma-ruble angamakhulu amabili kuya kwamakhulu amathathu.
I-Glibomet 2.5 ishibhile kancane kunomkhiqizo ofanayo, ohlanganisa i-5 mg yento esemqoka, okungukuthi i-Glibomet 5 +400.
Yini ebalulekile okufanele uyikhumbule lapho usebenzisa i-Glibomet?
Ngaphambi kokuthi uqale usebenzise umuthi i-Glibomet, imiyalo kufanele ifundwe ngemininingwane eminingi, udinga ukufunda isithombe sokufakwa kwemithi ukuze uqonde ngokunembile ukuthi umuthi uthengiwe yini.
Njengoba kushiwo ngenhla, ziningi izifaniso ezinganconywa odokotela. Phakathi kwazo, umuthi oyinhloko yi-Glucofage 850. Iziguli eziningi zizama ukuthola ukuthi yikuphi okungcono kulawa makhambi amabili. Kunzima ukunikeza impendulo eqondile. Konke kuncike ezicini zomzimba wesiguli kanye nobunzima besifo.
Ukuba khona kwezifo ezibumbana nakho kudlala indima enkulu. Uma kunezinkinga ngesibindi, khona-ke kufanele uqaphele lapho unquma ukwelashwa. Kungcono kuleli cala ukuhlala udla izidakamizwa ngokufana ezixhasa isibindi uqobo, ngokwesibonelo, i-Essentiale forte. Ngaphezu kwalokho, ukuxhumana kwalesi sidakamizwa nge-hypoglycemic kuyinto enhle impela. Iseluleko esifanayo singanikezwa mayelana nohlobo lokwelashwa, olusikisela ukuthi udinga ukuthatha i-glucophage.
Sekushiwo ngenhla ukuthi i-Glibomet ende ayinconywa ukusetshenziswa iziguli ezingaphansi kweminyaka engu-18. Ngakho-ke, uma kunesidingo sokukhetha umuthi wengane, leli qiniso kufanele libhekwe.
Kunezindlela eziningi zokwelapha lapho uManinil ekhona. Ngakho-ke, ungahlala ukhetha inkambo efanelekile yokwelashwa isiguli esithile.
Ezinye iziguli zicabanga ukuthi i-Glucophage ne-Glybomet zingamagama afanayo. Kepha lokhu kungumbono ongaqondile, lezi izidakamizwa ezimbili ezingafani, yize kukhona ukufana okuningi phakathi kwazo. Ngaphezu kwalokho, zombili ukwakheka nangokwemiphumela yomphumela emzimbeni.
Kufanele ngaso sonke isikhathi ukhethe ngokucophelela umthamo womuthi ngokuya ngohlobo oluncamelwayo lokwelashwa. Ngemuva kwakho konke, kukhona amaphilisi aqukethe i-2.5 mg yento esebenzayo, futhi kukhona lawo afaka i-5 mg yento efanayo.
Imiphi imishanguzo yesifo sikashukela esebenzayo kakhulu echazwe kuvidiyo kule ndatshana.
