I-Siofor 1000 yisidakamizwa esingeqembu leqembu lezindlela zokuqeda uhlobo lwe-2 sikashukela i-mellitus (esingathembela ku-insulin).
Umuthi wehlisa ushukela wegazi kubantu abadala, nasezinganeni ezisuka eminyakeni eyi-10 (abanesifo sikashukela sohlobo 2).
Ingasetshenziselwa ukwelapha iziguli ezinesisindo esikhulu somzimba ngaphansi kwesimo sokusebenza okunganele kokudla kokudla kanye nomsebenzi womzimba. Imiyalo yokusebenzisa umuthi ithi isiza ukunciphisa amathuba wokulimala kwesitho sikashukela esigabeni sabadala seziguli ezikhuluphele.
Umuthi ungasetjenziswa njenge-monotherapy wezingane kusuka eminyakeni eyi-10, kanye nabantu abadala. Ngaphezu kwalokho, iSiofor 1000 nayo ingasetshenziswa ngokuhambisana namanye ama-ejenti anciphisa ushukela wegazi. Sikhuluma ngemithi yomlomo, kanye ne-insulin.
I-contraindication esemqoka
Isidakamizwa asinconyelwe ukusetshenziswa ezimweni ezinjalo:
- kukhona ukuzwela okweqile kokuthile okusebenzayo okusebenzayo (metformin hydrochloride) noma ezinye izinto zomuthi;
- kuncike ekubonakalisweni kwezimpawu zokuxinaniswa ngemuva kwesifo sikashukela. Lokhu kungaba ukwanda okuqinile ekuqoqweni kwe-glucose egazini noma ku-oxidation ebalulekile yegazi ngenxa yokuqongelela kwemizimba ye-ketone. Isibonakaliso salesi simo sizoba nobuhlungu obukhulu emgodini wesisu, ukuphefumula okunzima kakhulu, ukozela, kanye nephunga elingajwayelekile, elingelona elemvelo elisuka emlonyeni;
- izifo zesibindi nezinso;
Izimo ezimbi kakhulu ezingadala isifo sezinso, ngokwesibonelo:
- izifo ezithathelwanayo;
- ukulahleka okukhulu koketshezi ngenxa yokuhlanza noma isifo sohudo;
- ukuhamba kwegazi okunganele;
- lapho kuba nesidingo sokwethula i-ejenti ehlukile equkethe iodine. Lokhu kungadingeka ezifundweni ezahlukahlukene zezokwelapha, njenge-x-ray;
Ngalezo zifo ezingadala ukulamba kwe-oxygen, isibonelo:
- ukwehluleka kwenhliziyo;
- umsebenzi wezinso ongonakalisiwe;
- ukuhamba kwegazi okunganele;
- ukuhlaselwa yinhliziyo kwakamuva;
- ngesikhathi sokudakwa kakhulu, kanye nophuzo oludakayo.
Uma kwenzeka ukhulelwe nokukhishwa, ukusetshenziswa kweSiofor 1000 nakho kwenqatshelwe. Ezimweni ezinjalo, udokotela ofanele kufanele asuse umuthi esikhundleni sokulungiselela i-insulin.
Uma okungenani esisodwa salezi zimo senzeka, kufanele wazise udokotela wakho ngakho.
Isicelo nomthamo
Umuthi i-Siofor 1000 kumele uthathwe ngendlela enembe kakhulu njengoba kuchazwe udokotela. Noma yikuphi ukubonakaliswa kokusabela okungalungile kufanele uthintane nodokotela.
Imithamo yemali kufanele inqunywe esimweni ngasinye ngazinye. Ukuqokwa kuzosuselwa kuliphi izinga le-glucose egazini. Lokhu kubaluleke kakhulu ekwelashweni kwazo zonke izigaba zeziguli.
I-Siofor 1000 ikhiqizwa ngefomethi yethebhulethi. Ithebhulethi ngayinye ihlanganiswa futhi iqukethe i-1000 mg ye-metformin. Ngaphezu kwalokho, kunefomu lokukhululwa kwalesi sidakamizwa ngesimo samaphilisi we-500 mg no-850 mg wento kuleyo naleyo.
Uhlobo olulandelayo lokwelashwa luzoba iqiniso
- ukusetshenziswa kweSiofor 1000 njengesidakamizwa esizimele;
- ukwelashwa okuhlanganisa kanye neminye imithi yomlomo enganciphisa ushukela wegazi (ezigulini zabantu abadala);
- ukusebenzisana ngokubambisana ne-insulin.
Iziguli zabantu abadala
Umthamo wokuqala ojwayelekile uzoba ngamacwecwe e-Cated camera (lokhu kuzofanela ama-500 mg we-metformin hydrochloride) izikhathi ezi-2 ngosuku noma ama-850 mg ento leyo izikhathi ezi-2 ngosuku (umthamo onjalo we-Siofor 1000 awunakwenzeka), imiyalo esetshenzisiwe kukhombisa ngokusobala.
Ngemuva kwezinsuku eziyishumi nanhlanu, udokotela ohambelayo uzolungisa umthamo odingekayo ngokuya nge-glucose egazini. Kancane kancane, umthamo wesidakamizwa uzokhuphuka, oba isihluthulelo sokubekezelela kangcono umuthi ovela ohlelweni lokugaya ukudla.
Ngemuva kokwenza ushintsho, umthamo uzoba kanjena: Ithebhulethi eyi-Siofor 1000, eboshwe, kabili ngosuku. IVolumu ekhonjisiwe izohambisana no-2000 mg we-metformin hydrochloride emahoreni angama-24.
Umthamo omkhulu wansuku zonke: Ithebhulethi eyi-1 iSiofor engu-1000, eboshwe, kathathu ngosuku Umthamo uzohambisana ne-3000 mg ye-metformin hydrochloride ngosuku.
Izingane ezivela eminyakeni eyi-10
Umthamo ojwayelekile wesidakamizwa ngu-0.5 g wethebhulethi ehlanganisiwe (lokhu kuzohambisana no-500 mg we-metformin hydrochloride) izikhathi ezi-2 ngosuku noma ama-850 mg ento ethekwini 1 ngosuku (umthamo onjalo awunakwenzeka).
Ngemuva kwamaviki ama-2, udokotela uzolungisa umthamo odingekayo, kusukela ekugxambeni kwe-glucose egazini. Kancane kancane, umthamo we-Siofor 1000 uzokhuphuka, oba isihluthulelo sokubekezelela kangcono umuthi ophuma emgodini wesisu.
Ngemuva kokwenza ushintsho, umthamo uzoba kanjena: Ithebhulethi eli-1, elihlanganisiwe, kabili ngosuku. Umthamo onjalo uzohambelana no-1000 mg we-metformin hydrochloride ngosuku.
Inani elikhulu lezinto ezisebenzayo kuzoba ngu-2000 mg, ohambelana nethebhulethi engu-1 yesidakamizwa uSiofor 1000, efakiwe.
Ukuphendula okungalungile kanye ne-overdose ngokweqile
Njenganoma yisiphi isidakamizwa, i-Siofor 1000 ingadala ukusabela okungekuhle, kepha ingaqala ukuthuthuka kude nazo zonke iziguli ezisebenzisa umuthi.
Uma ukweqisa komuthi sekwenzekile, ke esimweni esinjalo kufanele ngokushesha ufune usizo lodokotela.
Ukusetshenziswa kwethamo eliningi kakhulu akubangeli ukwehla ngokweqile ekujuleni kwe-glucose egazini (hypoglycemia), noma kunjalo, kungenzeka ukuthi kube ne-oxidation esheshayo yegazi lesiguli nge-lactic acid (lactate acidosis).
Kunoma yikuphi, ukunakekelwa okuphuthumayo nokwelashwa esibhedlela kuyadingeka.
Ukusebenzisana nezidakamizwa ezithile
Uma ukusetshenziswa kwalesi sidakamizwa kunikezwe, khona-ke kuleli cala kubaluleke kakhulu ukwazisa udokotela oholayo ngayo yonke leyo mithi esetshenziswa yiziguli ezinesifo sikashukela kuze kube muva nje. Kufanele usho ngisho namakhambi angaphezu kwe-counter.
Ngokwelashwa kweSifor 1000, kunethuba lamaconsi angalindelekanga kushukela wegazi ekuqaleni kokwenza, kanye nasekupheleliseni eminye imithi. Ngalesi sikhathi sesikhathi, ukugxila kweglucose kufanele kubhekwe ngokucophelela.
Uma okungenani kusetshenziswe okungenani eyodwa yezidakamizwa ezilandelayo, khona-ke lokhu akufanele kunganakwa udokotela:
- i-corticosteroids (cortisone);
- ezinye izinhlobo zemithi ezingasetshenziswa ngomfutho wegazi ophakeme noma ukusebenza kwemisipha yenhliziyo enganele;
- ama-diuretics asetshenziselwa ukwehlisa umfutho wegazi (i-diuretics);
- izidakamizwa zokuqeda i-asthma ye-bronchial (beta-sympathomimetics);
- ama-ejenti ahlukile aqukethe iodine;
- imithi equkethe utshwala;
Kubalulekile ukuxwayisa odokotela ngokusetshenziswa kwezidakamizwa ezinjalo ezingathinta kabi ukusebenza kwezinso:
- imithi ukwehlisa umfutho wegazi lakho;
- izidakamizwa ezinciphisa izimpawu zokutheleleka komoya okuphathelene nokuphefumula noma i-rheumatism (izinhlungu, umkhuhlane).
Izici zokusetshenziswa kwesidakamizwa i-Siofor 1000
Akuvamile ngokwanele, lapho usebenzisa iSifor 1000, ingozi yokuphuma kakhulu kwe-oxidation yegazi nge-lactic acid ingahle ikhule. Inqubo enjalo izobizwa nge-lactate acidosis.
Lokhu kwenzeka ngezinkinga ezinkulu ekusebenzeni kwezinso. Isizathu esiyinhloko salokhu kungaba ukuqongelela okungathandeki kwe-metformin hydrochloride emzimbeni wesifo sikashukela, imiyalo yokusebenzisa ikhombisa ngokuqondile leli phuzu.
Uma ungathathi izinyathelo ezifanele, khona-ke kunethuba eliphezulu lokukhohlisa, ukuqina kwesifo sikashukela kukhula.
Ukwehlisa ingozi yokuthola ukoma, kuyadingeka ukuthi unake ngokuphelele yonke imibiko ngokusetshenziswa kwe-Siofor 1000, futhi futhi ungakhohlwa ukulandela umthamo otuswe ngudokotela.
Ukubonakaliswa kwe-lactic acidosis kungafana nemiphumela emibi ye-metformin hydrochloride kusuka ohlelweni lokugaya ukudla:
- isifo sohudo
- izinhlungu ezibukhali emgodini wesisu;
- ukuphalaza okuphindaphindiwe;
- isicanucanu
Ngaphezu kwalokho, phakathi namasonto ambalwa, amathuba okuba nobuhlungu emisipha noma ukuphefumula ngokushesha kungenzeka. Ukugcwala kokuqwasha, kanye nokukhohlisa, nakho kungenzeka.
Uma lezi zimpawu zenzeka, khona-ke umuthi kufanele uyekwe futhi ufune usizo lodokotela ngokushesha. Kunezimo lapho ukwelashwa kudingeka esimweni sesibhedlela.
Into enkulu esebenzayo yesidakamizwa i-Siofor 1000 ikhishwa kanye nezinso. Ngenxa yalokhu, isimo somzimba kufanele sihlolwe ngaphambi kokuqala ukwelashwa. Ukuxilongwa kufanele kwenziwe okungenani isikhathi esisodwa ngonyaka, futhi uma kunesidingo esinjalo kaningi.
Qapha kakhulu umsebenzi wezinso ezimweni ezinjalo:
- iminyaka yesiguli ingaphezu kweminyaka engama-65;
- Ngasikhathi sinye, kwakusetshenziswa izidakamizwa ezidala ukuthi kube nomphumela olimazayo ekusebenzeni kwezinso.
Ngakho-ke, ngaso sonke isikhathi kufanele utshele udokotela ngayo yonke imishanguzo ephuziwe, ufunde ngokucophelela imiyalo esetshenzisiwe.
Ngokuya ngaphansi kokwethulwa kwe-ejenti ehlukile equkethe iodine, kunethuba lomsebenzi wezinso ongasebenzi kahle. Lokhu kuholela ekuphulweni kwe-excretion yento esebenzayo yesidakamizwa i-Siofor 1000.
Odokotela batusa ukumisa ukusetshenziswa komuthi uSiofor izinsuku eziyi-1000 ngaphambi kwezinsuku ze-x-ray noma ezinye izifundo. Ukuqala kabusha kokusetshenziswa kwomuthi kuqala ngemuva kwamahora angama-48 ngemuva kokubamba eyodwa.
Uma ukungenelela okuhleliwe kuhlinzekwe kusetshenziswa i-anesthesia noma i-anesthesia ye-cerebrospinal, khona-ke kulokhu ukusetshenziswa kwe-Siofor 1000 nakho-ke kumisiwe .. Njengasezindabeni ezedlule, umuthi ukhanselwa ezinsukwini ezi-2 ngaphambi kokukhohliswa.
Ungaqhubeka nokuwuthatha kuphela ngemuva kokuphinda usebenzise amandla noma ungasheshe ukwedlula amahora angama-48 ngemuva kokuhlinzwa. Kodwa-ke, ngaphambi kokuba udokotela ahlole izinso. Ngaphezu kwalokho, kubalulekile ukubheka umsebenzi wesibindi.
Uma udla utshwala, ingozi yokuncipha okubukhali kwe-glucose nokukhula kwe-lactic acidosis kukhuphuka kaningana. Ngenxa yalokhu, isidakamizwa notshwala akuhambelani ngokuphelele.
Ukuphepha kokuphepha
Ngesikhathi sokwelashwa ngosizo lwe-Siofor 1000 ukulungiselela, kuyadingeka ukunamathela ekudleni okuthile futhi unake kakhulu ukusetshenziswa kokudla kwe-carbohydrate. Kubalulekile ukudla ukudla okunokuqukethwe okuphezulu kwesitashi ngokulinganayo ngangokunokwenzeka:
- amazambane
- I-pasta
- izithelo
- fig.
Uma isiguli sinomlando wesisindo somzimba ngokweqile, khona-ke udinga ukunamathela ekudleni okukhethekile kwekhalori. Lokhu kufanele kwenzeke ngaphansi kokunakwa udokotela okukhona naye.
Ukuqapha inkambo yesifo sikashukela, kufanele njalo uhlole igazi ngoshukela.
I-Siofor 1000 ayinakubangela i-hypoglycemia. Uma isetshenziswa kanyekanye nezinye izidakamizwa zesifo sikashukela, amathuba okuba wehle kakhulu emazingeni kashukela egazini angakhuphuka. Sikhuluma ngamalungiselelo we-insulin ne-sulfonylurea.
Izingane ezisukela eminyakeni engu-10 ubudala nentsha
Ngaphambi kokunquma ukusetshenziswa kweSiofor 1000 kuleli qembu leminyaka, i-endocrinologist kumele iqinisekise ubukhona besifo sikashukela sohlobo 2 esigulini.
Ukwelashwa ngosizo lomuthi lwenziwa ngokulungiswa kokudla, kanye nokuxhumeka nokuzivocavoca umzimba okujwayelekile.
Njengomphumela wocwaningo lwezokwelapha olulawulwa unyaka owodwa, umphumela wesithako esikhulu esisebenzayo somuthi uSiofor 1000 (metformin hydrochloride) ekukhuleni, ekukhuleni nasekukhuleni kwezingane awukasungulwa.
Okwamanje, akusekho izifundo ezenziwayo.
Lokhu kuhlolwa kufaka phakathi izingane ezineminyaka eyi-10 kuye kwayi-12.
Abantu abadala
Ngenxa yokuthi ezigulini esezikhulile, ukusebenza kwezinso kuvame ukungasebenzi, umthamo weSiofor 1000 kufanele ulungiswe. Ukuze wenze lokhu, esibhedlela, kuhlolwa izinso njalo.
Imiyalo ekhethekile
ISiofor 1000 ayikwazi ukuthinta amandla okushayela kahle izimoto futhi ayithinti ikhwalithi yendlela yokusebenza.
Ngaphansi kwesimo sokusetshenziswa ngasikhathi sinye nezinye izidakamizwa ekwelapheni isifo sikashukela i-mellitus (insulin, repaglinide noma i-sulfonylurea), kungahle kube nokuhlukumezeka kwekhono lokushayela izimoto ngenxa yokwehla kwenhliziyo egazini likashukela.
Khipha ifomu iSiofor 1000 nezimo zokugcina eziyisisekelo
ISiofor 1000 ikhiqizwa emaphaketheni amathebulethi ayi-10, 30, 60, 90 noma ayi-120, ahlanganiswe. Kwinethiwekhi yamakhemikhali, akuwona wonke amasayizi wokufaka alolu hlobo 2 wesifo sikashukela angalethwa.
Gcina umuthi ezindaweni lapho kungekho khona izingane. Ukusetshenziswa kwesidakamizwa uSiofor yizingane eziyi-1000 kufanele kwenzeke ngaphansi kokuqashwa okuqinile kwabantu abadala.
Umuthi awukwazi ukusetshenziselwa ukwelashwa ngemuva kosuku lokuphelelwa yisikhathi, olukhonjisiwe ku-blister noma epakethe ngalinye.
Isikhathi sokusetshenziswa kungenzeka siphela ngosuku lokugcina lwenyanga olubhalwe kwiphakheji.
Azikho izimo ezikhethekile zokugcinwa komuthi uSiofor 1000.
