IGensulin iyisisombululo somuthi sokujova isifo sikashukela. Kuphikisiwe uma kwenzeka uzwela ngokweqile kukho, kanye ne-hypoglycemia.
Imiyalo yokusebenzisa kanye nomthamo
Umthamo othize kanye nendlela yokuphatha izonconywa kuphela udokotela ohambelayo. Umthamo uzosethwa ngokugxila ekuhlolweni kashukela wegazi kanye namahora ama-2 ngemuva kokudla. Ngaphezu kwalokho, izinga lenkambo ye-glucosuria nezimpawu zayo kuzonakwa.
IGensulin r ingalawulwa ngezindlela ezahlukahlukene (ngaphakathi, ngaphakathi, ngaphakathi) imizuzu engu-15 kuya kwengama-30 ngaphambi kokudla okuhlosiwe. Indlela ethandwa kakhulu yokuphatha i-subcutaneous. Zonke ezinye zizolunga ezimweni ezinjalo:
- nge-ketoacidosis yesifo sikashukela;
- onesifo sikashukela;
- ngesikhathi sokuhlinzwa.
Imvamisa yokuphatha ngesikhathi sokusebenzisa ukwelashwa kwezimoto izoba kathathu ngosuku. Uma kunesidingo, inani lemijovo lingakhushulwa lifinyelele ezikhathini ezi-5-6 ngosuku.
Ukuze ungathuthukisi i-lipodystrophy (i-atrophy ne-hypertrophy yezicubu ezingezansi), kuyadingeka ukuguqula indawo yomjovo njalo.
Umthamo ophakathi nsuku zonke wesidakamizwa Gensulin r uzoba:
- ezigulini zabantu abadala - kusuka ema-30 kuye kwangama-40 amayunithi (UNITS);
- ezinganeni - amayunithi ayi-8.
Ngaphezu kwalokho, ngesidingo esandayo, umthamo ojwayelekile uzoba ngu-0.5 - 1 UNITS ngekhilogremu yesisindo, noma ukusuka kuma-30 kuye kwangama-40 UNITS izikhathi ezi-3 ngosuku.
Uma umthamo wansuku zonke uzodlula ama-0.6 PIECES / kg, khona-ke kuleli cala umuthi kufanele uphathwe njengemijovo emi-2 ezingxenyeni ezahlukene zomzimba.
Umuthi uhlinzeka ngamathuba okuhlanganisa umuthi i-Gensulin r nama-insulin asebenza isikhathi eside.
Isixazululo kufanele siqoqwe kusuka ku-vial ngokubhoboza isithabisi senjoloba ngenaliti yesirinji oyinyumba.
Umgomo wokuchayeka emzimbeni
Lesi sidakamizwa sisebenzisana nama-receptors athile kulwelwesi lwangaphandle lwamaseli. Njengomphumela wokuxhumana okunjalo, kuvela i-insulin receptor complex. Njengoba ukukhiqizwa kwe-cAMP kukhuphuka kumaseli ezinamafutha nesibindi noma lapho kungena ngqo emangqamuzaneni emisipha, i-insulin receptor complex ephumayo iqala ukuvusa izinqubo ze-intracellular.
Ukwehla ushukela wegazi kubangelwa:
- ukukhula kwezokuhamba kwayo kwangaphakathi;
- ukumuncwa okuthe xaxa, kanye nokufakwa kwayo ngezicubu;
- ukugqugquzela inqubo ye-lipogenesis;
- synthesis amaprotheni;
- glycogenesis;
- ukwehla kwezinga lokukhiqizwa koshukela isibindi.
Ngemuva kokujova okufakwayo, umuthi iGensulin r uzoqala ukusebenza kungakapheli imizuzu engama-20 kuye kwengama-30. Ukuqoqwa okuphelele kwento kuzobhekwa ngemuva kwamahora angama-1-3. Isikhathi sokuchayeka kule insulin sizoncika ngqo kumthamo, indlela nasendaweni yokuphatha.
Amathuba okusabela okungekuhle
Ngenqubo yokusebenzisa i-Gensulin r ukusabela okungekuhle komzimba kungenzeka:
- i-allergies (i-urticaria, ukuphefumula, umkhuhlane, ukwehlisa umfutho wegazi);
- i-hypoglycemia (isikhumba sesikhumba, ukujuluka, ukukhukhula okwandayo, indlala, ukuthuthumela, ukukhathazeka ngokweqile, ikhanda, ukudangala, isimilo esingaziwa, ukubona okungalungile nokuxhumana);
- i-hypoglycemic coma;
- I-diabetesic acidosis ne-hyperglycemia (iba nemithamo enganele yesidakamizwa, ukweqa imijovo, ukwenqaba ukudla): I-hyperemia yesikhumba sobuso, ukwehla okukhulu kokudla, ukozela, ukoma okungapheli;
- ukungazi kahle;
- Izinkinga zombono wesikhashana;
- ukusabela kwe-immunological komzimba kuyi-insulin yomuntu.
Ngaphezu kwalokho, ekuqaleni kokwelashwa, kungahle kube nokudumba futhi kuphazamiseke okungalungile. Lezi zimpawu azivezi futhi zisheshe zinyamalale.
Izici zohlelo lokusebenza
Ngaphambi kokuthatha umuthi i-Gensulin r kusuka ku-vial, udinga ukubheka isixazululo sobala. Uma kutholwa izidumbu zakwamanye amazwe, izidakamizwa noma udoti wento ethile, kwenqatshelwe ngokuphelele ukuyisebenzisa!
Kubalulekile ukuba ungakhohlwa mayelana lokushisa ekahle ikhambi injected - kumele kube lokushisa Igumbi.
Umthamo wesidakamizwa kufanele ulungiswe uma kwenzeka ukuthuthukiswa kwezifo ezithile:
- ukutheleleka;
- Isifo sika-Addison;
- onesifo sikashukela ezigulini ezingaphezulu kweminyaka engama-65;
- nezinkinga ekusebenzeni kwe-gland yegilo;
- hypopituitarism.
Izimfuneko eziphambili zokuqalwa kwe-hypoglycemia zingaba: ukweqisa, ukuthathelwa izidakamizwa, ukuhlanza, ukucasuka kokugaya ukudla, ukuguqulwa kwesayithi lomjovo, ubunzima bomzimba kanye nokusebenzisana nezidakamizwa ezithile.
Ukwehla ushukela wegazi kungabonakala lapho ushintsha usuka ku-insulin yezilwane uye kumuntu.
Noma yiluphi ushintsho entweni ephathisiwe kufanele lube lolusemthethweni futhi lwenziwe ngaphansi kokubhekwa ngudokotela okuqine kakhulu. Uma kunenkambiso yokuthuthukisa i-hypoglycemia, khona-ke kuleli cala amandla eziguli ahlanganyele traffic traffic kanye nokugcinwa kwemishini, futhi ikakhulukazi ezimotweni, kungaba kukhubazeka.
Isifo sikashukela singamisa ngokuzimela ukuthuthukiswa kwe-hypoglycemia ethuthukayo. Lokhu kungenzeka ngenxa yokusetshenziswa kwenani lama-carbohydrate. Uma i-hypoglycemia idlulisiwe, ke kuyadingeka ukwazisa udokotela wakho ngalokhu.
Ngesikhathi sokwelashwa nge-Gensulin r, amacala angawodwa okwehla noma ukwanda kwenani lezicubu ezinamafutha kungenzeka. Inqubo efanayo ibonwa eduze kwezindawo zokujova. Kungenzeka ukugwema lesi simo ngokushintsha indawo yomjovo njalo.
Uma i-insulin isetshenziswa ngesikhathi sokukhulelwa, kubalulekile ukubheka ukuthi ku-trimester yayo yokuqala, isidingo se-hormone siyancipha, kuthi okwesibili nokwesithathu kukhuphuke kakhulu. Ngesikhathi sokuzalwa kwengane futhi ngokushesha emva kwabo, kungahle kube nokuntuleka kwesidingo somzimba sokujova kwama-hormone.
Uma owesifazane encelisa ibele, khona-ke kulokhu kufanele abe ngaphansi kokuqashwa kukadokotela (kuze kube isikhathi lapho isimo sizinza).
Iziguli ezinesifo sikashukela ezithola amayunithi angaphezu kwe-100 e-Gensulin P phakathi nosuku kufanele zilaliswe esibhedlela ngokushintshwa kwezidakamizwa.
Izinga lokuxhumana nezinye izidakamizwa
Ngokombono wokubukwa kwemithi, isidakamizwa asihambelani nezinye izidakamizwa.
I-Hypoglycemia ingacasulwa ngu:
- ama-sulfonamides;
- Mao inhibitors;
- i-carbonic anhydrase inhibitors;
- Ama-inhibitors e-ACE, ama-NSAID;
- ama-anabolic steroid;
- androgens;
- Amalungiselelo we-Li +.
Umphumela ohlukile esimweni sempilo yesifo sikashukela (ukuncishiswa kwe-hypoglycemia) uzoba nokusetshenziswa kweGensulin ngalezi zindlela:
- izindlela zokuvimbela inzalo ngomlomo;
- i-loop diuretics;
- ama-estrogens;
- insangu
- Ama-blocker e-H1 histamine receptor;
- i-nicotine;
- i-glucagon;
- somatotropin;
- epinephrine;
- i-clonidine;
- ama-anticepressants ama-tricyclic;
- morphine.
Kukhona izidakamizwa ezingathinta umzimba ngezindlela ezimbili. I-Pentamidine, i-octreotide, i-reserpine, kanye nama-beta-blockers angathuthukisa futhi enze buthaka umphumela we-hypoglycemic wesidakamizwa uGensulin r.