Njengoba wazi, ushukela unezinhlobo ezimbili - uthembele ku-insulin (ubizwa nangokuthi uhlobo 1) nokungathembeki kwe-insulin (izinhlobo ezi-2). Le pathology ingakhula ngenxa yezizathu eziningi.
Kuhlobo 1 nesifo sikashukela sohlobo 2, inqubo yokusebenzisa ushukela ezicutshini iyaphazamiseka. Ukuze amazinga okujwayelekile kashukela abejwayelekile, kuyisiko ukusebenzisa umuthi okhethekile. Futhi, ngesifo sikashukela sohlobo 1 nohlobo 2, kufanele ulandele ukudla okuyisipesheli, okunikeza ukusetshenziswa okwehlisiwe kwama-carbohydrate.
Kubaluleke kakhulu ukuhlela indlela odla ngayo ngendlela yokuthi uzothola izakhamzimba ezanele. Kufanele ufake phakathi ekudleni kwakho ukudla okunothile i-lipoic acid.
Le nto inomphumela we-antioxidant. I-Lipoic acid yesifo sikashukela iyasiza kakhulu, ngoba iqinisa isistimu ye-endocrine futhi isiza ukuguqula ushukela wegazi ngokujwayelekile.
Indima ye-lipoic acid emzimbeni
I-Lipoic noma i-thioctic acid isetshenziswa kabanzi kwezokwelapha. Izidakamizwa ezisuselwa kule nto zisetshenziswa kabanzi ngesikhathi sokwelashwa kukashukela wohlobo 1 nohlobo 2. Futhi, izidakamizwa ezinjalo zisetshenziswa ekwelashweni okuyinkimbinkimbi kwama-pathologies amasosha omzimba nezifo zomgudu wokugaya ukudla.
I-Lipoic acid yahlukaniswa okokuqala kwesibindi sezinkomo ngo-1950. Odokotela bathole ukuthi leli khompiyutha linomphumela omuhle enqubweni yamaprotheni asemzimbeni.
Kungani i-lipoic acid isetshenziselwa uhlobo 2 sikashukela? Lokhu kungenxa yokuthi into inezakhiwo eziningi ezisebenzayo:
- I-Lipoic acid ibandakanyeka ekuqhekekeni kwama-molecule eglucose. Umsoco ubandakanyeka nenqubo ye-ATP energy synthesis.
- Umuthi yi-antioxidant enamandla. Ekusebenzeni kwayo, ayinciphisi i-vitamin C, i-tocopherol acetate kanye ne-oyela yezinhlanzi.
- I-Thioctic acid isiza ukuqinisa ukungatheleleki.
- I-Nutrient inempahla okuthiwa i-insulin. Kwatholakala ukuthi le nto inomthelela ekwandeni komsebenzi wezithwali zangaphakathi zamamolekyuli e-cytoplasm. Lokhu kuthinta kahle inqubo yokusebenzisa ushukela kwezicubu. Yingakho i-lipoic acid ifakwa emithini eminingi yesifo sikashukela sohlobo 1 nohlobo 2.
- I-Thioctic acid yenyusa ukumelana komzimba nemiphumela yamagciwane amaningi.
- I-Nutrient ibuyisela ama-antioxidants angaphakathi, kufaka phakathi i-glutatitone, i-tocopherol acetate ne-ascorbic acid.
- I-Lipoic acid inciphisa imiphumela enobuthi yobuthi emalungeni amaseli.
- I-Nutrient iyi-sorbent enamandla. Kufakazelwe ngokwesayensi ukuthi into ibopha ubuthi namabili wezinsimbi ezisindayo kuzakhiwo ze-chelate.
Ekuhlolweni okuningi, kwatholakala ukuthi i-alpha lipoic acid yandisa ukuzwela kwamangqamuzana ku-insulin. Lokhu kubaluleke kakhulu kwisifo sikashukela sohlobo 1. Umuthi futhi usiza ukwehlisa isisindo somzimba.
Leli qiniso laqinisekiswa ngokwesayensi ngonyaka we-2003. Ososayensi abaningi bakholelwa ukuthi i-lipoic acid ingasetshenziselwa ushukela, ohambisana nokukhuluphala.
Yikuphi ukudla okuqukethe izakhi
Uma umuntu enesifo sikashukela, khona-ke kufanele alandele indlela yokudla. Ukudla kufanele kube ukudla okunothe ngamaprotheni kanye ne-fiber. Futhi, kuyimpoqo ukudla ukudla okuqukethe i-lipoic acid.
Isibindi senkomo sinothile kuleso sakhi. Ngaphezu kwe-thioctic acid, iqukethe ama-amino acid azuzisayo, amaprotheni kanye namafutha angagciniwe. Isibindi senkomo kufanele sidliwe njalo, kepha ngamanani amancane. Usuku akufanele lusetshenziswe kungabi ngama-gramu ayi-100 alo mkhiqizo.
Ama-lipoic acid amaningi atholakala ku:
- Okuzala. Lesi sakhi sinothile ku-oatmeal, ilayisi yasendle, ukolweni. Okuwusizo kakhulu okusanhlamvu yi-buckwheat. Ine-thioctic acid ephezulu kakhulu. IBuckwheat nayo icebile ngamaprotheni.
- I-Legumes. Amagremu ayi-100 ama-lentil aqukethe ama-450-460 mg we-asidi. Cishe ama-300-400 mg wezakhamzimba aqukethe ku-100 amagremu wophizi noma ubhontshisi.
- Imifino emisha. Iqembu elilodwa lesipinashi libalelwa ku-160-200 mg ye-lipoic acid.
- Amafutha wefilakisi. Amagremu amabili alo mkhiqizo aqukethe cishe i-10-20 mg ye-thioctic acid.
Yidla ukudla okuqukethe lo mnongo, kuyadingeka ngesilinganiso esilinganiselwe.
Ngaphandle kwalokho, amazinga kashukela wegazi angakhuphuka kakhulu.
Ukulungiselela kwe-Lipoic Acid
Yiziphi izidakamizwa ezifaka i-lipoic acid? Le nto iyingxenye yezidakamizwa ezifana neBerlition, Lipamide, Neuroleptone, Thiolipone. Izindleko zale mishanguzo azidluli ama-650-700 rudders. Ungasebenzisa amaphilisi ane-lipoic acid yesifo sikashukela, kodwa ngaphambi kwalokho kufanele ubonane nodokotela wakho.
Lokhu kungenxa yokuthi umuntu ophuza lezi zidakamizwa angadinga i-insulin encane. Ukulungiswa okungenhla kuqukethe kusuka ku-300 kuye ku-600 mg we-thioctic acid.
Ngabe isebenza kanjani le mishanguzo? Isenzo sabo semithi siyefana. Imithi inomphumela wokuvikela kumaseli. Izinto ezisebenzayo zemithi zivikela ama-membrane amaseli emiphumeleni yama-radical asebenzayo.
Izinkomba zokusetshenziswa kwezidakamizwa ezisuselwa ku-lipoic acid yilezi:
- I-mellitus engavikelekile ye-insulin (uhlobo lwesibili).
- I-mellitus encike kwisifo sikashukela (uhlobo lokuqala).
- I-pancreatitis
- Isifo sokuqina kwesibindi.
- Isifo sikashukela se-polyneuropathy.
- Ukonakala kwamafutha kwesibindi.
- I-coronary atherosclerosis.
- Ukwehluleka kwesibindi okungamahlalakhona.
I-Berlition, i-Lipamide nezidakamizwa ezivela kule ngxenye kusiza ukunciphisa isisindo somzimba. Kungakho imithi ingasetshenziswa ekwelapheni isifo sikashukela sohlobo 2, esasibangelwa ukukhuluphala. Imithi ivunyelwe ukuphuzwa ngesikhathi sokudla okuqinile, okubandakanya ukuncishiswa kokudla okungama-caloric aze afike kilojoule ayi-1000 ngosuku.
Kufanele ngiyithathe kanjani i-alpha lipoic acid yesifo sikashukela? Umthamo wansuku zonke ngu-300-600 mg. Lapho ukhetha umthamo, umuntu kufanele acabangele iminyaka yesiguli kanye nohlobo lwesifo sikashukela. Uma amalungiselelo e-lipoic acid esetshenziselwa ukwelapha ukukhuluphala, umthamo wansuku zonke uncishiselwa ku-100-200 mg. Isikhathi sokwelashwa okwelashwa imvamisa siyinyanga eyi-1.
Contraindication nokusetshenziswa kwezidakamizwa:
- Isikhathi sokuzala.
- Allergy to thioctic acid.
- Ukukhulelwa
- Iminyaka yezingane (kuze kube iminyaka eyi-16).
Kuyaqapheleka ukuthi izidakamizwa zalolu hlobo zithuthukisa umphumela we-hypoglycemic we-insulin esebenza kancane. Lokhu kusho ukuthi ngesikhathi sokulashwa, umthamo we-insulin kufanele ulungiswe.
I-Berlition kanye ne-analogues yayo akunconyelwe ukuba kuthathwe ngokuhambisana namalungiselelo afaka ama-iron ion. Ngaphandle kwalokho, ukusebenza kahle kokwelashwa kungancishiswa.
Uma usebenzisa umuthi osuselwa ku-lipoic acid, imiphumela emibi efana:
- Isifo sohudo
- Ubuhlungu besisu.
- Isicanucanu noma ukuhlanza.
- Ukugoqeka kwemisipha.
- Khuphula umfutho we-intracranial.
- I-Hypoglycemia Ezimweni ezimbi kakhulu, kuhlaselwa i-hypoglycemic yesifo sikashukela. Uma kwenzeka, isiguli kufanele sinikezwe usizo ngokushesha. Kunconywa ukusebenzisa isixazululo se-glucose noma unamathisele nge-glucose.
- Ubuhlungu bekhanda.
- IDiplopia
- Izikhala zokuphefumula.
Uma kwenzeka kuba ne-overdose, kungadalwa ukungezwani komzimba, kuze kufike ekuqhekekeni kwe-anaphylactic. Kulokhu, kuyadingeka ukugeza isisu uthathe i-antihistamine.
Futhi yini ukubukezwa mayelana nale mishanguzo? Abathengi abaningi bathi i-lipoic acid iyasebenza kushukela. Izidakamizwa ezenza le nto zisize ukumisa izimpawu zesifo. Futhi, abantu bathi uma usebenzisa izidakamizwa ezinjalo, amandla ayanda ayanda.
Odokotela baphatha i-Berlition, i-Lipamide nezidakamizwa ezifanayo ngezindlela ezihlukile. Iningi lama-endocrinologists likholelwa ukuthi ukusetshenziswa kwe-lipoic acid kufanelekile, ngoba into isiza ekuthuthukiseni ukusetshenziswa kwe-glucose kwezicubu.
Kepha abanye odokotela banombono wokuthi izidakamizwa ezisuselwa kule nto ziyi-placebo ejwayelekile.
I-Lipoic acid ye-neuropathy
I-Neuropathy iyindlela yokusebenza lapho ukusebenza okuvamile kohlelo lwezinzwa kuphazamiseka khona. Imvamisa, lokhu kugula kuvela ngohlobo 1 nesifo sikashukela sohlobo 2. Odokotela bathi lokhu ngesifo sikashukela, ukuphuma kwegazi okujwayelekile kuyaphazamiseka kanti nokuhamba kokuqina kwezinzwa kuyawohloka.
Ngokuthuthukiswa kwe-neuropathy, umuntu uhlangabezana nokuqina kwamalunga nemilenze, ikhanda nokuqhaqhazela kwesandla. Izifundo eziningi zemitholampilo ziveze ukuthi ngesikhathi kuqhubeka le-pathology, ama-radicals mahhala adlala indima enkulu.
Yingakho abantu abaningi abanesifo sikashukela se-neuropathy benqunywa i-lipoic acid. Le nto isiza ukuqinisa isistimu yezinzwa, ngenxa yokuthi iyi-antioxidant enamandla. Futhi, izidakamizwa ezisuselwa ku-thioctic acid zisiza ukuthuthukisa ukuqhutshwa kokushayelwa kwezinzwa.
Uma umuntu eba nesifo sikashukela se-diabetes, khona-ke kufanele:
- Yidla ukudla okunothe i-lipoic acid.
- Phuza ama-vitamin complexes ahlanganiswe nemithi ye-antidiabetic. I-Berlition ne-Tiolipon ziphelele.
- Ngezikhathi ezithile, i-thioctic acid iphathwa ngaphakathi (lokhu kufanele kwenziwe ngaphansi kokubhekwa kwezokwelashwa okuqinile).
Ukwelashwa ngesikhathi kunganciphisa amathuba okudlondlobala kwe-autonomic neuropathy (i-pathology ehambisana nokuphulwa kwesigqi senhliziyo). Lesi sifo sibonisa abanesifo sikashukela. Ividiyo ekulesi sihloko iqhubeka nengqikithi yokusetshenziswa kwe-acid kushukela.
