I-Gensulin: imiyalo nokubuyekezwa kokusetshenziswa

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IGensulin iyisisombululo somuthi sokujova isifo sikashukela. Kuphikisiwe uma kwenzeka uzwela ngokweqile kukho, kanye ne-hypoglycemia.

Imiyalo yokusebenzisa kanye nomthamo

Umthamo othize kanye nendlela yokuphatha izonconywa kuphela udokotela ohambelayo. Umthamo uzosethwa ngokugxila ekuhlolweni kashukela wegazi kanye namahora ama-2 ngemuva kokudla. Ngaphezu kwalokho, izinga lenkambo ye-glucosuria nezimpawu zayo kuzonakwa.

IGensulin r ingalawulwa ngezindlela ezahlukahlukene (ngaphakathi, ngaphakathi, ngaphakathi) imizuzu engu-15 kuya kwengama-30 ngaphambi kokudla okuhlosiwe. Indlela ethandwa kakhulu yokuphatha i-subcutaneous. Zonke ezinye zizolunga ezimweni ezinjalo:

  • nge-ketoacidosis yesifo sikashukela;
  • onesifo sikashukela;
  • ngesikhathi sokuhlinzwa.

Imvamisa yokuphatha ngesikhathi sokusebenzisa ukwelashwa kwezimoto izoba kathathu ngosuku. Uma kunesidingo, inani lemijovo lingakhushulwa lifinyelele ezikhathini ezi-5-6 ngosuku.

Ukuze ungathuthukisi i-lipodystrophy (i-atrophy ne-hypertrophy yezicubu ezingezansi), kuyadingeka ukuguqula indawo yomjovo njalo.

Umthamo ophakathi nsuku zonke wesidakamizwa Gensulin r uzoba:

  • ezigulini zabantu abadala - kusuka ema-30 kuye kwangama-40 amayunithi (UNITS);
  • ezinganeni - amayunithi ayi-8.

Ngaphezu kwalokho, ngesidingo esandayo, umthamo ojwayelekile uzoba ngu-0.5 - 1 UNITS ngekhilogremu yesisindo, noma ukusuka kuma-30 kuye kwangama-40 UNITS izikhathi ezi-3 ngosuku.

Uma umthamo wansuku zonke uzodlula ama-0.6 PIECES / kg, khona-ke kuleli cala umuthi kufanele uphathwe njengemijovo emi-2 ezingxenyeni ezahlukene zomzimba.

Umuthi uhlinzeka ngamathuba okuhlanganisa umuthi i-Gensulin r nama-insulin asebenza isikhathi eside.

Isixazululo kufanele siqoqwe kusuka ku-vial ngokubhoboza isithabisi senjoloba ngenaliti yesirinji oyinyumba.

Umgomo wokuchayeka emzimbeni

Lesi sidakamizwa sisebenzisana nama-receptors athile kulwelwesi lwangaphandle lwamaseli. Njengomphumela wokuxhumana okunjalo, kuvela i-insulin receptor complex. Njengoba ukukhiqizwa kwe-cAMP kukhuphuka kumaseli ezinamafutha nesibindi noma lapho kungena ngqo emangqamuzaneni emisipha, i-insulin receptor complex ephumayo iqala ukuvusa izinqubo ze-intracellular.

Ukwehla ushukela wegazi kubangelwa:

  1. ukukhula kwezokuhamba kwayo kwangaphakathi;
  2. ukumuncwa okuthe xaxa, kanye nokufakwa kwayo ngezicubu;
  3. ukugqugquzela inqubo ye-lipogenesis;
  4. synthesis amaprotheni;
  5. glycogenesis;
  6. ukwehla kwezinga lokukhiqizwa koshukela isibindi.

Ngemuva kokujova okufakwayo, umuthi iGensulin r uzoqala ukusebenza kungakapheli imizuzu engama-20 kuye kwengama-30. Ukuqoqwa okuphelele kwento kuzobhekwa ngemuva kwamahora angama-1-3. Isikhathi sokuchayeka kule insulin sizoncika ngqo kumthamo, indlela nasendaweni yokuphatha.

Amathuba okusabela okungekuhle

Ngenqubo yokusebenzisa i-Gensulin r ukusabela okungekuhle komzimba kungenzeka:

  • i-allergies (i-urticaria, ukuphefumula, umkhuhlane, ukwehlisa umfutho wegazi);
  • i-hypoglycemia (isikhumba sesikhumba, ukujuluka, ukukhukhula okwandayo, indlala, ukuthuthumela, ukukhathazeka ngokweqile, ikhanda, ukudangala, isimilo esingaziwa, ukubona okungalungile nokuxhumana);
  • i-hypoglycemic coma;
  • I-diabetesic acidosis ne-hyperglycemia (iba nemithamo enganele yesidakamizwa, ukweqa imijovo, ukwenqaba ukudla): I-hyperemia yesikhumba sobuso, ukwehla okukhulu kokudla, ukozela, ukoma okungapheli;
  • ukungazi kahle;
  • Izinkinga zombono wesikhashana;
  • ukusabela kwe-immunological komzimba kuyi-insulin yomuntu.

Ngaphezu kwalokho, ekuqaleni kokwelashwa, kungahle kube nokudumba futhi kuphazamiseke okungalungile. Lezi zimpawu azivezi futhi zisheshe zinyamalale.

Izici zohlelo lokusebenza

Ngaphambi kokuthatha umuthi i-Gensulin r kusuka ku-vial, udinga ukubheka isixazululo sobala. Uma kutholwa izidumbu zakwamanye amazwe, izidakamizwa noma udoti wento ethile, kwenqatshelwe ngokuphelele ukuyisebenzisa!

Kubalulekile ukuba ungakhohlwa mayelana lokushisa ekahle ikhambi injected - kumele kube lokushisa Igumbi.

Umthamo wesidakamizwa kufanele ulungiswe uma kwenzeka ukuthuthukiswa kwezifo ezithile:

  • ukutheleleka;
  • Isifo sika-Addison;
  • onesifo sikashukela ezigulini ezingaphezulu kweminyaka engama-65;
  • nezinkinga ekusebenzeni kwe-gland yegilo;
  • hypopituitarism.

Izimfuneko eziphambili zokuqalwa kwe-hypoglycemia zingaba: ukweqisa, ukuthathelwa izidakamizwa, ukuhlanza, ukucasuka kokugaya ukudla, ukuguqulwa kwesayithi lomjovo, ubunzima bomzimba kanye nokusebenzisana nezidakamizwa ezithile.

Ukwehla ushukela wegazi kungabonakala lapho ushintsha usuka ku-insulin yezilwane uye kumuntu.

Noma yiluphi ushintsho entweni ephathisiwe kufanele lube lolusemthethweni futhi lwenziwe ngaphansi kokubhekwa ngudokotela okuqine kakhulu. Uma kunenkambiso yokuthuthukisa i-hypoglycemia, khona-ke kuleli cala amandla eziguli ahlanganyele traffic traffic kanye nokugcinwa kwemishini, futhi ikakhulukazi ezimotweni, kungaba kukhubazeka.

Isifo sikashukela singamisa ngokuzimela ukuthuthukiswa kwe-hypoglycemia ethuthukayo. Lokhu kungenzeka ngenxa yokusetshenziswa kwenani lama-carbohydrate. Uma i-hypoglycemia idlulisiwe, ke kuyadingeka ukwazisa udokotela wakho ngalokhu.

Ngesikhathi sokwelashwa nge-Gensulin r, amacala angawodwa okwehla noma ukwanda kwenani lezicubu ezinamafutha kungenzeka. Inqubo efanayo ibonwa eduze kwezindawo zokujova. Kungenzeka ukugwema lesi simo ngokushintsha indawo yomjovo njalo.

Uma i-insulin isetshenziswa ngesikhathi sokukhulelwa, kubalulekile ukubheka ukuthi ku-trimester yayo yokuqala, isidingo se-hormone siyancipha, kuthi okwesibili nokwesithathu kukhuphuke kakhulu. Ngesikhathi sokuzalwa kwengane futhi ngokushesha emva kwabo, kungahle kube nokuntuleka kwesidingo somzimba sokujova kwama-hormone.

Uma owesifazane encelisa ibele, khona-ke kulokhu kufanele abe ngaphansi kokuqashwa kukadokotela (kuze kube isikhathi lapho isimo sizinza).

Iziguli ezinesifo sikashukela ezithola amayunithi angaphezu kwe-100 e-Gensulin P phakathi nosuku kufanele zilaliswe esibhedlela ngokushintshwa kwezidakamizwa.

Izinga lokuxhumana nezinye izidakamizwa

Ngokombono wokubukwa kwemithi, isidakamizwa asihambelani nezinye izidakamizwa.

I-Hypoglycemia ingacasulwa ngu:

  • ama-sulfonamides;
  • Mao inhibitors;
  • i-carbonic anhydrase inhibitors;
  • Ama-inhibitors e-ACE, ama-NSAID;
  • ama-anabolic steroid;
  • androgens;
  • Amalungiselelo we-Li +.

Umphumela ohlukile esimweni sempilo yesifo sikashukela (ukuncishiswa kwe-hypoglycemia) uzoba nokusetshenziswa kweGensulin ngalezi zindlela:

  1. izindlela zokuvimbela inzalo ngomlomo;
  2. i-loop diuretics;
  3. ama-estrogens;
  4. insangu
  5. Ama-blocker e-H1 histamine receptor;
  6. i-nicotine;
  7. i-glucagon;
  8. somatotropin;
  9. epinephrine;
  10. i-clonidine;
  11. ama-anticepressants ama-tricyclic;
  12. morphine.

Kukhona izidakamizwa ezingathinta umzimba ngezindlela ezimbili. I-Pentamidine, i-octreotide, i-reserpine, kanye nama-beta-blockers angathuthukisa futhi enze buthaka umphumela we-hypoglycemic wesidakamizwa uGensulin r.

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