Ukukhuluphala kuyingozi eyaziwayo yesifo sikashukela. Kodwa-ke, ucwaningo lwakamuva lukhombisa ukuthi kubalulekile futhi ukucubungula ukuthi lawo mafutha agcinwa kuphi futhi kanjani emzimbeni.
Odokotela sekuyisikhathi eside bezazi izimo lapho ubungozi bokuthola isifo sikashukela bukhuphuka: ubudala kusukela eminyakeni engama-45 kuya phezulu, umfutho wegazi ophakeme, ukudangala, isifo senhliziyo kanye nefa (amacala okugula ezihlotsheni). Mhlawumbe isici sobungozi esaziwayo saziwa ngokweqile noma ukukhuluphala. Kepha ngokuya ngocwaningo olusha olwenziwe ososayensi baseBrithani nabaseMelika, ngamafutha, yize ngokuqinisekile kuyinto enobungozi, akulula kangako.
Amafutha wokusabalalisa Amafutha
Esikhungweni sokufunda esivele sishiwo kwakuyi-gene ebizwa nge-KLF14. Yize kucishe kungathinti isisindo somuntu, kepha lolu hlobo lokunquma ukuthi izogcinwa kuphi izitolo ezinamafutha.
Kwatholakala ukuthi kwabesifazane, ukuhlukahluka okuhlukile kwe-KLF14 kusabalalisa amafutha kumadepho anamafutha noma okhalweni noma esiswini. Abesifazane banamaseli amancane kakhulu (ukumangala!), Kepha bakhulu futhi ngokwempela "bagcwele" amafutha. Ngenxa yalokhu kuqina, izinqolobane ezinamafutha zigcinwa futhi zidliwe ngumzimba ngokungasebenzi, okungenzeka ukuthi kunomthelela ekuqubukeni kokuphazamiseka kwe-metabolic, ikakhulukazi isifo sikashukela.
Abaphenyi bathi uma amafutha amaningi egcinwe okhalweni, ayibandakanyeki kakhulu ezinqubweni ze-metabolic futhi ayikhulisi ingozi yokuba nesifo sikashukela, kodwa uma “izinqolobane” zayo zigcinwa esiswini, lokhu kuyandisa kakhulu ingozi engenhla.
Kubalulekile ukuqaphela ukuthi ukuhlukahluka okunjalo kofuzo lwe-KLF14, okudala ukuthi izitolo ezinamafutha zitholakale endaweni okhalweni, kwandisa ingozi yokuba nesifo sikashukela kuphela kulabo besifazane okwazuzwe ifa labo sivela komama. Ubungozi babo buphakeme ngama-30%.
Ngakho-ke, kwacaca ukuthi ngokuthuthukiswa kwesifo sikashukela, hhayi kuphela isibindi namanyikwe akhiqiza i-insulin, kodwa namaseli aqatha.
Kungani lokhu kubalulekile?
Ososayensi kuze kube manje ukuthola ukuthi kungani lolu hlobo luthinta imizwa yokudla emzimbeni kuphela kubantu besifazane, nokuthi kungenzeka yini ukuthi ngandlela thile basebenzise idatha emadodeni.
Kodwa-ke, sekucacile ukuthi ukutholakala okusha kuyisinyathelo ekuthuthukiseni umuthi owenziwe umuntu uqobo, okungukuthi, umuthi osuselwa kuzinhlobo zofuzo eziguli. Le nkomba isencane, kepha iyathembisa kakhulu Ikakhulu, ukuqonda indima yohlobo lwe-KLF14 kuzovumela ukuthi isifo sangaphambi kwesikhathi sihlole ubungozi bomuntu othize futhi kuvikele ukuqala kwesifo sikashukela. Isinyathelo esilandelayo kungaba ukuguqula lo gene futhi ngaleyo ndlela unciphise ubungozi.
Okwamanje, ososayensi bayasebenza, nathi, singakwazi ukuqala umsebenzi wokuzivikela emizimbeni yethu. Odokotela bakusho ngokungakhathali ngezingozi zokukhuluphala ngokweqile, ikakhulukazi uma kukhulunywa ngamakhilogremu okhalweni, futhi manje sinesiphikiso esisodwa sokunganaki ukuqina komzimba kanye nokuzivocavoca umzimba.
