Kanye ngesonto, kusiza ukusebenzisa usuku lokuzibheka ngokuphelele ushukela, futhi udinga nokuhlolwa kwelebhu, umchamo, ukuhlolwa njalo kwe-ultrasound nezinye izivivinyo.
Kungani uhlolelwa isifo sikashukela
Ukuhlaziywa kufanele kuthathwe njalo, ngoba ngosizo lwabo ungaphendula imibuzo elandelayo:
- Ngabe ulimele kangakanani ama-pancreas uma uqukethe amaseli akhiqiza i-insulin?
- Ngabe izindlela zokuwelapha ziletha muphi umphumela futhi zithuthukisa ukusebenza kwe-gland? Ngabe liyanda inani lamaseli e-beta futhi ingabe ukwakheka kwe-insulin emzimbeni kuyanda?
- Yibuphi ubunzima bezinkinga zesifo sikashukela esivele sebeqalile ukuzikhulisa?
- Indaba ebalulekile isimo sezinso.
- Iyini ingozi yezinkinga ezintsha zesifo? Ingabe kukhona ukuncishiswa kwengozi ngenxa yokwelashwa? Okubaluleke kakhulu umbuzo wokuthi amathuba wokuhlaselwa yinhliziyo noma unhlangothi.
Isifo sikashukela sidinga ukuthi izivivinyo zinikezwe njalo futhi imiphumela yazo ikhombisa ngokusobala ukuthi umphumela omuhle ubonwa kanjani ngokubuka umbuso kanye nokugcina ushukela ozinzile ushukela egazini.
Inani elikhulu lezinkinga ekutholakaleni i-mellitus yesifo sikashukela ziyavimbeka, kanye nentuthuko ehlehlisayo. Imiphumela emihle yokwelashwa kukashukela itholakala kusetshenziswa ukudla okune-carbohydrate nezinye izindlela. Bangaba ngcono kakhulu kunendlela ejwayelekile "yendabuko". Imvamisa, ngesikhathi esifanayo, ukuhlolwa kuqala ukwenziwa ngcono, bese isiguli siphawula ukuthuthuka enhlalakahleni.
Glycated hemoglobin assay
Lokhu kuhlaziya kumele kuthathwe kabili ngonyaka uma isiguli singayitholi i-insulin. Uma isifo sikashukela silungiswa ngamalungiselelo e-insulin, khona-ke lokhu kufanele kwenziwe kaningi (amahlandla amane ngonyaka).
Ukuhlolwa kwegazi kwe-glycated hemoglobin HbA1C ilungele kakhulu ukutholakala kokuqala kwesifo sikashukela. Kepha uma ubhekisisa ukwelashwa kwalesi sifo ngosizo lwayo, kufanele kukhunjulwe into eyodwa - inani le-HbA1C libonisa isilinganiso esimaphakathi sikashukela egazini ezinyangeni ezintathu ezedlule, kepha asinikezi imininingwane ngokushintshashintsha kwezinga layo.
Uma phakathi kwalezi zinyanga isiguli besilokhu sinezifo ezijwayelekile kumazinga kashukela, khona-ke lokhu kuzothinta impilo yakhe. Ngaphezu kwalokho, uma isilinganiso seglucose besisondele kokujwayelekile, khona-ke ukuhlaziya kwe-hemoglobin ye-glycated ngeke kuveze lutho.
Ngakho-ke, uma kukhona i-mellitus yesifo sikashukela, ukwenza lokhu kuhlaziya akususi isidingo esiqhubekayo sokuthola ushukela wakho wegazi nge-glucometer nsuku zonke kanye nezikhathi eziningana.
Ukuhlolwa kwegazi kwe-C-peptide
I-C-peptide iprotheni ekhethekile ehlukanisa i-molecule ye- "proinsulin" lapho yakha i-insulin kuma-pancreas. Ngemuva kokwehlukana, yena ne-insulin bangena egazini. Okusho ukuthi, uma le protein ibonwe egazini, khona-ke i-insulin yayo iyaqhubeka nokwakheka emzimbeni.
Ukuphakama kokuqukethwe kwe-C-peptide esegazini, kuba ngcono ukusebenza kwamanyikwe. Kodwa ngasikhathi sinye, uma ukuqoqwa kwe-peptide kungaphezu kokujwayelekile, lokhu kubonisa ukwanda kwe-insulin. Lesi simo sibizwa nge-hyperinsulinism. Lokhu kuvame ukutholakala ezigabeni zokuqala zokukhula kwesifo sikashukela sohlobo 2 noma esimweni sokubekezelelwa kwe-prediabetes (ukubekezelela ushukela).
Kungcono ukuthatha lokhu kuhlaziya ekuseni ngesisu esingenalutho futhi udinga ukukhetha isikhashana lapho ushukela wegazi uvamile futhi ungaphakanyisiwe. Ngasikhathi sinye nalolu cwaningo, kufanele udlulise ukuhlaziywa kwe-plasma glucose noma ngokuzimela ukukala ushukela wegazi. Ngemuva kwalokho, udinga ukuqhathanisa imiphumela yokuhlaziya kokubili.
- Uma izinga likashukela wegazi lilijwayelekile, futhi okuqukethwe yi-C-peptide kuphakanyisiwe, khona-ke lokhu kubonisa ukumelana ne-insulin, isigaba sokuqala noma isifo sokuqala sikashukela sohlobo 2. Kulokhu, udinga ukuqala ukwelashwa ngendlela okufika ngesikhathi usebenzisa ukudla okune-carbohydrate ephansi, uma kunesidingo, xhuma ukuzivocavoca kanye namaphilisi weSiofor. Musa ukujaha ukushintshela kumijovo ye-insulin, ngoba kungenzeka ukuthi kunokwenzeka okukhulu ngaphandle kwesilinganiso esinjalo.
- Uma zombili i-C-peptide noshukela wegazi ziphakanyisiwe, lokhu kubonisa uhlobo lwesifo sikashukela “esithuthukile”. Kodwa noma kwesinye isikhathi ingalawulwa ngempumelelo ngaphandle kokusebenzisa i-insulin usebenzisa izindlela ezingenhla, kuphela ukubona uhlobo lwesiguli kufanele kuyalwe ngokwengeziwe.
- Uma i-C-peptide iqukethe amanani amancane futhi ushukela uyaphakanyiswa, lokhu kukhombisa ukulimala okukhulu kumanyikwe. Lokhu kwenzeka ngesifo sikashukela sohlobo 2 esezingeni eliphezulu noma uhlobo 1 sikashukela. Kulokhu, kuba nesidingo ukusebenzisa i-insulin.
Ukuhlolwa kwegazi kokuqukethwe kwe-C-peptide ku-serum kufanele kuthathwe ekuqaleni kokwelashwa kwesifo sikashukela. Esikhathini esizayo, ingashiywa futhi ngaleyo ndlela wonge imali uma kunesidingo.
Ukuhlolwa kwegazi okujwayelekile kanye ne-biochemistry yegazi
I-biochemistry yegazi ifaka iqoqo lonke lezivivinyo ezivame ukuphumelela phakathi kokuhlolwa kwezokwelapha. Bayadingeka ukuthola izifo ezifihliwe emzimbeni womuntu ezingaba khona ngaphandle kwesifo sikashukela, futhi bathathe nezinyathelo ezifika ngesikhathi zokwelashwa kwabo.
Ilabhorethri inquma okuqukethwe yizinhlobo ezahlukahlukene zamaseli egazini - ama-platelet, amangqamuzana amhlophe abomvu egazi. Uma kunamaseli wegazi amhlophe amaningi, lokhu kukhombisa ukuba khona kwenqubo yokuvuvukala, okungukuthi, kuyadingeka ukubona nokwelapha ukutheleleka. Amazinga aphansi amangqamuzana abomvu egazi awuphawu lwe-anemia.
Izici ezibangela isifo sikashukela sohlobo 1 zivame ukubangela ukwehluleka kwe-thyroid. Ukuba khona kwenkinga enjalo kuboniswa ukwehla kwenani lamaseli amhlophe egazi.
Uma ukuhlolwa kwegazi okujwayelekile kukhombisa ukuthi umsebenzi we-yegilo yegilo ungenziwa buthaka, kufanele futhi uhlole ama-hormone ayo. Kubalulekile ukukhumbula ukuthi ukuhlolwa kwe-yegilo yegilo akubandakanyi kuphela ekuhlaziyeni kwe-hormone ekhuthaza i-thyroid, kodwa futhi nokuqukethwe kwamanye ama-hormone - i-T3 yamahhala ne-T4 yamahhala - kumele kunqunywe.
Izimpawu zokuthi izinkinga seziqale ku-yegilo yegilo kungukugcwala kwemisipha, ukukhathala okungamahlalakhona, nokupholisa kwemilenze. Ikakhulu uma ukukhathala kungahambi ngemuva kokuthi ushukela wegazi esebuyiselwe ngokusebenzisa ukudla okune-carbohydrate ephansi.
Ukuhlaziywa kokunqunywa kwama-hormone egilo kumele kwenziwe uma kukhona ubufakazi balokhu, yize kubiza kakhulu. Indlala yegilo ibuyiselwa esimweni esejwayelekile ngosizo lwamaphilisi anqunywe yi-endocrinologist.
Ngenqubo yokwelashwa, isimo seziguli sithuthukisa kakhulu, ngakho-ke, imali esetshenzisiwe, imizamo kanye nesikhathi kuvunyelwa ngomphumela.
I-Serum ferritin
Le nkomba ikuvumela ukuthi unqume izitolo zensimbi emzimbeni. Imvamisa lokhu kuhlaziya kwenziwa uma kukhona izinsolo zokuthi isiguli sinemizwa ngenxa yokushoda kwe- iron. Kodwa-ke, akubona bonke odokotela abaziyo ukuthi ukweqiwa kwensimbi ngokweqile kungadala ukwehla kokulimazeka kwezicubu ze-insulin, okungukuthi, ukumelana ne-insulin.
Ngaphezu kwalokho, i-serum ferritin iholela ekubhujisweni kwezindonga zemithambo yegazi futhi yenyusa amathuba wokuhlaselwa yinhliziyo. Ngakho-ke, ukuhlaziya kwaleli khompiyutha kufanele kuthathwe lapho kwenziwa yonke inkimbinkimbi ye-biochemistry yegazi.
Uma imiphumela ikhombisa ukuthi umzimba uqukethe i-iron eningi, khona-ke umuntu angaba ngumnikeli wegazi. Lesi silinganiso sikuvumela ukuthi welaphe ukumelana ne-insulin futhi ukuvikela kokuhlaselwa yinhliziyo, njengoba umzimba ususa i-iron ethe xaxa.
ISerum Albumin
Imvamisa, lolu cwaningo lufakiwe kwi-biochemistry yegazi. Amazinga aphansi we-serum albhamuin ayiphinda kabili ingozi yokushona kwabantu okubangelwa izimbangela ezahlukahlukene. Kepha akubona bonke odokotela abaziyo ngalokhu. Uma imiphumela yokuhlaziywa iveza ukuthi i-serum albhamuin yehlisiwe, khona-ke imbangela kufanele ifunwe futhi ilashwe.
Ukuhlolwa kwegazi kwe-magnesium nge-hypertension
Uma umuntu enomfutho wegazi ophakeme, ke, ngokwesibonelo, eMelika, kuhlolwa igazi ngenani le-magnesium kumaseli egazi abomvu. Ezweni lethu, lokhu akukamukelwa. Lolu cwaningo akumele lube nokudidaniswa nokuhlaziywa kwe-plasma ye-magnesium, okungathembekile, ngoba noma kunokuntuleka kwe-magnesium, imiphumela yokuhlaziywa izoba yinto ejwayelekile.
Ngakho-ke, uma umuntu ene-hypertension, kepha izinso zisebenza ngokujwayelekile, lapho-ke nje udinga ukuqala ukuthatha iMagne-B6 kwimithamo emikhulu nasemavikini amathathu kamuva ukuhlola ukuthi impilo yakho ithuthukile yini.
I-Magne-B6 iyanconywa ukuthi isetshenziswe cishe yibo bonke abantu (80-90%). Lawa maphilisi okwehlisa ushukela wegazi abe nomphumela olandelayo:
- umfutho wegazi ophansi;
- neqhaza ekuthuthukeni kwe-arrhythmias, tachycardia nezinye izinkinga zenhliziyo;
- khulisa ukuthikamezeka kwezicubu kwe-insulin;
- thuthukisa ukulala, ukuzola, ukuqeda ukungaphatheki kahle;
- lawula ipheshana lokugaya ukudla;
- lula isimo sabesifazane abane-premenstrual syndrome.
